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https://www.readbyqxmd.com/read/29768651/cannabinoid-hyperemesis-syndrome-reports-of-fatal-cases
#1
Mahra Nourbakhsh, Angela Miller, Jeff Gofton, Graham Jones, Bamidele Adeagbo
Cannabinoid hyperemesis syndrome (CHS) is one of the more clinically challenging effects of cannabis consumption. It is characterized by cyclic attacks of nausea and vomiting in chronic cannabinoid users and learned behavior of compulsive hot bathing. The deaths of a 27-year-old female, a 27-year-old male, and a 31-year-old male with a history of CHS are reported. The decedents had a history of cyclical nausea and vomiting, chronic cannabinoid use and negative laboratory, radiological and endoscopic findings...
May 16, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29745720/cannabinoid-hyperemesis-syndrome
#2
Eduardo Valdivielso Cortázar, Patricia Ucha Abal, Pedro Alonso Aguirre
We report the case of a 30-year-old female with a history of cannabis use from 16 years of age. The patient presented to the Gastroenterology Clinic due to cyclical epigastric pain associated with postprandial stomach heaviness, nausea and vomiting. She was admitted due to a worsening of her condition, which prevented her from leading a normal life.
May 2018: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/29697487/family-health-related-quality-of-life-in-pediatric-cyclic-vomiting-syndrome
#3
Jennifer Wang-Hall, B U K Li, Sally E Tarbell
OBJECTIVE: The aim of the study was to evaluate the relationship of disease characteristics and child anxiety symptoms to family health-related quality of life (FHRQoL) in youth with cyclic vomiting syndrome (CVS). METHODS: Forty-two parents of youth ages 8 to 18 years diagnosed with CVS completed the Family Impact Module of the PedsQL, a measure of the impact of the child's illness on the family. We evaluated the relationship of disease characteristics and child and parent proxy reports of anxiety symptoms on the Screen for Childhood Anxiety and Related Emotional Disorders to FHRQoL...
May 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29610182/unusual-presentations-of-dystrophinopathies-in-childhood
#4
Nicholas M Allen, Alice Ewer, Vasiliki Nakou, Ele Konstantoulaki, Elizabeth Wraige, Vasantha Gowda, Heinz Jungbluth
X-linked recessive mutations in the dystrophin gene are one of the most common causes of inherited neuromuscular disorders in humans. Duchenne muscular dystrophy, the most common phenotype, and Becker muscular dystrophy are often recognizable by certain clinical features; however, less frequent presentations require a higher degree of suspicion. In this article, we describe a series of 6 children (4 boys, 2 girls) referred to a tertiary pediatric neuromuscular clinic for isolated elevated creatine kinase levels (range: 720-7000 IU/L) identified on initial assessment for otherwise unexplained transaminase elevations ( n = 2), a social communication disorder ( n = 3), and exertional myalgia and/or rhabdomyolysis ( n = 1)...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29601304/episodic-syndromes-of-childhood-associated-with-migraine
#5
Amy A Gelfand
PURPOSE OF REVIEW: This review covers recent advances in our understanding of episodic syndromes that may be associated with migraine in children and adolescents, as well as what is known about the treatment of these disorders. RECENT FINDINGS: The episodic syndromes include benign paroxysmal torticollis, benign paroxysmal vertigo, abdominal migraine, and cyclic vomiting syndrome. Infant colic, or excessive crying in an otherwise healthy and well fed infant, may also fit into this category and is included in the appendix section of the most recent edition of the International Classification of Headache Disorders...
March 29, 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29560069/cannabinoid-hyperemesis-syndrome-public-health-implications-and-a-novel-model-treatment-guideline
#6
Jeff Lapoint, Seth Meyer, Charles K Yu, Kristi L Koenig, Roneet Lev, Sayone Thihalolipavan, Katherine Staats, Christopher A Kahn
Introduction: Cannabinoid hyperemesis syndrome (CHS) is an entity associated with cannabinoid overuse. CHS typically presents with cyclical vomiting, diffuse abdominal pain, and relief with hot showers. Patients often present to the emergency department (ED) repeatedly and undergo extensive evaluations including laboratory examination, advanced imaging, and in some cases unnecessary procedures. They are exposed to an array of pharmacologic interventions including opioids that not only lack evidence, but may also be harmful...
