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Abdominal imaging, hcc

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https://www.readbyqxmd.com/read/29042975/comparison-of-dwibs-t2-image-fusion-and-pet-ct-for-the-diagnosis-of-cancer-in-the-abdominal-cavity
#1
Minoru Tomizawa, Fuminobu Shinozaki, Yoshitaka Uchida, Katsuhiro Uchiyama, Satomi Tanaka, Takafumi Sunaoshi, Daisuke Kano, Eriko Sugiyama, Misaki Shite, Ryouta Haga, Yoshiya Fukamizu, Toshiyuki Fujita, Satoshi Kagayama, Rumiko Hasegawa, Yoshinori Shirai, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Fusion images of diffusion-weighted whole-body imaging with background body signal suppression and T2-weighted image (DWIBS/T2) demonstrate a strong signal for malignancies, with a high contrast against the surrounding tissues, and enable anatomical analysis. In the present study, DWIBS/T2 was compared with (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) for diagnosing cancer in the abdomen. Patient records, including imaging results of examination conducted between November 2012 and May 2014, were analyzed retrospectively...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29033422/a-case-of-hepatic-pseudolymphoma-with-an-occult-hepatitis-b-virus-infection
#2
Hideo Kunimoto, Daisuke Morihara, Shin-Ichiro Nakane, Takashi Tanaka, Keiji Yokoyama, Akira Anan, Yasuaki Takeyama, Makoto Irie, Satoshi Shakado, Tomoaki Noritomi, Morishige Takeshita, Kengo Yoshimitsu, Shotaro Sakisaka
A 49-year-old woman who was asymptomatic was found to have a small liver tumor on abdominal ultrasonography (US) at her annual health checkup. US revealed a hypoechoic, solid, mass measuring 17-mm in size in segment 6. The tumor markers associated with liver malignancy were negative. An infectious disease screen was negative for hepatitis B surface antigen, but positive for antibody to hepatitis B core antigen. Imaging studies using computed tomography (CT), magnetic resonance imaging (MRI), and CT angiography suggested a malignant liver tumor, such as hepatocellular carcinoma...
October 16, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29028279/liver-elastography-malignancy-prediction-lemp-score-for-noninvasive-characterization-of-focal-liver-lesions
#3
Ivica Grgurevic, Tomislav Bokun, Nermin N Salkic, Boris Brkljacic, Mirjana Vukelić-Markovic, Tajana Stoos-Veic, Gorana Aralica, Mislav Rakic, Tajana Filipec-Kanizaj, Annalisa Berzigotti
BACKGROUND & AIMS: To analyse elastographic characteristics of focal liver lesions (FLL)s and diagnostic performance of real-time two-dimensional shear-wave elastography (RT-2D-SWE) in order to differentiate benign and malignant FLLs. PATIENTS AND METHODS: Consecutive patients diagnosed with FLL by abdominal ultrasound (US) underwent RT-2D-SWE of FLL and non-infiltrated liver by intercostal approach over the right liver lobe. The nature of FLL was determined by diagnostic work-up, including at least one contrast-enhanced imaging modality (MDCT/MRI), check-up of target organs when metastatic disease was suspected and FLL biopsy in inconclusive cases...
October 13, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29023148/nonstandardized-terminology-to-describe-focal-liver-lesions-in-patients-at-risk-for-hepatocellular-carcinoma-implications-regarding-clinical-communication
#4
Michael T Corwin, Andrew Y Lee, Ghaneh Fananapazir, Thomas W Loehfelm, Souvik Sarkar, Claude B Sirlin
OBJECTIVE: The purpose of this study is to determine the correlation between malignancy risk of focal liver observations in patients at risk for hepatocellular carcinoma (HCC) implied by phrases used in nonstructured radiology reports with the risk inferred by hepatologists. MATERIALS AND METHODS: We performed a retrospective review of nonstructured radiology reports issued before Liver Imaging and Reporting Data System (LI-RADS) adoption from four-phase liver CT examinations of patients at risk for HCC...
October 12, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28989828/magnetic-resonance-imaging-of-primary-hepatic-malignancies-in-patients-with-and-without-chronic-liver-disease-a-pictorial-review
#5
REVIEW
Lauren F Alexander, Peter Harri, Brent Little, Courtney C Moreno, Pardeep K Mittal
Primary hepatic malignancies are less common than metastatic diseases, but a recognition of these lesions is important for diagnosis and treatment planning. Magnetic resonance imaging (MRI) provides the most imaging information to diagnose lesions noninvasively and to narrow differential diagnoses. This paper reviews the imaging findings of chronic liver disease and primary hepatic malignancies, including hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (CCA), epithelioid hemangioendothelioma, hepatic angiosarcoma, and primary hepatic lymphoma...
