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https://www.readbyqxmd.com/read/27936443/antifungal-potential-of-marine-natural-products
#1
REVIEW
Ebaa M El-Hossary, Cheng Cheng, Mostafa M Hamed, Ashraf Nageeb El-Sayed Hamed, Knut Ohlsen, Ute Hentschel, Usama Ramadan Abdelmohsen
Fungal diseases represent an increasing threat to human health worldwide which in some cases might be associated with substantial morbidity and mortality. However, only few antifungal drugs are currently available for the treatment of life-threatening fungal infections. Furthermore, plant diseases caused by fungal pathogens represent a worldwide economic problem for the agriculture industry. The marine environment continues to provide structurally diverse and biologically active secondary metabolites, several of which have inspired the development of new classes of therapeutic agents...
November 14, 2016: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/27936432/the-role-of-the-water-tankers-market-in-water-stressed-semi-arid-urban-areas-implications-on-water-quality-and-economic-burden
#2
Kinda Constantine, May Massoud, Ibrahim Alameddine, Mutasem El-Fadel
Population growth and development are associated with increased water demand that often exceeds the capacity of existing resources, resulting in water shortages, particularly in urban areas, where more than 60% of the world's population resides. In many developing communities, shortages often force households to depend on water tankers amongst other potential sources for the delivery of water for domestic and/or potable use. While water tankers have become an integral part of the water supply system in many countries, the sector is often unregulated and operates with little governmental supervision...
December 6, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27936379/clinical-and-epidemiological-characteristics-associated-with-unfavorable-tuberculosis-treatment-outcomes-in-tb-hiv-co-infected-patients-in-brazil-a-hierarchical-polytomous-analysis
#3
Thiago Nascimento do Prado, Jayant V Rajan, Angélica Espinosa Miranda, Elias Dos Santos Dias, Lorrayne Beliqui Cosme, Lia Gonçalves Possuelo, Mauro N Sanchez, Jonathan E Golub, Lee W Riley, Ethel Leonor Maciel
BACKGROUND: TB patients co-infected with HIV have worse treatment outcomes than non-coinfected patients. How clinical characteristics of TB and socioeconomic characteristics influence these outcomes is poorly understood. Here, we use polytomous regression analysis to identify clinical and epidemiological characteristics associated with unfavorable treatment outcomes among TB-HIV co-infected patients in Brazil. METHODS: TB-HIV cases reported in the Brazilian information system (SINAN) between January 1, 2001 and December 31, 2011 were identified and categorized by TB treatment outcome (cure, default, death, and development of MDR TB)...
December 6, 2016: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27936361/the-relationship-between-drinking-pattern-social-capital-and-area-deprivation-findings-from-the-health-survey-for-england
#4
Linda Ng Fat, Shaun Scholes, Stephen Jivraj
OBJECTIVE: The purpose of this study was to establish the relationships between heavy episodic and drinking frequency with area-deprivation and social capital in England. METHOD: Using the Health Survey for England 2002-2006, a nationally representative crosssectional survey (N = 54,422), multilevel logistic regression models with individuals nested within primary sampling units were carried out, stratified by sex, on (a) drinkers versus nondrinkers, (b) heavy episodic drinking versus drinking less (on the heaviest drinking day), and (c) fewer than 2 drink-free days versus at least 2 drink-free days...
January 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/27936308/amidinyl-radical-formation-through-anodic-n-h-bond-cleavage-and-its-application-in-aromatic-c-h-bond-functionalization
#5
Huai-Bo Zhao, Zhong-Wei Hou, Zhan-Jiang Liu, Ze-Feng Zhou, Jinshuai Song, Hai-Chao Xu
We report herein an atom-economical and sustainable approach to access amidinyl radical intermediates through the anodic cleavage of N-H bonds. The resulting nitrogen-centered radicals undergo cyclizations with (hetero)arenes, followed by rearomatization, to afford functionalized tetracyclic benzimidazoles in a highly straightforward and efficient manner. This metal- and reagent-free C-H/N-H cross-coupling reaction exhibits a broad substrate scope and proceeds with high chemoselectivity.
