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https://www.readbyqxmd.com/read/28215179/development-of-a-definition-for-the-alcohol-hangover-consumer-descriptions-and-expert-consensus
#1
Marith Van Schrojenstein Lantman, A J A E van de Loo, Marlou Mackus, Joris C Verster
Up to now there is no adequate definition of the alcohol hangover. The purpose of the current study was to develop a useful definition, and consensus among those who will use it in scientific publications. A survey was conducted among N=1099 social drinkers who recently had a hangover. They were asked to provide their definition of the alcohol hangover. Text mining and content analysis revealed 3 potential definitions. These were submitted to members of the Alcohol Hangover Research Group, who were asked to give their expert opinion on the proposed definitions...
16, 2017: Current Drug Abuse Reviews
https://www.readbyqxmd.com/read/28178589/the-breathtaking-truth-about-breath-alcohol-readings-of-zero
#2
Joris C Verster, Marlou Mackus, Aurora Jae van de Loo, Johan Garssen, Andrew Scholey
INTRODUCTION: It has been postulated that the hangover state starts when breath alcohol concentration is zero. METHODS: Data from 2 studies that assessed ethanol in breath, blood and urine were compared. RESULTS: The data revealed that ethanol may still be present in the blood and urine during the hangover state, despite breath analyser readings of zero. DISCUSSION: As ethanol is still present in the body despite zero breath alcohol readings, the current consensus to postpone cognitive testing in hangover studies until breath alcohol concentration is zero should be reconsidered...
January 21, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28176621/a-review-of-the-physiological-factors-associated-with-alcohol-hangover
#3
Celeste Tipple, Sarah Michelle Benson, Andrew Scholey
Alcohol hangovers are a commonly experienced consequence of drinking and are frequently associated with worsened mood and cognitive functioning. The physiological changes that occur with an alcohol-induced hangover state are largely unknown. This review focuses on key physiological factors of an alcohol-induced hangover, more specifically, oxidative stress, lack of sleep, hormonal fluctuations, dehydration, headaches, fever and changes to the immune system. Increased understanding of the relationship between the physiological factors and symptoms of a hangover is needed to further elucidate the mechanisms of an alcohol-induced hangover and potentially identify a treatment...
February 7, 2017: Current Drug Abuse Reviews
https://www.readbyqxmd.com/read/28093029/low-doses-of-mirtazapine-or-quetiapine-for-transient-insomnia-a-randomised-double-blind-cross-over-placebo-controlled-trial
#4
Julie Karsten, Loes A Hagenauw, Jeanine Kamphuis, Marike Lancel
Low doses of the antidepressant mirtazapine or the neuroleptic quetiapine are often prescribed off-label for insomnia. However, studies on the effects on sleep and hangover effects the following day are scarce. In this randomised, double-blind, cross-over, placebo-controlled trial, the influence of 7.5 mg mirtazapine and 50 mg quetiapine on both normal sleep and sleep disturbed by acoustic stress (traffic noise) as a model for transient insomnia was assessed. Additionally, hangover effects on next-day alertness and cognitive functioning were examined...
January 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28077351/a-new-year-hangover-the-nhs-can-t-shake-off
#5
Nigel Edwards
No abstract text is available yet for this article.
January 11, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28076795/hangover-links-nuclear-rna-signaling-to-camp-regulation-via-the-phosphodiesterase-4d-ortholog-dunce
#6
Manuela Ruppert, Mirjam Franz, Anastasios Saratsis, Laura Velo Escarcena, Oliver Hendrich, Li Ming Gooi, Isabell Schwenkert, Ansgar Klebes, Henrike Scholz
The hangover gene defines a cellular stress pathway that is required for rapid ethanol tolerance in Drosophila melanogaster. To understand how cellular stress changes neuronal function, we analyzed Hangover function on a cellular and neuronal level. We provide evidence that Hangover acts as a nuclear RNA binding protein and we identified the phosphodiesterase 4d ortholog dunce as a target RNA. We generated a transcript-specific dunce mutant that is impaired not only in ethanol tolerance but also in the cellular stress response...
January 10, 2017: Cell Reports
https://www.readbyqxmd.com/read/28057196/financial-crisis-hangover-in-cyprus-tracking-the-demand-for-utilization-of-mental-health-services
#7
P Petrou
No abstract text is available yet for this article.
