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https://www.readbyqxmd.com/read/28191857/auricular-acupressure-helps-alleviate-xerostomia-in-maintenance-hemodialysis-patients-a-pilot-study
#1
Guowen Yang, Shaoqin Lin, Yuchi Wu, Shangpeng Zhang, Xiuqing Wu, Xusheng Liu, Chuan Zou, Qizhan Lin
BACKGROUND: Xerostomia is one of the most common complaints in maintenance hemodialysis (MHD) patients. This problem contributes to excess fluid intake and results in poor survival outcome. Based on Traditional Chinese Medicine (TCM) theory and literature studies, the authors have been practicing auricular acupressure therapy (AAT) to help patients with xerostomia. This pilot study was conducted to demonstrate the potential of AAT for xerostomia in MHD patients. METHODS: Eligible subjects who agreed to participate in this study were recruited and provided with AAT for 4 weeks...
February 13, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28078759/bufalin-a-bufanolide-steroid-from-the-parotoid-glands-of-the-chinese-toad-inhibits-l-type-ca-2-channels-and-contractility-in-rat-ventricular-myocytes
#2
Tao Song, Xi Chu, Xuan Zhang, Qiong Tao Song, Ying Zhang, Yuanyuan Zhang, Xue Han, Jianping Zhang, Li Chu
Bufalin is a bufanolide steroid compound in Chan Su. Chan Su is a traditional Chinese medicine prepared from the dried white secretion of the auricular and skin glands of toads, and has been used as an Oriental drug. However, the effect of bufalin on cardiac function and its underlying cellular mechanisms remain unclear. Here, we explore the cellular mechanisms of bufalin on myocardial protection via the whole-cell patch-clamp recording and video-based edge detection system. Exposure to bufalin resulted in a concentrated-dependent blockade of ICa-L , with the half-maximal inhibitory concentration (IC50 ) of 60 μM and the maximal inhibitory effect of 71...
January 11, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/28063220/biological-roles-of-glial-fibrillary-acidic-protein-as-a-biomarker-in-cartilage-regenerative-medicine
#3
Sanshiro Kanazawa, Satoru Nishizawa, Tsuyoshi Takato, Kazuto Hoshi
Glial fibrillary acidic protein (GFAP) is an intermediate filament that is expressed in specifically expressed auricular chondrocytes, which are good cell sources of cartilage regenerative medicine. Although our group uses GFAP as a biomarker of matrix production in the cultured auricular chondrocytes, the biological roles of GFAP in auricular chondrocytes has remained unknown. In this study, we demonstrated the biological functions of GFAP in the human and mouse derived auricles to clarify the significance and role with the chondrocytes of GFAP in order to provide useful information for reliable and safe regenerative medicine...
January 7, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28052910/acupuncture-and-pc6-stimulation-for-the-prevention-of-postoperative-nausea-and-vomiting-in-patients-undergoing-elective-laparoscopic-resection-of-colorectal-cancer-a-study-protocol-for-a-three-arm-randomised-pilot-trial
#4
Kun Hyung Kim, Dae Hun Kim, Ji Min Bae, Gyung Mo Son, Kyung Hee Kim, Seung Pyo Hong, Gi Young Yang, Hee Young Kim
INTRODUCTION: This study aims to assess the feasibility of acupuncture and a Pericardium 6 (PC6) wristband as an add-on intervention of antiemetic medication for the prevention of postoperative nausea and vomiting (PONV) in patients undergoing elective laparoscopic colorectal cancer resection. METHODS AND ANALYSIS: A total of 60 participants who are scheduled to undergo elective laparoscopic resection of colorectal cancer will be recruited. An enhanced recovery after surgery protocol using standardised antiemetic medication will be provided for all participants...
