Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#21
JOURNAL ARTICLE
Caroline E Anderson, Rodney D Gilbert, Matthew Harmer, Patrick Ritz, Stephen Wootton, Marinos Elia
OBJECTIVE: Malnutrition and obesity are complex burdensome challenges in paediatric chronic kidney disease (CKD) management that can adversely affect growth, disease progression, wellbeing, and response to treatment. Total energy expenditure (TEE) and energy requirements in children are essential for growth outcomes but are poorly defined, leaving clinical practice varied and insecure. The aims of this study were to explore a practical approach to guide prescribed nutritional interventions, using measurements of TEE, physical activity energy expenditure (PAEE), and their relationship to kidney function...
July 18, 2023: Journal of Renal Nutrition
#22
JOURNAL ARTICLE
Thomas N Nissen, Catherine Rechnitzer, Birgitte K Albertsen, Lotte Borgwardt, Vibeke B Christensen, Eva Fallentin, Henrik Hasle, Lars S Johansen, Lisa L Maroun, Karin B Nissen, Allan Rasmussen, Mathias Rathe, Steen Rosthøj, Nicolai A Schultz, Peder S Wehner, Marianne H Jørgensen, Jesper Brok
BACKGROUND: Malignant liver tumours in children are rare and national outcomes for this tumour entity are rarely published. This study mapped paediatric liver tumours in Denmark over 35 years and reported on the incidence, outcomes and long-term adverse events. METHODS: We identified all liver tumours from the Danish Childhood Cancer Registry and reviewed the case records for patient and tumour characteristics, treatment and clinical outcome. RESULTS: We included 79 patients in the analyses...
June 26, 2023: Cancers
#23
JOURNAL ARTICLE
Tobias Geis, Svena Gutzeit, Sotiris Fouzas, Andreas Ambrosch, Pascal Benkert, Jens Kuhle, Sven Wellmann
BACKGROUND/OBJECTIVE: Serum neurofilament light chain (sNfL) is a specific biomarker of neuronal damage. Elevated sNfL levels have been reported in numerous neurologic diseases in adults, whereas data on sNfL in the pediatric population are incomplete. The aim of this study was to investigate sNfL levels in children with various acute and chronic neurologic disorders and describe the age dependence of sNfL from infancy to adolescence. METHODS: The total study cohort of this prospective cross-sectional study consisted of 222 children aged from 0 to 17 years...
July 2023: European Journal of Paediatric Neurology: EJPN
#24
JOURNAL ARTICLE
Raphael Schild, Simeon Dupont, Jérôme Harambat, Enrico Vidal, Ayşe Balat, Csaba Bereczki, Beata Bieniaś, Per Brandström, Francoise Broux, Silvia Consolo, Ivana Gojkovic, Jaap W Groothoff, Kristine Hommel, Holger Hubmann, Fiona E M Braddon, Tatiana E Pankratenko, Fotios Papachristou, Lucy A Plumb, Ludmila Podracka, Sylwester Prokurat, Anna Bjerre, Carolina Cordinhã, Juuso Tainio, Enkelejda Shkurti, Giuseppina Spartà, Karel Vondrak, Kitty J Jager, Jun Oh, Marjolein Bonthuis
BACKGROUND: Data on comorbidities in children on kidney replacement therapy (KRT) are scarce. Considering their high relevance for prognosis and treatment, this study aims to analyse the prevalence and implications of comorbidities in European children on KRT. METHODS: We included data from patients <20 years of age when commencing KRT from 2007 to 2017 from 22 European countries within the European Society of Paediatric Nephrology/European Renal Association Registry...
April 2023: Clinical Kidney Journal
#25
REVIEW
B Bañuelos Marco, M I Dönmez, T Geppert, T Prudhomme, R Campi, B Mesnard, V Hevia, R Boissier, A Pecoraro, A Territo
INTRODUCTION AND OBJECTIVE: Renal transplantation in the pediatric population differs from adults in many aspects. This review will focus on the unique issues of the pediatric recipient. MATERIAL AND METHODS: A narrative review on the scarce literature regarding preoperative evaluation before kidney transplantation of the paediatric recipient with an educational focus was conducted. The literature search allowed for identification of publications in English from January 2000 to October 2022...
