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Abdominal imaging, hcc

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https://www.readbyqxmd.com/read/29456411/clinical-utility-of-hepatitis-b-surface-antigen-kinetics-in-treatment-na%C3%A3-ve-chronic-hepatitis-b-patients-during-long-term-entecavir-therapy
#1
Tien-Ching Lin, Yen-Cheng Chiu, Hung-Chih Chiu, Wen-Chun Liu, Pin-Nan Cheng, Chiung-Yu Chen, Ting-Tsung Chang, I-Chin Wu
AIM: To investigate the utility of hepatitis B surface antigen (HBsAg) kinetics in chronic hepatitis B patients during long-term entecavir treatment. METHODS: This retrospective study included treatment-naïve chronic hepatitis B patients who received at least 2 years of consecutive entecavir treatment. Patients were followed up at three to six month intervals with liver biochemistry, hepatitis B virus DNA, and abdominal sonography. In hepatitis B e antigen (HBeAg)-positive patients, HBeAg levels were assessed every three to six month until results became negative...
February 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29399277/fatty-liver-disease-an-emerging-etiology-of-hepatocellular-carcinoma-in-argentina
#2
Federico Piñero, Josefina Pages, Sebastián Marciano, Nora Fernández, Jorge Silva, Margarita Anders, Alina Zerega, Ezequiel Ridruejo, Beatriz Ameigeiras, Claudia D'Amico, Luis Gaite, Carla Bermúdez, Manuel Cobos, Carlos Rosales, Gustavo Romero, Lucas McCormack, Virginia Reggiardo, Luis Colombato, Adrián Gadano, Marcelo Silva
AIM: To investigate any changing trends in the etiologies of hepatocellular carcinoma (HCC) in Argentina during the last years. METHODS: A longitudinal cohort study was conducted by 14 regional hospitals starting in 2009 through 2016. All adult patients with newly diagnosed HCC either with pathology or imaging criteria were included. Patients were classified as presenting non-alcoholic fatty liver disease (NAFLD) either by histology or clinically, provided that all other etiologies of liver disease were ruled out, fatty liver was present on abdominal ultrasound and alcohol consumption was excluded...
January 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29394753/-multidisciplinary-therapy-for-hepatocellular-carcinoma-with-peritoneal-dissemination
#3
Natsuko Yamauchi, Masahiro Kido, Shohei Komatsu, Motofumi Tanaka, Hisoka Kinoshita, Daisuke Tsugawa, Masafumi Awazu, Kimihiko Ueno, Hirochika Toyama, Sachio Terai, Hideyo Mukubou, Tetsuo Ajiki, Takumi Fukumoto
We report a case of bilobar multiple hepatocellular carcinoma(HCC)with peritoneal dissemination successfullytreated by dual treatment with reductive surgeryplus percutaneous isolated hepatic perfusion(PIHP). A 73-year-old man had sudden abdominal pain and was diagnosed bilobar multiple HCC through some examinations. The abdominal CT scan demonstrated onlya peritoneal dissemination under the liver. We performed partial hepatectomyof the lateral segment and the Spiegel lobe, and resected a peritoneal dissemination...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29372848/hepatic-epithelioid-hemangioendothelioma
#4
Lynette L Studer, Dale M Selby
Epithelioid hemangioendothelioma is a rare vascular tumor, composed of epithelioid and histiocytoid vascular endothelial cells in myxoid or fibrotic stroma, which can arise in multiple locations throughout the body. In the liver, this neoplasm usually presents on imaging as an incidental finding of multifocal, heterogeneously enhancing nodules in both lobes or presents clinically with nonspecific abdominal symptoms. Histologically, the tumor has been mistaken for metastatic carcinoma, angiosarcoma, hepatocellular carcinoma, and cholangiocarcinoma...
February 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29317591/an-unusual-presentation-of-advanced-intrahepatic-cholangiocarcinoma-when-biopsy-results-fail
#5
Joseph J Tasch, Nirva Dube
BACKGROUND Intrahepatic cholangiocarcinoma is a rare condition which typically occurs in males between 50 and 70 years of age, and presents with symptoms related to biliary obstruction including jaundice, pruritus, and dark urine. Other common symptoms at presentation include abdominal pain, weight loss, and fever. CASE REPORT We present a case of a 67-year-old female initially presenting with chest pain at rest, found to have a lung nodule on diagnostic imaging at the time of admission. On further imaging, a 9 cm liver lesion was incidentally discovered, initially suspicious for hepatocellular carcinoma on imaging, with initial biopsy staining CK7 positive, and CK20 negative...