August 4, 2017: Curēus
https://www.readbyqxmd.com/read/28987671/dual-energy-spectral-ct-imaging-for-the-evaluation-of-small-hepatocellular-carcinoma-microvascular-invasion
#6
Chuang-Bo Yang, Shuang Zhang, Yong-Jun Jia, Yong Yu, Hai-Feng Duan, Xi-Rong Zhang, Guang-Ming Ma, Chenglong Ren, Nan Yu
OBJECTIVE: To study the clinical value of dual-energy spectral CT in the quantitative assessment of microvascular invasion of small hepatocellular carcinoma. METHODS: This study was approved by our ethics committee. 50 patients with small hepatocellular carcinoma who underwent contrast enhanced spectral CT in arterial phase (AP) and portal venous phase (VP) were enrolled. Tumour CT value and iodine concentration (IC) were measured from spectral CT images. The slope of spectral curve, normalized iodine concentration (NIC, to abdominal aorta) and ratio of IC difference between AP and VP (RICAP-VP: [RICAP-VP=(ICAP-ICVP)/ICAP]) were calculated...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28943929/contrast-enhanced-multiple-phase-imaging-features-of-intrahepatic-mass-forming-cholangiocarcinoma-and-hepatocellular-carcinoma-with-cirrhosis-a-comparative-study
#7
Ying Chen, Yao Pan, Ke-Ren Shen, Xiu-Liang Zhu, Chen-Ying Lu, Qing-Hai Li, Shu-Gao Han, Yan-Biao Fu, Xiu-Fang Xu, Ri-Sheng Yu
The intrahepatic mass-forming cholangiocarcinoma (IMCC) is frequently misdiagnosed as hepatocellular carcinoma (HCC) in patients with cirrhosis, by numerous radiologists and clinical doctors, which results in the incorrect therapeutic treatment. A retrospective case-control study was conducted, and the contrast-enhanced multiple-phase (CEMP) computed tomography (CT) and magnetic resonance imaging (MRI) findings of 22 pathologically confirmed IMCC patients and 22 HCC controls with underlying liver cirrhosis were analyzed at the present hospital, from January 2010 to December 2015...
October 2017: Oncology Letters
https://www.readbyqxmd.com/read/28920172/hepatocellular-carcinoma-screening-utilising-serum-alpha-fetoprotein-measurement-and-abdominal-ultrasound-is-more-effective-than-ultrasound-alone-in-patients-with-non-viral-cirrhosis
#8
Thomas Worland, Benjamin Harrison, Leighton Delmenico, Damian Dowling
PURPOSE: This study is aimed to determine the performance of alpha-fetoprotein (AFP) as part of hepatocellular carcinoma (HCC) screening in a non-viral cirrhosis population. METHODS: A retrospective audit was conducted of patients with non-viral cirrhosis over a 13 year period managed at a single centre. All patients were investigated routinely for evidence of viral hepatitis; patients with positive results were excluded from analysis. Cirrhosis was defined on basis of clinical, biochemical, and radiological investigations and examinations...
September 17, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28846946/surgical-treatment-for-the-excluded-bile-leakage-from-spiegel-lobe-after-right-hemihepatectomy-a-case-report
#9
Haruhi Fukuhisa, Masahiko Sakoda, Kiyokazu Hiwatashi, Satoshi Iino, Koji Minami, Motoyuki Hashiguchi, Yota Kawasaki, Hiroshi Kurahara, Yuko Mataki, Kosei Maemura, Hiroyuki Shinchi, Shinichi Ueno, Shoji Natsugoe
INRODUCTION: The treatments of excluded bile duct leakage after hepatectomy are not easy and various strategies have been reported, such as surgery, ethanol or fibrin glue injection, and portal vein embolization. PRESENTATION OF CASE: A 72-year-old man with a surgical history of laparoscopic ileocecal resection for diverticular bleeding was diagnosed as having hepatocellular carcinoma. Right hemihepatectomy was performed, and computed tomography examination on postoperative day 9 showed abdominal fluid collection in the right subphrenic space...
August 18, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28839428/from-diagnosis-to-treatment-of-hepatocellular-carcinoma-an-epidemic-problem-for-both-developed-and-developing-world
#10
REVIEW
Dimitrios Dimitroulis, Christos Damaskos, Serena Valsami, Spyridon Davakis, Nikolaos Garmpis, Eleftherios Spartalis, Antonios Athanasiou, Demetrios Moris, Stratigoula Sakellariou, Stylianos Kykalos, Gerasimos Tsourouflis, Anna Garmpi, Ioanna Delladetsima, Konstantinos Kontzoglou, Gregory Kouraklis
Hepatocellular carcinoma (HCC) is the most frequent primary liver malignancy and the third cause of cancer-related death in the Western Countries. The well-established causes of HCC are chronic liver infections such as hepatitis B virus or chronic hepatitis C virus, nonalcoholic fatty liver disease, consumption of aflatoxins and tobacco smocking. Clinical presentation varies widely; patients can be asymptomatic while symptomatology extends from right upper abdominal quadrant paint and weight loss to obstructive jaundice and lethargy...