2023: Actas urologicas españolas
#26
JOURNAL ARTICLE
Hanne Agerskov, Helle C Thiesson, Helen Schultz, Birthe D Pedersen
BACKGROUND: Paediatric kidney transplantation is often the best choice of treatment for kidney failure with replacement therapy and represents an important change in the child's well-being. There are, however, still a number of challenges in addition to the parental role. The magnitude of intensive parental caregiving and support required by children with a kidney transplant could be disruptive to family relationships and dynamics. OBJECTIVE: To explore the experiences of family relationships and dynamics among parents of a child with a kidney transplant...
March 22, 2023: Journal of Renal Care
#27
JOURNAL ARTICLE
Faezeh Sakhinia, Vicky Brice, Rebecca Ollerenshaw, Sellathurai Gajendran, Jane Ashworth, Mohan Shenoy
Tubulointerstitial nephritis and uveitis (TINU) is a rare autoimmune disorder often triggered by drugs and infections. Since the onset of the COVID-19 pandemic, we have observed an unusual cluster of paediatric cases. Four children (3 females) were diagnosed with TINU (median age 13 years) following a kidney biopsy and ophthalmologic assessment. Presenting symptoms included abdominal pain (3 cases), fatigue, weight loss and vomiting (2 cases). At presentation, median eGFR was 50.3 ml/min/1.73m2 (range 19...
February 27, 2023: Journal of Nephrology
#28
JOURNAL ARTICLE
Chenwei Wang, Wei Qu, Qiurong Chen, Wen-Yan Huang, Yulin Kang, Jian Shen
BACKGROUND: Children with primary nephrotic syndrome (PNS) who relapse after glucocorticoid therapy are shown to have a decreased total proportion of butyrate-producing bacteria in the gut at onset. Glucocorticoid treatment changes the gut microbiota composition. It is unclear whether gut microbiota at remission right after therapy and gut bacteria other than butyrate-producing bacteria are associated with PNS relapse. METHODS: PNS relapse of paediatric patients within 1 year after glucocorticoid therapy was recorded...
February 23, 2023: Nephrology, Dialysis, Transplantation
#29
JOURNAL ARTICLE
Juan José Menéndez, Amelia Caridad Sánchez-Galindo, Joan Balcells, María Ángeles Tejero-Hernández, Ángela Ferrer-Barba, Emilio Ibiza-Palacios, Constancio Medrano-López, Ferran Gran, Manuel Ángel Frías-Pérez, María García-Vieites, Ana Cano-Sánchez, Luz Polo, Juan-Miguel Gil-Jaurena, Raúl Felipe Abella, Carlos Merino-Cejas, Isaac Martínez-Bendayán, Félix Serrano, Luis García-Guereta
OBJECTIVES: To describe the use of ventricular assist devices (VAD) in children in Spain and to identify variables related to survival. METHODS: This is an observational cohort study of all children younger than 18 years of age who underwent an initial implantation of a VAD at any of the 6 paediatric heart transplant centres from May 2006 to December 2020. Subjects were identified retrospectively from each hospital's database. RESULTS: Paracorporeal VADs were implanted in 118 children [pulsatile (63%), continuous (30...
February 3, 2023: European Journal of Cardio-thoracic Surgery
#30
JOURNAL ARTICLE
Amin J Roberts, Alicia Lim, Jonathan R Bishop, Ed Gane, Elizaveta Rakhmanova, William Wong, Helen M Evans
AIM: There are increasing reports of atopy/allergy following solid organ transplantation, especially paediatric liver transplantation (LT) with minimal New Zealand (NZ) data. We describe the prevalence of transplant-acquired atopy and allergy (TAA) in NZ paediatric liver transplant recipients, compared to paediatric kidney and adult liver transplants. METHODS: TAA focussed health questionnaires were sent to patients selected from the NZ transplant registry (transplanted between January 2003 and December 2017)...
