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Pitting edema

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https://www.readbyqxmd.com/read/27906058/vascular-endothelial-growth-factor-levels-and-rheumatic-diseases-of-the-elderly
#1
Perrine Smets, Valérie Devauchelle-Pensec, Paul-Olivier Rouzaire, Bruno Pereira, Marc Andre, Martin Soubrier
BACKGROUND: Increasing vascular endothelial growth factor (VEGF) has been reported in remitting symmetrical seronegative synovitis with pitting edema (RS3PE) syndrome, rheumatoid arthritis (RA), polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). The aim of this study was to compare VEGF levels in patients over 60 years of age who have RS3PE, RA, PMR or GCA so as to determine whether elevated VEGF is specific for a rheumatic disease, the inflammation or edema that occurs with these pathological conditions...
December 1, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27826968/a-case-of-type-2-hereditary-angioedema-with-serping1-mutation
#2
Da Woon Sim, Kyung Hee Park, Jae Hyun Lee, Jung Won Park
Hereditary angioedema is a disease of congenital deficiency or functional defect in the C1 esterase inhibitor (C1-INH) consequent to mutation in the SERPING1 gene, which encodes C1-INH. This disease manifests as recurrent, non-pitting, non-pruritic subcutaneous, or submucosal edema as well as an erythematous rash in some cases. These symptoms result from the uncontrolled localized production of bradykinin. The most commonly affected sites are the extremities, face, gastrointestinal tract, and respiratory system...
January 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/27822948/delayed-high-output-heart-failure-due-to-arteriovenous-fistula-complicated-with-herniated-disc-surgery
#3
Taeshik Park, Sang Ho Park, Alok Arora
A 36-year-old male presented with progressive exertional dyspnea over months. Physical examination showed jugular venous distension, lung crecipitations, femoral bruit and pitting pedal edema. Echocardiogram showed a dilated right ventricle with severe pulmonary hypertension and a non collapsing inferior vena cava (IVC). On right heart catheterization, IVC oxygen saturation was noted at 92% suggesting arterial mixing; a computed tomography of the abdomen showed a fistula between the right common iliac artery to the right common iliac vein at L4 level and a massive IVC; this was linked to trauma from a disectomy done 16 years ago at L4-L5 level...
December 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27814935/diuretic-resistance
#4
Ewout J Hoorn, David H Ellison
Diuretic resistance is defined as a failure to achieve the therapeutically desired reduction in edema despite a full dose of diuretic. The causes of diuretic resistance include poor adherence to drug therapy or dietary sodium restriction, pharmacokinetic issues, and compensatory increases in sodium reabsorption in nephron sites that are not blocked by the diuretic. To illustrate the pathophysiology and management of diuretic resistance, we describe a patient with nephrotic syndrome. This patient presented with generalized pitting edema and weight gain despite the use of oral loop diuretics...
November 1, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27778389/beckwith-wiedemann-syndrome-and-primary-lymphedema-of-the-lower-extremity
#5
Usha E A Beijnen, Reid A Maclellan, Jeremy A Goss, Javier A Couto, Dennis J Konczyk, Arin K Greene
Beckwith-Wiedemann syndrome is the most common genetic overgrowth syndrome. Patients with Beckwith-Wiedemann syndrome may have hemihypertrophy, but their lymphatic vasculature is intact. We present a child with Beckwith-Wiedemann syndrome and lower extremity enlargement thought to be due to hemihypertrophy that was instead diagnosed with primary lymphedema. There are many causes of leg overgrowth in the pediatric population and misdiagnosis is common. While extremity enlargement secondary to hemihypertrophy may occur in 15% of patients with Beckwith-Wiedemann syndrome, progression and pitting edema only occur in primary lymphedema...
