keyword
https://read.qxmd.com/read/38523943/the-role-of-clinical-audits-in-advancing-quality-and-safety-in-healthcare-services-a-multiproject-analysis-from-a-jordanian-hospital
#1
JOURNAL ARTICLE
Mohammad Abu-Jeyyab, Mohammad Al-Jafari, Mostafa H El Din Moawad, Sallam Alrosan, Mohammad Al Mse'adeen
Introduction Clinical audits have become essential instruments for evaluating and improving the standard of patient care in healthcare services. While individual clinical audits focus on particular aspects of care, multiple clinical audits across various domains, specialties, or departments provide a more comprehensive understanding of clinical practice and encourage systemic improvements. Methodology This study employed a mixed-methods approach to review and assess various clinical audits and quality improvement initiatives conducted at Al-Karak Governmental Hospital in southern Jordan...
February 2024: Curēus
https://read.qxmd.com/read/38518602/the-effects-of-fc-fusion-protein-glucagon-like-peptide-1-and-glucagon-dual-receptor-agonist-with-different-receptor-selectivity-in-vivo-studies
#2
JOURNAL ARTICLE
Peng Jiang, Ying Zeng, Wen Yang, Lijia Li, Linjun Zhou, Lin Xiao, Yong Li, Baohua Gu, Xiaoping Li, Jing Li, Wenjia Li, Linfeng Guo
BACKGROUND: Glucagon-like peptide-1 (GLP-1)/glucagon (GCG) dual receptor agonists with different receptor selectivity are under investigation and have shown significant improvement in both weight loss and glycemic control, but the optimal potency ratio between the two receptors to balance efficacy and safety remains unclear. EXPERIMENTAL APPROACH: We designed and constructed several dual receptor agonists with different receptor potency ratios using Fc fusion protein technology...
March 21, 2024: Biomedicine & Pharmacotherapy
https://read.qxmd.com/read/38512447/efficacy-and-safety-of-tirzepatide-in-overweight-and-obese-adult-patients-with-type-1-diabetes
#3
JOURNAL ARTICLE
Satish K Garg, Halis Kaan Akturk, Gurleen Kaur, Christie Beatson, Janet Snell-Bergeon
INTRODUCTION & OBJECTIVE: Most patients with type 1 diabetes (T1D) in the USA are overweight (OW) or obese (OB), contributing to insulin resistance and suboptimal glucose control. The primary FDA approved treatment for T1D is insulin, which may adversely affect weight. Tirzepatide is approved for managing type 2 diabetes, improves glucose control, facilitates weight loss, and improves CVD outcomes. We assessed the use of tirzepatide in OW/OB subjects with T1D. METHODS: This was a retrospective single-center, real-world study in 62 OW/OB adult patients with T1D who were prescribed tirzepatide (treated group) and followed for one year...
March 21, 2024: Diabetes Technology & Therapeutics
https://read.qxmd.com/read/38186742/dataset-of-amplicon-metagenomic-assessment-of-barley-rhizosphere-bacteria-under-different-fertilization-regimes
#4
JOURNAL ARTICLE
Olubukola Oluranti Babalola, Ben Jesuorsemwen Enagbonma
The metagenomic dataset profiled in this research is built on bacterial 16S rRNA gene amplicon of DNA mined from barley rhizosphere under chemical (CB) and organic (OB) fertilization. Amplicon-based sequencing was prepared by the Illumina platform, and the raw sequence dataset was examined using Metagenomic Rast Server (MG-RAST). The metagenome comprised sixteen samples that include CB1 (494,583 bp), CB2 (586,532 bp), CB3 (706,685 bp), CB4 (574,606 bp), CB5 (395,460 bp), CB6 (520,822 bp), CB7 (511,729 bp), CB8 (548,074 bp), OB1 (642,794 bp), OB2 (513,767 bp), OB3 (461,293 bp), OB4 (498,241 bp), OB5 (689,497 bp), OB6 (423,436 bp), OB7 (478,657 bp) and OB8 (279,186 bp)...
February 2024: Data in Brief
https://read.qxmd.com/read/38128865/the-obstetrical-emergency-department-need-rationale-and-guide-to-implementation
#5
JOURNAL ARTICLE
Sarah L Bradley, Vasiliki Tatsis, Kristen Wolfe, Trina Pagano, Andrea Tucker, Andrea Bartlett, Tyler Katz
The past 2 decades have seen dramatic growth in the number of obstetrics and gynecology hospitalists, and many hospitals have created obstetrical-specific emergency departments. The goals of an obstetrics emergency department are to provide safe and efficient care to the pregnant dyad and postpartum patient, while generating revenue for emergency services provided. In an obstetrics emergency department, all patients must be evaluated in person by a licensed practitioner, whereas historically they may have been evaluated in person by nursing staff or a trainee...
