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https://www.readbyqxmd.com/read/27914228/osteoblastic-extraosseous-osteosarcoma-of-the-neck
#1
Andro Košec, Majda Vučić, Vladimir Bedeković, Mirko Ivkić
Extraosseous osteosarcoma as a primary tumor of the neck is exceedingly rare, with only a few cases reported to date. The most appropriate therapy is still under investigation. We report a case of an aggressive, right-sided, advanced-stage extraosseous osteosarcoma in a female patient. A 48-year-old woman presented with a right-sided infra-parotid mass encompassing neck regions II and III, measuring over 6 cm in craniocaudal diameter. She was initially treated by wide surgical resection. The definitive histopathologic diagnosis was osteoblastic extraosseous osteosarcoma...
November 16, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27898191/reirradiation-with-intensity-modulated-radiotherapy-for-locally-recurrent-t3-to-t4-nasopharyngeal-carcinoma
#2
Oscar S H Chan, Henry C K Sze, Michael C H Lee, Lucy L K Chan, Amy T Y Chang, Sarah W M Lee, Wai Man Hung, Anne W M Lee, Wai Tong Ng
BACKGROUND: The purpose of this study was to assess the efficacy and toxicities of reirradiation using intensity-modulated radiotherapy (IMRT) in patients with locally advanced recurrent nasopharyngeal carcinoma (NPC). METHODS: Thirty-eight patients with consecutive rT3 to rT4 NPC treated between 2005 and 2013 were retrospectively analyzed. RESULTS: The 3-year overall survival (OS), progression-free survival (PFS), and local control rate were 47...
November 29, 2016: Head & Neck
https://www.readbyqxmd.com/read/27893327/radiation-therapy-for-glioblastoma-american-society-of-clinical-oncology-clinical-practice-guideline-endorsement-of-the-american-society-for-radiation-oncology-guideline
#3
Erik P Sulman, Nofisat Ismaila, Terri S Armstrong, Christina Tsien, Tracy T Batchelor, Tim Cloughesy, Evanthia Galanis, Mark Gilbert, Vinai Gondi, Mary Lovely, Minesh Mehta, Matthew P Mumber, Andrew Sloan, Susan M Chang
Purpose The American Society for Radiation Oncology (ASTRO) produced an evidence-based guideline on radiation therapy for glioblastoma. Because of its relevance to the ASCO membership, ASCO reviewed the guideline and applied a set of procedures and policies used to critically examine guidelines developed by other organizations. Methods The ASTRO guideline on radiation therapy for glioblastoma was reviewed for developmental rigor by methodologists. An ASCO endorsement panel updated the literature search and reviewed the content and recommendations...
November 28, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27891442/a-retrospective-evaluation-of-clinical-profile-of-second-primary-head-and-neck-cancer
#4
Paramjeet Kaur, Nupur Bansal, J Vijaya Kumar, Anil Khurana, Ashok Chauhan
INTRODUCTION: Incidence of Second Primary Malignancy (SPM) after successful treatment of primary is increasing and may cause the problem for optimal treatment. AIM: This study was conducted retrospectively to analyse incidence, disease free survival between malignancies, pattern of treatment and outcome. MATERIALS AND METHODS: Sixteen out of 22 patients of previously treated cases of head and neck cancer those develop SPM of head and neck region managed over a period of January 2012 to December 2015 in Department of Radiotherapy-II, Pt...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27843507/effect-of-led-and-argon-laser-on-degree-of-conversion-and-temperature-rise-of-hybrid-and-low-shrinkage-composite-resins
#5
Ayob Pahlevan, Masumeh Hasani Tabatabaei, Sakineh Arami, Sara Valizadeh
OBJECTIVES: Different light curing units are used for polymerization of composite resins. The aim of this study was to evaluate the degree of conversion (DC) and temperature rise in hybrid and low shrinkage composite resins cured by LED and Argon Laser curing lights. MATERIALS AND METHODS: DC was measured using FTIR spectroscopy. For measuring temperature rise, composite resin samples were placed in Teflon molds and cured from the top. The thermocouple under samples recorded the temperature rise...
2016: Open Dentistry Journal
https://www.readbyqxmd.com/read/27826034/multi-institutional-prospective-study-of-reirradiation-with-proton-beam-radiotherapy-for-locoregionally-recurrent-non-small-cell-lung-cancer
#6
Hann-Hsiang Chao, Abigail T Berman, Charles B Simone, Christine Ciunci, Peter Gabriel, Haibo Lin, Stefan Both, Corey Langer, Kristi Lelionis, Ramesh Rengan, Stephen M Hahn, Kiran Prabhu, Marcio Fagundes, William Hartsell, Rosemarie Mick, John P Plastaras
PURPOSE: The management of recurrent non-small cell lung cancer (NSCLC) in the setting of prior radiation therapy is challenging. Proton radiotherapy (PRT) is ideally suited to minimize toxicity to previously irradiated organs. We report the safety/feasibility of PRT for NSCLC reirradiation in a prospective multi-institutional study. MATERIALS AND METHODS: Between 10/2010-12/2015, 57 patients with recurrent NSCLC in/near their prior radiation field were treated at three proton centers...