October 25, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27770788/bioelectrical-impedance-analysis-bia-of-the-association-of-the-japanese-kampo-concept-suidoku-fluid-disturbance-and-the-body-composition-of-women
#6
Aya Murakami, Daisuke Kobayashi, Toshio Kubota, Niina Zukeyama, Haru Mukae, Norihiro Furusyo, Mosaburo Kainuma, Takao Shimazoe
BACKGROUND: In Japanese Kampo medical practice, suidoku (fluid disturbance) is one of the most important concepts for selecting the proper medication. Suidoku is an excessive or uneven distribution of fluid that is indicated by splashing sounds and pitting edema. However, few objective reports about suidoku have been published. Bioelectrical impedance analysis (BIA) uses resistance values obtained from weak electrical currents to estimate body composition, including intracellular and extracellular water and muscle and fat mass...
October 22, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27754342/novel-catalytically-inactive-pii-metalloproteinases-from-a-viperid-snake-venom-with-substitutions-in-the-canonical-zinc-binding-motif
#7
Erika Camacho, Libia Sanz, Teresa Escalante, Alicia Pérez, Fabián Villalta, Bruno Lomonte, Ana Gisele C Neves-Ferreira, Andrés Feoli, Juan J Calvete, José María Gutiérrez, Alexandra Rucavado
Snake venom metalloproteinases (SVMPs) play key biological roles in prey immobilization and digestion. The majority of these activities depend on the hydrolysis of relevant protein substrates in the tissues. Hereby, we describe several isoforms and a cDNA clone sequence, corresponding to PII SVMP homologues from the venom of the Central American pit viper Bothriechis lateralis, which have modifications in the residues of the canonical sequence of the zinc-binding motif HEXXHXXGXXH. As a consequence, the proteolytic activity of the isolated proteins was undetectable when tested on azocasein and gelatin...
October 12, 2016: Toxins
https://www.readbyqxmd.com/read/27668205/aortic-dissection-accompanied-by-preeclampsia-in-a-postpartum-young-woman
#8
Jin-Wan Park, Su-Mi Kim, Gyu-Bong Yu, Yun-Dan Kang
Aortic dissection is very rare in obstetrics, but it is a fatal disease. A 37-weeks primigravida woman with dyspnea and pitting edema presented to our emergency room. The patient was diagnosed with preeclampsia and underwent an emergency cesarean section under spinal anesthesia. The patient complained of severe dyspnea after the cesarean section, and the chest computed tomography scan was done. With the finding of aortic dissection, cardiopulmonary arrest occurred 5 hours after the cesarean section, and the patient died without reaction to cardio-pulmonary resuscitation...
September 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27621935/hypoalbuminemia-and-malnutrition-associated-with-cow-s-milk-allergy-a-case-report
#9
Esma Altinel Acoglu, Meltem Akcaboy, Melahat Melek Oguz, Mustafa Kilic, Pelin Zorlu, Saliha Senel
INTRODUCTION: Cow's milk allergy is the most common food allergy in children. Symptoms usually involve the skin and the gastrointestinal and respiratory tracts. Gastrointestinal tract manifestations of cow's milk allergy are nonspecific, and are the only type that can be diagnosed in all age groups. Here, we report a rare case of cow's milk allergy in an infant with hypoalbuminemia and malnutrition. CASE PRESENTATION: A nine-month-old girl was admitted to Dr. Sami Ulus maternity and children's health and diseases training and research hospital, Ankara, Turkey, in September 2013, for weakness and swelling of the legs that had endured for two days...
June 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27609731/endocarditis-due-to-gemella-haemolysans-in-a-newly-diagnosed-multiple-myeloma-patient
#10
Dongyan Liu, Thomas Bateman, Elisabeth Carr, Paul Foster
An 87-year-old Caucasian woman with hypertension, diabetes mellitus type 2, and COPD was admitted with 1-week duration of back pain and weight gain. The physical examination revealed jugular venous distention, rales in the left lower lung field, and severe pitting edema over lower extremities. As workup for leukocytosis, blood cultures grew Gemella haemolysans. Subsequently, a transthoracic echocardiogram revealed vegetation on the non-coronary aortic leaflet and mild aortic stenosis. She was treated with ampicillin and gentamicin...