January 30, 2023: Journal of Paediatrics and Child Health
#31
JOURNAL ARTICLE
Agnieszka Prytula, Rukshana Shroff, Kai Krupka, Ellen Deschepper, Justine Bacchetta, Gema Ariceta, Atif Awan, Elisa Benetti, Anja Büscher, László Berta, Andrea Carraro, Martin Christian, Luca Dello Strologo, Katja Doerry, Sophie Haumann, Guenter Klaus, Caroline Kempf, Birgitta Kranz, Jun Oh, Lars Pape, Martin Pohl, Nikoleta Printza, Jacek Rubik, Claus Peter Schmitt, Mohan Shenoy, Giuseppina Spartà, Hagen Staude, Clodagh Sweeney, Lutz Weber, Stefanie Weber, Marcus Weitz, Dieter Haffner, Burkhard Tönshoff
INTRODUCTION: Little is known about the consequences of deranged chronic kidney disease-mineral and bone disorder (CKD-MBD) parameters on kidney allograft function in children. We examined a relationship between these parameters over time and allograft outcome. METHODS: This registry study from the Cooperative European Paediatric Renal Transplant Initiative (CERTAIN) collected data at baseline, months 1, 3, 6, 9, and 12 after transplant; and every 6 months thereafter up to 5 years...
January 2023: KI Reports
#32
REVIEW
Abigail Atlas-Lazar, Daniella Levy-Erez
PURPOSE OF REVIEW: In a child with evidence of acute kidney injury (AKI) following renal transplantation, it is important to quickly and accurately diagnose the cause to enable timely initiation of therapeutic interventions. The following article will discuss the differential diagnosis of acute graft dysfunction in paediatric kidney transplant recipients. This review will systematically guide the clinician through the common and less common causes and provide updates on current treatments...
April 1, 2023: Current Opinion in Pediatrics
#33
JOURNAL ARTICLE
Alessio Alletto, Federica Attaianese, Alessandra Montemaggi, Francesca Becherucci, Paola Romagnani, Sandra Trapani
BACKGROUND: Haemolytic uremic syndrome (HUS) is a thrombotic microangiopathy characterized by haemolytic anaemia, thrombocytopenia, and acute kidney injury. It represents the most frequent cause of acute kidney failure in paediatric age. HUS includes acquired types, such as post-infectious forms, and inherited types. If not promptly recognized, HUS still has high mortality and morbidity, with disabling long-term sequelae. METHODS: Children diagnosed with HUS hospitalized between January 2010 and July 2021 at Meyer Children's Hospital were retrospectively studied...
December 21, 2022: Nephron
#34
JOURNAL ARTICLE
Camille de Truchis, Naïm Bouazza, Frantz Foissac, Marina Charbit, Laurène Dehoux, Gabrielle Lui, Mégane Ribot, Nelly Briand, Yi Zheng, Jean-Marc Tréluyer, Olivia Boyer
AIMS: Glucocorticoids are 1 of the primary treatments in paediatric kidney transplantation. The aims of this study were: (i) to build a population pharmacokinetics (PPK) model of free prednisolone, which is the active form of prednisone, in paediatric kidney transplant recipients; (ii) to identify covariates accounting for interindividual variability (IIV) of pharmacokinetics (PK) parameters; and (iii) to investigate drug exposure-safety relationships. METHODS: Ninety-seven samples were obtained from 39 paediatric kidney transplant recipients (aged 3...
May 2023: British Journal of Clinical Pharmacology
#35
JOURNAL ARTICLE
Miguel Ángel Frutos, Marta Crespo, María de la Oliva Valentín, Ángel Alonso-Melgar, Juana Alonso, Constantino Fernández, Gorka García-Erauzkin, Esther González, Ana M González-Rinne, Lluis Guirado, Alex Gutiérrez-Dalmau, Jorge Huguet, José Luis López Del Moral, Mireia Musquera, David Paredes, Dolores Redondo, Ignacio Revuelta, Carlos J Van-der Hofstadt, Antonio Alcaraz, Ángel Alonso-Hernández, Manuel Alonso, Purificación Bernabeu, Gabriel Bernal, Alberto Breda, Mercedes Cabello, José Luis Caro-Oleas, Joan Cid, Fritz Diekmann, Laura Espinosa, Carme Facundo, Marta García, Salvador Gil-Vernet, Miquel Lozano, Beatriz Mahillo, María José Martínez, Blanca Miranda, Federico Oppenheimer, Eduard Palou, María José Pérez-Saez, Lluis Peri, Oscar Rodríguez, Carlos Santiago, Guadalupe Tabernero, Domingo Hernández, Beatriz Domínguez-Gil, Julio Pascual
This Guide for Living Donor Kidney Transplantation (LDKT) has been prepared with the sponsorship of the Spanish Society of Nephrology (SEN), the Spanish Transplant Society (SET), and the Spanish National Transplant Organization (ONT). It updates evidence to offer the best chronic renal failure treatment when a potential living donor is available. The core aim of this Guide is to supply clinicians who evaluate living donors and transplant recipients with the best decision-making tools, to optimise their outcomes...