2017: Public Health
https://www.readbyqxmd.com/read/28034278/proceeding-of-the-8th-alcohol-hangover-research-group-meeting
#8
Marlou Mackus, Sally Adams, Amir Barzilay, Sarah Benson, Lauren Blau, Jacqueline Iversen, Sean J Johnson, Ali Keshavarzian, Andrew Scholey, Gordon S Smith, Constantine Trela, Vatsalya Vatsalya, Joris C Verster
Alcohol hangover is one of the most commonly experienced consequences of alcohol consumption. An alcohol hangover develops as the blood alcohol concentrations (BAC) approaches zero, and is characterized by a general feeling of misery. More insight into the pathology of an alcohol hangover needs to be gained, in order to enhance the understanding of the area, and as a potential contribution to the innovation of a preventative or hangover curing treatment. The Alcohol Hangover Research Group (AHRG) was founded to support the area of alcohol hangover...
December 29, 2016: Current Drug Abuse Reviews
https://www.readbyqxmd.com/read/27895524/characteristics-of-social-drinkers-with-and-without-a-hangover-after-heavy-alcohol-consumption
#9
A Hogewoning, Ajae Van de Loo, M Mackus, S J Raasveld, R De Zeeuw, E R Bosma, N H Bouwmeester, K A Brookhuis, J Garssen, J C Verster
BACKGROUND: A number of social drinkers claim that they do not experience next-day hangovers despite consuming large quantities of alcohol. The aim of this study was to investigate the characteristics of drinkers who claim to be hangover immune and compare them with drinkers who do report having hangovers. METHODS: A total of 36 social drinkers participated in a naturalistic study consisting of a hangover day (alcohol consumed) and a control day (no alcohol consumed)...
2016: Substance Abuse and Rehabilitation
https://www.readbyqxmd.com/read/27860050/characterization-of-hangover-following-intravenous-alcohol-exposure-in-social-drinkers-methodological-and-clinical-implications
#10
Vatsalya Vatsalya, Bethany L Stangl, Veronica Y Schmidt, Vijay A Ramchandani
Hangover refers to the cluster of physiological and behavioral symptoms that occur following the end of a drinking episode. While hangover has been studied after the typical oral consumption of alcohol, the occurrence of hangover following intravenous (IV) alcohol administration in human laboratory studies has not been previously reported. This study characterizes hangover symptoms and post-infusion drinking behavior following acute IV alcohol administration in social drinkers. Twenty-one to thirty-year-old healthy social drinkers (n = 24) underwent an alcohol clamp session at breath alcohol concentration of 0...
November 11, 2016: Addiction Biology
https://www.readbyqxmd.com/read/27807268/cytoplasmic-inheritance-of-parent-offspring-cell-structure-in-the-clonal-diatom-cyclotella-meneghiniana
#11
Yuka Shirokawa, Masakazu Shimada
In cytoplasmic inheritance, structural states of a parent cell could be transmitted to offspring cells via two mechanisms. The first is referred to as the hangover of parent structure, where the structure itself remains and faithfully transmits within offspring cells; the second is structural inheritance, wherein the parent structure functions as a template for development of new offspring structure. We estimated to what extent the parent structure affects the development of offspring structure by structural inheritance, using a clone of the diatom Cyclotella meneghiniana The cell has two siliceous valves (a cell wall part at both cell poles): one is inherited from the parent and the other is newly formed...
November 16, 2016: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/27800672/emergency-departments-and-alcohol-the-perpetual-hangover
#12
Viet Tran, Sara Mackenzie, Suzanne Hamilton, Michael Jr Edmonds, Lisa Brichko
No abstract text is available yet for this article.
December 2016: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/27790802/effects-of-high-dose-ethanol-intoxication-and-hangover-on-cognitive-flexibility
#13
Nicole Wolff, Philipp Gussek, Ann-Kathrin Stock, Christian Beste
The effects of high-dose ethanol intoxication on cognitive flexibility processes are not well understood, and processes related to hangover after intoxication have remained even more elusive. Similarly, it is unknown in how far the complexity of cognitive flexibility processes is affected by intoxication and hangover effects. We performed a neurophysiological study applying high density electroencephalography (EEG) recording to analyze event-related potentials (ERPs) and perform source localization in a task switching paradigm which varied the complexity of task switching by means of memory demands...
October 27, 2016: Addiction Biology
https://www.readbyqxmd.com/read/27678552/urine-ethanol-concentration-and-alcohol-hangover-severity
#14
Aurora Van de Loo, Marlou Mackus, Gerdien Korte-Bouws, Karel Brookhuis, Johan Garssen, Joris Verster
BACKGROUND: The aim of this study was to examine the relationship between urine ethanol concentration and alcohol hangover severity. METHODS: N = 36 healthy social drinkers participated in a naturalistic study, comprising a hangover day and a control day. N = 18 of them have regular hangovers (the hangover group), while the other N = 18 claim to be hangover immune (hangover-immune group). On each test day at 9.30 am, urine samples were collected. Participants rated their overall hangover severity on a scale from 0 (absent) to 10 (extreme), as well as 18 individual hangover symptoms...