2016: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/27586538/leg-edema-with-s-amlodipine-vs-conventional-amlodipine-given-in-triple-therapy-for-hypertension-a-randomized-double-blind-controlled-clinical-trial
#11
Priyadarshani Galappatthy, Yasindu C Waniganayake, Mohomad I M Sabeer, Thusitha J Wijethunga, Gamini K S Galappatthy, Ruvan Ai Ekanayaka
BACKGROUND: Leg edema is a common adverse effect of dihydropyridine Calcium Channel Blockers (CCB) that may need dose reduction or drug withdrawal, adversely affecting the antihypertensive efficacy. Leg edema is reported to occur less often with (S)-amlodipine compared to conventional racemic amlodipine. We aimed to find the incidence of leg edema as a primary outcome and antihypertensive efficacy with (S)-amlodipine compared to conventional amlodipine. METHODS: This prospective, double-blind, controlled clinical trial randomized 172 hypertensive patients, not controlled on beta-blockers (BB) and angiotensin converting enzyme inhibitors/angiotensin receptor blockers (ACEI/ARB), to either conventional amlodipine (5-10 mg; n = 86) or (S)-amlodipine (2...
2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27529816/weight-estimation-tool-for-children-aged-6-to-59-months-in-limited-resource-settings
#12
Mark E Ralston, Mark A Myatt
IMPORTANCE: A simple, reliable anthropometric tool for rapid estimation of weight in children would be useful in limited-resource settings where current weight estimation tools are not uniformly reliable, nearly all global under-five mortality occurs, severe acute malnutrition is a significant contributor in approximately one-third of under-five mortality, and a weight scale may not be immediately available in emergencies to first-response providers. OBJECTIVE: To determine the accuracy and precision of mid-upper arm circumference (MUAC) and height as weight estimation tools in children under five years of age in low-to-middle income countries...
2016: PloS One
https://www.readbyqxmd.com/read/27509699/renal-disease-in-patients-infected-with-hepatitis-b-virus
#13
REVIEW
Ajay Jaryal, Vivek Kumar, Vishal Sharma
Infection with hepatitis B virus (HBV) can result in hepatic diseases which may include an asymptomatic non-replicative carrier state, immunotolerant phase characterized by high DNA levels without significant hepatic injury, immune-reactive phase characterized by occurrence of chronic hepatitis and fibrosis in the liver, or complications like cirrhosis or hepatocellular carcinoma. Extrahepatic manifestations may also accompany HBV infection. These may include serum sickness syndrome, polyarthralgia, polyarthritis, dermatologic manifestations like pitted keratolysis, urticaria, purpura, oral lichen planus or Gianotti-Crosti syndrome-a childhood papular eruption...
October 2015: Tropical Gastroenterology: Official Journal of the Digestive Diseases Foundation
https://www.readbyqxmd.com/read/27504558/spindle-cell-sarcoma-presenting-as-pancoast-syndrome
#14
Aliena Badshah, Salman Khan, Usman Saeed
This report describes a patient who presented with pancoast syndrome, secondary to spindle cell sarcoma of the lung. A 56-year man presented with dyspnea, engorged neck veins and bilateral upper limb pitting edema. The patient also had ptosis and miosis in the right eye. Right ulnar nerve palsy with atrophy of hand muscles was seen. His chest X-ray showed bilateral pleural effusion with an opacity involving the apex of the right lung along with mediastinal widening. Echocardiography revealed a pericardial effusion which was drained...
July 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27439425/idiopathic-remitting-seronegative-symmetrical-synovitis-with-pitting-edema-syndrome-associated-with-bilateral-pleural-and-pericardial-effusions-a-case-report
#15
Shozaburo Yanamoto, Jiro Fukae, Yurie Fukiyama, Shinsuke Fujioka, Shinji Ouma, Yoshio Tsuboi
BACKGROUND: Remitting seronegative symmetrical synovitis with pitting edema syndrome is characterized by symmetrical synovitis with pitting edema in the dorsum of the hands or feet. Most cases of remitting seronegative symmetrical synovitis with pitting edema syndrome are idiopathic, but some are secondary to malignancy, autoimmune disease, or neurodegenerative disorders. Pleural and pericardial effusions are unusual complications in idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome...
