Ri-Wen, Yu-Hang Yang, Tie-Ning Zhang, Chun-Feng Liu, Ni Yang
Inflammatory diseases, including infectious diseases, diabetes-related diseases, arthritis-related diseases, neurological diseases, digestive diseases, and tumor, continue to threaten human health and impose a significant financial burden despite advancements in clinical treatment. Pyroptosis, a pro-inflammatory programmed cell death pathway, plays an important role in the regulation of inflammation. Moderate pyroptosis contributes to the activation of native immunity, whereas excessive pyroptosis is associated with the occurrence and progression of inflammation...
April 11, 2024: Pharmacological Research: the Official Journal of the Italian Pharmacological Society