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Ashwini N Kulkarni, Anuprita D Watharkar, Niraj R Rane, Byong-Hun Jeon, Sanjay P Govindwar
Navy Blue HE22 (NBHE22), dye mixture and real textile effluent were decolorized and degraded by lichen Dermatocarpon vellereceum. Up-flow bioreactor showed about 80%, 70%, 80% and 65% removal of American dye manufacturer index (ADMI), biological oxygen demand (BOD), total suspended solids (TSS) and total dissolved solids (TDS), respectively of dye mixture at flow rate of 25mlh(-1). The removal of ADMI, BOD, TSS and TDS of real textile effluent were 75%, 65%, 82% and 70%, respectively at flow rate of 30mlh(-1)...
October 10, 2017: Ecotoxicology and Environmental Safety
Yaqi Xu, Jun Wang, Lusheng Zhu, Zhongkun Du, Jinhua Wang, Kai Wei
Ionic liquids (ILs) are considered environmentally friendly solvents and are widely applied in various fields; however, some researchers have noted the toxicity of ILs to plants cultivated in nutrient solution. To evaluate the toxicities of ILs to wheat seedlings in soil, the natural growth environment of plants, a study was performed using three imidazolium-based ionic liquids with different anions: 1-octyl-3-methylimidazolium chloride ([C8mim]Cl), 1-octyl-3-methylimidazolium bromide ([C8mim]Br) and 1-octyl-3-methylimidazolium tetrafluoroborate ([C8mim]BF4)...
September 25, 2017: Chemosphere
Gustavo M Calderón-Fernández, Débora E Moriconi, Andrea B Dulbecco, M Patricia Juárez
The insect integument, formed by the cuticle and the underlying epidermis, is essential for insect fitness, regulation of lipid biosynthesis and storage, insect growth and feeding, together with development progress. Its participation in insecticide resistance has also been outlined. Triatoma infestans Klug (Hemiptera: Reduviidae) is one of the major vectors of Chagas disease in South America; however, genomic data are scarce. In this study, we performed a transcriptome analysis of the nymph integument in order to identify which genes are expressed and their putative role...
September 27, 2017: Journal of Medical Entomology
Hsin-Yang Chang, Shu-Tseng Lin, Tzu-Ping Ko, Shu-Mei Wu, Tsen-Hung Lin, Yu-Ching Chang, Kai-Fa Huang, Tse-Min Lee
Dehydroascorbate reductase (DHAR) is a key enzyme for glutathione (GSH)-dependent reduction of dehydroascorbate (DHA) to recycled ascorbate (AsA) in plants, and plays a major role against the toxicity of reactive oxygen species (ROS). Previously, we proposed that the increase of AsA regeneration via enhanced DHAR activity modulates the ascorbate-glutathione cycle activity against photooxidative stress in Chlamydomonas reinhardtii. In the present work, we use site-directed mutagenesis and crystal structure analysis to elucidate the molecular basis of how C...
October 3, 2017: Plant Physiology and Biochemistry: PPB
Muhammad Rizwan, Mohammad Golam Mostofa, Muhammad Zulfiqar Ahmad, Muhammad Imtiaz, Sajid Mehmood, Muhammad Adeel, Zhihua Dai, Zheyong Li, Omar Aziz, Yihui Zhang, Shuxin Tu
Soil contamination with nickel (Ni) is a persistent threat to crop production worldwide. The present study examined the putative roles of nitric oxide (NO) in improving Ni-tolerance in rice. Our findings showed that application of exogenous sodium nitroprusside (SNP), a NO donor, significantly improved the growth performance of rice seedlings when grown under excessive Ni. The enhanced Ni-tolerance of rice prompted by SNP could be ascribed to its ability to regulate Ni uptake, decrease Ni-induced oxidative stress as evidenced by reduced levels of hydrogen peroxide, malondialdehyde, and electrolyte leakage in Ni-stressed plants...
September 30, 2017: Chemosphere
Xiuxia Li, Haiyan Shi, Xiwu Gao, Pei Liang
BACKGROUND: Uridine diphosphate-glucuronosyltransferases (UGTs), as multifunctional detoxification enzymes, play important roles in the biotransformation of various compounds. However, their roles in insecticide resistance are still unclear. This study presents a genome-wide identification of the UGTs in diamondback moth, Plutella xylostella (L.), a worldwide notorious insect pest of cruciferous crops. The possible roles of these UGTs in insecticide resistance were evaluated. RESULTS: A total of 21 putative UGTs in P...
