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Extended-spectrum beta-lactamase

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https://www.readbyqxmd.com/read/28346533/correction-a-cross-sectional-study-of-colonization-rates-with-methicillin-resistant-staphylococcus-aureus-mrsa-and-extended-spectrum-beta-lactamase-esbl-and-carbapenemase-producing-enterobacteriaceae-in-four-swiss-refugee-centres
#1
Rein Jan Piso, Roman Käch, Roxana Pop, Daniela Zillig, Urs Schibli, Stefano Bassetti, Dominik M Meinel, Adrian Egli
[This corrects the article DOI: 10.1371/journal.pone.0170251.].
2017: PloS One
https://www.readbyqxmd.com/read/28345529/diversity-of-extended-spectrum-beta-lactamase-producing-escherichia-coli-rods
#2
Patrycja Zalas-Więcek, Tomasz Bogiel, Krzysztof Wiśniewski, Eugenia Gospodarek-Komkowska
INTRODUCTION: The aim of the study was to evaluate genetic relatedness and antimicrobial susceptibility of extended-spectrum beta-lactamase-producing E. coli strains isolated from patients hospitalized in the University Hospital in Bydgoszcz (Poland). MATERIAL AND METHODS: The study included 33 extended-spectrum beta-lactamase-producing E. coli strains isolated from 31 patients. The chromosomal DNA was extracted from the strains and separated by pulsed-field gel electrophoresis...
March 27, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28345184/spatial-molecular-epidemiology-of-carbapenem-resistant-and-new-delhi-metallo-beta-lactamase-blandm-producing-escherichia-coli-strains-from-farmed-piglets-of-india
#3
B S Pruthvishree, O R Vinodh Kumar, D K Sinha, Y P S Malik, Z Dubal, P A Desingu, M Shivakumar, Narayanan Krishnaswamy, B R Singh
AIM: A cross-sectional study was conducted in ten government organized pig farms between 2014 and 2016 representing seven states of India to understand the epidemiology of carbapenem resistance in Escherichia coli isolates. METHODS AND RESULTS: In this study, 673 fecal samples both from non- diarhhoeic (n=501) and diarrhoeic (n=172) piglets were processed for isolation of carbapenem resistant E. coli. Wherein, 112 confirmed E. coli isolates were further subjected for genotypic confirmation of carbapenem resistance and virulence factors...
March 27, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28344395/characterization-of-salmonella-gallinarum-from-an-outbreak-in-raigarh-chhattisgarh
#4
Chandrahas Sannat, Anil Patyal, Nidhi Rawat, R C Ghosh, D K Jolhe, R K Shende, S D Hirpurkar, Sanjay Shakya
AIM: The present investigation was conducted to isolate and characterize Salmonella Gallinarum from an outbreak of fowl typhoid in layer birds. MATERIALS AND METHODS: Clinically ill and dead layer birds from an outbreak were investigated. History, clinical signs, and postmortem lesions were suggestive of fowl typhoid. Postmortem samples including heart blood, intestinal contents, pieces of ovary, and liver were collected and processed immediately for bacterial culture, serotyping and antibiotic sensitivity tests...
February 2017: Veterinary World
https://www.readbyqxmd.com/read/28341979/are-third-generation-cephalosporins-unavoidable-for-empirical-therapy-of-community-acquired-pneumonia-in-adult-patients-who-require-icu-admission-a-retrospective-study
#5
Geoffroy Hariri, Jacques Tankovic, Pierre-Yves Boëlle, Vincent Dubée, Guillaume Leblanc, Claire Pichereau, Simon Bourcier, Naike Bigé, Jean-Luc Baudel, Arnaud Galbois, Hafid Ait-Oufella, Eric Maury
BACKGROUND: Third-generation cephalosporins (3GCs) are recommended for empirical antibiotic therapy of community-acquired pneumonia (CAP) in patients requiring ICU admission. However, their extensive use could promote the emergence of extended-spectrum beta-lactamases-producing Enterobacteriaceae. Our aim was to assess whether the use of 3GCs in patients with CAP requiring ICU admission was justified. METHODS: We assessed all patients with CAP who required ICU admission during a 7-year period...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28331866/clinical-response-and-outcome-in-patients-with-multidrug-resistant-gram-negative-infections
#6
Masoume Malekolkottab, Lida Shojaei, Hossein Khalili, Mahsa Doomanlou
OBJECTIVE: In this study, frequency and antimicrobial sensitivity pattern of multidrug resistant (MDR) microorganisms were evaluated in a referral teaching hospital in Iran. METHODS: Patients with MDR Gram-negative pathogens were followed during the course of hospitalization. Demographic data, baseline diseases, type of biological sample, isolated microorganism, type of infection, antibiotic regimen before the availability of the culture result and change in the antibiotic regimen following receiving the antibiogram results, response to the treatment regimen, and duration of hospitalization and patient's outcome were considered variables for each recruited patient...