2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27320419/clinical-outcomes-in-the-first-year-of-remitting-seronegative-symmetrical-synovitis-with-pitting-edema-rs3pe-syndrome
#16
Tomoki Origuchi, Kazuhiko Arima, Masataka Umeda, Shin-Ya Kawashiri, Mami Tamai, Hideki Nakamura, Toshiaki Tsukada, Taiichiro Miyashita, Nozomi Iwanaga, Yasumori Izumi, Masako Furuyama, Fumiko Tanaka, Yojiro Kawabe, Toshiyuki Aramaki, Yukitaka Ueki, Katsumi Eguchi, Takaaki Fukuda, Atsushi Kawakami
OBJECTIVE: We investigated clinical outcomes in patients with remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome. METHODS: This is a retrospective multicenter study conducted in Nagasaki, Japan. We consecutively diagnosed a total of 41 patients with RS3PE syndrome between October 2003 and September 2012 and evaluated their outcomes from medical records from the first year of follow-up. RESULTS: Although an excellent initial response to corticosteroids was noted in all 41 patients, 34 (82...
June 20, 2016: Modern Rheumatology
https://www.readbyqxmd.com/read/27294836/the-ratio-of-epicardial-to-body-fat-improves-the-prediction-of-coronary-artery-disease-beyond-calcium-and-framingham-risk-scores
#17
Bai-Chin Lee, Wen-Jeng Lee, Shyh-Chyi Lo, Hsiu-Ching Hsu, Kuo-Liong Chien, Yeun-Chung Chang, Ming-Fong Chen
The association between epicardial fat and coronary artery disease (CAD) might be affected by general adiposity. We aimed to determine whether the percentage of epicardial adipose tissue (%EAT), defined as the mass ratio of epicardial fat to body fat, could improve prediction of asymptomatic CAD. We consecutively enrolled 846 adults who underwent coronary computed tomography angiography as part of a health check-up and assessed their coronary stenosis severity and epicardial fat mass. Body fat mass was measured by bioelectrical impedance analysis...
June 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27269656/-puffy-hand-syndrome
#18
Mickaël Chouk, Claire Vidon, Elise Deveza, Frank Verhoeven, Fabien Pelletier, Clément Prati, Daniel Wendling
Intravenous drug addiction is responsible for many complications, especially cutaneous and infectious. There is a syndrome, rarely observed in rheumatology, resulting in "puffy hands": the puffy hand syndrome. We report two cases of this condition from our rheumatologic consultation. Our two patients had intravenous drug addiction. They presented with an edema of the hands, bilateral, painless, no pitting, occurring in one of our patient during heroin intoxication, and in the other 2 years after stopping injections...
June 3, 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/27241546/adult-variant-of-self-healing-cutaneous-mucinosis-in-a-patient-with-epilepsy
#19
Reza Yaghoobi, Arezou Bagherzade, Maryam Aliabdi, Parvin Kheradmand, Afshin Kazerouni, Amir Feily
A 52-year-old woman was admitted with a 3 weeks history of periorbital edema and lips swelling. She developed several subcutaneous firm erythematous papules and nodules on the face, scalp and two indurated plaques on the upper back and left forearm. These lesions grew rapidly. The patient had a positive history of epileptic seizures since childhood. General examination was normal. There was a mild pitting edema on her hands and feet. Laboratory data were within normal limits. Histopathological examination revealed a well circumscribed accumulation of mucin in the dermis...
January 2016: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/27222015/clinical-characteristics-of-overhydration-in-patients-with-idiopathic-edema
#20
Young Rok Ham, Hae Ri Kim, Hong Jae Jeon, Yoo Hyung Kim, Jae Woong Jeon, Sarah Chung, Dae Eun Choi, Ki Ryang Na, Kang Wook Lee
BACKGROUND: Idiopathic edema (IE) is a common clinical syndrome. Designing treatment plans for IE is problematic because of the difficulty in assessing volume status. We aimed to evaluate volume status, measured by bioimpedance spectroscopy (BIS), and investigated clinical parameters associated with volume overload (VO) in patients with IE. METHODS: Patients with IE were defined as those with symptomatic edema and without abnormal renal function or any other apparent cause of edema...
2016: Nephron
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