Shuhei Yoshida, Isao Koshima, Hirofumi Imai, Ayano Sasaki, Yumio Fujioka, Shogo Nagamatsu, Kazunori Yokota, Mitsunobu Harima, Shuji Yamashita, Kensuke Tashiro
OBJECTIVE: Lymphedema is classified as primary or secondary according to the underlying cause. Primary lymphedema is hereditary and is considered a consequence of an inherited abnormality of the lymphatic system. Secondary lymphedema, however, is a consequence of lymphatic failure resulting from trauma, parasitic infection, or iatrogenic obstruction. Primary lymphedema is divided into three broad groups, namely, lymphedema congenita, lymphedema praecox, and lymphedema tarda. With the exception of lymphedema tarda, it is thought that age-related deterioration in lymphatic pump function is caused by oxidative stress...
June 20, 2019: Journal of Vascular Surgery. Venous and Lymphatic Disorders