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knee ligaments pathology

John A Heflin, Scott Ford, Peter Stevens
Blount's disease is commonly attributed to an intrinsic, idiopathic defect in the posteromedial proximal tibial physis resulting in progressive bowing of the leg, intoeing, and lateral knee thrust. Treatment has historically included bracing, physeal stapling, or corrective osteotomy, and was determined primarily by age at presentation. As we feel the pathology is not necessarily age dependent, we have elected to use the technique of guided growth using a lateral tension band plate to correct limb alignment as a first-line treatment in all patients presenting to our clinic as long as they had growth remaining and no evidence of a physeal bar...
October 2016: Medicine (Baltimore)
Timothy I Alves, Gandikota Girish, Monica Kalume Brigido, Jon A Jacobson
Pain and other disorders of the knee are a common presenting complaint in the ambulatory setting. Although the cornerstones of imaging evaluation of the knee are radiographs and magnetic resonance (MR) imaging, ultrasonography (US) is less expensive than MR imaging, easily available, and of comparable accuracy in the evaluation of certain pathologic conditions of the knee. The benefits of US include portability, low cost, high spatial resolution, dynamic imaging, and ability to guide percutaneous interventions when indicated...
October 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
M Cody O'Dell, Diego Jaramillo, Laura Bancroft, Laura Varich, Gregory Logsdon, Sabah Servaes
With increasing participation and intensity of training in youth sports in the United States, the incidence of sports-related injuries is increasing, and the types of injuries are shifting. In this article, the authors review sports injuries of the lower extremity, including both acute and overuse injuries, that are common in or specific to the pediatric population. Common traumatic injuries that occur in individuals of all ages (eg, tears of the acetabular labrum and anterior cruciate ligament) are not addressed, although these occur routinely in pediatric sports...
October 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
Richard Kijowski, Humberto Rosas, Alexey Samsonov, Kevin King, Rob Peters, Fang Liu
PURPOSE: To investigate the feasibility of using compressed sensing (CS) to accelerate three-dimensional fast spin-echo (3D-FSE) imaging of the knee. MATERIALS AND METHODS: A 3D-FSE sequence was performed at 3T with CS (CUBE-CS with 3:16-minute scan time) and without CS (CUBE with 4:44-minute scan time) twice on the knees of 10 healthy volunteers to assess signal-to-noise ratio (SNR) using the addition-subtraction method and once on the knees of 50 symptomatic patients to assess diagnostic performance...
October 11, 2016: Journal of Magnetic Resonance Imaging: JMRI
Michael D Ringler, Ezekiel E Shotts, Mark S Collins, B Matthew Howe
OBJECTIVE: Unlike with anterior cruciate ligament injury, little is known about the prevalence of intra-articular pathology associated with isolated posterior cruciate ligament (PCL) injury in the knee. The objectives of this study were to characterize and identify the frequency of meniscal tears and osteochondral injuries in these patients, and to see if management might be affected. MATERIALS AND METHODS: Altogether, 48 knee MRI exams with isolated PCL tears were evaluated for the presence of: grade and location of PCL tear, meniscal tear, articular chondral lesion, bone bruise, and fracture...
October 4, 2016: Skeletal Radiology
Olga Katsara, Mukundan Attur, Rachel Ruoff, Steven B Abramson, Victoria Kolupaeva
Objectives Degeneration of articular cartilage is central to OA pathology; however, the molecular mechanisms leading to these irreversible changes are still poorly understood. Here, we investigated how changes in the chondrocyte translational apparatus may contribute to the pathology of OA. Methods Normal and OA human knee cartilage was used to analyze the activity of different components of the translational machinery. Chondrocytes isolated from lesional and non-lesional areas of OA cartilage were used to estimate relative rate of protein synthesis by metabolic labeling...
October 1, 2016: Arthritis & Rheumatology
Christopher V Nagelli, James L Cook, Kei Kuroki, Chantelle Bozynski, Richard Ma, Timothy E Hewett
Complications following anterior cruciate ligament (ACL) injury and reconstruction that include chronic dysfunction, second ACL injury, and posttraumatic osteoarthritis (OA) may be interrelated and stem from the inability to fully restore native ACL integrity and function. The loss of ACL sensory input following injury may significantly contribute to joint dysfunction. We developed a novel preclinical animal model to assess the contributions of ACL sensory afferents to knee joint function and health. We hypothesized that ACL sensory denervation would manifest in knee joint dysfunction and development of early OA...