March 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29556858/cyclic-vomiting-syndrome-in-children
#7
REVIEW
Anne Donnet, Sylvain Redon
PURPOSE OF REVIEW: Cyclic vomiting syndrome (CVS) is a misrecognized and probably underdiagnosed episodic syndrome associated with migraine, occurring preferentially in childhood. Attacks are stereotyped for each individual, with predictable periodicity. This review summarizes recent clinical and paraclinical observations in this syndrome, and current approaches in explorations and therapeutics. RECENT FINDINGS: Clinical phenotype during prodromal, vomiting, and recovery phases contains visceral and neuropsychological symptoms, but also cranial and systemic symptoms...
March 19, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29545633/chronic-nausea-and-vomiting-evaluation-and-treatment
#8
REVIEW
Brian E Lacy, Henry P Parkman, Michael Camilleri
Nausea is an uneasy feeling in the stomach while vomiting refers to the forceful expulsion of gastric contents. Chronic nausea and vomiting represent a diverse array of disorders defined by 4 weeks or more of symptoms. Chronic nausea and vomiting result from a variety of pathophysiological processes, involving gastrointestinal and non-gastrointestinal causes. The prevalence of chronic nausea and vomiting is unclear, although the epidemiology of specific conditions, such as gastroparesis and cyclic vomiting syndrome, is better understood...
March 15, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29528207/functional-gastrointestinal-disorders-functional-gastrointestinal-disorders-in-children
#9
Abdul Waheed, Michael Malone, Samiullah Samiullah
Functional gastrointestinal disorders (FGIDs) are common among children and cause tremendous distress for patients and families. Family physicians should know how to diagnose and manage some of the more common childhood FGIDs. These include infant regurgitation, infant colic, infant dyschezia, cyclic vomiting syndrome, functional nausea and vomiting, functional diarrhea and constipation, abdominal migraine, and nonspecific functional abdominal pain. Diagnosis requires a thorough history and physical examination to rule out red flag signs and symptoms for structural or organic etiologies...
March 2018: FP Essentials
https://www.readbyqxmd.com/read/29528205/functional-gastrointestinal-disorders-functional-upper-gastrointestinal-disorders-in-adults
#10
Michael Malone, Abdul Waheed, Samiullah Samiullah
Functional upper gastrointestinal disorders are common and cause significant patient distress and health care cost. These disorders typically are classified as either esophageal or gastroduodenal. Functional esophageal disorders include functional heartburn, reflux hypersensitivity, and functional dysphagia. Functional gastroduodenal disorders include functional dyspepsia and cyclic vomiting syndrome. Cyclic vomiting syndrome should be suspected in any patient with multiple episodes of vomiting with no apparent cause that completely resolve between episodes...
March 2018: FP Essentials
https://www.readbyqxmd.com/read/29520160/cyclic-vomiting-syndrome-diagnostic-approach-and-current-management-strategies
#11
REVIEW
William J Hayes, Deidra VanGilder, Joseph Berendse, Michael D Lemon, John A Kappes
Cyclic vomiting syndrome (CVS) is a disorder characterized by episodes of nausea and vomiting lasting for 1-5 days followed by asymptomatic periods. The etiology of CVS is unknown, but it shares similar characteristics to migraine headaches. CVS is generally classified as having four phases: prodromal, acute/vomiting/hyperemesis, recovery, and remission/interepisodic. Current management strategies include trigger avoidance, abortive and prophylactic medication therapies, and supportive care. The goal of therapy for the remission phase is prophylaxis of further episodes...
2018: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/29484898/an-overview-of-the-clinical-management-of-cyclic-vomiting-syndrome-in-childhood
#12
Claudio Romano, Valeria Dipasquale, Anna Rybak, Donatella Comito, Osvaldo Borrelli
This narrative review provides an update on cyclic vomiting syndrome pathogenesis, diagnosis and management, based upon studies published after the 2008 North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) official recommendations. The review began with a comprehensive PubMed/Medline search for "cyclic vomiting syndrome", "periodic syndromes" and "pediatrics" from 2000 up to October 2017. Additional papers were identified by reviewing the re-ference lists of retrieved publications...
