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urology and Transplantation

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https://www.readbyqxmd.com/read/29108916/an-evidence-based-protocol-for-antibiotic-use-prior-to-cystoscopy-decreases-antibiotic-usage-without-impacting-post-procedural-symptomatic-urinary-tract-infection-rates
#1
Justin R Gregg, Rohan G Bhalla, J Paul Cook, Caroline Lai, Roger Dmochowski, Thomas R Talbot, Daniel A Barocas
PURPOSE: Symptomatic urinary tract infection (UTI) is a complication of office-based cystourethroscopy. Studies are mixed regarding the efficacy of antibiotic prophylaxis for UTI prevention. Our aim was to develop and evaluate an evidence-based protocol that reduces unnecessary antibiotic use while avoiding an increase in UTI. MATERIALS AND METHODS: A clinic antibiogram was created based on all urology office visits performed during a two-year time period. Bacterial resistance rates, institutional risk-related data, and clinical guidelines were used to create a protocol for pre-cystourethroscopy antibiotic use...
November 3, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29108517/inferior-long-term-outcomes-for-kidney-transplant-recipients-with-an-immunologically-mediated-primary-renal-disease
#2
Evaldo Favi, José Alberto Rodrigues Pedroso, Maria Paola Salerno, Gionata Spagnoletti, Jacopo Romagnoli, Franco Citterio
OBJECTIVES: Recurrent glomerulonephritis can negatively affect kidney allograft survival. However, how primary renal disease affects transplant outcomes in the new era of immunosuppression remains unclear. MATERIALS AND METHODS: We categorized 426 kidney transplant recipients (performed from 1996 to 2007) into 4 disease groups: (1) 99 recipients with biopsy-proven immunologically mediated kidney disease, (2) 40 recipients with urologic disease, (3) 67 recipients with polycystic kidney disease, and (4) 220 recipients with other causes of terminal renal failure/uncertain kidney disease...
October 31, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29082641/risk-factors-for-urological-complications-following-living-donor-renal-transplantation-in-children
#3
Mohammed S ElSheemy, Waleed Ghoneima, Waseem Aboulela, Kareem Daw, Ahmed M Shouman, Ahmed I Shoukry, Sherif Soaida, Doaa M Salah, Hafez Bazaraa, Fatina I Fadel, Ahmed A Hussein, Enmar Habib, Ismail R Saad, Mohamed El Ghoneimy, Hany A Morsi, Mohammed A Lotfi, Hesham Badawy
The aim of this study was to detect possible risk factors for UC and UTI following pediatric renal Tx and effect of these complications on outcome. One hundred and eight children who underwent living donor Tx between 2009 and 2015 were retrospectively included. Extraperitoneal approach was used with stented tunneled extravesical procedure. Mean recipient age was 9.89 ± 3.46 years while mean weight was 25.22 ± 10.43 kg. Seventy-three (67.6%) recipients were boys while 92 (85.2%) were related to donors...
October 29, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29080255/how-to-stent-the-ureter-after-kidney-transplantation-in-children-a-comparison-of-two-methods-of-urinary-drainage
#4
Anuradha S Ter Haar, Rulan S Parekh, Ralph W J Leunissen, Joop van den, Armando J Lorenzo, Diane Hebert, Mandy G Keijzer-Veen, Karlien Cransberg
Ureteral stenting after pediatric renal transplantation serves to prevent obstruction and urinary leakage, but can also cause complications. This study compares the complication rates of both methods. Data were retrospectively collected at Erasmus MC, Rotterdam, the Netherlands (splint group, n = 61) and Hospital for Sick Children, Toronto, Canada (JJ catheter group, n = 50). Outcome measures included urological interventions and incidence of UTIs during the first 3 months post-transplantation. The splint was removed after a median of 9 (IQR 8-12), the JJ catheter after 42 (IQR 36-50) days...