January 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28032171/iatrogenic-through-and-through-conchal-defect-secondary-to-auricular-cartilage-graft
#5
Hyung-Suk Ro, Si-Gyun Roh, Jin Yong Shin, Nae-Ho Lee, Kyung-Moo Yang
BACKGROUND: Over the past few years, conchal cartilage has been most often used in rhinoplasty. The donor site complications following conchal cartilage graft harvesting are scar formation, hematoma formation, and delayed wound healing, although hematoma is one of the most important and common complications. A complete conchal defect as a complication of auricular cartilage graft harvesting has not been previously reported in the literature. The authors report an unusual case of an iatrogenic conchal defect resulting from conchal cartilage graft harvesting that was treated using a posterior auricular island flap...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28032165/an-alternative-posterosuperior-auricular-fascia-flap-for-ear-elevation-during-microtia-reconstruction
#6
Yiyuan Li, Ruhong Zhang, Qun Zhang, Zhicheng Xu, Feng Xu, Datao Li
BACKGROUND: Advances in staged total auricular reconstruction have resulted in improved anterior auricular appearance; however, satisfactory postreconstruction esthetics of the retroauricular fold remain challenging. The postauricular appearance of the reconstructed ear depends largely upon optimizing the covering material. When used as the covering soft tissue for ear elevation, a flap containing primarily the upper portion of the retroauricular fascia has potential advantages over the conventional book cover-type retroauricular fascia flap...
December 28, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/27968883/auriculotherapy-for-lower-urinary-tract-symptoms-in-older-men-a-4-week-randomised-controlled-pilot-study
#7
Lorna Suen, Wai Hon, Kai Wang Yeung, Chao Hsing Yeh, Hon Fat Wong
BACKGROUND: Lower urinary tract symptoms, which commonly occur among older men, include urinary retention, voiding difficulty, frequent feeling of urinary urgency, and nocturia. Auriculotherapy, a Chinese medicine approach, is a therapeutic method in which specific points in the auricle are stimulated to achieve specific therapeutic purposes. This randomised controlled pilot study aimed to determine whether magneto-auriculotherapy alone or in combination with laser auriculotherapy is more effective than placebo for symptom relief and enhancement of quality of life...
October 2016: Lancet
https://www.readbyqxmd.com/read/27601311/battlefield-acupuncture-opening-the-door-for-acupuncture-in-department-of-defense-veteran-s-administration-health-care
#8
Patricia Hinton Walker, Arnyce Pock, Catherine G Ling, Kyung Nancy Kwon, Megan Vaughan
Battlefield acupuncture is a unique auricular acupuncture procedure which is being used in a number of military medical facilities throughout the Department of Defense (DoD). It has been used with anecdotal published positive impact with warriors experiencing polytrauma, post-traumatic stress disorder, and traumatic brain injury. It has also been effectively used to treat warriors with muscle and back pain from carrying heavy combat equipment in austere environments. This article highlights the history within the DoD related to the need for nonpharmacologic/opioid pain management across the continuum of care from combat situations, during evacuation, and throughout recovery and rehabilitation...
September 2016: Nursing Outlook
https://www.readbyqxmd.com/read/27484467/inflammatory-bowel-disease-mimicking-granulomatosis-with-polyangiitis-a-case-report
#9
Samantha C Shapiro, Armen Khararjian, Rebecca L Manno
BACKGROUND: We report a case in which the extraintestinal manifestations of inflammatory bowel disease preceded development of gastrointestinal symptoms by nearly 9 months in the context of an unusual autoantibody panel, mimicking granulomatosis with polyangiitis. This case highlights the intricacies and overlap of autoimmune diseases, and illustrates an interesting clinical phenotype: cytoplasmic anti-neutrophil cytoplasmic antibody positive inflammatory bowel disease with predominantly extraintestinal manifestations...
August 2, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27449339/hydrogels-derived-from-cartilage-matrices-promote-induction-of-human-mesenchymal-stem-cell-chondrogenic-differentiation
#10
Olivia A Burnsed, Zvi Schwartz, Katherine O Marchand, Sharon L Hyzy, René Olivares-Navarrete, Barbara D Boyan
UNLABELLED: Limited supplies of healthy autologous or allogeneic cartilage sources have inspired a growing interest in xenogeneic cartilage matrices as biological scaffolds for cartilage tissue engineering. The objectives of this study were to determine if shark and pig cartilage extracellular matrix (ECM) hydrogels can stimulate chondrocytic differentiation of mesenchymal stem cells (MSCs) without exogenous growth factors and to determine if the soluble factors retained by these ECM hydrogels are responsible...