August 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28791423/preliminary-trial-of-augmented-reality-performed-on-a-laparoscopic-left-hepatectomy
#11
Priyanka Phutane, Emmanuel Buc, Karine Poirot, Erol Ozgur, Denis Pezet, Adrien Bartoli, Bertrand Le Roy
BACKGROUND: Laparoscopic liver surgery is seldom performed, mainly because of the risk of hepatic vein bleeding or incomplete resection of the tumour. This risk may be reduced by means of an augmented reality guidance system (ARGS), which have the potential to aid one in finding the position of intrahepatic tumours and hepatic veins and thus in facilitating the oncological resection and in limiting the risk of operative bleeding. METHODS: We report the case of an 81-year-old man who was diagnosed with a hepatocellular carcinoma after an intraabdominal bleeding...
August 8, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28755196/the-qu%C3%A3-bec-ntbc-study
#12
Fernando Alvarez, Suzanne Atkinson, Manon Bouchard, Catherine Brunel-Guitton, Daniela Buhas, Jean-François Bussières, Josée Dubois, Daphna Fenyves, Paul Goodyer, Martyne Gosselin, Ugur Halac, Patrick Labbé, Rachel Laframboise, Bruno Maranda, Serge Melançon, Aicha Merouani, Grant A Mitchell, John Mitchell, Guy Parizeault, Luc Pelletier, Véronique Phan, Jean-François Turcotte
In this chapter we describe the current Quebec NTBC Study protocol. Quebec's unique characteristics have influenced the development of the protocol, including a high prevalence of hepatorenal tyrosinemia (HT1), universal newborn screening for HT1, availability of treatment with nitisinone (NTBC) and special diet, a large territory, where HT1 treatment is coordinated by a small number of centers. Screened newborns are seen within 3 weeks of birth. Patients with liver dysfunction (prolonged prothrombin time and/or international normalized ratio (INR) provide sensitive, rapidly available indicators) are treated by NTBC and special diet...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28722597/occult-amoebic-liver-abscess-as-cause-of-extensive-inferior-vena-cava-and-hepatic-vein-thrombosis
#13
Leslie Martin, Nishigandha Burute, Ehsan Haider, Pablo E Serrano, Timothy O'Shea, Deborah Siegal
The most common extraintestinal complication of Entamoeba histolytica is amoebic liver abscess (ALA). Hepatic vein and inferior vena cava (IVC) thrombosis are rare but well-documented complications of ALA, typically attributed to mechanical compression and inflammation associated with a large abscess. We present a case of a previously healthy 43-year-old Canadian man presenting with constitutional symptoms and right upper quadrant abdominal pain. He was found to have thrombophlebitis of the IVC, accessory right hepatic vein, and bilateral iliac veins...
July 3, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28689934/single-center-comparison-of-overall-survival-and-toxicities-in-patients-with-infiltrative-hepatocellular-carcinoma-treated-with-yttrium-90-radioembolization-or-drug-eluting-embolic-transarterial-chemoembolization
#14
Joseph L McDevitt, Ali Alian, Baljendra Kapoor, Stacy Bennett, Amanjit Gill, Abraham Levitin, Mark Sands, K V Narayanan Menon, Federico N Aucejo, Bassam Estfan, Anil K Pillai, Sanjeeva P Kalva, Gordon McLennan
PURPOSE: To compare overall survival and toxicities after yttrium-90 ((90)Y) radioembolization and chemoembolization with drug-eluting embolics (DEE) in patients with infiltrative hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Retrospective review of 50 patients with infiltrative HCC without main portal vein invasion who were treated with (90)Y radioembolization (n = 26) or DEE chemoembolization (n = 24) between March 2007 and August 2012 was completed...
October 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28624924/evaluation-of-hepatic-fibrosis-a-review-from-the-society-of-abdominal-radiology-disease-focus-panel
#15
REVIEW
Jeanne M Horowitz, Sudhakar K Venkatesh, Richard L Ehman, Kartik Jhaveri, Patrick Kamath, Michael A Ohliger, Anthony E Samir, Alvin C Silva, Bachir Taouli, Michael S Torbenson, Michael L Wells, Benjamin Yeh, Frank H Miller
Hepatic fibrosis is potentially reversible; however early diagnosis is necessary for treatment in order to halt progression to cirrhosis and development of complications including portal hypertension and hepatocellular carcinoma. Morphologic signs of cirrhosis on ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) alone are unreliable and are seen with more advanced disease. Newer imaging techniques to diagnose liver fibrosis are reliable and accurate, and include magnetic resonance elastography and US elastography (one-dimensional transient elastography and point shear wave elastography or acoustic radiation force impulse imaging)...
