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Rheumatoid artrits

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https://www.readbyqxmd.com/read/27556964/treatment-persistence-in-patients-with-rheumatoid-arthritis-and-ankylosing-spondylitis
#1
Marina Amaral de Ávila Machado, Cristiano Soares de Moura, Felipe Ferré, Sasha Bernatsky, Elham Rahme, Francisco de Assis Acurcio
OBJECTIVE: To evaluate treatment persistence in patients with rheumatoid arthritis and ankylosing spondylitis who started therapies with disease-modifying antirheumatic drugs (DMARD) and tumor necrosis factor blockers (anti-TNF drugs). METHODS: This retrospective cohort study from July 2008 to September 2013 evaluated therapy persistence, which is defined as the period between the start of treatment until it is discontinued, allowing for an interval of up to 30 days between the prescription end and the start of the next prescription...
August 22, 2016: Revista de Saúde Pública
https://www.readbyqxmd.com/read/23380023/remission-in-early-aggressive-rheumatoid-arthritis-a-multicentre-prospective-observational-italian-study-arpa-artrite-reumatoide-precoce-aggressiva
#2
MULTICENTER STUDY
Fulvia Ceccarelli, Carlo Perricone, Francesco Trotta, Giovanna Cuomo, Raffaele Pellerito, Gianfilippo Bagnato, Fausto Salaffi, Roberto Caporali, Maurizio Cutolo, Mauro Galeazzi, Ugo Fiocco, Giovanni Lapadula, Stefano Bombardieri, Girolamo Bianchi, Roberto Gorla, Anna Rita Giardina, Gaia Gallo, Angela Maria Giardino, Guido Valesini
OBJECTIVES: To provide a survey of disease activity in patients treated with standard care in Italian clinical practice. METHODS: This was an observational prospective cohort study in patients with early, aggressive rheumatoid arthritis (RA; duration ≤2 years but ≥6 weeks; DAS28 >3.2) naïve to anti-tumour necrosis factor (TNF) therapy who were treated with disease-modifying anti-rheumatic drugs (DMARDs) and/or biologics according to standard practice at 15 Italian ARPA (Artrite Reumatoide Precoce Aggressiva) centres...
May 2013: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/22472930/-practical-guide-for-the-use-of-biological-agents-in-rheumatoid-arthritis-december-2011-update
#3
Ana Filipa Mourão, João Eurico Fonseca, Helena Canhão, Maria José Santos, Alexandra Bernardo, Ana Cordeiro, Ana Rita Cravo, Ana Ribeiro, Ana Teixeira, Anabela Barcelos, Armando Malcata, Augusto Faustino, Cátia Duarte, Célia Ribeiro, Dolores Nour, Domingos Araújo, Elsa Sousa, Eva Mariz, Filipa Ramos, Filipe Vinagre, Francisco Simões Ventura, Graça Sequeira, Helena Santos, Jaime Cunha Branco, J A Gomes, J A Silva, João Ramos, Jorge Espírito Santo, José António Costa, J A Silva, José Saraiva Ribeiro, Luís Inês, Luís Miranda, Luzia Sampaio, Maria Lúcia Costa, Mário Rodrigues, Maria Carmo Afonso, Maria Inês Cunha, Maria João Saavedra, Mário Viana Queiroz, Maura Couto, Miguel Bernardes, Mónica Bogas, Patrícia Pinto, Paula Valente, Paulo Coelho, Pedro Abreu, Sara Cortes, Sofia Pimenta, Sofia Ramiro, Ricardo Figueira, Teresa Nóvoa
The authors review the practical aspects of biological therapy use for rheumatoid arthritis patients, commenting safety issues before and after treatment initiation and the best treatment strategies to optimize efficacy.
October 2011: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/20505635/portuguese-guidelines-for-the-use-of-biological-agents-in-rheumatoid-arthritis-march-2010-update
#4
João Eurico Fonseca, Helena Canhão, Paulo Reis, Maria José Santos, Jaime Branco, Alberto Quintal, Armando Malcata, Domingos Araújo, Francisco Ventura, Guilherme Figueiredo, José Canas da Silva, José Vaz Patto, Mário Viana de Queiroz, Rui André Santos, Adriano José Neto, Alves de de Matos, Ana Rodrigues, Ana Filipa Mourão, Ana Sofia Ribeiro, Ana Rita Cravo, Anabela Barcelos, Anabela Cardoso, António Vilar, Arecili Braña, Augusto Faustino, Candida Silva, Fátima Godinho, Inês Cunha, José António Costa, José António Melo Gomes, José António Araújo Pinto, J A Pereira da Silva, Luís Cunha Miranda, Luís Inês, Luís Maurício Santos, Margarida Cruz, Maria João Salvador, Maria Júlia Ferreira, Maria Rial, Miguel Bernardes, Mónica Bogas, Paula Araújo, Pedro Machado, Patrícia Pinto, Rui Gomes de Melo, Sara Cortes, Sérgio Alcino, Susana Capela
The authors present the revised version of the Portuguese Society of Rheumatology (SPR) guidelines for the treatment of rheumatoid arthritis (RA) with biological therapies. In these guidelines the criteria for introduction and maintenance of biological agents are discussed as well as the contraindications and procedures in the case of non-responders. Biological treatment should be considered in RA patients with a disease activity score 28 (DAS 28) superior to 3.2 despite treatment with 20mg/week of methotrexate (MTX) for at least 3 months or, if such treatment is not possible, after 6 months of other conventional disease modifying drug or combination therapy...
