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knee ligaments pathology

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https://www.readbyqxmd.com/read/28812037/a-retrospective-analysis-of-concurrent-pathology-in-acl-reconstructed-knees-of-elite-alpine-ski-racers
#1
Matthew J Jordan, Patricia Doyle-Baker, Mark Heard, Per Aagaard, Walter Herzog
BACKGROUND: Anterior cruciate ligament (ACL) tear is the most frequent injury in alpine ski racing, and there is a high prevalence of ACL reinjury. Limited data exist on the concurrent pathology with primary ACL tears in elite alpine ski racers and the magnitude of injury progression after primary ACL reconstruction (ACLR). PURPOSE: To evaluate (1) the involvement of intra-articular and multiligament pathologies at the time of primary ACLR, (2) the subsequent progression in meniscal/chondral injuries, and (3) the occurrence of ACL reinjury in elite alpine ski racers...
July 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28809636/-arthroscopic-finding-of-knee-joint-in-relation-to-age-and-its-comparison-with-pre-operative-clinical-finding-a-retrospective-study
#2
P Látal, K Šimeček, M Kloub
PURPOSE OF THE STUDY In the retrospective study of two South Bohemian centres we present the comparison of pre-operative anamnestic clinical signs in relation to the arthroscopic intraoperative finding. The obtained data is used also to evaluate the arthroscopic finding in relation to age and sex. MATERIAL AND METHODS The arthroscopic findings of patients who underwent surgery in 2013-2014 period (1.1.2013-31.12.2014) at the Department of Trauma Surgery of České Budějovice Hospital, a.s. and in 2014 (1.1...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28768528/safety-tolerability-clinical-and-joint-structural-outcomes-of-a-single-intra-articular-injection-of-allogeneic-mesenchymal-precursor-cells-in-patients-following-anterior-cruciate-ligament-reconstruction-a-controlled-double-blind-randomised-trial
#3
Yuanyuan Wang, Andrew Shimmin, Peter Ghosh, Paul Marks, James Linklater, David Connell, Stephen Hall, Donna Skerrett, Silviu Itescu, Flavia M Cicuttini
BACKGROUND: Few clinical trials have investigated the safety and efficacy of mesenchymal stem cells for the management of post-traumatic osteoarthritis. The objectives of this pilot study were to determine the safety and tolerability and to explore the efficacy of a single intra-articular injection of allogeneic human mesenchymal precursor cells (MPCs) to improve clinical symptoms and retard joint structural deterioration over 24 months in patients following anterior cruciate ligament (ACL) reconstruction...
August 2, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28760559/how-to-measure-responses-of-the-knee-to-lateral-perturbations-during-gait-a-proof-of-principle-for-quantification-of-knee-instability
#4
Josien C van den Noort, Lizeth H Sloot, Sjoerd M Bruijn, Jaap Harlaar
Knee instability is a major problem in patients with anterior cruciate ligament injury or knee osteoarthritis. A valid and clinically meaningful measure for functional knee instability is lacking. The concept of the gait sensitivity norm, the normalized perturbation response of a walking system to external perturbations, could be a sensible way to quantify knee instability. The aim of this study is to explore the feasibility of this concept for measurement of knee responses, using controlled external perturbations during walking in healthy subjects...
July 18, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28735021/wisp1-ccn4-aggravates-cartilage-degeneration-in-experimental-osteoarthritis
#5
M H van den Bosch, A B Blom, V Kram, A Maeda, S Sikka, Y Gabet, T M Kilts, W B van den Berg, P L van Lent, P M van der Kraan, M F Young
OBJECTIVE: Increased Wisp1 expression was previously reported in experimental and human osteoarthritis (OA). Moreover, adenoviral overexpression of Wisp1 in naïve mouse knee joints resulted in early OA-like cartilage lesions. Here, we determined how the matricellular protein WISP1 is involved in the pathology that occurs in the complex osteoarthritic environment with aging and experimental OA in wild type (WT) and Wisp1(-/-) mice. METHODS: WT and Wisp1(-/-) mice were aged or experimental OA was induced with intraarticular collagenase injection, destabilization of the medial meniscus (DMM) or anterior cruciate ligament transection (ACLT)...