August 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28602501/abdominal-imaging-surveillance-in-adult-patients-after-fontan-procedure-risk-of-chronic-liver-disease-and-hepatocellular-carcinoma
#16
Sadhna B Nandwana, Babatunde Olaiya, Kelly Cox, Anurag Sahu, Pardeep Mittal
PURPOSE: To assess the prevalence of chronic liver disease (CLD) and hepatocellular carcinoma (HCC) in adult patients who had surveillance imaging after Fontan procedure. METHODS: Institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study evaluated electronic medical records including radiology reports and clinical notes for adult patients after Fontan procedure between January 1993 and January 2016. Abdominal ultrasound, computed tomography, and magnetic resonance imaging reports were reviewed for changes of CLD and HCC...
April 11, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28587434/diagnostic-accuracy-of-diffusion-weighted-whole-body-imaging-with-background-body-signal-suppression-t2-weighted-image-fusion-for-the-detection-of-abdominal-solid-cancer
#17
Minoru Tomizawa, Fuminobu Shinozaki, Kazunori Fugo, Satomi Tanaka, Takafumi Sunaoshi, Daisuke Kano, Eriko Sugiyama, Misaki Shite, Ryouta Haga, Yoshiya Fukamizu, Toshiyuki Fujita, Satoshi Kagayama, Rumiko Hasegawa, Akira Togawa, Yoshinori Shirai, Noboru Ichiki, Yuji Oshima, Naoto Koike, Yasuko Toshimitsu, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Takashi Kishimoto, Naoki Ishige
Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) images show significant contrast for cancer tissues against non-cancerous tissues. Fusion of a DWIBS and a T2-weighted image (DWIBS/T2) can be used to obtain functional, as well as anatomic, information. In the present study, the performance of DWIBS/T2 in the diagnosis of abdominal solid cancer was evaluated. The records of 14 patients were retrospectively analyzed [5 patients with hepatocellular carcinoma (HCC), 4 with metastatic liver cancer, 3 with pancreatic cancer, 1 with renal cellular carcinoma and 1 with malignant lymphoma of the para-aortic lymph node]...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28583643/utility-of-t1-weighted-mri-as-a-predictor-of-liver-lesion-visibility-on-ultrasound-a-clinical-tool-to-determine-feasibility-of-ultrasound-guided-percutaneous-interventions
#18
Timothy L Miao, Ania Z Kielar, Rebecca M Hibbert, Nicola Schieda
PURPOSE: To determine the utility of fat-suppressed T1-weighted gradient recalled echo (FS-T1W-GRE) MRI to predict visibility of focal liver lesions (FLL) on abdominal ultrasound (US). MATERIALS AND METHODS: With IRB approval, between 2010 and 2013, 109 patients (28.4% females, age 66.9±10.9years) with 177 FLL (hepatocellular carcinoma=132, metastases=44, other=1) underwent MRI and prospective, radiologist-performed treatment-planning US (to determine eligibility for US-guided ablation)...
May 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28531870/an-unusual-case-of-jaundice-biliary-tumor-thrombus-in-fibrolamellar-hepatocellular-carcinoma
#19
Jairo A Espinosa, Alex Merlo, Mohamed-Omar Arafeh, Gitonga Munene
BACKGROUND: Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare and unique variant of hepatocellular carcinoma (HCC) whose presentation remains inadequately described. We present a resectable case of FL-HCC which involved tumor thrombus of the common bile duct. PRESENTATION: A 27 year-old male presenting with jaundice, abdominal pain, vomiting, hepatic dysfunction and hyperbilirubinemia was found to have a large liver mass and lymphadenopathy on preoperative imaging...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28491877/nodular-regenerative-hyperplasia-a-case-of-rare-prognosis
#20
Mindy Lee, Manhal Izzy, Ashwin Akki, Kathryn Tanaka, Harmit Kalia
Introduction: Nodular regenerative hyperplasia (NRH) is a known etiology of noncirrhotic portal hypertension. Cases of biopsy-proven NRH in human immunodeficiency virus (HIV)-positive patients have been described. While these patients often have normal synthetic liver function, several reports described disease progression to liver failure. Case: We here present a 26-year-old woman with history of congenital HIV on antiretroviral therapy complicated by Pneumocystis carinii pneumonia at age 14. CD4 counts have been >300 with undetectable viral load...
January 2017: Journal of Investigative Medicine High Impact Case Reports
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