December 19, 2023: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38127141/efficacy-and-safety-of-v-loc-%C3%A2-barbed-sutures-versus-conventional-suture-techniques-in-gynecological-surgery-a-systematic-review-and-meta-analysis
#6
REVIEW
Juliane Hafermann, Ubong Silas, Rhodri Saunders
PURPOSE: One of the most challenging tasks in laparoscopic gynecological surgeries is suturing. Knotless barbed sutures are intended to enable faster suturing and hemostasis. We carried out a meta-analysis to compare the efficacy and safety of V-Loc™ barbed sutures (VBS) with conventional sutures (CS) in gynecological surgeries. METHODS: We systematically searched PubMed and EMBASE for studies published between 2010 and September 2021 comparing VBS to CS for OB/GYN procedures...
December 21, 2023: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38117846/exploring-patients-experiences-with-telehealth-in-obstetrics-care-during-the-covid-19-pandemic-a-qualitative-study
#7
JOURNAL ARTICLE
Mohammad Alkawaldeh, Asma Alkhawaldeh, Tracy Yeboah
AIM: The aim of this study was to evaluate patients' experiences with telehealth provision of obstetrics and gynecology care during the COVID-19 pandemic qualitatively. DESIGN AND SETTING: In this study, a qualitative research design, namely descriptive phenomenology, was employed. Participants were recruited from the OB department at UMass Memorial Medical center in Worcester, MA, between 6/2020 and 7/2020. METHODS: Between June 2020 and July 2020, in-depth interviews were conducted with 18 women receiving care at the Obstetrics and Maternal and Fetal Medicine clinics...
2023: PloS One
https://read.qxmd.com/read/37967721/assessing-pharmacist-and-clinician-perspectives-on-pharmacist-prescribed-hormonal-contraceptives
#8
JOURNAL ARTICLE
Audrey Whalen, Jeffrey Bratberg, Lisa Cohen, Kelly Orr, Virginia Lemay
BACKGROUND: After the Dobbs, et al ruling in June 2022 by the US Supreme Court eliminated the federal right to abortion care, concerns about access to reproductive health have been elevated. Barriers to contraception use consist of knowledge deficits, unfavorable legal rulings, cost and insurance coverage, unnecessary medical practices and health care inequities. Pharmacists are the most accessible health care providers who are positioned to mitigate these barriers and expand reproductive health access through scope of practice expansion...
November 13, 2023: Journal of the American Pharmacists Association: JAPhA
https://read.qxmd.com/read/37884178/navigating-a-plethora-of-progesterone-receptors-comments-on-the-safety-risk-of-progesterone-supplementation-in-women-with-a-history-of-breast-cancer-or-at-high-risk-for-developing-breast-cancer
#9
JOURNAL ARTICLE
Caroline H Diep, Laura J Mauro, Carol A Lange
Progesterone and progestin agonists are potent steroid hormones. There are at least three major types of progesterone receptor (PR) families that interact with and respond to progesterone or progestin ligands. These receptors include ligand-activated transcription factor isoforms (PR-A and PR-B) encoded by the PGR gene, often termed classical or nuclear progesterone receptor (nPR), membrane-spanning progesterone receptor membrane component proteins known as PGRMC1/2, and a large family of progestin/adipoQ receptors or PAQRs (also called membrane PRs or mPRs)...
October 24, 2023: Steroids
https://read.qxmd.com/read/37837678/optimization-and-characterization-of-taro-starch-nisin-and-sodium-alginate-based-biodegradable-films-antimicrobial-effect-in-chicken-meat
#10
JOURNAL ARTICLE
Monserrat Guevara Carrión, María Antonieta Ríos Corripio, Juan Valente Hidalgo Contreras, Marcela Rangel Marrón, Gema Morales Olán, Aleida Selene Hernández Cázares
Biodegradable films based on polymers from renewable resources have become a feasible technology to preserve the quality (texture, color, flavor) and safety of food. The addition of antimicrobial agents to films can prevent the growth of pathogenic microorganisms that affect meat and poultry products. In this study, a biodegradable film with sodium alginate (SA), taro starch (MS), and nisin (Nis) was optimized to have high tensile strength (TS), breaking force (BF), and a low water vapor permeability (WVP) using a Box-Behnken response surface design, and its antimicrobial effect was evaluated in relation to its use as a packaging material for chicken meat...