November 4, 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27822060/patterns-of-failure-and-survival-in-patients-with-nasopharyngeal-carcinoma-treated-with-intensity-modulated-radiation-therapy-in-saudi-arabia
#7
Ahmed Marzouk Maklad, Yasser Bayoumi, Mohamed Abdalazez Senosy Hassan, AbuSaleh A Elawadi, Hussain AlHussain, Ashraf Elyamany, Saleh F Aldhahri, Khalid Hussain Al-Qahtani, Mubarak AlQahtani, Mutahir A Tunio
BACKGROUND: We aimed to investigate the patterns of failure (locoregional and distant metastasis), associated factors, and treatment outcomes in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy (IMRT) combined with chemotherapy. PATIENTS AND METHODS: From April 2006 to December 2011, 68 nasopharyngeal carcinoma patients were treated with IMRT and chemotherapy at our hospital. Median radiation doses delivered to gross tumor volume and positive neck nodes were 66-70 Gy, 63 Gy to clinical target volume, and 50...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27788954/reirradiation-of-recurrent-and-second-primary-head-and-neck-cancer-with-proton-therapy
#8
Mark W McDonald, Omid Zolali-Meybodi, Stephen J Lehnert, Neil C Estabrook, Yuan Liu, Aaron A Cohen-Gadol, Michael G Moore
PURPOSE: To report the clinical outcomes of head and neck reirradiation with proton therapy. METHODS AND MATERIALS: From 2004 to 2014, 61 patients received curative-intent proton reirradiation, primarily for disease involving skull base structures, at a median of 23 months from the most recent previous course of radiation. Most had squamous cell (52.5%) or adenoid cystic (16.4%) carcinoma. Salvage surgery before reirradiation was undertaken in 47.5%. Gross residual disease was present in 70...
November 15, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27755060/hyperfractionated-accelerated-reirradiation-for-patients-with-recurrent-anal-cancer-previously-treated-with-definitive-chemoradiation
#9
Eleanor M Osborne, Cathy Eng, John M Skibber, Miguel A Rodriguez-Bigas, George J Chang, Yi-Qian Nancy You, Brian K Bednarski, Bruce D Minsky, Marc E Delclos, Eugene Koay, Sunil Krishnan, Christopher H Crane, Prajnan Das
OBJECTIVES: Although chemoradiation is the standard of care for anal cancer, limited data exist regarding pelvic reirradiation (re-RT) for recurrent disease. We investigated toxicity and outcomes in patients who received prior pelvic radiation therapy (RT), and subsequently underwent hyperfractionated accelerated re-RT to the pelvis for recurrent anal cancer. MATERIALS AND METHODS: We reviewed records of 10 patients with recurrent anal squamous cell carcinoma who previously received pelvic RT to at least 30 Gy as a component of their chemoradiation and underwent re-RT in 1...
October 17, 2016: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27745912/perioperative-high-dose-rate-brachytherapy-phdrb-in-previously-irradiated-head-and-neck-cancer-results-of-a-phase-i-ii-reirradiation-study
#10
Maria Isabel Martínez-Fernández, Juan Alcalde, Mauricio Cambeiro, German Valtueña Peydró, Rafael Martínez-Monge
BACKGROUND AND PURPOSE: This study was undertaken to determine the feasibility of salvage surgery and PHDRB in patients with previously irradiated, recurrent head and neck cancer or second primary tumors arising in a previously irradiated field. METHODS AND MATERIALS: Sixty-three patients were treated with surgical resection and PHDRB. The PHDRB dose was 4Gy b.i.d.×8 (32Gy) for R0 resections and 4Gy b.i.d.×10 (40Gy) for R1 resections, respectively. Further external beam radiotherapy or chemotherapy was not given...
October 13, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27717335/with-or-without-reirradiation-in-advanced-local-recurrent-nasopharyngeal-carcinoma-a-case-control-study
#11
Li-Ting Liu, Qiu-Yan Chen, Lin-Quan Tang, Lu Zhang, Shan-Shan Guo, Ling Guo, Hao-Yuan Mo, Chong Zhao, Xiang Guo, Ming-Yuan Chen, Chao-Nan Qian, Mu-Sheng Zeng, Ming-Huang Hong, Jian-Yong Shao, Ying Sun, Jun Ma, Hai-Qiang Mai
BACKGROUND: The study aimed to evaluate the long-term outcome in patients with advanced local recurrent nasopharyngeal carcinoma (NPC) treated with or without reirradiation. METHODS: A total of 44 patients treated without reirradiation (non-RT + chemotherapy) were matched with 44 patients treated with reirradiation (re-RT+/-chemtherapy) by age, sex, Karnosky performance score (KPS), rT stage, rN stage, and time interval between initial radiation and recurrence (TI)...