September 20, 2016: Journal of Knee Surgery
L Felli, G Garlaschi, A Muda, A Tagliafico, M Formica, A Zanirato, M Alessio-Mazzola
PURPOSE: The aim of this study was to compare the accuracy of clinical examination to that of MRI evaluated by two independent radiologists for the diagnosis of meniscal tears and chronic anterior cruciate ligament injuries and to assess the MRI accuracy in the diagnosis of cartilage defects. METHODS: Seventy-six consecutive patients with suspected intra-articular knee pathology were prospectively evaluated by objective examination, 1.5 T MRI, re-examined by trained radiologist and arthroscopy...
September 14, 2016: Musculoskeletal Surgery
Ali Babaei Jandaghi, Mohsen Mardani-Kivi, Ahmadreza Mirbolook, Mohammad Kazem Emami-Meybodi, Solmaz Mohammadzadeh, Maral Farahmand
BACKGROUND: Knee pain is a common problem in the general population. In order to determine the extent of the injury and the appropriate treatment, MRI provides the most accurate imaging method. This may be done through conventional MRI techniques or by injecting a contrast material (MR arthrography). OBJECTIVES: The purpose of this study was to compare the diagnostic value of these two methods. PATIENTS AND METHODS: The study involved the diagnostic evaluation on 60 patients with knee pain who received treatment over the course of a one-year period...
May 2016: Trauma Monthly
Mehmet Fatih Erol, Ozgur Karakoyun
BACKGROUND: A focal full thickness cartilage lesion of knee joint is one of the commonly seen intraarticular pathologies among the joint cartilage problems. Osteochondral autograft transfer mosaicplasty is a method which has satisfactory outcomes among the treatment preferences of cartilage defects. In spite of the favorable clinical results there are some pitfalls of mosaicplasty treatment especially in cases of large defects. One of the major problems of the classical OAT mosaicplasty is the gap spaces between the plugs...
2016: SpringerPlus
Yu Zhang, Wenhan Huang, Zilong Yao, Limin Ma, Zefeng Lin, Shaobai Wang, Huayang Huang
BACKGROUND: Numerous studies have investigated kinematic alterations in patients with an isolated anterior cruciate ligament (ACL) injury. However, a substantial proportion of patients with injured ACLs also have concomitant meniscal tears. PURPOSE: To evaluate the in vivo alteration of knee kinematics after an ACL tear, with or without a combined medial or lateral meniscal tear, during level walking activity. STUDY DESIGN: Controlled laboratory study...
August 10, 2016: American Journal of Sports Medicine
M Faruch-Bilfeld, F Lapegue, H Chiavassa, N Sans
Magnetic resonance imaging has now an indisputable role for the diagnosis of meniscus and ligament injuries of the knee. Some technical advances have improved the diagnostic capabilities of magnetic resonance imaging so that diagnoses, which may change the therapeutic approach, such as a partial tear of the anterior cruciate ligament or confirmation of unstable meniscal injuries, are now made easier. This article describes the essential about magnetic resonance imaging technique and pathological results for the menisci, collateral ligaments and damage to the central pivot of the cruciate knee ligaments...
July 2016: Diagnostic and Interventional Imaging
Weilin Liu, Jian He, Ruhui Lin, Jie Liang, Qinglu Luo
The present study investigated the differential proteomics of synovial membranes between bilateral and unilateral anterior cruciate ligament transection (ACLT) in rabbits with knee osteoarthritis (KOA), in order to elucidate the pathological biomarkers of different degrees of KOA. A total of 6 New Zealand rabbits were randomly divided into groups A and B (three rabbits per group). The two groups were subjected to bilateral and unilateral ACLT, respectively. A total of 6 weeks following surgery, proteins were extracted from the knee joint synovial membranes of KOA rabbits and were separated by two‑dimensional polyacrylamide gel electrophoresis...
September 2016: Molecular Medicine Reports
Sina Pezeshki, Thomas J Vogl, Mohammad Zakaria Pezeshki, Mohammad Hossein Daghighi, Masoud Pourisa
BACKGROUND: magnetic resonance imaging (MRI) as a noninvasive diagnostic tool may help clinicians in the evaluation of injuries to menisci and ligaments. PURPOSE: this study assessed the associations between type of trauma to knee joint, bone bruise, fracture and pathological joint effusion with injuries to menisci and ligaments of knee joint. METHODS: we reviewed knee joint MRI of 175 patients aged less than 45 years old who were referred to MRI center of our University...
