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https://www.readbyqxmd.com/read/29223434/durability-of-quality-of-life-benefits-of-transcatheter-aortic-valve-replacement-long-term-results-from-the-corevalve-us-extreme-risk-trial
#1
Suzanne J Baron, Suzanne V Arnold, Matthew R Reynolds, Kaijun Wang, Michael Deeb, Michael J Reardon, James Hermiller, Steven J Yakubov, David H Adams, Jeffrey J Popma, David J Cohen
BACKGROUND: For patients with severe aortic stenosis (AS) at extreme surgical risk, transcatheter aortic valve replacement (TAVR) leads to improved survival and health status when compared with medical therapy. Whether the early health status benefits of TAVR in these patients are sustained beyond 1 year of follow-up is unknown. METHODS AND RESULTS: Six hundred thirty-nine patients with severe AS at extreme surgical risk underwent TAVR in the CoreValve US Extreme Risk Pivotal trial...
December 2017: American Heart Journal
https://www.readbyqxmd.com/read/29222864/effects-of-cardiac-resynchronization-therapy-after-inferior-myocardial-infarction-on-secondary-mitral-regurgitation-and-mitral-valve-geometry
#2
Christos G Mihos, Evin Yucel, Romain Capoulade, Mary P Orencole, Gaurav A Upadhyay, Orlando Santana, Jagmeet P Singh, Michael H Picard
BACKGROUND: The effects of cardiac resynchronization therapy (CRT) on secondary mitral regurgitation (MR), and mitral valve (MV) and left ventricular (LV) geometry, in patients with prior inferior myocardial infarction is not clearly defined. We assessed these outcomes utilizing 2-dimensional echocardiography, and analyzed echocardiographic geometric variables that may correlate with follow-up MR severity. METHODS: Between 2009 and 2012, 229 CRT were implanted. Twenty-two had prior inferior myocardial infarction, ≥ mild MR at baseline, and serial echocardiography...
December 9, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29217649/an-unusual-cause-of-hypoxia-getting-to-the-heart-of-the-matter
#3
Daniel Hammersley, Aamire Shamsi, Mohammad Murtaza Zaman, Phillip Berry, Lydia Sturridge
A 63 year old female presented to hospital with progressive exertional dyspnoea over a 6 month period. In the year preceding her admission, she reported an intercurrent history of abdominal pain, diarrhoea and weight loss. She was found to be hypoxic, the cause for which was initially unclear. A ventilation-perfusion scan identified a right-to-left shunt. Transoesophageal echocardiography (TOE) demonstrated a significant right-to-left intracardiac shunt through a patent foramen ovale (PFO); additionally severe tricuspid regurgitation was noted through a highly abnormal tricuspid valve...
December 7, 2017: Echo Research and Practice
https://www.readbyqxmd.com/read/29216666/-cardiac-rehabilitation
#4
Bernhard Schwaab
Physical training, psychosocial intervention, nutrition counselling and optimisation of secondary preventive medication to reduce morbidity and mortality of the disease as well as the reintegration into social life and return to work are equivalent goals of cardiac rehabilitation. This requires multifactorial intervention by a multidisciplinary team. In Germany, cardiac rehabilitation starting early after an index event could demonstrate a significant reduction of total mortality, myocardial infarction and hospitalisation during a follow-up of 1-2 years in 5 controlled cohort studies including 12 556 patients after myocardial infarction and CABG surgery...
December 7, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/29214833/living-with-functionally-univentricular-heart-beating-the-odds
#5
Safak Alpat, Metin Demircin
An unoperated 45-year-old man with double-inlet single left ventricle, transposed great arteries, ventricular septal defect, and pulmonary stenosis presented with mitral and pulmonary valvular vegetations unresponsive to antibiotic therapy. The initial diagnosis was made with echocardiography, and the morphology was delineated with computed tomography and magnetic resonance imaging. The patient underwent mitral valve replacement with a mechanical valve and pulmonary valve vegetectomy. He recovered well and he is currently well two years after the operation...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29209780/quality-of-work-experience-after-angioplasty-or-heart-surgery-a-monocentric-cohort-study
#6
Massimo Miglioretti, Andrea Gragnano, Giacomo Baiardo, Gaia Savioli, Luca Corsiglia, Raffaele Griffo
PURPOSE: The study evaluated work experience changes and its determinants after return to work (RTW) in angioplasty or heart surgery patients. METHODS: During a 1-year period (2014) in a Rehabilitation Hospital in northwestern Italy, we approached 253 patients (19.3% of inpatients). 199 patients consented to complete a survey on job characteristics, job satisfaction, job involvement, illness perception, depression, anxiety, adherence to therapy, and sociodemographic characteristics...
