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https://www.readbyqxmd.com/read/28932402/comparative-study-of-sickle-cell-anemia-and-hemoglobin-sc-disease-clinical-characterization-laboratory-biomarkers-and-genetic-profiles
#1
Milena Magalhães Aleluia, Teresa Cristina Cardoso Fonseca, Regiana Quinto Souza, Fábia Idalina Neves, Caroline Conceição da Guarda, Rayra Pereira Santiago, Bruna Laís Almeida Cunha, Camylla Villas Boas Figueiredo, Sânzio Silva Santana, Silvana Sousa da Paz, Júnia Raquel Dutra Ferreira, Bruno Antônio Veloso Cerqueira, Marilda de Souza Gonçalves
BACKGROUND: In this study, we evaluate the association of different clinical profiles, laboratory and genetic biomarkers in patients with sickle cell anemia (SCA) and hemoglobin SC disease (HbSC) in attempt to characterize the sickle cell disease (SCD) genotypes. METHODS: We conducted a cross-sectional study from 2013 to 2014 in 200 SCD individuals (141 with SCA; 59 with HbSC) and analyzed demographic data to characterize the study population. In addition, we determined the association of hematological, biochemical and genetic markers including the β(S)-globin gene haplotypes and the 3...
2017: BMC Hematology
https://www.readbyqxmd.com/read/28894559/pattern-of-cerebral-blood-flow-velocity-using-transcranial-doppler-ultrasonography-in-children-with-sickle-cell-disorder-in-lagos-state-nigeria
#2
Motunrayo Oluwabukola Adekunle, Adeola Barakat Animasahun, Ijeoma Nnenna Diaku-Akinwumi, Olisamedua Fidelis Njokanma
Cerebrovascular accident (CVA) is a common, devastating neurological complication of sickle cell disorder (SCD) with a high recurrent and mortality rate. The Stroke Prevention Trial in Sickle Cell Anaemia study (STOP) recommends routine screening with transcranial Doppler ultrasonography in children aged two to sixteen years with SCD. The present study assessed cerebral blood flow velocities of children with SCD in accordance with the recommendation of routine screening by the STOP study. METHODS: Transcranial Doppler ultrasonography was done for children with SCD that attended Sickle Cell Foundation, Nigeria between July and November 2015...
2017: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/28885599/family-social-environment-and-parenting-predictors-of-alcohol-use-among-adolescents-in-lithuania
#3
Linas Šumskas, Apolinaras Zaborskis
The role of the family as the social environment in shaping adolescent lifestyle has recently received substantial attention. This study was focused on investigating the association between familial and parenting predictors and alcohol use in school-aged children. Adolescents aged 13- and 15-year from a representative sample (N = 3715) of schools in Lithuania were surveyed during the spring of 2014. The methodology of the cross-national Health Behaviour in School-aged Children (HBSC) study was applied. HBSC international questionnaires were completed in the classroom anonymously for obtaining information about drinking of alcoholic beverages and family characteristics-family's affluence and structure, style of communication in the family, parenting style, parental monitoring, family time together, etc...
September 8, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28869880/psychometric-properties-of-the-adverse-childhood-experiences-abuse-short-form-ace-asf-among-romanian-high-school-students
#4
Franziska Meinck, Alina Paula Cosma, Christopher Mikton, Adriana Baban
Child abuse is a major public health problem. In order to establish the prevalence of abuse exposure among children, measures need to be age-appropriate, sensitive, reliable and valid. This study aimed to investigate the psychometric properties of the Adverse Childhood Experiences Questionnaire Abuse Short Form (ACE-ASF). The ACE-ASF is an 8-item, retrospective self-report questionnaire measuring lifetime physical, emotional and sexual abuse. Data from a nationally representative sample of 15-year-old, school-going adolescents (n=1733, 55...