October 1, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27266506/efficacy-and-safety-of-auricular-point-acupressure-treatment-for-gastrointestinal-dysfunction-after-laparoscopic-cholecystectomy-study-protocol-for-a-randomized-controlled-trial
#11
Yuhua Tan, Ye Zhao, Tian He, Yueshen Ma, Wang Cai, Yandong Wang
BACKGROUND: Practitioners of traditional Chinese medicine know that auricular point acupressure (APP) using vaccaria seeds on the large intestine point (CO7) has a significant effect on postoperative gastrointestinal dysfunction. A standardized, clinical, research design will transform this clinical experience into scientific evidence, thus providing a basis to promote the wider use of this therapy. We aim to carry out a double-blind, randomized, controlled trial (RCT) to evaluate the efficacy and safety of APP treatment for gastrointestinal dysfunction after laparoscopic cholecystectomy...
2016: Trials
https://www.readbyqxmd.com/read/27158365/isolation-identification-and-comparison-of-cartilage-stem-progenitor-cells-from-auricular-cartilage-and-perichondrium
#12
Ke Xue, Xiaodie Zhang, Lin Qi, Jia Zhou, Kai Liu
Auricular cartilage loss or defect remains a challenge to plastic surgeons, and cartilage regenerative medicine provides a novel method to solve the problem. However, ideal seeding cells seem to be the key point in the development of cartilage regeneration. Although bone marrow-mesenchymal stem cells were considered as the ideal seeding cells in cartilage regeneration, regenerative cartilage differentiated from bone marrow-mesenchymal stem cells still faces some problems. It is reported that many tissues and organs contain a certain number of adult progenitor or stem cells that can replace cells that die or restore tissues and organs after injury...
2016: American Journal of Translational Research
https://www.readbyqxmd.com/read/27127316/anti-inflammatory-effect-of-aqueous-extracts-of-spent-pleurotus-ostreatus-substrates-in-mouse-ears-treated-with-12-o-tetradecanoylphorbol-13-acetate
#13
Nallely Rivero-Pérez, Maricela Ayala-Martínez, Armando Zepeda-Bastida, Marcos Meneses-Mayo, Deyanira Ojeda-Ramírez
AIMS: To evaluate the application of spent Pleurotus ostreatus substrates, enriched or not with medicinal herbs, as a source of anti-inflammatory compounds. SUBJECTS AND METHODS: P. ostreatus was cultivated on five different substrates: Barley straw (BS) and BS combined 80:20 with medicinal herbs (Chenopodium ambrosioides L. [BS/CA], Rosmarinus officinalis L. [BS/RO], Litsea glaucescens Kunth [BS/LG], and Tagetes lucida Cav. [BS/TL]). The anti-inflammatory activity of aqueous extracts of spent mushroom substrates (SMSs) (4 mg/ear) was studied using an acute inflammation model in the mouse ear induced with 2...
March 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/27118463/an-islanded-rabbit-auricular-skin-flap-model-of-hyaluronic-acid-injection-induced-embolism
#14
Yan Zhuang, Mingyong Yang, Chunjun Liu
BACKGROUND: Hyaluronic acid (HA) injection-induced embolism is a rare but severe complication. This article is aimed to introduce an islanded rabbit auricular skin flap model of HA injection-induced embolism and to study its pathophysiological progress. METHODS: An islanded skin flap was elevated based on the proximal central auricular artery/vein. Eighteen rabbits were randomized into three groups. Ten, twenty, and forty microliters of HA were injected into the central auricular artery in each group, respectively...
June 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/26916676/t2-and-apparent-diffusion-coefficient-of-mri-reflect-maturation-of-tissue-engineered-auricular-cartilage-subcutaneously-transplanted-in-rats
#15
Yuko Fujihara, Naotaka Nitta, Masaki Misawa, Koji Hyodo, Yoshio Shirasaki, Kazuhiko Hayashi, Ryo Kosaka, Kazuhiro Homma, Tomokazu Numano, Shouta Kuribayashi, Yasushi Watanabe, Jiro Sato, Kuni Ohtomo, Tsuyoshi Takato, Kazuto Hoshi
In cartilage regenerative medicine, autologous chondrocyte implantation (ACI) has been applied clinically for partial defects of joint cartilage or nasal augmentation. To make treatment with ACI more effective and prevalent, modalities to evaluate the quality of transplanted constructs noninvasively are necessary. In this study, we compared the efficacy of several noninvasive modalities for evaluating the maturation of tissue-engineered auricular cartilage containing a biodegradable polymer scaffold. We first transplanted tissue-engineered cartilage consisting of human auricular chondrocytes, atelocollagen gel, and a poly-l-lactic acid (PLLA) porous scaffold subcutaneously into the back of athymic nude rats...