December 5, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/29207363/improvement-in-aortic-valve-area-in-patients-with-aortic-stenosis-through-use-of-a-new-hourglass-shaped-valvuloplasty-balloon
#7
Elizabeth Goldenberg, Wesley Pedersen, Emmanouil S Brilakis, Michael Mooney, Mario Gössl, Anil Poulose, Bilal Murad, James Kolbeck, Paul Sorajja
OBJECTIVES: The study aim was to assess the effect of hourglass-shaped V8 and TAV8 balloons (InterValve, Inc) on aortic valve area (AVA) and other outcomes in patients with severe aortic stenosis undergoing balloon aortic valvuloplasty (BAV). BAV has re-emerged with transcatheter therapy. Cylindrical balloons have been the device of choice despite limitations. The hourglass-shaped balloons, with shorter, broader segments separated by a narrowed waist, permit enhanced fixation and better leaflet opening without annular or sinotubular compromise...
December 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29206746/mitral-valve-and-subvalvular-repair-for-secondary-mitral-regurgitation-rationale-and-clinical-outcomes-of-the-papillary-muscle-sling
#8
Christos G Mihos, Romain Capoulade, Evin Yucel, Steve Xydas, Francesco Nappi, Roy F Williams, Orlando Santana
Secondary mitral regurgitation (MR) is a common finding in patients with dilated cardiomyopathy, and it is associated with poor outcomes. It is the result of incomplete systolic closure of the mitral valve (MV) as a consequence of left ventricular dilatation, papillary muscle displacement with impaired systolic shortening, and mitral leaflet tethering. MV surgery may be performed in cases of significant secondary MR despite guideline-directed medical therapy. However, MV repair, which is most commonly performed with an undersized ring annuloplasty, is associated with a 30-60% recurrence of moderate or greater MR at mid-term follow-up...
January 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29204737/initial-slovenian-experience-with-mitraclip-therapy-careful-selection-of-patients-is-crucial-for-optimal-outcome
#9
Jana Ambrožič, Marta Cvijič, Mojca Bervar, Špela Mušič, Matjaž Bunc
BACKGROUND: MitraClip is a percutaneous mitral repair technology increasingly used for high surgical risk patients with primary or secondary mitral regurgitation. We describe initial Slovenian experience with MitraClip and discuss the importance of identifying the suitable candidates for this procedure. METHODS: We retrospectively analyzed the first 10 patients (mean age 75.6 ± 6.9 years, logistic Euroscore 28.4 ± 10.9%) with severe and moderate to severe mitral regurgitation (8 secondary, 1 primary and 1 mixed etiology) who underwent a MitraClip procedure between January 2015 and February 2017...
December 4, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/29201439/management-of-an-acute-ischemic-stroke-during-thrombolytic-treatment-in-a-pregnant-patient-with-prosthetic-valve-thrombosis
#10
Macit Kalçık, Mahmut Yesin, Emrah Bayam, Mustafa Ozan Gürsoy, Ahmet Güner, Sabahattin Gündüz, Mehmet Özkan
Prosthetic valve thrombosis (PVT) is a life-threatening complication in pregnant women with mechanical prosthetic heart valves. Thrombolytic therapy (TT) has evolved as an effective treatment alternative to surgery, which is associated with very high maternal and fetal mortality and morbidity in these patients. Acute ischemic stroke may rarely occur during TT for PVT. Here, we present a pregnant patient who was complicated with cerebral thromboembolism during TT for PVT and successfully managed with continuation of TT...
