Bihui Pan, Zhangdi Xu, Kaixin Du, Rui Gao, Jiale Zhang, Hua Yin, Haorui Shen, Jinhua Liang, Yue Li, Li Wang, Jianyong Li, Wei Xu, Jiazhu Wu
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the West. With CLL's heterogeneity, some people still develop disease refractory and relapse despite advances in treatment. Thus, early diagnosis and treatment of high-risk CLL patients is critical. Fatty acid (FA) metabolism contributes to tumorigenesis, progression, and therapy resistance through enhanced lipid synthesis, storage, and catabolism. In this study, we aimed to construct a prognostic model to improve the risk stratification of CLL and reveal the link between FA metabolism and CLL...
December 27, 2023: Annals of Hematology