December 9, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27936302/highly-site-selective-formal-5-2-and-4-2-annulations-of-isoxazoles-with-heterosubstituted-alkynes-by-platinum-catalysis-rapid-access-to-functionalized-1-3-oxazepines-and-2-5-dihydropyridines
#6
Wen-Bo Shen, Xin-Yu Xiao, Qing Sun, Bo Zhou, Xin-Qi Zhu, Juan-Zhu Yan, Xin Lu, Long-Wu Ye
Platinum-catalyzed formal [5+2] and [4+2] annulations of isoxazoles with heterosubstituted alkynes enabled the atom-economical synthesis of valuable 1,3-oxazepines and 2,5-dihydropyridines, respectively. Importantly, this Pt catalysis not only led to unique reactivity dramatically divergent from that observed under Au catalysis, but also proceeded via unprecedented α-imino platinum carbene intermediates.
December 9, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27936288/staple-crops-biofortified-with-increased-vitamins-and-minerals-considerations-for-a-public-health-strategy
#7
Maria Nieves Garcia-Casal, Juan Pablo Peña-Rosas, Boitshepo Giyose
Biofortification of staple crops has been proposed as a strategy to address micronutrient malnutrition, particularly with respect to insufficient intake of vitamin A, iron, zinc, and folate. The World Health Organization, in collaboration with the Food and Agriculture Organization of the United Nations and the Sackler Institute for Nutrition Science at the New York Academy of Sciences, convened a technical consultation entitled "Staple Crops Biofortified with Vitamins and Minerals: Considerations for a Public Health Strategy" in April 2016...
December 9, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27936263/-highlighting-the-lived-experience-of-families-family-peer-support-services-initiative
#8
Catherine Briand, Rose-Anne St-Paul, Francine Dubé
To support personal recovery, any person with a mental illness should have access to a range of practices recommended by scientific evidence. The peer support are some of the services recommended by the Mental Health Commission of Canada for the reduction of the economic and social burden of mental illness. If peer support from families is poorly documented, peer support and mutual aid from users have been the subject of several studies. Based on two studies in which she participated, addressing the needs of families, and its experience as a non-profit support organization for families, the Quebec Society of Schizophrenia (QSS) has reflected on the family support problem upon entry in the health system as well as the involvement of families as peer support...
2016: Santé Mentale Au Québec
https://www.readbyqxmd.com/read/27936257/-institutions-without-history-an-investigation-into-the-archives-of-a-private-psychiatric-hospital-france-1930-1950
#9
Hervé Guillemain
Objectives Discovered by following the story of a Parisian patient, l'Hôpital psychiatrique de Saint-Rémy opened in 1937 in the east of France. It is a special institution that was created for profit and in an emergency context during the 1930s.Methods Due to the absence of administrative records, the history of this institution can be written only by using the archives of the Parisian administration and patient records. The story of this special institution allows several issues in the historiography of psychiatry: the funding of mental health, the patient transfers, the revival of the criticism against the psychiatric hospital...
2016: Santé Mentale Au Québec
https://www.readbyqxmd.com/read/27936248/light-mediated-generation-of-silver-nanoparticles-by-spinach-thylakoids-chloroplasts
#10
Nisha Shabnam, P Sharmila, Hyunook Kim, P Pardha-Saradhi
The unique potential of chloroplasts/thylakoids to harness light energy to transport electrons from H2O to various entities was exploited for reduction of Ag+ to generate nanoparticles (NPs). Spinach thylakoids/chloroplasts turned AgNO3 solutions brown in light, but not in dark. Besides showing Ag-NPs specific surface plasmon resonance band, these brown solutions showed presence of 5-30 nm crystalline NPs composed of Ag. Powder X-ray diffraction (PXRD) analysis revealed that Ag-NPs were biphasic composed of face-centered cubic Ag0 and cubic Ag2O...