September 2017: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/29196230/functional-anatomy-and-pathophysiologic-principles-in-mitral-regurgitation-non-invasive-assessment
#11
REVIEW
Sylvestre Maréchaux, Jeffery E Illman, James Huynh, Hector I Michelena, Vuyisile T Nkomo, Christophe Tribouilloy
Mitral regurgitation (MR) is the most prevalent cause of valvular heart disease (VHD) in western countries. In the Euro Heart Survey on VHD, MR was the second most common heart VHD requiring surgery. It is also the most common form of VHD in community and population-based studies from the United States. The categorization of MR based on causes and mechanisms is a major determinant of clinical outcome, of possible therapies for the MR and of the effectiveness of these therapies. Surgical mitral valve (MV) repair has been shown to improve survival in patients with severe primary MR compared with MV replacement...
November 28, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29194051/blood-tissue-and-imaging-biomarkers-in-calcific-aortic-valve-stenosis-past-present-and-future
#12
Mylène Shen, Lionel Tastet, Jutta Bergler-Klein, Philippe Pibarot, Marie-Annick Clavel
PURPOSE OF REVIEW: Calcific aortic valve stenosis is the most prevalent valvular heart disease in the high-income countries. To this date, no medical therapy has been proven to prevent or to stop the progression of aortic valve stenosis. The physiopathology of aortic valve stenosis is highly complex and involves several signalling pathways, as well as genetic related factors, which delay the elaboration of effective pharmacotherapies. Moreover, it is difficult to predict accurately the progression of the valve stenosis and finding the optimal timing for aortic valve replacement remains challenging...
November 30, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29189832/-peripheral-embolization-and-rapid-growth-of-papillary-fibroelastoma-in-a-young-woman
#13
Alessandro Minati, Danilo Ruggiero, Florida Gripshi, Antonella Cherubini, Lorenzo Zandonà, Andrea Di Lenarda, Aniello Pappalardo
Papillary fibroelastoma, a benign cardiac tumor, is a rare clinical condition. Before the echocardiography era, the diagnosis was often occasional, especially during other cardiac procedures; but nowadays it has improved with the advent of higher-resolution imaging technology. The clinical presentation can vary from asymptomatic to severe complications such as cerebrovascular or ischemic events due to tumor embolization.We present the case of a 33-year-old female with a papillary fibroelastoma on the anterior leaflet of the mitral valve undergoing clinical examination for claudicatio intermittens...
December 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29188357/-management-of-valvular-heart-disease-esc-eacts-guidelines-2017
#14
REVIEW
M Haude
After 5 years the European Society of Cardiology and the European Association for Cardio-Thoracic Surgery have released an update on the guidelines for the management of valvular heart diseases. In recent years published results of randomized trials in patients with aortic valve stenosis have resulted in updated recommendations for catheter-based prosthesis implantation (TAVI), which is now extended to patients presenting without a low risk for conventional surgical valve replacement. In mitral or tricuspid valvular disease, the recommendations for catheter-based therapies are less strong because of a lack of supportive scientific data...