July 19, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28714786/effects-of-a-prophylactic-knee-sleeve-on-anterior-cruciate-ligament-loading-during-sport-specific-movements
#6
Jonathan Sinclair, Paul John Taylor
CONTEXT: Prophylactic knee bracing is extensively utilized in athletic populations, to reduce the high risk from knee injuries, but their role in the attenuation of anterior cruciate ligament (ACL) pathologies is not well understood. OBJECTIVE: The aim of the current investigation was to investigate the effects of a prophylactic knee sleeve on ACL loading parameters linked to the aetiology of injury in recreational athletes. SETTING: Laboratory...
July 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28702800/anterolateral-ligament-injuries-in-knees-with-an-anterior-cruciate-ligament-tear-contribution-of-ultrasonography-and-mri
#7
Marie Faruch Bilfeld, Etienne Cavaignac, Karine Wytrykowski, Olivia Constans, Franck Lapègue, Hélène Chiavassa Gandois, Ahmed Larbi, Nicolas Sans
OBJECTIVES: To describe the pathological appearance of the anterolateral ligament (ALL) on US and MRI in knees with an anterior cruciate ligament (ACL) tear. METHODS: This prospective study included 30 patients who had a suspected acute ACL tear. Their injured and contralateral knees were evaluated with radiography, US and MRI. Two radiologists evaluated the ALL on the MRI and US examinations. Agreement between these examiners' findings was evaluated with Cohen's kappa...
July 12, 2017: European Radiology
https://www.readbyqxmd.com/read/28642979/-medial-opening-wedge-high-tibial-osteotomy
#8
REVIEW
P Niemeyer, A Stöhr, M Köhne, A Hochrein
OBJECTIVE: Reduction of the load to the medial compartment in patients with medial knee osteoarthritis and varus malalignment. Unloading of the posterolateral complex in varus deformity with complex ligamentous laxity. INDICATIONS: Medial knee osteoarthritis and varus malalignment with largely intact lateral and patellofemoral joint aspect. Complex ligament insufficiency combined with varus deformity. CONTRAINDICATIONS: Substantially impaired range of motion...
August 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28608618/bench-to-bedside-bridge-enhanced-anterior-cruciate-ligament-repair
#9
REVIEW
Gabriel S Perrone, Benedikt L Proffen, Ata M Kiapour, Jakob T Sieker, Braden C Fleming, Martha M Murray
Anterior cruciate ligament (ACL) injuries are one of the most well-known orthopaedic injuries and are treated with one of the most common orthopaedic procedures performed in the United States. This surgical procedure, ACL reconstruction, is successful at restoring the gross stability of the knee. However, the outcomes of ACL reconstruction can be limited by short and long-term complications, including muscle weakness, graft rupture, and premature osteoarthritis. Thus, new methods of treating this injury are being explored...
June 13, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28607768/platelet-rich-plasma-prp-for-knee-disorders
#10
REVIEW
Mohammad Shahid, Rik Kundra
Platelet-rich plasma (PRP) is an autologous blood product with platelet concentrations above baseline values. The process involves the extraction of blood from the patient which is then centrifuged to obtain a concentrated suspension of platelets by plasmapheresis. It then undergoes a two-stage centrifugation process to separate the solid and liquid components of the anticoagulated blood. PRP owes its therapeutic use to the growth factors released by the platelets which are claimed to possess multiple regenerative properties...