2016: PloS One
https://www.readbyqxmd.com/read/27936184/freshwater-detention-by-oyster-reefs-quantifying-a-keystone-ecosystem-service
#11
David A Kaplan, Maitane Olabarrieta, Peter Frederick, Arnoldo Valle-Levinson
Oyster reefs provide myriad ecosystem services, including water quality improvement, fisheries and other faunal support, shoreline protection from erosion and storm surge, and economic productivity. However, their role in directing flow during non-storm conditions has been largely neglected. In regions where oyster reefs form near the mouth of estuarine rivers, they likely alter ocean-estuary exchange by acting as fresh water "dams". We hypothesize that these reefs have the potential to detain fresh water and influence salinity over extensive areas, thus providing a "keystone" ecosystem service by supporting estuarine functions that rely on the maintenance of estuarine (i...
2016: PloS One
https://www.readbyqxmd.com/read/27936096/factors-associated-with-disability-in-rural-bangladesh-bangladesh-population-based-diabetes-and-eye-study-bpdes
#12
Fakir M Amirul Islam, Jahar L Bhowmik, Silvia Z Islam, Andre M N Renzaho, Janet E Hiller
BACKGROUND: To assess factors associated with disability in a rural district of Bangladesh. METHODS: Using a population-based systematic sampling technique, data were collected from 3104 adults aged ≥ 30 years from the Banshgram union of Narail district. Data collected included an interviewer administered questionnaire to report physical disabilities including impairment that prevents engagement with paid work, visual, hearing, and mobility as well as mental disabilities...
2016: PloS One
https://www.readbyqxmd.com/read/27936078/associations-between-childhood-parental-mental-health-difficulties-and-depressive-symptoms-in-late-adulthood-the-influence-of-life-course-socioeconomic-health-and-lifestyle-factors
#13
Viola Angelini, Bart Klijs, Nynke Smidt, Jochen O Mierau
BACKGROUND: Depression among older adults (i.e., the 50+) is a major health concern. The objective of this study is to investigate whether growing up with a parent suffering from mental health problems is associated with depressive symptoms in late-adulthood and how this association is influenced by life-course socio-economic, health and lifestyle factors in childhood and late adulthood. METHODS: We used life-history data from the SHARE survey, consisting of 21,127 participants living in 13 European countries...
2016: PloS One
https://www.readbyqxmd.com/read/27936019/ultrasensitive-detection-of-porcine-epidemic-diarrhea-virus-from-fecal-samples-using-functionalized-nanoparticles
#14
Na Xing, Xiaoxiao Guan, Bin An, Beibei Cui, Zengguo Wang, Xiaoya Wang, Xiujuan Zhang, Qian Du, Xiaomin Zhao, Yong Huang, Dewen Tong
Porcine epidemic diarrhea virus (PEDV) is the main causative agent of porcine diarrhea, which has resulted in devastating damage to swine industry and become a perplexed global problem. PEDV infection causes lesions and clinical symptoms, and infected pigs often succumb to severe dehydration. If there is not a timely and effective method to control its infection, PEDV will spread rapidly across the whole swine farm. Therefore, preclinical identification of PEDV is of great significance for preventing the outbreak and spread of this disease...
2016: PloS One
https://www.readbyqxmd.com/read/27935946/the-economics-of-a-successful-raccoon-rabies-elimination-program-on-long-island-new-york
#15
Julie L Elser, Laura L Bigler, Aaron M Anderson, Joanne L Maki, Donald H Lein, Stephanie A Shwiff
Raccoon rabies is endemic in the eastern U.S.; however, an epizootic had not been confirmed on Long Island, New York until 2004. An oral rabies vaccination (ORV) program was initiated soon after the first rabies-positive raccoon was discovered, and continued until raccoon rabies was eliminated from the vaccination zone. The cost-effectiveness and economic impact of this rabies control program were unknown. A public health surveillance data set was evaluated following the ORV program on Long Island, and is used here as a case study in the health economics of rabies prevention and control efforts...