January 2010: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/19727050/-practical-guide-for-the-use-of-biotechnological-therapies-in-rheumatoid-arthritis
#5
João Eurico Fonseca, J A Canas Silva, Helena Canhão, Maria José Santos, Anabela Barcelos, Luis Inês, Maria Lucia Costa, Mário Rodrigues, Alexandra Bernardo, Ana Cordeiro, Ana Rita Cravo, Ana Ribeiro, Ana Teixeira, Armando Malcata, Augusto Faustino, Célia Ribeiro, Dolores Nour, Domingos Araújo, Elsa Sousa, Eva Mariz, Filipa Ramos, Filipe Vinagre, Francisco Simões Ventura, Graça Sequeira, Helena Santos, Jaime Cunha Branco, João Ramos, Jorge Espírito Santo, José António Costa, J A Pereira da Silva, Luis Miranda, Luzia Sampaio, Maria Carmo Afonso, Maria João Saavedra, Maria Inês Cunha, Mário Viana Queiroz, Maura Couto, Patrícia Pinto, Paula Valente, Pedro Abreu, Ricardo Ornelas Figueira, Sofia Ramiro, Teresa Nóvoa, Miguel Bernardes
No abstract text is available yet for this article.
April 2009: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/18050379/the-italian-registry-of-aggressive-rheumatoid-arthritis-the-giara-project
#6
Antonio Marchesoni, Marcello Govoni, Gabriele Valentini, Guido Valesini, Fausto Salaffi, Pierluigi Macchioni, Ornella Della Casa Alberighi, Gianfranco Ferraccioli et al.
OBJECTIVE: In 1999, the Italian Society of Rheumatology started a project to determine the prevalence and clinical characteristics of aggressive rheumatoid arthritis (ARA). METHODS: For 1 year, all patients with RA for > 5 years and referred to participating centers were entered in a registry and classified as having ARA if they fulfilled the following criteria: 10 swollen joints for at least 6 weeks, positive rheumatoid factor (RF), and at least one bone erosion (if disease duration of 2 years); (a) RF-positive and having 10 swollen joints or at least one newly eroded joint, or (b) if RF-negative, having 10 swollen joints and at least one newly eroded joint (if disease duration > 2 to < 5 years)...
December 2007: Journal of Rheumatology
https://www.readbyqxmd.com/read/18031101/risks-and-benefits-of-low-dosage-cyclosporin-in-rheumatoid-arthritis
#7
G Pasero, G F Ferraccioli, I Portioli
The effects of cyclosporin on the activity of rheumatoid arthritis have mainly been investigated in patients with active, refractory, long-standing disease. The data obtained in these trials suggest that cyclosporin is not only a symptomatic treatment for rheumatoid arthritis but can also be considered a disease-modifying antirheumatic drug (DMARD), since it seems to be capable of slowing the progression of cartilage and bone damage due to rheumatoid arthritis. The trials conducted so far have led to a better understanding of cyclosporin toxicity and, therefore, to better monitoring of patients in order to avoid it...
May 1997: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://www.readbyqxmd.com/read/17450763/-guidelines-for-the-use-of-biologic-therapies-in-rheumatoid-arthritis-december-2006-update
#8
(no author information available yet)
The authors present the revised version of the Portuguese Society of Rheumatology (SPR) guidelines for the treatment of rheumatoid arthritis (RA) with biological therapies. In these guidelines the criteria for introduction and maintenance of biological therapies were discussed as well as the contra-indications and procedures in case of non-responders. Biological treatment is indicated in RA patients with a disease activity score 28 (DAS 28) superior to 3,2 despite treatment with 20mg/week of methotrexate (MTX) for at least 3 months or, if such treatment is not possible, refractory to 6 months of other conventional disease modifying drug or combination therapy...
January 2007: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/17094336/-tuberculosis-in-rheumatic-patients-treated-with-tumour-necrosis-factor-alpha-antagonists-the-portuguese-experience
#9
João Eurico Fonseca, Helena Canhão, Cândida Silva, Cláudia Miguel, Maria Jesus Mediavilla, Ana Teixeira, Walter Castelão, Patrícia Nero, Miguel Bernardes, Alexandra Bernardo, Eva Mariz, Fátima Godinho, Maria José Santos, Mónica Bogas, Margarida Oliveira, Maria João Saavedra, Anabela Barcelos, Margarida Cruz, Rui André Santos, Luís Maurício, Mário Rodrigues, Guilherme Figueiredo, Alberto Quintal, José Vaz Patto, Armando Malcata, José Canas da Silva, Domingos Araújo, Francisco Ventura, Jaime Branco, Mário Viana Queiroz
In Portugal, 13 cases of tuberculosis (TB) were reported, in the period between 1999 and 2005, in 960 patients exposed to anti-TNFalpha treatment (1.35%), 8 females and 5 males. Mean age was 46.7 +/- 13.8 years. 9 patients had rheumatoid arthritis (RA), in 639 exposed patients (1.4%), 3 had ankylosing spondylitis (AS), in 200 exposed patients (1.5%) and 1 had psoriatic arthritis (PA), in 101 exposed patients (1%). The anti-TNFa used was in 8 cases infliximab (in 456 patients exposed, 1.5%), in 4 adalimumab (in 171 patients exposed, 2...