January 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28603610/does-additional-reconstruction-of-the-anterolateral-ligament-during-a-primary-anterior-cruciate-ligament-reconstruction-affect-tibial-rotational-laxity-a-case-series
#11
Rohi Shah, Runveer Singh, Clodagh Dugdale, Guido Geutjens
BACKGROUND: The current evidence suggests that rotational stability in not restored in patients with anterior cruciate ligament (ACL) ruptures, despite reconstructive surgery. The graded pivot-shift is a useful clinical test to delineate extent of ligamentous laxity within the knee. Given its lateralised position, we hypothesized that reconstruction of the anterolateral ligament (ALL) would provide restraint to excessive internal rotation, restoring rotational stability. METHODS: 10 patients with MRI confirmed diagnosis of an isolated ACL rupture were included...
July 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28597058/-flexion-and-extension-osteotomy-of-the-knee
#12
T Diermeier, A B Imhoff, K Beitzel
OBJECTIVES: Flexion and extension osteotomy of the knee for symptomatic malalignment in the sagittal plane. INDICATIONS: Congenital/posttraumatic bony deficiencies in flexion/pathologic hyperextension in the knee. Additional treatment for ligament reconstruction. CONTRAINDICATIONS: Absolute: Infection, critical soft tissue situation, circulatory disorders. Relative: Osteoporosis, heavy smoker, obesity, reduced patient compliance. SURGICAL TECHNIQUE: Diagnostic arthroscopy of the knee...
August 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28585993/a-modified-lateral-approach-for-total-knee-replacement-in-type-2-valgus-deformity
#13
Matthias Aurich, Mark Lenz, Norman Best
Total knee replacement for patients with osteoarthritis and valgus deformity remains challenging, with soft tissue balance often difficult to achieve. Most orthopedic surgeons use the medial parapatellar approach for total knee replacement. However, the lateral approach described in this case allows direct access to the pathology. The valgus deformity is corrected by using a modified lateral parapatellar arthrotomy with a staged and gradual release of the contracted lateral capsuloligamentous structures and the iliotibial tract...
June 6, 2017: Orthopedics
https://www.readbyqxmd.com/read/28580257/posterior-surgical-approach-to-the-knee
#14
Scott C Faucett, James Gannon, Jorge Chahla, Marcio B Ferrari, Robert F LaPrade
Posterior knee approaches are reliable techniques to address the treatment of various pathologies of the posterior region of the knee, including Baker cyst excision, tibial plateau fracture fixation, posterior cruciate ligament avulsions and inlay reconstructions, femoral condyle cartilage procedures, posterior meniscal repair and loose body removal among others. Surgery in the posterior knee region can be challenging because of the presence of neurovascular structures including the tibial nerve, popliteal artery and vein, and common peroneal nerve; thus, it is less commonly performed...
April 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28580251/multiligament-reconstruction-of-the-knee-in-the-setting-of-knee-dislocation-with-a-medial-sided-injury
#15
Marcio B Ferrari, Jorge Chahla, Justin J Mitchell, Gilbert Moatshe, Jacob D Mikula, Daniel Cole Marchetti, Robert F LaPrade
Multiple ligament knee injuries are complex pathologies that often result from traumatic knee dislocations. Both a high level of suspicion and a thorough clinical and radiographic examination are mandatory to diagnose and identify all injured structures. Reconstruction of all injured ligaments is recommended to aid in early mobilization and to avoid joint stiffness or graft failure. For knee dislocations involving injury to the anterior cruciate ligament, posterior cruciate ligament, and medial-sided structures, a repair and augmentation of the medial collateral ligament, together with an anatomic reconstruction of the anterior cruciate ligament and double-bundle posterior cruciate ligament, is recommended...
April 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28567341/technical-note-anterior-cruciate-ligament-reconstruction-in-the-presence-of-an-intramedullary-femoral-nail-using-anteromedial-drilling
#16
Matthew Lacey, Joseph Lamplot, Kempland C Walley, Joseph P DeAngelis, Arun J Ramappa
AIM: To describe an approach to anterior cruciate ligament (ACL) reconstruction using autologous hamstring by drilling via the anteromedial portal in the presence of an intramedullary (IM) femoral nail. METHODS: Once preoperative imagining has characterized the proposed location of the femoral tunnel preparations are made to remove all of the hardware (locking bolts and IM nail). A diagnostic arthroscopy is performed in the usual fashion addressing all intra-articular pathology...