September 12, 2023: Poultry Science
https://read.qxmd.com/read/37529758/legislation-has-changed-but-issues-remain-provider-perceptions-of-caring-for-people-who-use-cannabis-during-pregnancy-in-safety-net-health-settings-a-qualitative-pilot-study
#11
JOURNAL ARTICLE
Rachel Carmen Ceasar, Erin Gould, Julia Stal, Jen Laughter, Michelle Tran, Shirlene D Wang, Jordan Granacki, Ryan S Ziltzer, Jasmeen Joy Santos
OBJECTIVE: To identify perceptions of cannabis use and risk among maternal health providers who provide care for people who use cannabis during pregnancy in safety-net health settings. METHODS: Using qualitative, constructivist ground theory methods, we conducted semistructured remote interviews with 10 providers (2 midwives, 6 OB/GYN physicians, and 2 OB/GYN residents) in Southern California, United States, between March 15, 2022, and April 6, 2022. We selected participants through selective sampling using a convenience sample and snowball approach...
2023: Women's health reports
https://read.qxmd.com/read/37494577/mirabegron-and-anticholinergics-in-the-treatment-of-overactive-bladder-syndrome-a-meta-analysis
#12
JOURNAL ARTICLE
Luisa Gracio Ferreira Sartori, Bruno Monteiro Nunes, Daniela Farah, Leticia Maria de Oliveira, Claudia Cristina Takano Novoa, Marair Gracio Ferreira Sartori, Marcelo Cunio Machado Fonseca
OBJECTIVE:  To compare the use of mirabegron with anticholinergics drugs for the treatment of overactive bladder (OB). DATA SOURCE:  Systematic searches were conducted in EMBASE, PUBMED, Cochrane, and LILACS databases from inception to September 2021. We included RCTs, women with clinically proven OB symptoms, studies that compared mirabegron to antimuscarinic drugs, and that evaluated the efficacy, safety or adherence. DATA COLLECTION:  RevMan 5...
June 2023: Revista Brasileira de Ginecologia e Obstetrícia
https://read.qxmd.com/read/37432173/hmc-ameliorates-hyperglycemia-via-acting-pi3k-akt-pathway-and-improving-foxo1-pathway-in-ob-ob-mice
#13
JOURNAL ARTICLE
Jeong Yoo, Jae Eun Park, Ji Sook Han
Type 2 diabetes is a disease characterized by hyperglycemia and is a growing health problem worldwide. Since many known diabetes drugs are side effects, it is necessary to develop natural substances with guaranteed safety. HM-chromanone isolated from Portulaca oleracea L. is a homoisoflavonoid compound. We investigated the effects of HM-chromanone on hyperglycemia and its mechanism in C57BL/6J ob/ob mice. C57BL/6J-Jms Slc mice were used as the control group, and C57BL/6J-ob/ob mice were divided into three groups: ob/ob (control), metformin (Met; positive control), and HM-chromanone (HMC)...
April 22, 2023: Nutrients
https://read.qxmd.com/read/37417642/orelabrutinib-versus-ibrutinib-for-patients-with-refractory-relapsed-primary-central-nervous-system-lymphoma-an-efficacy-and-safety-analysis
#14
JOURNAL ARTICLE
Lijiao Qiao, Quanxia Liu, Chunzhou Huang
Ibrutinib is reported effective in the management of refractory/relapsed primary central nervous system lymphoma but it has adverse effects. Orelabrutinib has received its first approval for the treatment of refractory/relapsed lymphoma either alone or with chemotherapy in China. The objectives of the retrospective study were to evaluate the efficacy and safety of treatment a combination of orelabrutinib (150 mg/day) and rituximab (250 mg/m 2 per week), versus orelabrutinib alone (100 mg twice a day) and ibrutinib alone (560 mg/day) among patients with refractory/relapsed primary central nervous system lymphoma...
July 7, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37339646/clinical-simulation-in-the-training-of-obstetrics-and-gynecology-resident-from-the-perspective-of-medical-residency-programs
#15
JOURNAL ARTICLE
Simone Pereira Vidotti, Nildo Alves Batista
OBJECTIVE:  This study analyzes the role of clinical simulation in internal medical residency programs (IMRP) in Obstetrics and Gynecology (OB/GYN), attributed by the supervisors, in the training of residents in the city of São Paulo (SP). METHODS:  Cross-sectional descriptive, qualitative, and exploratory approach. Semi-structured interviews were performed with ten supervisors of Medical Residency programs in Obstetrics and Gynecology. Interviews were analyzed by means of content analysis under the thematic modality, starting with the core the role of clinical simulation in Obstetrics and Gynecology Medical Residency Programs...