December 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27935905/socio-demographic-epidemiological-and-environmental-determinants-of-acute-gastroenteritis-in-western-india
#16
M P Rupani, A V Tridevi, M P Singh, M N Tundia, K N Patel, K D Parikh, V B Parmar
INTRODUCTION: An outbreak of acute gastroenteritis had occurred in Rajpara village of Bhavnagar district. The objective of this study was to find out the socio-demographic, epidemiological and environmental determinants of this outbreak. METHODS: A case-control study was conducted in Rajpara village among 238 cases of acute gastroenteritis and an equal number of controls in January 2015. Multiple logistic regression was used for identifying the variables independently predicting acute gastroenteritis...
January 2016: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/27935798/health-gains-and-financial-protection-provided-by-the-ethiopian-mental-health-strategy-an-extended-cost-effectiveness-analysis
#17
Kjell Arne Johansson, Kirsten Bjerkreim Strand, Abebaw Fekadu, Dan Chisholm
BACKGROUND: Mental and neurological (MN) health care has long been neglected in low-income settings. This paper estimates health and non-health impacts of fully publicly financed care for selected key interventions in the National Mental Health Strategy in Ethiopia for depression, bipolar disorder, schizophrenia and epilepsy. METHODS: A methodology of extended cost-effectiveness analysis (ECEA) is applied to MN health care in Ethiopia. The impact of providing a package of selected MN interventions free of charge in Ethiopia is estimated for: epilepsy (75% coverage, phenobarbital), depression (30% coverage, fluoxetine, cognitive therapy and proactive case management), bipolar affective disorder (50% coverage, valproate and psychosocial therapy) and schizophrenia (75% coverage, haloperidol plus psychosocial treatment)...
October 9, 2016: Health Policy and Planning
https://www.readbyqxmd.com/read/27935788/evidence-of-query-theory-as-a-tool-to-assist-restrained-eaters
#18
Sudy Majd, Mark A Conley, Elke U Weber, Gerhard R Andlinger
OBJECTIVES: Using theories from decision-making and behavioral economics, we conducted a study to improve understanding of the decisions of Restrained Eaters. We identified Restrained Eaters via the Revised Restraint Questionnaire. METHODS: One hundred two (N = 102) participants were each randomly assigned to an endowment condition and asked to list their thoughts about 2 products. RESULTS: We found a significant interaction of endowment and thoughts on decisions...
January 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/27935777/acupuncture-and-chronic-pain-management
#19
Ladan Eshkevari
According to National Institute of Health Pathways to Prevention Workshop (2014), chronic pain affects an estimated 100 million Americans, with approximately 25 million people experiencing moderate to severe chronic pain, which negatively impacts their ability to function leading to a diminished quality of life. Pain is the primary reason Americans are on disability, which adds to the economic and social burden of suffering for the nation. Chronic pain costs are estimated to be between 560 and 630 billion per year...
January 2017: Annual Review of Nursing Research
https://www.readbyqxmd.com/read/27935746/effect-of-restaurant-types-on-compensation-claims-for-work-related-musculoskeletal-disorders-in-france
#20
Pierre Nanyan, Mondher Ben Charrada
AIMS: The economic burden of work-related musculoskeletal disorders (WMSDs) is industry-specific.The objective was to analyse compensation claims for WMSDs among restaurant workers in France taking into account the type of restaurant. METHODS: Data for 2014 were obtained from the French National Health Insurance Fund for Salaried Workers. A chi-square test was used to compare claims, incapacity and lost work days rates in different type of restaurant. RESULTS: Prevalence for WMSDs, differed significantly by the type of kitchens: collective restaurant (7...
December 9, 2016: International Journal of Occupational Safety and Ergonomics: JOSE
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