May 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28520463/a-preclinical-assessment-of-early-continuous-passive-motion-and-treadmill-therapeutic-exercises-for-generating-chondroprotective-effects-after-anterior-cruciate-ligament-rupture
#17
Nai-Jen Chang, Kuan-Wei Lee, Chih-Jou Chu, Ming-You Shie, Pei-Hsi Chou, Chih-Chan Lin, Peir-In Liang
BACKGROUND: Anterior cruciate ligament (ACL) injury is a well-known risk factor for the development of posttraumatic osteoarthritis (PTOA). However, whether using continuous passive motion (CPM) with or without additional treadmill exercise (TRE) in early ACL injury might provide chondroprotective effects and further decrease the risk of PTOA has yet to be determined. HYPOTHESIS: CPM may offer an enhanced chondroprotective effect, but TRE may attenuate that effect due to the mechanical stress on the joint and inflammatory cytokines in the joint...
August 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28457606/combined-measurement-and-modeling-of-specimen-specific-knee-mechanics-for-healthy-and-acl-deficient-conditions
#18
Azhar A Ali, Michael D Harris, Sami Shalhoub, Lorin P Maletsky, Paul J Rullkoetter, Kevin B Shelburne
Quantifying the mechanical environment at the knee is crucial for developing successful rehabilitation and surgical protocols. Computational models have been developed to complement in vitro studies, but are typically created to represent healthy conditions, and may not be useful in modeling pathology and repair. Thus, the objective of this study was to create finite element (FE) models of the natural knee, including specimen-specific tibiofemoral (TF) and patellofemoral (PF) soft tissue structures, and to evaluate joint mechanics in intact and ACL-deficient conditions...
May 24, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28455730/knee-abduction-affects-greater-magnitude-of-change-in-acl-and-mcl-strains-than-matched-internal-tibial-rotation-in-vitro
#19
Nathaniel A Bates, Rebecca J Nesbitt, Jason T Shearn, Gregory D Myer, Timothy E Hewett
BACKGROUND: Anterior cruciate ligament (ACL) injures incur over USD 2 billion in annual medical costs and prevention has become a topic of interest in biomechanics. However, literature conflicts persist over how knee rotations contribute to ACL strain and ligament injury. To maximize the efficacy of ACL injury prevention, the effects of underlying mechanics need to be better understood. QUESTIONS/PURPOSES: We applied robotically controlled, in vivo-derived kinematic stimuli to the knee to assess ligament biomechanics in a cadaver model...
April 28, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28436958/local-clearance-of-senescent-cells-attenuates-the-development-of-post-traumatic-osteoarthritis-and-creates-a-pro-regenerative-environment
#20
Ok Hee Jeon, Chaekyu Kim, Remi-Martin Laberge, Marco Demaria, Sona Rathod, Alain P Vasserot, Jae Wook Chung, Do Hun Kim, Yan Poon, Nathaniel David, Darren J Baker, Jan M van Deursen, Judith Campisi, Jennifer H Elisseeff
Senescent cells (SnCs) accumulate in many vertebrate tissues with age and contribute to age-related pathologies, presumably through their secretion of factors contributing to the senescence-associated secretory phenotype (SASP). Removal of SnCs delays several pathologies and increases healthy lifespan. Aging and trauma are risk factors for the development of osteoarthritis (OA), a chronic disease characterized by degeneration of articular cartilage leading to pain and physical disability. Senescent chondrocytes are found in cartilage tissue isolated from patients undergoing joint replacement surgery, yet their role in disease pathogenesis is unknown...
June 2017: Nature Medicine
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