July 2006: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/17094335/-recommendations-for-the-diagnosis-and-treatment-of-latent-and-active-tuberculosis-in-patients-with-inflammatory-joint-diseases-treated-with-tumour-necrosis-factor-alpha-inhibitors
#10
João Eurico Fonseca, Helena Lucas, Helena Canhão, Raquel Duarte, Maria José Santos, Miguel Villar, Augusto Faustino, Elena Raymundo
The Portuguese Society of Rheumatology (SPR) and the Portuguese Society of Pulmonology (SPP) have developed guidelines for the diagnosis and treatment of latent tuberculosis infection (LTBI) and active tuberculosis (AT) in patients with inflammatory joint diseases (IJD), namely rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis, treated with tumour necrosis factor alpha (TNF-alpha) antagonists. Due to the high risk of tuberculosis (TB) in patients with IJD, LTBI and AT screening should be performed as soon as possible, ideally at the moment of IJD diagnosis...
July 2006: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/14969064/aggressive-rheumatoid-arthritis-registry-in-italy-characteristics-of-the-early-rheumatoid-arthritis-subtype-among-patients-classified-according-to-the-acr-criteria
#11
REVIEW
(no author information available yet)
The Italian Society of Rheumatology in the year 2000 decided to sponsor the creation of a data base (Registry) of consecutive patients who fulfilled the diagnosis of rheumatoid arthritis (RA) according to the American College of Rheumatology (ACR) criteria. The registry is designed to collect data on the "aggressive" type of RA all over the country in order to determine the percentage of patients who satisfy the established criteria among incident cases of RA and to define the therapeutic approach according to the characteristics of the enrolled patients...
September 2003: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/9389222/clinical-trials-in-rheumatoid-arthritis-methodological-suggestions-for-assessing-radiographs-arising-from-the-grisar-study-gruppo-reumatologi-italiani-studio-artrite-reumatoide
#12
COMPARATIVE STUDY
R Ferrara, F Priolo, M Cammisa, L Bacarini, A Cerase, G Pasero, G F Ferraccioli, O D Alberighi, A Antonellini, E Marubini
OBJECTIVES: The three x ray assessors of the GRISAR study (blinded to treatment) gave consensual erosion and damage scores to the baseline and 12 month radiographs of 284 rheumatoid arthritis (RA) patients using three different methods: single readings (blinded as to patient and chronological sequence of the x rays), paired readings (blinded as to sequence), and chronologically ordered paired readings. The aim was to evaluate which of these reading procedures is the most appropriate for clinical trials...
October 1997: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/9375868/radiographic-changes-in-the-feet-of-patients-with-early-rheumatoid-arthritis-grisar-gruppo-reumatologi-italiani-studio-artrite-reumatoide
#13
RANDOMIZED CONTROLLED TRIAL
F Priolo, L Bacarini, M Cammisa, A Cerase, R Ferrara, O Della Casa-Alberighi
OBJECTIVE: To assess the value of radiographs of the feet of patients with early rheumatoid arthritis (RA) in the evaluation of RA classification and outcome. METHODS: Within a multicenter therapeutic trial, baseline and 12 month radiographs of the hands, wrists, and feet of 284 patients with early RA (< or = 4 years; mean 1.4; median 0.6) were scored according to a modified Larsen-Dale method by an independent radiological reading committee, blinded to the treatment, clinical, and laboratory data...
November 1997: Journal of Rheumatology
https://www.readbyqxmd.com/read/8810684/is-the-control-of-disease-progression-within-our-grasp-review-of-the-grisar-study-gruppo-reumatologi-italiani-studio-artrite-reumatoide
#14
RANDOMIZED CONTROLLED TRIAL
G F Ferraccioli, O Della Casa-Alberighi, E Marubini, F Priolo, A Mathieu, F Fantini, M Cutolo, G Pasero
A prospective, open, multicentre, randomized study with a blinded radiological end-point was started in 1991. The aim of the study was to assess whether cyclosporin A (CyA) controls ongoing anatomical damage in active early rheumatoid arthritis (RA) better than conventional disease-modifying anti-rheumatic drugs (DMARDs) as used in everyday clinical practice. A total of 340 consenting patients with early RA (mean duration 1.4 yr) were recruited; 167 were randomized to CyA 3mg/kg per day and 173 to DMARDs. Hand, wrist and foot X-rays were blindly scored by a central committee of three radiologists using the Larsen-Dale method...
September 1996: British Journal of Rheumatology
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