October 7, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27707842/brain-metastasis-reirradiation-in-patients-with-advanced-breast-cancer
#12
Zhou Huang, Bing Sun, Ge Shen, Lei Cha, Xiangying Meng, Junliang Wang, Zhenshan Zhou, Shikai Wu
The outcome of recurrent brain metastasis is dismal. This study aims to assess the clinical outcomes and toxicity of reirradiation as a salvage treatment for progressive brain metastasis in patients with advanced breast cancer. Between July 2005 and September 2014, the medical records of 56 patients with brain metastasis from breast cancer were retrospectively reviewed. Of these patients, 39 received whole-brain radiotherapy (WBRT) followed by stereotactic radiosurgery (SRS) reirradiation (Group 1), and 17 received SRS followed by WBRT reirradiation (Group 2)...
October 5, 2016: Journal of Radiation Research
https://www.readbyqxmd.com/read/27693225/salvage-external-beam-radiotherapy-for-locally-recurrent-prostate-cancer-after-definitive-brachytherapy
#13
Michael S Rutenberg, Moshe Meister, Pradip P Amin, Arif Hussain, Michael J Naslund, Young Kwok
PURPOSE: Patients with locally recurrent prostate cancer after definitive prostate brachytherapy have few evidence-based salvage options. We evaluate the efficacy and treatment-related side-effects of salvage external-beam radiotherapy (EBRT) after definitive prostate brachytherapy (PBT). METHODS AND MATERIALS: Eleven patients previously treated with definitive PBT and with biopsy-proven local-only recurrence received salvage reirradiation with EBRT. Genitourinary (GU) function was assessed with International Prostate Symptom Scores...
September 28, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27688100/patterns-of-failure-after-reirradiation-with-intensity-modulated-radiation-therapy-and-the-competing-risk-of-out-of-field-recurrences
#14
Danielle N Margalit, Bhupendra Rawal, Paul J Catalano, Robert I Haddad, Laura A Goguen, Donald J Annino, Sewanti A Limaye, Jochen H Lorch, Annie W Lavigne, Jonathan D Schoenfeld, David J Sher, Roy B Tishler
PURPOSE: To describe patterns of failure (POF) after reirradiation (reRT) with intensity modulated radiation therapy (IMRT) for recurrent/second primary squamous cell carcinoma of the head and neck. METHODS: From 08/2004-02/2013, 75 consecutive patients received reRT with IMRT. Gross tumor was generally treated with a 5mm planning target volume (PTV) margin. For postoperative cases, a 5mm PTV was added to the clinical target volume which included the postoperative bed...
October 2016: Oral Oncology
https://www.readbyqxmd.com/read/27675704/central-volume-target-overlap-and-esophageal-dose-predict-for-toxicity-in-a-prospective-study-of-reirradiation-for-non-small-cell-lung-carcinoma-using-proton-therapy
#15
H H Chao, A T Berman, R Mick, C Ciunci, P E Gabriel, H Lin, S Both, C Langer, K Lelionis, R Rengan, K Prabhu, W F Hartsell, C B Simone, J P Plastaras
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675641/efficacy-of-pulsed-low-dose-rate-reirradiation-results-from-a-phase-1-clinical-trial
#16
J E Meyer, T J Galloway, K Ruth, E A Ross, M K Buyyounouski, T L Klayton, M A Hallman, S E Weiss, S B Hayes, J Leahy, G Duncan, R A Price, E M Horwitz, C M C Ma
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675580/reirradiation-stereotactic-body-radiation-therapy-sbrt-for-spinal-metastases-a-multi-institutional-outcome-analysis
#17
A H Hashmi, M Guckenberger, R Kersh, P C Gerszten, F Mantel, I S Grills, J C Flickinger, J Shin, D Fahim, B Winey, K S Oh, J Cho, D Letourneau, J P Sheehan, A Sahgal
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675561/multi-institution-analysis-of-intensity-modulated-radiation-therapy-based-reirradiation-for-head-and-neck-cancer-prognostic-factors-and-recursive-partitioning-analysis-for-overall-survival
#18
M C Ward, N Riaz, J J Caudell, N E Dunlap, D Isrow, S J Zakem, J Dault, M J Awan, J Vargo, D E Heron, K A Higgins, J J Beitler, M Yao, M Machtay, F Siddiqui, A Trotti, N Lee, S Koyfman
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675560/multi-institution-analysis-of-intensity-modulated-radiation-therapy-based-reirradiation-for-head-and-neck-cancer-improved-risk-benefit-profile-in-the-modern-era
#19
J J Caudell, M C Ward, S Koyfman, N Riaz, N E Dunlap, D Isrow, S J Zakem, M J Awan, J Vargo, D E Heron, K A Higgins, J J Beitler, M Yao, M Machtay, A Trotti, F Siddiqui, N Lee
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27675558/optimal-treatment-selection-of-stereotactic-body-radiation-therapy-and-intensity-modulated-radiation-therapy-for-reirradiation-of-head-and-neck-cancer-a-multi-institution-comparison
#20
J Vargo, M C Ward, J J Caudell, N Riaz, N E Dunlap, D Isrow, S J Zakem, J Dault, M J Awan, K A Higgins, J J Beitler, M Yao, M Machtay, F Siddiqui, A Trotti, N Lee, S Koyfman, D E Heron
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
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