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Sleep apnea nasal obstruction

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https://www.readbyqxmd.com/read/28511831/obstructive-sleep-apnea-and-dermatologic-disorders
#1
Madhulika A Gupta, Fiona C Simpson, Branka Vujcic, Aditya K Gupta
Obstructive sleep apnea (OSA) is present in at least 2% of women and 4% of men, and its prevalence is increasing, because a major predisposing factor for OSA is a high body mass index. Psoriasis has the most strongly substantiated link with OSA, where the relationship may be bidirectional. Dermatologic disorders may be comorbid with OSA due to several factors: (i) the heightened proinflammatory state in OSA, which can occur independent of body mass index, and may exacerbate inflammatory dermatoses; (ii) intermittent hypoxemia may promote neovascularization and tumor growth in certain cancers, such as melanoma; (iii) obesity, present in majority of OSA patients, can be associated with a heightened proinflammatory state; (iv) upper airway obstruction due to local tumors or soft tissue swelling due to physical urticaria or angioedema; (v) acute nasal congestion in the atopic patient with allergic rhinitis; (vi) dermatologic disorders associated with other OSA risk factors (eg, acanthosis nigricans and metabolic syndrome); and (vii) a high sympathetic tone (eg, in atopic dermatitis) and resultant sleep fragmentation contributing to upper airway instability during sleep...
May 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28490347/gh-secreting-pituitary-macroadenoma-acromegaly-associated-with-progressive-dental-malocclusion-and-refractory-cpap-treatment
#2
Jaume Miranda-Rius, Lluís Brunet-LLobet, Eduard Lahor-Soler, David de Dios-Miranda, Josep Anton Giménez-Rubio
BACKGROUND: A link between progressive dental malocclusion, the use of a continuous positive airway pressure mask and GH-secreting pituitary macroadenoma (acromegaly) has not been previously reported. The present clinicopathological analysis stresses that tooth malposition should not be seen exclusively as a local process. CASE PRESENTATION: A 62-year-old caucasian man with no relevant medical history reported difficulty chewing food and perceived voice alteration during his annual periodontal check-up...
May 10, 2017: Head & Face Medicine
https://www.readbyqxmd.com/read/28489737/clinical-effect-of-montelukast-sodium-combined-with-inhaled-corticosteroids-in-the-treatment-of-osas-children
#3
Da-Zhi Yang, Jia Liang, Feng Zhang, Hong-Bing Yao, Yan Shu
This study was designed to investigate the clinical effect of montelukast sodium combined with inhaled corticosteroids in the treatment of children with obstructive sleep apnea syndrome (OSAS).One hundred ninety-five children were enrolled and divided into 3 groups: groups A, B, and C; the group A (oral use of montelukast sodium), group B (nasal spray of mometasone furoate), and group C (oral use of montelukast sodium + nasal spray of mometasone furoate). Telephone questionnaire surveys were carried out. Polysomnography monitoring was performed and lateral x-ray radiographs of the cervical spine were taken before treatment and at 12 weeks after treatment...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28468136/craniofacial-deviations-in-the-children-with-nasal-obstruction
#4
Ayca Ant, Yusuf Kemal Kemaloglu, Metin Yilmaz, Alper Dilci
Nasal obstruction mainly caused by adenoid hypertrophy in children affects the craniofacial growth and development process, and the craniofacial deviations and/or differences reported in the children are very similar to those in the adults with obstructive sleep apnea syndrome (OSAS). The authors aimed to look for relationships of the linear craniofacial dimensions in the children suffering from nasal obstruction with age, degree of clinical nasal obstruction score (CNOS), and relative size of the adenoid mass within the nasopharynx in their study...
May 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28457643/risk-of-obstructive-sleep-apnea-in-african-american-patients-with-chronic-rhinosinusitis
#5
Jessica W Hui, Jason Ong, James J Herdegen, Hajwa Kim, Christopher D Codispoti, Vahid Kalantari, Mary C Tobin, Robert P Schleimer, Pete S Batra, Phillip S LoSavio, Mahboobeh Mahdavinia
BACKGROUND: It is widely known that patients with chronic rhinosinusitis (CRS) commonly experience sleep disruption. Many of these patients have the associated diagnosis of obstructive sleep apnea (OSA). However, little is known about the risk factors for developing OSA in the CRS population. OBJECTIVE: To identify the risk factors for OSA in CRS to determine who should be screened for OSA among patients with CRS. METHODS: We evaluated a large cohort of patients with confirmed diagnostic criteria for CRS...