October 13, 2017: Pest Management Science
Mehran Zarghami, Maryam Rezapour
BACKGROUND: Loperamide is used as an antidiarrheal drug and is available over-the-counter. It cannot pass the blood-brain barrier and it does not have a considerable abuse potential. It can lead to dangerous cardiac arrhythmia. CASE REPORT: Herein, we report a 35-year-old man with a 13-year history of abusing opioids who had undergone detoxification for four times during this period. He underwent detoxification for using 200 mg loperamide daily with anticholinergic agents, clonidine, non-steroidal analgesics, and diazepam...
January 2017: Addiction & Health
Xunbing Huang, Douglas W Whitman, Jingchuan Ma, Mark Richard McNeill, Zehua Zhang
We reared Oedaleus asiaticus grasshoppers under four different single-plant diets to examine the relationships among diet, performance, stress, and transcription patterns. Grasshoppers fed only Artemisia frigida (Asteraceae) were stressed, as indicated by their lower growth, size, development, and survival, in comparison to grasshoppers fed on any of three grasses, Cleistogenes squarrosa, Leymus chinensis, or Stipa krylovii (all Poaceae). We then used transcriptome analysis to examine how gene expression levels in O...
2017: PloS One
M A Valdivia-González, W A Díaz-Vásquez, D Ruiz-León, A A Becerra, D R Aguayo, J M Pérez-Donoso, C C Vásquez
The increasing industrial utilization of tellurium has resulted in an important environmental pollution with the soluble, extremely toxic oxyanion tellurite. In this context, the use of microorganisms for detoxifying tellurite or tellurium biorecovery has gained great interest. The ability of different Shewanella strains to reduce tellurite to elemental tellurium was assessed; the results showed that the reduction process is dependent on electron transport and the ∆pH gradient. While S. baltica OS155 showed the highest tellurite resistance, S...
October 11, 2017: Archives of Microbiology
Davida M Schiff, Mari-Lynn Drainoni, Zoe M Weinstein, Lisa Chan, Megan Bair-Merritt, David Rosenbloom
BACKGROUND: The increasing rates of opioid use disorder and resulting overdose deaths are a public health emergency, yet only a fraction of individuals in need receive treatment. OBJECTIVE: To describe the implementation of and participants' experiences with a novel police-led addiction treatment referral program. METHODS: Follow-up telephone calls to participants in the Gloucester Police Department's Angel Program from June 2015-May 2016...
November 2017: Journal of Substance Abuse Treatment
Andrew Gaddis, Mary Clare Kennedy, Ekaterina Nosova, M-J Milloy, Kanna Hayashi, Evan Wood, Thomas Kerr
OBJECTIVES: Supervised injection facilities (SIFs) are increasingly being implemented worldwide in response to the harms associated with injection drug use. Although SIFs have been shown to promote engagement of people who use injection drugs (PWID) with external health services, little is known about the potential of co-locating on-site detoxification services with SIFs. The aim of this study was to characterize use of detoxification services co-located at Insite, North America's first SIF, among PWID in Vancouver, Canada...
November 2017: Journal of Substance Abuse Treatment
Qingjie Guan, Xu Liao, Mingliang He, Xiufeng Li, Zhenyu Wang, Haiyan Ma, Song Yu, Shenkui Liu
The 636-bp-long cDNA sequence of OsCu/Zn-SOD (AK059841) was cloned from Oryza sativa var. Longjing11 via reverse transcription polymerase chain reaction (RT-PCR). The encoded protein comprised of 211 amino acids is highly homologous to Cu/Zn-SOD proteins from tuscacera rice and millet. Quantitative RT-PCR revealed that in rice, the level of OsCu/Zn-SOD gene expression was lowest in roots and was highest in petals and during the S5 leaf stage. Moreover, the expression level of OsCu/Zn-SOD gene expression decreased during the L5 leaf stage to maturity...
2017: PloS One
Buyun Du, Jun Zhou, Jing Zhou
The causes of Kashin-Beck disease (KBD) in children are multifactorial, and particular consideration has been given to childhood selenium (Se) deficiency. In this study, dietary intake of Se and mercury (Hg) was determined at KBD areas to investigate the Se status and risks. Therefore, total Hg and Se levels were investigated in scalp hair samples and in daily intake food samples of 150 schoolchildren in Yongshou County of Shaanxi, China. The results showed that the average concentration of Se in children's hair has risen to 302 ng g(-1) and significantly increased compared to the data reported decades ago...