September 1, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28790534/laboratory-and-genetic-biomarkers-associated-with-cerebral-blood-flow-velocity-in-hemoglobin-sc-disease
#5
Rayra Pereira Santiago, Camilo Vieira, Corynne Stephanie Ahouefa Adanho, Sanzio Silva Santana, Caroline Conceição Guarda, Camylla Vilas Boas Figueiredo, Luciana Magalhães Fiuza, Thassila Nogueira Pitanga, Junia Raquel Dutra Ferreira, Milena Magalhães Aleluia, Rodrigo Mota Oliveira, Dalila Luciola Zanette, Isa Menezes Lyra, Marilda Souza Goncalves
Reference values for cerebral blood flow velocity (CBFV) in hemoglobin SC disease (HbSC) have not been established. We aimed to investigate associations between laboratory and genetic biomarkers associated with CBFV in HbSC children. Sixty-eight HbSC children were included; CBFV was analyzed by transcranial Doppler, and the time-averaged maximum mean velocity (TAMMV) was estimated. Hematological, biochemical, immunological, and genetic analyses were performed. TAMMV was negatively correlated with red blood cell count (RBC) count, hemoglobin, hematocrit, and direct bilirubin (DB), yet positively correlated with monocytes and ferritin...
2017: Disease Markers
https://www.readbyqxmd.com/read/28752751/trends-in-medically-attended-injuries-in-czech-adolescents
#6
Kwok Ng, Dagmar Sigmundová, Erik Sigmund, Jan Pavelka, Zdeněk Hamřík, Michal Molcho, Michal Kalman
OBJECTIVE: Due to the importance of surveillance of injuries and accidents in the Czech Republic, the purpose of this study was to report the temporal trends of injuries of Czech adolescents between 2002 and 2014. METHODS: Adolescents (N=20,038) from the Czech Republic, that took part in the 2002, 2006, 2010 and 2014 HBSC study, reported the frequency of medically attended injuries in the past 12 months. Repeated binary logistic regressions with different years as reference categories were performed...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752750/trends-in-children-s-toothbrushing-in-the-czech-republic-from-1994-to-2014-results-of-the-hbsc-study
#7
Jana Vašíčková, Tomáš Hollein, Dagmar Sigmundová, Sisko Honkala, Jan Pavelka, Michal Kalman
OBJECTIVE: Brushing one's teeth twice a day is the main self-care method to prevent the most prevalent non-communicable diseases. The aim of the study is to describe the trends in brushing teeth in 11-, 13-, and 15-year-old Czech children between 1994 and 2014. METHODS: One question about oral health from the HBSC study protocol was used in the six surveys (1994, 1998, 2002, 2006, 2010, and 2014). Altogether, 21,170 answers from boys and girls were analyzed using statistical description and binominal logistic regression...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752749/trends-in-life-satisfaction-and-self-rated-health-in-czech-school-aged-children-hbsc-study
#8
Lenka Hodačová, Eva Hlaváčková, Dagmar Sigmundová, Michal Kalman, Jaroslava Kopčáková
OBJECTIVE: The aim of the study is to examine cross-sectional time trends of life satisfaction and self-rated health in a representative sample of Czech children aged 11, 13 and 15 years using the Health Behaviour in School-aged Children (HBSC) study data from the Czech Republic. METHODS: Data from survey years 2002, 2006, 2010 and 2014 was used. The sample consisted of 16,357 participants (48.5% of boys). Life satisfaction (LS) was measured by Cantril's ladder; self-rated health was measured through the simple item "Would you say your health is: excellent, good, fair, poor"...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752746/trends-in-parent-adolescent-communication-in-the-czech-republic-between-2002-and-2014-results-of-the-hbsc-study
#9
Jana Vokáčová, Jana Vašíčková, Lenka Hodačová, Zuzana Půžová, Izabela Tabak
OBJECTIVE: Good parent-child communication is associated with adolescent well-being. The aim of the present study was to report time trends in parent-adolescent communication in biological and stepfamilies in the Czech Republic between 2002 and 2014 and to assess gender and age differences. METHODS: The research sample consisted of 16,160 adolescents aged 11, 13, and 15 years (48.1% of boys) who participated in the 2002, 2006, 2010 and 2014 surveys within the Health Behaviour in School-aged Children (HBSC) study in the Czech Republic...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752745/national-time-trends-in-bullying-among-adolescents-in-the-czech-republic-from-1994-to-2014
#10
Mária Sarková, Dagmar Sigmundová, Michal Kalman
OBJECTIVE: Bullying in school is a public health concern which continues to be a serious threat to physical and emotional health of children and adolescents. The purpose of this study is to examine trends in bullying behaviour among school-aged children in the Czech Republic. METHODS: Data were obtained from cross-sectional self-report surveys in the years 1994-2014 as a part of the Health Behaviour in School-aged Children study (HBSC) from a representative sample of 11-, 13-, and 15-year olds...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752744/trends-in-perception-of-psychosocial-school-environment-hbsc-study-2002-2014-in-the-czech-republic