January 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28323856/risk-factors-for-esbl-producing-escherichia-coli-on-pig-farms-a-longitudinal-study-in-the-context-of-reduced-use-of-antimicrobials
#7
Wietske Dohmen, Alejandro Dorado-García, Marc J M Bonten, Jaap A Wagenaar, Dik Mevius, Dick J J Heederik
The presence of extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-E. coli) in food animals is a public health concern. This study aimed to determine prevalence of ESBL-E. coli on pig farms and to assess the effect of reducing veterinary antimicrobial use (AMU) and farm management practices on ESBL-E. coli occurrence on pig farms. During 2011-2013, 36 Dutch conventional pig farms participated in a longitudinal study (4 sampling times in 18 months). Rectal swabs were taken from 60 pigs per farm and pooled per 6 pigs within the same age category...
2017: PloS One
https://www.readbyqxmd.com/read/28320357/outcome-of-neurological-early-rehabilitation-patients-carrying-multi-drug-resistant-bacteria-results-from-a-german-multi-center-study
#8
J D Rollnik, M Bertram, C Bucka, M Hartwich, M Jöbges, G Ketter, B Leineweber, M Mertl-Rötzer, D A Nowak, T Platz, K Scheidtmann, R Thomas, F von Rosen, C W Wallesch, H Woldag, P Peschel, J Mehrholz, M Pohl
BACKGROUND: Colonization or infection with multi-drug resistant (MDR) bacteria is considered detrimental to the outcome of neurological and neurosurgical early rehabilitation patients. METHODS: In a German multi-center study, 754 neurological early rehabilitation patients were enrolled and and reviewed in respect to MDR status, length of stay (LOS) and the following outcome variables: Barthel Index (BI), Early Rehabilitation Index (ERI), Glasgow Outcome Score Extended (GOSE), Coma Remission Scale (CRS), Functional Ambulation Categories (FAC)...
March 20, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28315144/monitoring-antimicrobial-resistance-amr-using-cusum-control-charts
#9
L Righi, R Amarsy, M-Q Picat, M Thuillier, E Cambau, L Raskine, S Chevret, R Flicoteaux
We evaluated the use of the Cumulative Summation (CUSUM) control chart methodology for detection of an excessive increase in antimicrobial-resistant (AMR) bacteria acquisition. We used administrative, clinical and bacteriological data from all 157,570 patients hospitalized for at least 48 h from January 1, 2010 to December 31, 2015 in a 654-bed university teaching hospital in Paris, France. Monthly computed CUSUM were evaluated for the detection of out-of-control situations, defined as incidence rates of acquired AMR bacterial colonization exceeding acceptable thresholds at the hospital and ward levels (based on six selected wards) for AMR bacteria overall and Extended-spectrum beta-lactamases Enterobacteriaceae (ESBL-E) and Methicillin-resistant Staphylococcus aureus (MRSA), specifically...
March 17, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28314728/competitive-exclusion-reduces-transmission-and-excretion-of-extended-spectrum-%C3%AE-lactamase-producing-escherichia-coli-in-broilers
#10
Daniela Ceccarelli, Alieda van Essen-Zandbergen, Bregtje Smid, Kees T Veldman, Gert Jan Boender, Egil A J Fischer, Dik J Mevius, Jeanet A van der Goot
Extended-spectrum β-lactamases (ESBLs) and plasmid mediated AmpC β-lactamases (pAmpC) are enzymes able to hydrolyze a large variety of β-lactam antibiotics, including 3(rd) generation cephalosporins and monobactams. Broilers and broiler meat products can be highly contaminated with ESBL and pAmpC-producing Escherichia coli, also known as extended-spectrum cephalosporins (ESC)-resistant E. coli, and can be a source for human infections. As few data are available on interventions to reduce ESC-resistant E...