October 27, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29058024/management-of-renal-transplant-urolithiasis-a-multicentre-study-by-the-french-urology-association-transplantation-committee
#5
J Branchereau, M O Timsit, Y Neuzillet, T Bessède, R Thuret, M Gigante, X Tillou, R Codas, J Boutin, A Doerfler, F Sallusto, T Culty, V Delaporte, N Brichart, B Barrou, L Salomon, G Karam, J Rigaud, L Badet, F Kleinklauss
PURPOSE: Urolithiasis is rare among renal transplant recipients and its management has not been clearly defined. METHODS: This multicentre retrospective study was organised by the Comité de Transplantation de l'Association Française d'Urologie (French Urology Association transplantation committee). Statistical analysis was performed with SPSS 19 software. RESULTS: Ninety-five patients were included in this study. Renal transplant urolithiasis was an incidental finding in 55% of cases, mostly on a routine follow-up ultrasound examination...
October 22, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29039889/robot-assisted-single-port-radical-nephrectomy-and-cholecystectomy-description-and-technical-aspects
#6
Francisco Hidelbrando Alves Mota Filho, Luis Felipe Sávio, Rafael Eiji Sakata, Renato Fidelis Ivanovic, Marco Antonio Nunes da Silva, Ronaldo Maia, Carlo Passerotti
INTRODUCTION: Robot-Assisted Single Site Radical Nephrectomy (RASS-RN) has been reported by surgeons in Europe and United States (1-3). To our best knowledge this video presents the first RASS-RN with concomitant cholecystectomy performed in Latin America. CASE: A 66 year-old renal transplant male due to chronic renal failure presented with an incidental 1.3cm nodule in the upper pole of the right kidney. In addition, symptomatic gallbladder stones were detected...
October 17, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28985026/urologic-malignancies-in-kidney-transplantation
#7
Laura A Hickman, Deirdre Sawinski, Thomas Guzzo, Jayme E Locke
With advances in immunosuppression, graft and patient outcomes after kidney transplantation have improved considerably. As a result, long-term complications of transplant, such as urologic malignancies, have become increasingly important. Kidney transplant recipients, for example, have a seven-fold risk of renal cell carcinoma (RCC) and three-fold risk of urothelial carcinoma (UC) compared to the general population. While extrapolation of data from the general population suggest that routine cancer screening in transplant recipients would allow for earlier diagnosis and management of these potentially lethal malignancies, currently there is no consensus for post-transplant RCC or UC screening as supporting data are limited...
October 6, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28952922/renal-transplant-in-abnormal-bladder-treatment-options-and-their-effects-on-graft-outcome
#8
Baher Salman, Ahmed Hassan, Mohamed Selim, Tarek Abdelbaky, Sultan Sultan, Ahmed Halawa
OBJECTIVES: Correction of structural urologic disorders and optimization of emptying and storage function of the bladder should be achieved before renal transplant in patients with abnormal urinary bladders to protect the new transplanted kidney. The aim of this study was to determine the outcomes of renal transplant among the differently treated abnormal bladder patients. MATERIALS AND METHODS: This was a retrospective study of 30 renal transplant recipients with abnormal bladders who were divided into 2 groups based on abnormal bladder management...
September 26, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28911808/renal-transplantation-after-treatment-for-a-urological-cancer-who-and-when-does-evidence-help-for-a-challenge
#9
EDITORIAL
Javier Burgos-Revilla, Victoria Gomez-Dos-Santos
No abstract text is available yet for this article.
September 11, 2017: European Urology
https://www.readbyqxmd.com/read/28889385/the-n-butyl-n-4-hydroxybutyl-nitrosamine-mouse-urinary-bladder-cancer-model
#10
Paula A Oliveira, Cármen Vasconcelos-Nóbrega, Rui M Gil da Costa, Regina Arantes-Rodrigues
Urinary bladder cancer (UBC) is a common and complex malignancy, with a multifactorial etiology, like environmental factors, such as cigarette smoking, occupational exposure, and genetic factors.UBC exhibits considerable genotypic and phenotypic heterogeneity. Among all UBC lesions, urothelial carcinoma is the most frequently observed histological type. Despite all the developments made in urologic oncology field, therapeutic options remain inadequate. There is urgency for the identification and development of new antineoplastic drugs to replace or improve current protocols and in vivo models have been proven to be essential for this step...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28887865/plasma-rich-plasma-the-ultimate-secret-for-youthful-skin-elixir-and-hair-growth-triggering
#11
REVIEW
Ebtisam Elghblawi
The clinical application of platelet-rich plasma (PRP) is based on the increase in the concentration of growth factors that are released from alpha-granule of the concentrated platelets and in the secretion of proteins which are able to capitalize on the healing process at the cellular level. It has been invented to restore the natural beauty by starting the natural rejuvenation process of the skin and aiming to make it function as a younger one and to keep the skin youthful and maintain it. Besides that, it is also emerged to include hairs as a new injectable procedure to enable stimulating hair growth locally and topically; preventing its fall; improving hair shaft, hair stem, and its caliber; increasing its shine, vitality, and pliability; and declining hair splitting and breakage...