#11
Jana Vašíčková, Tomáš Hollein, Erik Sigmund, Ferdinand Salonna, Zuzana Boberová
OBJECTIVE: School is a place where students spend most of their daytime hours. Previous studies indicate that the class climate significantly affects students in both positive and negative ways. The aim of our study is to describe the trends in the psychosocial school environment based on four surveyed years in the Czech Republic. METHODS: The trends in perception of school were assessed by the standardised self-reported HBSC questionnaire from data collected in 2002, 2006, 2010, and 2014...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752743/trends-in-active-commuting-to-school-among-czech-schoolchildren-from-2006-to-2014
#12
Jan Pavelka, Dagmar Sigmundová, Zdeněk Hamřík, Michal Kalman, Erik Sigmund, Frida Mathisen
OBJECTIVE: Active commuting (AC) is an important factor in increasing the total daily physical activity (PA) in children, which is significant for their health and positive physical behaviour in adulthood. The objective of the study was to describe trends in active commuting to school among Czech girls and boys aged 11-15 years from 2006 to 2014, using data from the Health Behaviour in School-aged Children (HBSC) study. METHODS: To investigate trends in AC among Czech children of school age data obtained from the HBSC surveys carried out in 2006, 2010, and 2014 was used...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752742/trends-in-screen-time-behaviours-in-czech-schoolchildren-between-2002-and-2014-hbsc-study
#13
Dagmar Sigmundová, Erik Sigmund, Jens Bucksch, Petr Baďura, Michal Kalman, Zdeněk Hamřík
OBJECTIVE: Screen-based behaviours such as watching television or computer use are among the most prevalent sedentary behaviours adolescents spend time on. There is a lack of recent estimates on prevalence and changes in the amount of time spent on screen-based behaviour across Central and Eastern Europe. The main aim is to assess the trends in the prevalence of current recommendations for the screen time (≤2 hours per day) of school-aged children in the Czech Republic between 2002 and 2014...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752741/trends-in-overweight-and-obesity-in-czech-schoolchildren-from-1998-to-2014
#14
Zdeněk Hamřík, Dagmar Sigmundová, Jan Pavelka, Michal Kalman, Erik Sigmund
OBJECTIVE: Overweight and obesity in adolescents is associated with many health risks and considerable direct and indirect healthcare costs. The purpose of this study is to examine trends in the prevalence of overweight and obesity in 11-, 13- and 15-year-old adolescents in the Czech Republic from 1998 to 2014. METHODS: Data from five self-reported survey rounds (1998, 2002, 2006, 2010, and 2014) of the Health Behaviour in School-aged Children Study (HBSC) were used to assess trends in overweight and obesity among Czech adolescents...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752740/methodological-aspects-of-trend-studies-and-development-of-the-hbsc-study-in-the-czech-republic
#15
Erik Sigmund, Petr Baďura, Dagmar Sigmundová, Ladislav Csémy, Michal Kalman
The aim of the study is to present the theoretical background of trend studies in general, to characterize the international Health Behaviour in School-aged Children (HBSC) study and to describe its methodology and changes of the Czech HBSC study between 1994 and 2014. The first part describes various types of trend research studies including their advantages and disadvantages. The second part summarizes the history of the HBSC study in an international context and particularly in the Czech Republic. The final part presents the basic methodological data from six surveys conducted in the Czech Republic between 1994 and 2014...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28752739/trends-in-health-behaviour-in-czech-school-aged-children-hbsc-study-preface
#16
Michal Kalman
The Health Behaviour in School-aged Children (HBSC) study is now in its 34th year. It continues to grow not only as a source of reliable and valid data on the health behaviours of 11-, 13- and 15-year-olds, but also regarding its membership - 46 countries and regions across Europe and North America are now included. The HBSC study is a cohort cross-sectional questionnaire-based study focusing on health and health-related behaviours in adolescents in the context of their social environment. This age was selected because of the significant cognitive, psychological, and biological processes taking place in this period of the lifespan, as well as because of the fact that health-related behaviours adopted at this age are known to persist into adulthood...