April 27, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28442894/effect-of-adherence-on-daytime-sleepiness-fatigue-depression-and-sleep-quality-in-the-obstructive-sleep-apnea-hypopnea-syndrome-patients-undertaking-nasal-continuous-positive-airway-pressure-therapy
#6
Yeying Wang, Li Ai, Jiahong Luo, Ran Li, Yanlin Chai, Xiaojie He, Yu Cao, Yongxia Li
OBJECTIVES: The aims of this study were to describe changes in day- and nighttime symptoms and the adherence to nasal continuous positive airway pressure (nCPAP) during the first 3-month nCPAP therapy among newly diagnosed patients with obstructive sleep apnea/hypopnea syndrome (OSAS) and to identify the effect of adherence on the changes in day- and nighttime symptoms during the first 3 months. METHODS: Newly diagnosed OSAS patients were consecutively recruited from March to August 2013...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28419356/arousal-induced-hypocapnia-does-not-reduce-genioglossus-activity-in-obstructive-sleep-apnea-arousal-induced-hypocapnia-in-osa-muscle-effects
#7
Jennifer M Cori, Therese Thornton, Fergal J O'Donoghue, Peter D Rochford, David P White, John Trinder, Amy S Jordan
Study Objectives: To determine whether arousals that terminate obstructive events in obstructive sleep apnea (OSA): 1. Induce hypocapnia and 2. Subsequently reduce genioglossus muscle activity following the return to sleep. Methods: 31 untreated OSA patients slept instrumented with: sleep staging electrodes, nasal mask and pneumotachograph, end-tidal CO2 monitoring and intramuscular genioglossus electrodes. End-tidal CO2 was monitored and respiratory arousals were assigned an end-arousal CO2 change value (PETCO2 on the last arousal breath minus each individual's wakefulness PETCO2)...
April 13, 2017: Sleep
https://www.readbyqxmd.com/read/28418014/the-relationship-between-allergic-status-and-adenotonsillar-regrowth-a-retrospective-research-on-children-after-adenotonsillectomy
#8
Zirong Huo, Jun Shi, Yilai Shu, Mingliang Xiang, Jingrong Lu, Hao Wu
Adenotonsillar regrowth in children after adenotonsillectomy (T&A) for obstructive sleep apnea (OSA) is often seen in clinical treatment, however, the relationship between allergic disease and adenotonsillar regrowth remains unclear. In this retrospective study, children were assigned to either the recurrence or control group, and subdivided by age at operation. Among children over 36 months, those in the recurrence group had more allergic disease and higher IgE, IL-4, and IL-5 levels than the same-aged children in control group...
April 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28417661/corrective-nasal-surgery-after-maxillomandibular-advancement-for-obstructive-sleep-apnea-experience-from-379-cases
#9
Stanley Yung-Chuan Liu, Pi-Jung Lee, Michael Awad, Robert W Riley, Soroush Zaghi
Objective Efficacy of maxillomandibular advancement (MMA) in the treatment of obstructive sleep apnea (OSA) is associated with degree of maxillary advancement. Large maxillary advancement leads to profound changes of the nasolabial region. We present the incidence and indications of post-MMA corrective nasal surgery in a large cohort. Study Design Case series with chart review. Setting University medical center. Subjects and Methods A total of 379 subjects with OSA underwent MMA at Stanford Hospital (surgeons: S...
April 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28381324/quality-of-life-improvement-after-endoscopic-sinus-surgery-in-patients-with-obstructive-sleep-apnea
#10
Bobby A Tajudeen, Steven G Brooks, Carol H Yan, Edward C Kuan, Joseph S Schwartz, Jeffrey D Suh, James N Palmer, Nithin D Adappa
BACKGROUND: There is preliminary evidence that patients with chronic rhinosinusitis (CRS) and comorbid obstructive sleep apnea (OSA) have reduced quality-of-life (QOL) improvements after functional endoscopic sinus surgery (FESS) compared with patients without OSA. The effect of OSA severity on QOL improvement after FESS is unknown. OBJECTIVES: To better characterize the QOL improvement after FESS for patients with comorbid OSA and to assess whether QOL improvement is dependent on OSA severity...
