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Samantha F Pickles, David I Pritchard
Alimentary products of medicinal Lucilia sericata larvae are studied to determine their mechanisms of action, particularly in the contexts of wound debridement and disinfection. Furthermore, the larvae can be applied to patients in contained medical devices (such as the BioBag; BioMonde). Here, we tested the materials and larval content of the most commonly used debridement device (the "BB-50") to explore the possibility that endotoxins may be contributing to the bio-activity of the product, given that endotoxins are potent stimulants of cellular activation...
May 2017: Wound Repair and Regeneration
Jonathan Winfield, Lily D Chambers, Jonathan Rossiter, Ioannis Ieropoulos
The long and short-term stability of two porous dependent ion exchange materials; starch-based compostable bags (BioBag) and ceramic, were compared to commercially available cation exchange membrane (CEM) in microbial fuel cells. Using bi-directional polarisation methods, CEM exhibited power overshoot during the forward sweep followed by significant power decline over the reverse sweep (38%). The porous membranes displayed no power overshoot with comparably smaller drops in power during the reverse sweep (ceramic 8%, BioBag 5...
November 2013: Bioresource Technology
Ying Yan, Tao He, Yin Shen, Xiao Chen, Bo Diao, Zhi Li, Fang Zhou, Yi-Qiao Xing
PURPOSE: To establish and evaluate a novel in vitro model of retinal ischemia, and to determine whether an autocrine pathway of retinal microvascular endothelial cells (RMVECs) by vascular endothelial growth factor (VEGF) signaling plays a role based on this model. METHODS: Primary RMVECs were isolated from the retinas of C57/BL6J rats and identified by an evaluation for FITC-marked CD31. The hypoxia models were established with the biobag at the time of 12, 24, 48 and 72 h, and evaluated with a blood-gas analyzer...
2013: Ophthalmic Research
James D Simons, Charles R Smith
The Texas National Coastal Assessment (NCA) program began with the immediate challenge of integrating the NCA effort with Texas Parks and Wildlife Department's (TPWD) Coastal Fisheries Division and its existing probabilistic Fishery Independent Monitoring Program. Close coordination and detailed planning along with a novel two boat sampling operation helped to make this alliance work. Partnerships with National Estuary Programs and the Texas Commission on Environmental Quality (TCEQ) greatly improved coverage of the Texas coast over the initial fifty station design...
March 2009: Environmental Monitoring and Assessment
Felix A S Blake, Norbert Abromeit, Michael Bubenheim, Lei Li, Rainer Schmelzle
The use of maggot therapy is experiencing a revival in the treatment of problem wounds. Although this alternative therapy is ancient, little scientific research has been aimed at standardizing this therapy. The purpose of our investigation was to determine the debridement efficiency of this therapy, i.e., to compare the use of freely crawling maggots with maggots in a Biobag and to estimate the amount of maggots needed for debridement. We designed an artificial wound model and investigated the rate of decomposition of porcine tissue...
September 2007: Wound Repair and Regeneration
G N Jukema, P Steenvoorde, C Y Wong, A T Bernards, J T van Dissel
The ancient method of larval therapy for treatment of acute and chronic infections has become a revival and a new dimension with introduction of the Biobag (Vitapad). With use of this therapy trauma patients suffering infectious complications can be treated very effective, which can reduce the overall time needed for treatment and can result in diminished invalidity.
April 2006: Zentralblatt Für Chirurgie
Simon F Preuss, Mark J Stenzel, Anwar Esriti
BACKGROUND: The use of maggots to digest necrotic tissue as a form of wound debridement has a long history in medicine. Necrotizing fasciitis of the neck has a high mortality rate despite aggressive surgical and medical intervention. The use of maggots in this disease has been reported only once before. METHODS: We report the case of a 73-year-old woman, who underwent neck dissection and had necrotizing fasciitis of the neck develop shortly after. After initial surgical wound debridement, we used maggots as a biosurgical method for further debridement...
August 2004: Head & Neck
D I Grove, R A McLeay, K E Byron, G Koutsouridis
Multiple gastric biopsies were taken from 288 patients in Port Lincoln, South Australia. One biopsy was used for a CLOtest and the other three were transported to a central laboratory in Adelaide in physiological saline, Portagerm pylori transport medium or after culture on a chocolate agar plate which was placed in a Biobag. Helicobacter pylori was isolated from 18.3% of patients. There was a 95.7% concordance between culture results and the CLOtest result. Recovery rates after transport on chocolate agar, Portagerm pylori and in saline were 90...
August 2001: Pathology
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