March 17, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28291103/emergence-of-extended-spectrum-beta-lactamase-producing-enterobacteriaceae-colonization-what-termites-can-teach-us-about-the-gut-microbiota
#11
Daniel A Sweeney, Andre C Kalil
No abstract text is available yet for this article.
April 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28288838/routine-ertapenem-prophylaxis-for-transrectal-ultrasound-guided-prostate-biopsy-does-not-select-for-carbapenem-resistant-organisms-a-prospective-cohort-study
#12
Maxim G Bloomfield, Matthew J Page, Alice G McLachlan, Rodney C Studd, Timothy K Blackmore
PURPOSE: Post-transrectal ultrasound-guided prostate biopsy sepsis is an increasing problem in this era of rising antibiotic resistance. Ertapenem prophylaxis has proven very effective at our institution for reducing this, however has raised local and regional antimicrobial stewardship concerns. This study investigated the possible selective effect of single dose ertapenem prophylaxis on fecal colonization with carbapenem-resistant Enterobacteriaceae. MATERIALS AND METHODS: Patients had a rectal swab taken prior to receiving pre-biopsy ertapenem prophylaxis...
March 10, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28281425/antibiotic-resistance-patterns-and-beta-lactamase-identification-in-escherichia-coli-isolated-from-young-children-in-rural-limpopo-province-south-africa-the-mal-ed-cohort
#13
A S DeFrancesco, N F Tanih, A Samie, R L Guerrant, P O Bessong
BACKGROUND: Antibiotic resistance is a growing problem worldwide. Mechanisms of resistance vary, and some can confer resistance to multiple classes of antibiotics. OBJECTIVE: To characterise the antibiotic resistance profiles of Escherichia coli isolates obtained from stool samples of young rural children exposed or unexposed to antibiotics. METHODOLOGY: The samples were collected from children aged 4 - 12 months who were participants in the Etiology, Risk Factors, and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development (MAL-ED) project at the South Africa research site...
February 27, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28276133/plasmid-mediated-resistance-to-cephalosporins-and-quinolones-in-escherichia-coli-from-american-crows-in-the-usa
#14
Ivana Jamborova, Monika Dolejska, Ludek Zurek, Andrea K Townsend, Anne B Clark, Julie C Ellis, Ivo Papousek, Alois Cizek, Ivan Literak
American crow (Corvus brachyrhynchos) feces were tested for Escherichia coli with plasmid-mediated quinolone resistance (PMQR), extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases. A total of 590 fecal samples were collected at four roosting sites in the USA and cultivated on selective media. Pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST) were performed to assess clonality. Transferability of resistance genes was studied using conjugation and transformation bioassays...
March 9, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28273621/air-exposure-as-a-possible-route-for-esbl-in-pig-farmers
#15
Wietske Dohmen, Heike Schmitt, Marc Bonten, Dick Heederik
Livestock can carry extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae, with blaCTX-M-1 being most prevalent. ESBL carriage in farmers is associated with ESBL carriage in animals, with direct animal-human contact considered as the dominant route of transmission. However, inhalation of stable air might represent another route of transmission. We, therefore, quantified presence of blaCTX-M group 1 genes (CTX-M-gr1) in dust and the association with CTX-M-gr1 carriage in pig farmers, family members and employees...
May 2017: Environmental Research
https://www.readbyqxmd.com/read/28270849/prevalence-of-extended-spectrum-beta-lactamases-producing-microorganisms-in-patients-admitted-at-krrh-southwestern-uganda
#16
Baguma Andrew, Atek Kagirita, Joel Bazira
The emergence of extended-spectrum beta-lactamase- (ESBL-) producing pathogenic bacteria at Kabale Regional Referral Hospital (KRRH), located in southwestern Uganda, is of great concern: a phenomenon that worries clinicians and other healthcare workers due to the serious threat they pose to patients. This current study aimed at determining the phenotypic detection of ESBL-producing strains of E. coli, Klebsiella sp., and Proteus sp. isolated from clinical specimens and their prevalence in patients admitted at KRRH...