December 2022: Nefrología
#36
JOURNAL ARTICLE
Matthias Zirngibl, Kathrin Buder, Tobias Luithle, Burkhard Tönshoff, Marcus Weitz
BACKGROUND: Vesico-ureteral reflux (VUR) is considered to be a risk factor for recurrent febrile urinary tract infections and impaired renal transplant survival. METHODS: An online survey supported by the European Society for Paediatric Nephrology was designed to evaluate current management strategies of VUR in native and transplanted kidneys of recipients aged <18 years. RESULTS: Seventy-three pediatric transplant centers from 32 countries contributed to the survey...
March 2023: Pediatric Transplantation
#37
REVIEW
Genevieve Southgate, Patrick Clarke, Matthew J Harmer
BACKGROUND: Tubulointerstitial nephritis and uveitis syndrome (TINU) is a rare condition characterised by bilateral uveitis and interstitial nephritis. There is no nationally, or internationally agreed upon treatment regimen. A systematic review was undertaken to report the renal outcomes in TINU, and treatments used. METHODS: Medline (1969-2021) and EMBASE (1988-2021) databases were searched for primary studies, clinical practice guidelines and case reports of adult and paediatric TINU cases, as defined by Mandeville criteria...
March 2023: Journal of Nephrology
#38
JOURNAL ARTICLE
Lesley Prentice-Hoogervorst, Pat M Mayers
Background: Transition of adolescents from paediatric to adult health services is an important aspect of caring for young people with chronic diseases. Successful transition of adolescents living with a transplant is critical for long-term survival into adulthood. This qualitative study explored the lived experience of adolescents in a South African setting following their planned and supported transition process. Aim: To explore the lived experience of transition for adolescents who had received a renal or liver transplant as a child, from paediatric to adult transplant services in the public health sector...
2022: Health SA, SA Gesondheid
#39
JOURNAL ARTICLE
Christian Patry, Lukas D Sauer, Anja Sander, Kai Krupka, Alexander Fichtner, Jolanda Brezinski, Yvonne Geissbühler, Elodie Aubrun, Anna Grinienko, Luca Dello Strologo, Dieter Haffner, Jun Oh, Ryszard Grenda, Lars Pape, Rezan Topaloğlu, Lutz T Weber, Antonia Bouts, Jon Jin Kim, Agnieszka Prytula, Jens König, Mohan Shenoy, Britta Höcker, Burkhard Tönshoff
BACKGROUND: Randomized controlled trials in pediatric kidney transplantation are hampered by low incidence and prevalence of kidney failure in children. Real-World Data from patient registries could facilitate the conduct of clinical trials by substituting a control cohort. However, the emulation of a control cohort by registry data in pediatric kidney transplantation has not been investigated so far. METHODS: In this multicenter comparative analysis, we emulated the control cohort (n = 54) of an RCT in pediatric kidney transplant patients (CRADLE trial; ClinicalTrials...
October 20, 2022: Pediatric Nephrology
#40
REVIEW
Sara Ugolini, Riccardo Coletta, Antonino Morabito
Paediatric Intestinal Transplantation (IT) presents the highest mortality on the waiting-list due to anatomical disproportion. Living-Donor IT (LDIT) offers the best advantages and when performed among identical monozygotic twins, it also benefits from unique immunology. According to MEDLINE/Pubmed, twin-to-twin LDIT has been performed in seven cases (6:7 males, median age of 32 years). None of the patients received immunosuppression postoperatively. Only one paediatric twinto- twin LDIT was carried out with a 160-cm mid-ileum tract: an interposed 4/5-cm arterial graft was required to ensure a tensionfree anastomosis to the anterior wall of the infra-renal abdominal aorta...
October 18, 2022: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