October 10, 2017: Environmental Geochemistry and Health
Christophe Antonio-Nkondjio, N Sonhafouo-Chiana, C S Ngadjeu, P Doumbe-Belisse, A Talipouo, L Djamouko-Djonkam, E Kopya, R Bamou, P Awono-Ambene, Charles S Wondji
BACKGROUND: Malaria remains a major public health threat in Cameroon and disease prevention is facing strong challenges due to the rapid expansion of insecticide resistance in vector populations. The present review presents an overview of published data on insecticide resistance in the main malaria vectors in Cameroon to assist in the elaboration of future and sustainable resistance management strategies. METHODS: A systematic search on mosquito susceptibility to insecticides and insecticide resistance in malaria vectors in Cameroon was conducted using online bibliographic databases including PubMed, Google and Google Scholar...
October 10, 2017: Parasites & Vectors
Shimpei Uraguchi, Nobuhiro Tanaka, Christian Hofmann, Kaho Abiko, Naoko Ohkama-Ohtsu, Michael Weber, Takehiro Kamiya, Yuka Sone, Ryosuke Nakamura, Yasukazu Takanezawa, Masako Kiyono, Toru Fujiwara, Stephan Clemens
Phytochelatin (PC) synthesis has been well demonstrated as a major metal tolerance mechanism in Arabidopsis thaliana, whereas its contribution to long-distance element transport especially in monocots remains elusive. Using rice as a cereal model, we examined physiological roles of OsPCS1 in the distribution and detoxification of arsenic (As) and cadmium (Cd), two toxic elements associated with major food safety concerns. First, we isolated four different transcript variants of OsPCS1 as well as one from OsPCS2...
August 14, 2017: Plant & Cell Physiology
Peter W Nyhuis, Eva Niederhofer, Norbert Scherbaum, Fabrizio Schifano, Udo Bonnet, Nikolai Dembski, Anna Niederhofer, Michael Specka, Meike Tenbergen
BACKGROUND: The cognitive behavioral therapy has been extensively investigated to assess relapse prevention rates in patients with alcohol dependence. In contrast, only little is known regarding the effectiveness of psychoanalytical psychotherapy in relapse prevention, although this treatment is widely used and especially so in Germany. The aim of this quasi-randomized study was to compare the effectiveness of these two group treatments' approaches under the condition of routine outpatient treatment in a non-university hospital...
October 10, 2017: Substance Use & Misuse
Ruohan Liu, Tiantian Jia, Yuan Cui, Hongjin Lin, Shu Li
Cadmium (Cd) is a highly toxic heavy metal that can affect human and animal health. Selenium (Se) is an essential microelement that can protect various organs against toxic heavy metals. Although many studies have investigated the adverse effect of Cd in rats and several other animals, little is known regarding the mechanisms of Cd-induced autophagy in the chicken pancreas and the antagonistic effect of Se on Cd. In the current study, we fed chickens Se, Cd, or Se and Cd supplements to establish the Se and Cd interaction model and to measure the concentrations of Se and Cd in the chicken pancreas...
October 9, 2017: Biological Trace Element Research
Dieter Lenoir, Karl-Werner Schramm
Detoxification of cigarette smoke employing copper compounds has a potential for the formation of polychlorinated dibenzo-p-dioxins and dibenzofurans and should not be practiced before the degree of formation has been shown to be harmless.
October 10, 2017: Nanoscale
Noriyuki Matsuda, Mayumi Kimura, Bruno Barros Queliconi, Waka Kojima, Masaki Mishima, Kenji Takagi, Fumika Koyano, Koji Yamano, Tsunehiro Mizushima, Yutaka Ito, Keiji Tanaka
DJ-1 (also known as PARK7) has been identified as a causal gene for hereditary recessive Parkinson's disease (PD). Consequently, the full elucidation of DJ-1 function will help decipher the molecular mechanisms underlying PD pathogenesis. However, because various, and sometimes inconsistent, roles for DJ-1 have been reported, the molecular function of DJ-1 remains controversial. Recently, a number of papers have suggested that DJ-1 family proteins are involved in aldehyde detoxification. We found that DJ-1 indeed converts methylglyoxal (pyruvaldehyde)-adducted glutathione (GSH) to intact GSH and lactate...
October 9, 2017: Scientific Reports
Antonio E Muñiz
BACKGROUND: Valproic acid (VPA) is increasingly used to treat a variety of medical disorders, such as seizures, psychiatric disorders, and headaches. Therefore, accidental and intentional ingestions with valproic acid are increasing. OBJECTIVES: A case is presented in an adolescent with ischemic electrocardiographic changes after an acute overdose with VPA. DISCUSSION: Major features of a valproic acid overdose include respiratory depression, progressive coma, hepatotoxicity, thrombocytopenia, and hemodynamic instability...
September 2017: Journal of Emergency Medicine
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