January 2016: Muscles, Ligaments and Tendons Journal
Xiao-fang Xi, Xue-zhi Li, Fei Liu, Ni-ni Fu, Yi Ren, Xiao-guang Yang, Yu Zhang
OBJECTIVE: To observe the effectiveness of short thrust needling (STN, close-to-bone needing) plus electroacupuncture (EA) in healing knee cartilage tissue and in regulating expressions of cartilage vitamin K dependent gamma-glutamyl carboxylase (GGCX), matrix metalloproteinase-13 (MMP 13) and serum uncarboxylated matrix gla protein (ucMGP) in rabbits with knee osteoarthritis (KOA), so as to reveal its mechanism underlying improvement of KOA. METHODS: Forty New Zealand rabbits were randomly divided into normal, model, EA and STN+ EA groups (n = 10 in each group)...
April 2016: Zhen Ci Yan Jiu, Acupuncture Research
Yonghui Dong, Hui Liu, Xuejun Zhang, Fei Xu, Liang Qin, Peng Cheng, Hui Huang, Fengjing Guo, Qing Yang, Anmin Chen
Previous studies showed that SDF-1α is a catabolic factor that can infiltrate cartilage, decrease proteoglycan content, and increase MMP-13 activity. Inhibiting the SDF-1α/CXCR4 signalling pathway can attenuate the pathogenesis of osteoarthritis (OA). Recent studies have also shown that SDF-1α enhances chondrocyte proliferation and maturation. These results appear to be contradictory. In the current study, we used a destabilisation OA animal model to investigate the effects of SDF-1α/CXCR4 signalling in the tibial subchondral bone and the OA pathological process...
2016: International Journal of Molecular Sciences
Michael D Harris, Adam J Cyr, Azhar A Ali, Clare K Fitzpatrick, Paul J Rullkoetter, Lorin P Maletsky, Kevin B Shelburne
Modeling complex knee biomechanics is a continual challenge, which has resulted in many models of varying levels of quality, complexity, and validation. Beyond modeling healthy knees, accurately mimicking pathologic knee mechanics, such as after cruciate rupture or meniscectomy, is difficult. Experimental tests of knee laxity can provide important information about ligament engagement and overall contributions to knee stability for development of subject-specific models to accurately simulate knee motion and loading...
August 1, 2016: Journal of Biomechanical Engineering
Abhishek Vaish, Parag Sancheti, Raju Vaishya
INTRODUCTION: The cyst of anterior cruciate ligament (ACL) is a known clinical entity, but its association with knee synovitis and melon or rice bodies is not documented. CASE REPORT: We report a rare case of ganglionic cyst of of the knee in association with diffuse synovitis and multiple melon or rice bodies in a 36 year old male. The case was treated arthroscopically with removal ofthe cyst of ACL and multiple melon seed bodies. CONCLUSION: Information regarding incidence, treatment, and outcomes for patients with synovial cysts and melon seed bodies is lacking...
January 2016: Journal of Orthopaedic Case Reports
Melissa A Kluczynski, Jeansol V Kang, John M Marzo, Leslie J Bisson
BACKGROUND: The prevalence of comorbid knee pathology has been examined for sports-related anterior cruciate ligament (ACL) injuries, but it has not been examined in ice hockey players. PURPOSE: To compare concomitant bone bruising, collateral ligament injuries, and intra-articular injuries in ACL injuries suffered during ice hockey versus other sports. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: A total of 20 patients with ACL injuries sustained during ice hockey were identified from a prospective registry, of which 95% were male and 90% had a contact mechanism of injury (MOI)...
May 2016: Orthopaedic Journal of Sports Medicine
Daniel J Liechti, Jorge Chahla, Chase S Dean, Justin J Mitchell, Erik Slette, Travis J Menge, Robert F LaPrade
PURPOSE: The purpose of this study was to systematically review the literature on rerevision anterior cruciate ligament (ACL) reconstruction, focusing on patient outcomes. The secondary aims of this study were to (1) identify risk factors that contribute to multiple ACL reconstruction failures (defined as a complete tear of a revision ACL graft with knee instability) and (2) assess concomitant knee injuries, such as articular cartilage and menisci lesions. METHODS: A systematic review of the literature was performed...
June 8, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
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