September 8, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28884476/probiotics-for-preventing-urinary-tract-infection-in-people-with-neuropathic-bladder
#12
REVIEW
Swee-Ling Toh, Claire L Boswell-Ruys, Bon San B Lee, Judy M Simpson, Kate R Clezy
BACKGROUND: Neuropathic or neurogenic bladder describes a process of dysfunctional voiding as the result of injury in the brain, spinal cord or nerves innervating the bladder. People with neuropathic bladder, such as from spinal cord injury (SCI), are at significant risk of morbidity from urinary tract infections (UTI). Effective methods to prevent UTI in people with SCI have been sought for many years. Probiotics (micro-organisms that exert beneficial health effects in the host) have been recommended for bacterial interference of the urological tract to reduce colonisation by uropathogen and to manage the dual problems of infection and antibiotic resistance...
September 8, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28838448/inguinal-bladder-hernia-with-acute-ureteral-obstruction-14-years-after-kidney-transplantation-a-case-report
#13
E Ghielmini, L Julita, Y Cerantola, M Matter, T Zingg
An 82-year-old man with a history of renal transplantation 14 years earlier presented with acute obstructive renal failure secondary to inguinal herniation of the urinary bladder complicated by ureteroneocystostomy entrapment. After percutaneous nephrostomy tube and endoscopic stent placement, the bladder was reduced and the hernia repaired with the use of a preperitoneal mesh. The postoperative course was uneventful and the renal function returned to normal. Inguinal herniation of the transplant ureter is a rare cause of hydronephrosis, but it has been described in the literature...
September 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28834044/urological-complications-following-unstented-pediatric-renal-transplantation
#14
Patrick Opoku Manu Maison, Shaun Smit, Mignon McCulloch, Priya Gajjar, Peter Nourse, Dave Thomson, Elmi Muller, Alastair Millar, Alp Numanoglu, Delawir Kahn, John Lazarus
Urological complications which develop post-renal transplantation can be associated with significant morbidity especially in children. We evaluated the occurrence and management of all urological complications in a series of unstented pediatric renal transplants in a tertiary pediatric hospital. We reviewed the medical records of children who underwent unstented renal transplant between January 1996 and December 2014. Postoperative urological complications and the outcomes of their management were analyzed...
November 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28803033/the-risk-of-tumour-recurrence-in-patients-undergoing-renal-transplantation-for-end-stage-renal-disease-after-previous-treatment-for-a-urological-cancer-a-systematic-review
#15
REVIEW
Romain Boissier, Vital Hevia, Harman Max Bruins, Klemens Budde, Arnaldo Figueiredo, Enrique Lledó-García, Jonathon Olsburgh, Heinz Regele, Claire Fraser Taylor, Rhana Hassan Zakri, Cathy Yuhong Yuan, Alberto Breda
CONTEXT: Renal transplantation is the gold standard renal replacement therapy in end-stage renal disease owing to its superior survival and quality of life compared with dialysis. When the potential recipient has a history of cancer, the waiting period before renal transplantation is usually based on the Cincinnati Registry. OBJECTIVE: To systematically review all available evidence on the risk of cancer recurrence in end-stage renal disease patients with a history of urological cancer...