May 2023: Revista Brasileira de Ginecologia e Obstetrícia
https://read.qxmd.com/read/37298291/targeting-the-inflammatory-hallmarks-of-obesity-associated-osteoarthritis-towards-nutraceutical-oriented-preventive-and-complementary-therapeutic-strategies-based-on-n-3-polyunsaturated-fatty-acids
#16
REVIEW
Laura Gambari, Antonella Cellamare, Francesco Grassi, Brunella Grigolo, Alessandro Panciera, Alberto Ruffilli, Cesare Faldini, Giovanna Desando
Obesity (Ob), which has dramatically increased in the last decade, is one of the main risk factors that contribute to the incidence and progression of osteoarthritis (OA). Targeting the characteristics of obesity-associated osteoarthritis (ObOA) may offer new chances for precision medicine strategies in this patient cohort. First, this review outlines how the medical perspective of ObOA has shifted from a focus on biomechanics to the significant contribution of inflammation, mainly mediated by changes in the adipose tissue metabolism through the release of adipokines and the modification of fatty acid (FA) compositions in joint tissues...
May 26, 2023: International Journal of Molecular Sciences
https://read.qxmd.com/read/37272133/assessment-of-young-mothers-oral-hygiene-practices-during-pregnancy-and-their-knowledge-of-children-s-oral-health-in-northern-greece
#17
JOURNAL ARTICLE
Efthimia Chalvatzoglou, Filomeni Anagnostou, Konstantinos Arapostathis, Vasiliki Boka, Aristidis Arhakis
AIM: The aim of the study was to assess maternal knowledge about oral health practices for children along with oral hygiene perceptions of mothers during pregnancy in the city of Thessaloniki, Greece. MATERIALS AND METHODS: This cross-sectional study was conducted among 300 newly delivered mothers who were admitted to the obstetrician/gynecological (OB/GYN) University Clinic in Thessaloniki, Greece, to give birth. A three-part, self-reported, 40-item questionnaire was designed, collecting socioeconomic data, perceptions, and practices regarding maternal oral hygiene during pregnancy and their knowledge in relation to children's oral health...
March 1, 2023: Journal of Contemporary Dental Practice
https://read.qxmd.com/read/37243999/how-do-french-obstetrician-gynaecologists-perceive-their-quality-of-life-a-national-survey
#18
MULTICENTER STUDY
Margaux Merlier, Louise Ghesquière, Cyril Huissoud, E Drumez, Oliver Morel, Charles Garabedian
OBJECTIVE: Obstetrics is a constraining specialty due to heavy workloads and repeated stressful situations. French maternity wards are facing many difficulties to recruit, as a consequence of the conversion of a significant number of Obstetrician-Gynecologists (OB-GYNs) to exclusive daily private practice. The aim of this study was to evaluate the quality of life (QOL) of OB-GYNs in order to identify burnout risk factors, develop prevention strategies and therefore ensure patient safety...
July 2023: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/37109066/physicians-perspectives-on-a-multi-dimensional-model-for-the-roles-of-electronic-health-records-in-approaching-a-proper-differential-diagnosis
#19
JOURNAL ARTICLE
Abdullah Alanazi, Amal Almutib, Bakheet Aldosari
Many healthcare organizations have adopted Electronic Health Records (EHRs) to improve the quality of care and help physicians make proper clinical decisions. The vital roles of EHRs can support the accuracy of diagnosis, suggest, and rationalize the provided care to patients. This study aims to understand the roles of EHRs in approaching proper differential diagnosis and optimizing patient safety. This study utilized a cross-sectional survey-based descriptive research design to assess physicians' perceptions of the roles of EHRs on diagnosis quality and safety...
April 19, 2023: Journal of Personalized Medicine
https://read.qxmd.com/read/37019478/community-support-persons-and-mitigating-obstetric-racism-during-childbirth
#20
JOURNAL ARTICLE
Elle Lett, Marie-Fatima Hyacinthe, Dána-Ain Davis, Karen A Scott
PURPOSE: We undertook a study to assess whether presence of community support persons (CSPs), with no hospital affiliation or alignment, mitigates acts of obstetric racism during hospitalization for labor, birth, and immediate postpartum care. METHODS: We conducted a cross-sectional cohort study, measuring 3 domains of obstetric racism as defined for, by, and with Black birthing people: humanity (violation of safety and accountability, autonomy, communication and information exchange, and empathy); kinship (denial or disruption of community and familial bonds that support Black birthing people); and racism in the form of anti-Black racism and misogynoir (weaponization of societal stereotypes and scripts in service provision that reproduce gendered anti-Black racism in the hospital)...
April 5, 2023: Annals of Family Medicine
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