2017: International Journal of Microbiology
https://www.readbyqxmd.com/read/28264656/antimicrobial-susceptibilities-of-aerobic-and-facultative-gram-negative-bacilli-isolated-from-chinese-patients-with-urinary-tract-infections-between-2010-and-2014
#17
Qiwen Yang, Hui Zhang, Yao Wang, Zhipeng Xu, Ge Zhang, Xinxin Chen, Yingchun Xu, Bin Cao, Haishen Kong, Yuxing Ni, Yunsong Yu, Ziyong Sun, Bijie Hu, Wenxiang Huang, Yong Wang, Anhua Wu, Xianju Feng, Kang Liao, Yanping Luo, Zhidong Hu, Yunzhuo Chu, Juan Lu, Jianrong Su, Bingdong Gui, Qiong Duan, Shufang Zhang, Haifeng Shao, Robert E Badal
BACKGROUND: The objective of this study was to investigate the distribution and susceptibility of aerobic and facultative Gram-negative bacilli isolated from Chinese patients with UTIs collected within 48 h (community acquired, CA) or after 48 h (hospital acquired, HA) of hospital admission. METHODS: From 2010 to 2014, the minimum inhibitory concentrations (MICs) of 12 antibiotics for 4,332 aerobic and facultative Gram-negative bacilli, sampled in 21 hospitals in 16 cities, were determined by the broth microdilution method...
March 6, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28261951/susceptibility-to-disinfectants-in-antimicrobial-resistant-and-susceptible-isolates-of-escherichia-coli-enterococcus-faecalis-and-enterococcus-faecium-from-poultry-esbl-ampc-phenotype-of-escherichia-coli-is-not-associated-with-resistance-to-a-quaternary-ammonium
#18
Nadine Wieland, Julia Boss, Sarah Lettmann, Barbara Fritz, Karin Schwaiger, Johann Bauer, Christina S Hölzel
AIMS: The spread of bacteria that are simultaneously resistant to disinfectants and antimicrobials would constitute an unsettling scenario. In order to explore an association between antimicrobial resistance and reduced susceptibility to biocides / microbicides like disinfectants in agriculture, we investigated Escherichia (E.) coli (n = 438) and enterococci (n = 120) isolated from six different flocks of the same poultry farm with known history of antimicrobial treatment. METHODS AND RESULTS: Susceptibility to disinfectants (formic acid and a quaternary ammonium compound, didecyldimethlyammoniumchloride - DDAC) was assessed by macrodilution (German Veterinary Society)...
March 6, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28258755/unexpected-common-occurrence-of-transferable-extended-spectrum-cephalosporinase-producing-escherichia-coli-in-swedish-surface-waters-used-for-drinking-water-supply
#19
Maria Egervärn, Stina Englund, Marianne Ljunge, Christer Wiberg, Maria Finn, Mats Lindblad, Stefan Börjesson
The presence of Enterobacteriaceae producing extended spectrum beta-lactamases (ESBL) or transferable AmpC beta-lactamases (pAmpC) is increasingly being reported in humans, food-producing animals and food world-wide. However, the occurrence and impact of these so-called extended spectrum cephalosporinase (ESC)-producing Enterobacteriaceae in aquatic environments are poorly documented. This study investigated the occurrence, concentrations and characteristics of ESC-producing E. coli (ESC-Ec) in samples of surface water collected at five Swedish water treatment plants that normally have relatively high prevalence and concentration of E...
February 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28258003/ctx-m-15-and-oxa-10-beta-lactamases-in-multi-drug-resistant-pseudomonas-aeruginosa-first-report-from-pakistan
#20
Waheed Ullah, Muhammad Qasim, Hazir Rahman, Saadullah Khan, Zia Ur Rehman, Nawab Ali, Noor Muhammad
BACKGROUND: Pseudomonas aeruginosa is an emerging threat to public health worldwide due to their rapid development of drug resistance including beta-lactamases. The present study was designed to investigate the incidence of β-lactamases and genotypic pattern of CTX and OXA in the clinical isolate of multidrug resistant P. aeruginosa. METHODS: In this study a total of 102 MDR P. aeruginosa isolates obtained from Lady Reading Hospital, Peshawar, Pakistan were subjected to extended spectrum beta lactamase (ESBL), metallo beta lactamase (MBL) and plasmid mediated β-lactamase (AmpC) detection using phenotypic and molecular methods...
February 28, 2017: Microbial Pathogenesis
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