January 10, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29312871/patient-specific-three-dimensional-printing-for-pre-surgical-planning-in-hepatocellular-carcinoma-treatment
#6
Elizabeth Perica, Zhonghua Sun
Background: Recently, three-dimensional (3D) printing has shown great interest in medicine, and 3D printed models may be rendered as part of the pre-surgical planning process in order to better understand the complexities of an individual's anatomy. The aim of this study is to investigate the feasibility of utilising 3D printed liver models as clinical tools in pre-operative planning for resectable hepatocellular carcinoma (HCC) lesions. Methods: High-resolution contrast-enhanced computed tomography (CT) images were acquired and utilized to generate a patient-specific 3D printed liver model...
December 2017: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29310401/ectopic-hepatocellular-carcinoma-manifesting-multiple-abdominal-masses-a-case-report
#7
RenAn Jin, Qingsong Yu, Xiao Liang
RATIONALE: Ectopic hepatocellular carcinoma (HCC) is a rare disease that mostly originates from an ectopic liver. PATIENT CONCERNS: The patient was admitted with upper abdominal distention for 3 months, which aggravated after meal. DIAGNOSES: A contrast-enhanced computed tomography (CT) scan revealed multiple abdominal masses. After exploratory laparotomy and histological examination, the patient was diagnosed as ectopic HCC. INTERVENTIONS: Exploratory laparotomy was performed for the purpose of diagnosis and treatment...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29244227/surveillance-for-hepatobiliary-cancers-in-patients-with-primary-sclerosing-cholangitis
#8
Ahmad Hassan Ali, James H Tabibian, Navine Naser-Ghodsi, Ryan J Lennon, Thomas DeLeon, Mitesh J Borad, Moira Hilscher, Marina G Silveira, Elizabeth J Carey, Keith D Lindor
BACKGROUND AND AIMS: Primary sclerosing cholangitis (PSC) is a risk factor for cholangiocarcinoma (CCA) and gallbladder carcinoma (GBCa). Surveillance for GBCa is recommended, but the clinical utility of surveillance for other hepatobiliary cancers (HBCa) in PSC, namely CCA and hepatocellular carcinoma (HCC), is unclear. We aimed to determine whether surveillance is associated with better survival after diagnosis of HBCa in patients with PSC. METHODS: Medical records of PSC patients seen at Mayo Clinic Rochester from 1995-2015 were reviewed...
December 15, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29187023/biopsy-proven-hepatocellular-carcinoma-in-a-53-year-old-woman-with-arginase-deficiency
#9
Matthew Koo, Gerald S Lipshutz, Stephen D Cederbaum, Charles Lassman
Arginase 1 deficiency, the least common urea cycle disorder, commonly presents with childhood-onset spastic paraplegia, progressive neurologic impairment, epilepsy, and developmental delay or regression. Biopsy-proven cirrhosis and hepatocellular carcinoma diagnosed via clinical and imaging studies (but without biopsy confirmation) have been previously reported. We report, herein, a case of a 53-year-old woman with arginase 1 deficiency who developed symptoms of "abdominal bloating." Imaging studies (ultrasound and magnetic resonance imaging) demonstrated 2 dominant hepatic masses, measuring 5...
January 1, 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/29175528/excellent-outcomes-of-liver-transplantation-following-down-staging-of-hepatocellular-carcinoma-to-within-milan-criteria-a-multi-center-study
#10
Neil Mehta, Jennifer Guy, Catherine T Frenette, Jennifer L Dodge, Robert W Osorio, William B Minteer, John P Roberts, Francis Y Yao
BACKGROUND & AIMS: Single-center studies have reported excellent outcomes of patients who underwent liver transplantation for hepatocellular carcinoma (HCC) after successful down-staging (reduction of tumor burden with local-regional therapy), but multi-center studies are lacking. We performed a multi-center study, applying a uniform down-staging protocol, to assess outcomes of liver transplantation and performed an intention to treat analysis. We analyzed factors associated with treatment failure, defined as dropout from the liver transplant waitlist due to tumor progression, liver-related death without transplant, or recurrence of HCC after transplant...