March 23, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29484154/cyclic-vomiting-syndrome-a-case-series-and-review-of-the-literature
#13
REVIEW
Jessica Shearer, Pavit Luthra, Alexander C Ford
Objective: Cyclic vomiting syndrome (CVS) is under-recognised. Treatment is difficult as the pathophysiology is incompletely understood. We report our experience of treating patients with amitriptyline, and review the literature to summarise symptoms and associated features, epidemiology, potential pathophysiological mechanisms, differential diagnoses and treatment. Design: Consecutive adult patients with CVS were identified during a 5-year period from January 2010 until December 2015...
January 2018: Frontline Gastroenterology
https://www.readbyqxmd.com/read/29470758/cyclic-vomiting-syndrome-the-nervous-system-has-the-guts
#14
EDITORIAL
Ryuji Sakakibara
No abstract text is available yet for this article.
April 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29446794/migraine-variants-in-children
#15
A David Rothner
Migraine in children can manifest in ways that are markedly different from adult migraines. In children, migraine variants are often unaccompanied by headache and include conditions such as cyclic vomiting and abdominal migraine. Children who experience these conditions are often thought to have a disorder of the gastrointestinal tract, and when evaluation is unremarkable they may be diagnosed as having a conversion reaction. Complicated migraines, on the other hand, are often accompanied by focal neurological symptoms such as ataxia, hemiparesis, or altered level of consciousness that evoke great consternation in the examining clinician...
February 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29442203/cyclic-vomiting-syndrome-epidemiology-diagnosis-and-treatment
#16
REVIEW
Sanjay Bhandari, Pinky Jha, Abhishek Thakur, Abhipsa Kar, Harrison Gerdes, Thangam Venkatesan
Cyclic-vomiting syndrome (CVS) is a chronic functional gastrointestinal disorder characterized by recurrent episodes of nausea and vomiting. Although once thought to be a pediatric disorder, there has been a considerable increase in recognition of CVS in adults. The exact pathogenesis is unknown and several theories have been proposed. Migraine and CVS share a similar pathophysiology as suggested by several studies. Since there are no specific biomarkers available for this disorder, physicians should rely on Rome criteria for the diagnosis...
April 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29437134/cyclic-vomiting-syndrome
#17
EDITORIAL
Michael S Foreman, Tammy Camp
No abstract text is available yet for this article.
February 2018: Pediatrics in Review
https://www.readbyqxmd.com/read/29373437/yield-and-costs-of-evaluating-children-with-cyclic-vomiting-syndrome
#18
Chantal Lucia-Casadonte, Kaitlin Whaley, Ashish Chogle
BACKGROUND: Cyclic vomiting syndrome (CVS) clinical guidelines recommend an algorithm of basic testing for standard patients, and more targeted testing, including laboratory and imaging studies, in the presence of specific red flags. The cost effectiveness of this screening of children with suspected CVS is lacking. OBJECTIVES: To determine if screening studies in CVS patients results in diagnostic change, and to estimate their healthcare cost. METHOD: Charts of patients (1-18 years) with suspected CVS were retrospectively reviewed at a single center...
January 25, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29311736/continuing-medical-education-questions-january-2018-prophylactic-therapy-of-cyclic-vomiting-syndrome-in-children-comparison-of-amitriptyline-and-cyproheptadine-a-randomized-clinical-trial
#19
https://www.readbyqxmd.com/read/29310960/cannabinoid-hyperemesis-syndrome-pathophysiology-and-treatment-in-the-emergency-department
#20
John R Richards
BACKGROUND: Cannabinoid hyperemesis syndrome (CHS) is a challenging clinical disorder. CHS patients frequently present to the emergency department and may require treatment for intractable emesis, dehydration, and electrolyte abnormalities. Thought to be a variant of cyclic vomiting syndrome, CHS has become more prevalent with increasing cannabis potency and use, as enabled by various states having legalized the recreational use of cannabis. OBJECTIVE: This aim of this review is to investigate the pathophysiology of CHS and evaluate the published literature on pharmacologic treatment in the emergency department...
March 2018: Journal of Emergency Medicine
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