July 2017: Central European Journal of Public Health
https://www.readbyqxmd.com/read/28749037/transfusion-for-sickle-cell-disease-in-pregnancy-a-single-centre-survey
#17
J Sharif, L Byrd, K Stevenson, J Raddats, E Morsman, K Ryan
INTRODUCTION: Sickle cell disease in pregnancy carries a high risk of maternal and fetal adverse outcomes. The use of prophylactic transfusions to reduce the risk of sickle complications is controversial. Current UK standards do not recommend the routine use of transfusion for sickle pregnancy. We examined transfusion episodes during sickle pregnancies in a single centre over an 11-year period. METHODS: We conducted a retrospective observational study of all pregnancies in patients with sickle cell disease who attended the joint obstetric/haematology clinic over an 11-year period...
July 27, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28711812/bullying-involvement-and-adolescent-substance-use-a-multilevel-investigation-of-individual-and-neighbourhood-risk-factors
#18
Laura J Lambe, Wendy M Craig
BACKGROUND: Youth involved with school bullying are vulnerable to many negative outcomes, including substance use. Research has yet to examine how this vulnerability operates in the context of other individual and neighbourhood differences. The current study aimed to fill this gap by using multilevel modeling to investigate both the individual and neighbourhood risk factors associated with frequent drunkenness and frequent cannabis use among adolescents. METHODS: Data from the 2010 Canadian Health Behaviours in School-Aged Children (HBSC) survey were analyzed...
June 29, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28683515/profile-of-reproductive-issues-associated-with-different-sickle-cell-disease-genotypes
#19
Flávia Anchielle Carvalho, Ariani Impieri Souza, Ana Laura Carneiro Gomes Ferreira, Simone da Silva Neto, Ana Carolina Pessoa de Lima Oliveira, Maria Luiza Rodrigues Pinheiro Gomes, Manuela Freire Hazin Costa
Purpose To describe the reproductive variables associated with different sickle cell disease (SCD) genotypes and the influence of contraceptive methods on acute painful episodes among the women with the homozygous hemoglobin S (HbSS) genotype. Methods A cross-sectional study was conducted between September of 2015 and April of 2016 on 158 women afflicted with SCD admitted to a hematology center in the Northeast of Brazil. The reproduction-associated variables of different SCD genotypes were assessed using the analysis of variance (ANOVA) test to compare means, and the Kruskal-Wallis test to compare medians...
August 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28673131/health-literacy-and-participation-in-sports-club-activities-among-adolescents
#20
Leena Paakkari, Sami Kokko, Jari Villberg, Olli Paakkari, Jorma Tynjälä
AIMS: The aim of this research was to compare the levels of perceived health literacy among adolescents who do or do not participate in sports club activities. Organized sport club activities reach a high proportion of adolescents, and have the potential to contribute to the development of their health literacy. METHODS: The cross-sectional data on health literacy among school children in Finland (aged 13 and 15, n=3852) were measured, as a part of the Health Behaviour in School-Aged Children (HBSC) study, using the Health Literacy for School-aged Children (HLSAC) instrument...
July 1, 2017: Scandinavian Journal of Public Health
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