January 2017: Psychopharmacology
https://www.readbyqxmd.com/read/27627570/correlates-of-abusing-and-misusing-over-the-counter-pain-relievers-among-adult-population-of-wroc%C3%A5-aw-poland
#15
Monika Wójta-Kempa, Dominik M Krzyżanowski
BACKGROUND: Almost 90% of households in Poland buy medicines on their own initiative. The most popular OTC medicines bought by Polish consumers are painkillers and non-steroid-anti-inflammatory drugs. OBJECTIVES: The aim of this article was to recognize and describe the most important predictive factors of the abuse and misuse of over-the-counter pain relievers among adults in Wrocław (Poland). The groups of users were selected and described. Some examples of misuse were analyzed...
March 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/27515665/the-nociceptin-orphanin-fq-receptor-agonist-sr-8993-as-a-candidate-therapeutic-for-alcohol-use-disorders-validation-in-rat-models
#16
Abdul Maruf Asif Aziz, Shaun Brothers, Gregory Sartor, Lovisa Holm, Markus Heilig, Claes Wahlestedt, Annika Thorsell
RATIONALE: Alcoholism is a complex disorder in which diverse pathophysiological processes contribute to initiation and progression, resulting in a high degree of heterogeneity among patients. Few pharmacotherapies are presently available, and patient responses to these are variable. The nociceptin/orphanin FQ (NOP) receptor has been suggested to play a role both in alcohol reward and in negatively reinforced alcohol seeking. Previous studies have shown that NOP-receptor activation reduces alcohol intake in genetically selected alcohol-preferring as well as alcohol-dependent rats...
October 2016: Psychopharmacology
https://www.readbyqxmd.com/read/27383492/protective-effect-of-heat-treated-cucumber-cucumis-sativus-l-juice-on-alcohol-detoxification-in-experimental-rats
#17
Vivek K Bajpai, Na-Hyung Kim, Ji-Eun Kim, Kangmin Kim, Sun Chul Kang
In this study, heat-treated cucumber juice was assessed for its protective effect on blood alcohol levels and hepatic alcohol metabolic enzyme system in experimental rats. Initially, during detoxification of alcohol, all groups were orally dosed to 22% alcohol (6ml/kg body weight) along with different concentrations of heat-treated cucumber juice (10, 100 and 500mg/kg) and commercial goods for hangover-removal on sale (2ml/kg). Cucumber juice was dosed before 30 min, and simultaneously after 30min of alcohol administration, and its hepatoprotective effect on blood alcohol levels and hepatic alcohol metabolic enzyme system in experimental rats was evaluated...
May 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27339661/assessment-of-withdrawal-and-hangover-is-confounded-in-the-alcohol-use-disorder-and-associated-disabilities-interview-schedule-withdrawal-prevalence-is-likely-inflated
#18
Cassandra L Boness, Sean P Lane, Kenneth J Sher
BACKGROUND: The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV) and AUDADIS-5 are diagnostic interviews used in major epidemiological and other studies of alcohol use disorder (AUD). Much of what we know regarding the prevalence of AUD in the United States is based upon this interview. However, past research and meta-analytic evidence suggest that differential operationalization of the AUD criteria across instruments can lead to differential endorsement of symptoms and resulting AUD diagnosis rates...
August 2016: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/27238886/effects-of-binge-drinking-and-hangover-on-response-selection-sub-processes-a-study-using-eeg-and-drift-diffusion-modeling
#19
Ann-Kathrin Stock, Sven Hoffmann, Christian Beste
Effects of binge drinking on cognitive control and response selection are increasingly recognized in research on alcohol (ethanol) effects. Yet, little is known about how those processes are modulated by hangover effects. Given that acute intoxication and hangover seem to be characterized by partly divergent effects and mechanisms, further research on this topic is needed. In the current study, we hence investigated this with a special focus on potentially differential effects of alcohol intoxication and subsequent hangover on sub-processes involved in the decision to select a response...
May 29, 2016: Addiction Biology
https://www.readbyqxmd.com/read/27220058/carryover-more-than-just-a-major-hangover-for-the-clinical-laboratory
#20
EDITORIAL
Peter A Kavsak, Johannes Zeidler
No abstract text is available yet for this article.
July 2016: Clinical Biochemistry
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