May 2016: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/26869339/auricular-acupuncture-for-spinal-cord-injury-related-neuropathic-pain-a-pilot-controlled-clinical-trial
#16
Irene Estores, Kevin Chen, Brian Jackson, Lixing Lao, Peter H Gorman
OBJECTIVE: To obtain preliminary data on the effects of an auricular acupuncture protocol, Battlefield Acupuncture (BFA), on self-reported pain intensity in persons with chronic Spinal Cord Injury (SCI) and neuropathic pain. DESIGN: Pilot randomized delayed entry single center crossover clinical trial at an outpatient rehabilitation and integrative medicine hospital center. METHODS: Chronic (> one year post injury) ASIA impairment scale A through D individuals with SCI with injury level from C3 through T12 and below level neuropathic pain with at least five on the Numeric Rating Scale (NRS) were recruited...
February 15, 2016: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/26839867/reconstructive-surgery-of-auricular-defects-an-overview
#17
REVIEW
Ali Ebrahimi, Alireza Kazemi, Hamid Reza Rasouli, Maryam Kazemi, Mohammad Hosein Kalantar Motamedi
CONTEXT: Despite the ongoing advances in surgical procedures and promising progress in bioengineering techniques, auricular reconstruction remains a significant challenge in plastic surgery. There are different causes for acquired auricular defects, including trauma, tumor ablation and burns. The management options for upper, middle and lower third auricular defects are briefly reviewed in the current paper. EVIDENCE ACQUISITION: Original research papers investigating the plastic surgeons, otolaryngologists and maxillofacial surgeons in approaching the complicated issue of auricular reconstruction published from January 1995 to December 2014 were aggregated and used in the current study...
November 2015: Trauma Monthly
https://www.readbyqxmd.com/read/26835562/pilot-evaluation-of-auricular-acupressure-in-end-stage-lung-cancer-patients
#18
Roger A Strong, Jane M Georges, Cynthia D Connelly
BACKGROUND: Dyspnea is a common symptom in end-stage lung cancer patients and is only infrequently controlled. Currently, the use of complimentary therapies using traditional Chinese medicine (TCM), including auricular application of Vaccaria segetalis (a small seed), is understudied. Acupressure using auricular Vaccaria segetalis application has been reported as effective in reducing dyspnea when applied to a specific area of the ear associated with lung function in the TCM paradigm...
May 2016: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/26827543/-the-antalgic-and-antiphiogistic-function-and-mechanism-of-rgdt-plaster
#19
Xiao-Xia Liu, Zhi-wang Wang, Xiao-pin Chien, Cai-min Liu, Hai-yan Tuo
OBJECTIVE: To study the antalgic and antiphlogistic functions and mechanism of ronggudingtong (RGDT) plaster (traditional Chinese medicine). METHODS: The painful models were established with hot plate test or acetic acid writhing and the inflammatory models were established with daubing dimethylbenzene on auricle or injecting formaldehyde in toe or synovial envelope to study the antalgic and antiphlogistic functions of RGDT Plaster. The total protein and leukotriene B4(LTB4) in inflammatory exudate were detected to investigate the antalgic and antiphlogistic mechanism of RGDT plaster...
September 2015: Chinese Journal of Applied Physiology
https://www.readbyqxmd.com/read/26822227/combining-regenerative-medicine-strategies-to-provide-durable-reconstructive-options-auricular-cartilage-tissue-engineering
#20
REVIEW
Zita M Jessop, Muhammad Javed, Iris A Otto, Emman J Combellack, Siân Morgan, Corstiaan C Breugem, Charles W Archer, Ilyas M Khan, William C Lineaweaver, Moshe Kon, Jos Malda, Iain S Whitaker
Recent advances in regenerative medicine place us in a unique position to improve the quality of engineered tissue. We use auricular cartilage as an exemplar to illustrate how the use of tissue-specific adult stem cells, assembly through additive manufacturing and improved understanding of postnatal tissue maturation will allow us to more accurately replicate native tissue anisotropy. This review highlights the limitations of autologous auricular reconstruction, including donor site morbidity, technical considerations and long-term complications...
January 28, 2016: Stem Cell Research & Therapy
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