August 10, 2017: European Urology
https://www.readbyqxmd.com/read/28795012/chronic-kidney-disease-and-sports-participation-by-children-and-adolescents
#16
REVIEW
Vimal Master Sankar Raj, Dilip R Patel, Lakshmi Ramachandran
Individuals suffering from chronic kidney disease (CKD) deal with major morbidity and mortality including poor exercise tolerance. A variety of factors including anemia, poor muscle mass, cardiovascular changes and limited physical activity contribute to exercise intolerance. Studies suggest that early initiation of aerobic and resistance training improves the muscle function, ability to tolerate exercise and quality of life in CKD patients. A thorough medical examination and exercise testing are recommended before initiating an exercise regimen in individuals with CKD...
July 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28760118/renal-transplant-in-the-abnormal-bladder-long-term-follow-up
#17
Baher Salman, Ahmed Hassan, Sultan Sultan, Paul Tophill, Ahmed Halawa
OBJECTIVES: Normal urinary bladder stores urine at low pressure, does not leak, and completely empties by natural voiding. An abnormal bladder may be due to neurologic or urologic disorders that render the bladder of small capacity, of high storage pressure, or of poor compliance. The aim of this study was to determine the long-term outcomes of renal transplant in patients with abnormal bladders. MATERIALS AND METHODS: We retrospectively compared 30 transplanted kidneys in 25 patients with abnormal bladders with a control group comprising 30 grafts transplanted simultaneously during the same period of time (1990-2014) in 30 patients without bladder abnormality...
July 31, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28754533/benefits-and-harms-of-treatment-of-asymptomatic-bacteriuria-a-systematic-review-and-meta-analysis-by-the-european-association-of-urology-urological-infection-guidelines-panel
#18
Bela Köves, Tommaso Cai, Rajan Veeratterapillay, Robert Pickard, Thomas Seisen, Thomas B Lam, Cathy Yuhong Yuan, Franck Bruyere, Florian Wagenlehner, Riccardo Bartoletti, Suzanne E Geerlings, Adrian Pilatz, Benjamin Pradere, Fabian Hofmann, Gernot Bonkat, Björn Wullt
People with asymptomatic bacteriuria (ABU) are often unnecessarily treated with antibiotics risking adverse effects and antimicrobial resistance. We performed a systematic review to determine any benefits and harms of treating ABU in particular patient groups. Relevant databases were searched and eligible trials were assessed for risk-of-bias and Grading of Recommendations, Assessment, Development and Education quality. Where possible, a meta-analysis of extracted data was performed or a narrative synthesis of the evidence was presented...
July 25, 2017: European Urology
https://www.readbyqxmd.com/read/28723471/urinary-tract-infections-in-immunocompromised-patients-with-diabetes-chronic-kidney-disease-and-kidney-transplant
#19
REVIEW
Zafer Tandogdu, Tommaso Cai, Bela Koves, Florian Wagenlehner, Truls Erik Bjerklund-Johansen
CONTEXT: This paper provides a brief overview of urinary tract infections (UTIs) in immunocompromised patients from the perspective of a practicing urologist. OBJECTIVE: The primary objective was to provide an update on UTIs in immunocompromised patients. Diabetes mellitus (DM), chronic kidney disease, and kidney transplant (KT) are the most common clinical cases encountered by urologists. Diagnosis, management, and future research needs are summarised. EVIDENCE ACQUISITION: We conducted a nonsystematic review of the literature...
October 2016: European Urology Focus
https://www.readbyqxmd.com/read/28698733/chronic-renal-failure-secondary-to-unrecognized-neurogenic-bladder-in-a-child-with-myelodysplasia
#20
Shameem Ahmed, Siba Prosad Paul
Myelodysplasia includes a group of developmental anomalies resulting from defects that occur during neural tube closure. Urological morbidity in patients with myelodysplasia is significant and if not treated appropriately in a timely manner can potentially lead to progressive renal failure, requiring dialysis or transplantation. We report the case of a 13-year old girl with neurogenic bladder who presented chronic renal failure secondary to lipomyelomeningocele with retethering of cord. She was managed with urinary indwelling catheterization until optimization of renal function and then underwent detethering of cord with excision and repair of residual lipomeningomyelocele...
2017: Iranian Journal of Child Neurology
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