December 2017: Herz
https://www.readbyqxmd.com/read/29184602/-giant-lithiasis-due-to-urinary-stasis-related-to-ileo-caecal-bladder
#15
Hamza Dergamoun, Zayd El Boukili El Makhoukhi
Bladder exstrophy is a malformation characterized by subumbilical anterior abdominal wall and anterior bladder wall deishence. It affects nearly 30.000-40.000 births per year, with a higher prevalence in boys. External continent urinary diversion creates a long-term outcome. However, it is not devoid of complications. We report the case of a 30-year old female patient who had undergone cystectomy with bladder replaced with ileo-caecal segment for bladder exstrophy 13 years earlier. She was followed up for 5 years and then lost to follow up...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29184415/reversible-preoperative-renal-dysfunction-does-not-add-to-the-risk-of-postoperative-acute-kidney-injury-after-cardiac-valve-surgery
#16
Jia-Rui Xu, Ya-Min Zhuang, Lan Liu, Bo Shen, Yi-Mei Wang, Zhe Luo, Jie Teng, Chun-Sheng Wang, Xiao-Qiang Ding
Objective: To evaluate the impact of the renal dysfunction (RD) type and change of postoperative cardiac function on the risk of developing acute kidney injury (AKI) in patients who underwent cardiac valve surgery. Method: Reversible renal dysfunction (RRD) was defined as preoperative RD in patients who had not been initially diagnosed with chronic kidney disease (CKD). Cardiac function improvement (CFI) was defined as postoperative left ventricular ejection function - preoperative left ventricular ejection function (ΔEF) >0%, and cardiac function not improved (CFNI) as ΔEF ≤0%...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29181740/impact-of-mitral-valve-intervention-with-left-ventricular-assist-device-implantation-on-postoperative-outcomes-and-morphologic-change
#17
Hiroki Hata, Tomoyuki Fujita, Hatsue Ishibashi-Ueda, Kensuke Kuroda, Osamu Seguchi, Yorihiko Matsumoto, Masanobu Yanase, Takuma Sato, Seiko Nakajima, Norihide Fukushima, Junjiro Kobayashi
Although mitral regurgitation (MR) is prevalent in patients with end-stage heart failure, the impact of mitral valve (MV) surgery on outcomes after left ventricular assist device (LVAD) implantation and morphologic changes of MV remains unclear. We retrospectively reviewed 74 patients who underwent LVAD implantation as a bridge to transplant. Of these, 11 (15%) underwent MV repair concomitant with or prior to LVAD implantation, while 27 patients with preoperative significant (moderate or greater) MR did not undergo concomitant MV surgery...
November 27, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29181418/asymptomatic-cardiovascular-syphilis-with-aortic-regurgitation-requiring-surgical-repair-in-an-hiv-infected-patient
#18
Daniel S Graciaa, Marina B Mosunjac, Kimberly A Workowski, Russell R Kempker
A 47-year-old man with HIV infection presented 10 years after initial secondary syphilis diagnosis and treatment for routine follow-up. His HIV was well controlled on antiretroviral therapy. Rapid plasma reagin was 1:1, and TP-PA was reactive. Physical examination revealed a wide pulse pressure, a systolic murmur, and an early diastolic decrescendo murmur. Echocardiogram revealed moderate to severe aortic regurgitation, and subsequent computed tomography angiogram showed a 6.8-cm fusiform aneurysm of the proximal ascending aorta...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29181299/persistent-bacteremia-secondary-to-delayed-identification-of-lactobacillus-in-the-setting-of-mitral-valve-endocarditis
#19
Cody Stroupe, Joseph Pendley, Emmanuel Isang, Benjamin Helms
Introduction: Lactobacillus species causing infective endocarditis is rare. Most reported cases arise from the oral ingestion of Lactobacillus via dairy or nutritional supplements in patients with congenital valve disease or replacement. We present a case of native valve bacterial endocarditis caused by Lactobacillus arising from dental abscesses. Additionally, there was an error in identification of the Lactobacillus as Corynebacterium, which led to inadequate treatment. Presentation of case: A 51-year-old male presented to an outside clinic with several weeks of subjective fevers and malaise...
2017: IDCases
https://www.readbyqxmd.com/read/29181043/results-of-open-heart-surgery-in-jehovah-s-witness-patients-single-centre-experience
#20
Andrzej Juraszek, Piotr Kołsut, Jarosław Szymański, Jarosław Kuriata, Krzysztof Kuśmierski, Ewa Sitkowska-Rysiak, Małgorzata Jasińska, Mariusz Kuśmierczyk
Aim: Evaluation the results in patients from the religious community of Jehovah's Witness (JW) undergoing open heart surgery at our institution. Material and methods: Between September 2011 and March 2015, 21 patients with a religious background of the JW church underwent open heart surgery at our institution performed by the same surgical team. Mean age was 68.43 ±8.93 years. There were 13 (61.9%) female patients. Recombinant human erythropoietin was administered to every patient with a hemoglobin value < 12...
September 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
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