March 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28366323/effect-of-continuous-positive-airway-pressure-on-regional-cerebral-blood-flow-in-patients-with-severe-obstructive-sleep-apnea-syndrome
#11
Jeong Sik Kim, Ji Hye Seo, Mi-Ri Kang, Min Jae Seong, Won Gu Lee, Eun Yeon Joo, Seung Bong Hong
OBJECTIVES: Obstructive sleep apnea (OSA) is commonly associated with neural and cognitive deficits induced by recurrent hypoxemia and sleep fragment. The aims of this study were to use statistical parametric mapping (SPM) to analyze changes in regional cerebral blood flow (rCBF) in untreated patients with severe OSA before and after nasal continuous positive airway pressure (CPAP) treatment, examine the impact of OSA-related variables on rCBF, and assess the therapeutic effect of nasal CPAP treatment...
April 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28356182/the-efficacy-of-low-level-continuous-positive-airway-pressure-for-the-treatment-of-snoring
#12
Michelle A Guzman, Francis P Sgambati, Huy Pho, Rafael S Arias, Erin M Hawks, Erica M Wolfe, Tamás Ötvös, Russell Rosenberg, Riad Dakheel, Hartmut Schneider, Jason P Kirkness, Philip L Smith, Alan R Schwartz
STUDY OBJECTIVES: To assess effects of low-level continuous positive airway pressure (CPAP) on snoring in habitual snorers without obstructive sleep apnea (OSA). METHODS: A multicenter prospective in-laboratory reversal crossover intervention trial was conducted between September 2013 and August 2014. Habitual snorers were included if they snored (inspiratory sound pressure level ≥ 40 dBA) for ≥ 30% all sleep breaths on a baseline sleep study (Night 1), and if significant OSA and daytime somnolence were absent...
May 15, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28356172/severe-obstructive-sleep-apnea-in-a-child-with-goldenhar-syndrome-and-nasal-obstruction
#13
Charlie Abraham, Jordan Virbalas, Lourdes M Del Rosso
A 4-year-old boy with Goldenhar syndrome and severe obstructive sleep apnea does not tolerate nasal continuous positive airway pressure. Evaluation with imaging showed nasal obstruction with an inverted tooth. This case illustrates the importance of personalized evaluation and treatment plan in a child with Goldenhar syndrome.
March 28, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28356131/treatment-of-infants-with-syndromic-robin-sequence-with-modified-palatal-plates-a-minimally-invasive-treatment-option
#14
Silvia Müller-Hagedorn, Wolfgang Buchenau, Jörg Arand, Margit Bacher, Christian F Poets
BACKGROUND: Infants with Robin sequence (RS) suffer from upper airway obstruction (UAO) and feeding problems. We developed an oral appliance with a velar extension in combination with functional treatment and appropriate feeding techniques, which was proven effective in isolated RS. As the above problems are particularly challenging in syndromic RS, we set out to evaluate our treatment concept also in these patients. METHODS: We searched our electronic departmental database to identify all children admitted to our department between 01/01/2003 and 31/12/2009 because of syndromic RS...
March 30, 2017: Head & Face Medicine
https://www.readbyqxmd.com/read/28355121/airway-resistance-in-patients-with-obstructive-sleep-apnea-syndrome-following-robotic-prostatectomy
#15
Wiebke Köhne, André Börgers, Michael Musch, Darko Kröpfl, Harald Groeben
BACKGROUND: Because minimally invasive surgery can improve postoperative recovery, it became the preferred technique for patients with significant comorbidities. However, steep Trendelenburg position and abdominal CO2-insufflation can lead to a significant increase in upper airway resistance and an alteration of overall lung function. In particular, patients who already suffer from an obstructive airway disease like obstructive sleep apnea syndrome (OSAS) might be at risk for postoperative airway complications...