November 23, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29166330/hepatic-falciform-artery-demonstrating-maa-uptake-in-the-anterior-abdomen-prior-to-embolization
#11
Dhruv Patel, Ken Le, Joga Chaganti, Robert Mansberg
A 58-year-old man was referred for selective internal radiation therapy for locally advanced unresectable hepatocellular carcinoma. Intra-arterial particle perfusion scintigraphy was performed with SPECT/CT following intra-arterial injection of Tc macroaggregated albumin. Angiography demonstrated a hepatic falciform artery, a feeding artery of the ligamentum teres, whereas scintigraphy demonstrated tracer uptake in the mid-anterior abdominal wall. The hepatic falciform artery was subsequently embolized and the repeat angiogram confirmed successful occlusion...
January 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29151285/-afp-producing-gastric-cancer-and-hepatoid-gastric-cancer
#12
Y K Wang, X T Zhang
AFP-producing gastric cancer(AFPGC) and hepatoid adenocarcinoma of the stomach (HAS) are two special subtypes of gastric cancer. There are both correlation and difference between them. AFPGC is usually identified as primary gastric cancer with serum AFP level more than 20 ng/ml or showed AFP positive staining by immunohistochemistry. The diagnosis of HAS is mainly dependent on the pathological character of hepatocellular carcinoma-like differentiation of gastric cancer. The morbidity of AFPGC and HAS are rather low, especially the incidence of HAS is about 1%...
November 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29134355/extracellular-contrast-agent-enhanced-mri-15-min-delayed-phase-may-improve-the-diagnostic-performance-for-hepatocellular-carcinoma-in-patients-with-chronic-liver-disease
#13
Si Eun Lee, Chansik An, Shin Hye Hwang, Jin-Young Choi, Kyunghwa Han, Myeong-Jin Kim
OBJECTIVES: To determine the value of a 15-min delayed phase in extracellular contrast agent (ECA)-enhanced magnetic resonance imaging (MRI) for evaluation of hepatocellular carcinoma (HCC) in patients with chronic liver disease. METHODS: Between 2014 and 2015, 103 patients with chronic liver disease underwent ECA-enhanced MRI; 133 lesions consisting of 107 HCCs, 23 benign lesions and three non-HCC malignancies were identified with pathological or clinical diagnosis...
November 13, 2017: European Radiology
https://www.readbyqxmd.com/read/29082453/rapidly-growing-hepatocellular-carcinoma-after-direct-acting-antiviral-treatment-of-chronic-hepatitis-c
#14
Toshihiro Kawaguchi, Tatsuya Ide, Hironori Koga, Reiichiro Kondo, Ichiro Miyajima, Teruko Arinaga-Hino, Reiichiro Kuwahara, Keisuke Amano, Takashi Niizeki, Masahito Nakano, Ryoko Kuromatsu, Takuji Torimura
We report on a 62-year-old man with chronic hepatitis C who developed rapidly growing hepatocellular carcinoma (HCC) after achieving sustained virological response at post-treatment week 24 (SVR 24) by direct-acting antiviral (DAA) treatment. In 2008, he failed interferon therapy at 56 years of age. He received daclatasvir plus asunaprevir for 24 weeks after confirmation of no liver tumor by abdominal ultrasonography. He had no advanced liver fibrosis. Three months after initiation of DAA treatment, a liver tumor measuring 6 mm in diameter was detected by ultrasonography and confirmed with magnetic resonance imaging...
October 29, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29065631/association-patterns-of-ontological-features-signify-electronic-health-records-in-liver-cancer
#15
Lawrence W C Chan, S C Cesar Wong, Choo Chiap Chiau, Tak-Ming Chan, Liang Tao, Jinghan Feng, Keith W H Chiu
Electronic Health Record (EHR) system enables clinical decision support. In this study, a set of 112 abdominal computed tomography imaging examination reports, consisting of 59 cases of hepatocellular carcinoma (HCC) or liver metastases (so-called HCC group for simplicity) and 53 cases with no abnormality detected (NAD group), were collected from four hospitals in Hong Kong. We extracted terms related to liver cancer from the reports and mapped them to ontological features using Systematized Nomenclature of Medicine (SNOMED) Clinical Terms (CT)...
2017: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29042975/comparison-of-dwibs-t2-image-fusion-and-pet-ct-for-the-diagnosis-of-cancer-in-the-abdominal-cavity
#16
Minoru Tomizawa, Fuminobu Shinozaki, Yoshitaka Uchida, Katsuhiro Uchiyama, Satomi Tanaka, Takafumi Sunaoshi, Daisuke Kano, Eriko Sugiyama, Misaki Shite, Ryouta Haga, Yoshiya Fukamizu, Toshiyuki Fujita, Satoshi Kagayama, Rumiko Hasegawa, Yoshinori Shirai, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Fusion images of diffusion-weighted whole-body imaging with background body signal suppression and T2-weighted image (DWIBS/T2) demonstrate a strong signal for malignancies, with a high contrast against the surrounding tissues, and enable anatomical analysis. In the present study, DWIBS/T2 was compared with (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) for diagnosing cancer in the abdomen. Patient records, including imaging results of examination conducted between November 2012 and May 2014, were analyzed retrospectively...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29033422/a-case-of-hepatic-pseudolymphoma-with-an-occult-hepatitis-b-virus-infection
#17
Hideo Kunimoto, Daisuke Morihara, Shin-Ichiro Nakane, Takashi Tanaka, Keiji Yokoyama, Akira Anan, Yasuaki Takeyama, Makoto Irie, Satoshi Shakado, Tomoaki Noritomi, Morishige Takeshita, Kengo Yoshimitsu, Shotaro Sakisaka
A 49-year-old woman who was asymptomatic was found to have a small liver tumor on abdominal ultrasonography (US) at her annual health checkup. US revealed a hypoechoic, solid, mass measuring 17-mm in size in segment 6. The tumor markers associated with liver malignancy were negative. An infectious disease screen was negative for hepatitis B surface antigen, but positive for antibody to hepatitis B core antigen. Imaging studies using computed tomography (CT), magnetic resonance imaging (MRI), and CT angiography suggested a malignant liver tumor, such as hepatocellular carcinoma...
October 16, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29028279/liver-elastography-malignancy-prediction-lemp-score-for-noninvasive-characterization-of-focal-liver-lesions
#18
Ivica Grgurevic, Tomislav Bokun, Nermin N Salkic, Boris Brkljacic, Mirjana Vukelić-Markovic, Tajana Stoos-Veic, Gorana Aralica, Mislav Rakic, Tajana Filipec-Kanizaj, Annalisa Berzigotti
BACKGROUND & AIMS: To analyse elastographic characteristics of focal liver lesions (FLL)s and diagnostic performance of real-time two-dimensional shear-wave elastography (RT-2D-SWE) in order to differentiate benign and malignant FLLs. PATIENTS AND METHODS: Consecutive patients diagnosed with FLL by abdominal ultrasound (US) underwent RT-2D-SWE of FLL and non-infiltrated liver by intercostal approach over the right liver lobe. The nature of FLL was determined by diagnostic work-up, including at least one contrast-enhanced imaging modality (MDCT/MRI), check-up of target organs when metastatic disease was suspected and FLL biopsy in inconclusive cases...
October 13, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29023148/nonstandardized-terminology-to-describe-focal-liver-lesions-in-patients-at-risk-for-hepatocellular-carcinoma-implications-regarding-clinical-communication
#19
Michael T Corwin, Andrew Y Lee, Ghaneh Fananapazir, Thomas W Loehfelm, Souvik Sarkar, Claude B Sirlin
OBJECTIVE: The purpose of this study is to determine the correlation between malignancy risk of focal liver observations in patients at risk for hepatocellular carcinoma (HCC) implied by phrases used in nonstructured radiology reports with the risk inferred by hepatologists. MATERIALS AND METHODS: We performed a retrospective review of nonstructured radiology reports issued before Liver Imaging and Reporting Data System (LI-RADS) adoption from four-phase liver CT examinations of patients at risk for HCC...
October 12, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28989828/magnetic-resonance-imaging-of-primary-hepatic-malignancies-in-patients-with-and-without-chronic-liver-disease-a-pictorial-review
#20
REVIEW
Lauren F Alexander, Peter Harri, Brent Little, Courtney C Moreno, Pardeep K Mittal
Primary hepatic malignancies are less common than metastatic diseases, but a recognition of these lesions is important for diagnosis and treatment planning. Magnetic resonance imaging (MRI) provides the most imaging information to diagnose lesions noninvasively and to narrow differential diagnoses. This paper reviews the imaging findings of chronic liver disease and primary hepatic malignancies, including hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (CCA), epithelioid hemangioendothelioma, hepatic angiosarcoma, and primary hepatic lymphoma...
August 4, 2017: Curēus
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