May 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28352990/choosing-the-right-interface-for-positive-airway-pressure-therapy-in-patients-with-obstructive-sleep-apnea
#16
REVIEW
Ahmed S BaHammam, Tripat Singh, Smitha George, Karen Lorraine Acosta, Kashmira Barataman, Divinagracia E Gacuan
PURPOSE: Positive airway pressure (PAP) is the standard and most effective treatment for obstructive sleep apnea (OSA). It provides a continuous stream of air under positive pressure through the nose, mouth, or both, which prevents collapse of the upper airway. This allows the patient to breathe freely during sleep. The success of PAP therapy depends largely on the selection of the proper interface (mask). The choice and application of the interface in patients with OSA is a great challenge that greatly affects the long-term compliance to PAP therapy...
March 29, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28294380/oral-appliance-therapy-versus-nasal-continuous-positive-airway-pressure-in-obstructive-sleep-apnoea-syndrome-a-randomised-placebo-controlled-trial-on-self-reported-symptoms-of-common-sleep-disorders-and-sleep-related-problems
#17
M Nikolopoulou, A Byraki, J Ahlberg, M W Heymans, H L Hamburger, J De Lange, F Lobbezoo, G Aarab
Obstructive sleep apnoea syndrome (OSAS) is associated with several sleep disorders and sleep-related problems. Therefore, the aim of this study was to compare the effects of a mandibular advancement device (MAD) with those of nasal continuous positive airway pressure (nCPAP) on self-reported symptoms of common sleep disorders and sleep-related problems in mild and moderate OSAS patients. In this randomised placebo-controlled trial, sixty-four OSAS patients (52·0 ± 9·6 years) were randomly assigned to an MAD, nCPAP or an intra-oral placebo appliance in a parallel design...
June 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28292706/effect-of-airflow-and-material-models-on-tissue-displacement-for-surgical-planning-of-pharyngeal-airways-in-pediatric-down-syndrome-patients
#18
Dhananjay Radhakrishnan Subramaniam, Goutham Mylavarapu, Robert J Fleck, Raouf S Amin, Sally R Shott, Ephraim J Gutmark
Pharyngeal narrowing in obstructive sleep apnea (OSA) results from flow-induced displacement of soft tissue. The objective of this study is to evaluate the effect of airflow parameters and material model on soft tissue displacement for planning surgical treatment in pediatric patients with OSA and Down syndrome (DS). Anatomically accurate, three-dimensional geometries of the pharynx and supporting tissue were reconstructed for one pediatric OSA patient with DS using magnetic resonance images. Six millimeters of adenoid tissue was virtually removed based on recommendations from the surgeon, to replicate the actual adenoidectomy...
March 8, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28289401/sleep-disorders-is-the-trigemino-cardiac-reflex-a-missing-link
#19
REVIEW
Tumul Chowdhury, Barkha Bindu, Gyaninder Pal Singh, Bernhard Schaller
Trigeminal innervated areas in face, nasolacrimal, and nasal mucosa can produce a wide array of cardiorespiratory manifestations that include apnea, bradypnea, bradycardia, hypotension, and arrhythmias. This reflex is a well-known entity called "trigemino-cardiac reflex" (TCR). The role of TCR is investigated in various pathophysiological conditions especially in neurosurgical, but also skull base surgery procedures. Additionally, its significance in various sleep-related disorders has also been highlighted recently...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28281031/pulse-transit-time-as-a-tool-to-characterize-obstructive-and-central-apneas-in-children
#20
Lucie Griffon, Alessandro Amaddeo, Jorge Olmo Arroyo, Rossana Tenconi, Serena Caggiano, Sonia Khirani, Brigitte Fauroux
PURPOSE: The characterization of apneas during polysomnography (PSG) as obstructive or central is a key element of a sleep study. Pulse transit time (PTT) has demonstrated its potential as a noninvasive surrogate marker for inspiratory efforts. The aim of the study was to assess the ability of PTT to classify apneas as central or obstructive, as compared to respiratory inductance plethysmography (RIP) in children. METHODS: Overnight PSG with simultaneous PTT recording was performed on 11 consecutive children (mean age 8...
March 9, 2017: Sleep & Breathing, Schlaf & Atmung
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