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Sleep apnea nasal obstruction

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https://www.readbyqxmd.com/read/27878543/a-new-predictive-model-for-continuous-positive-airway-pressure-in-the-treatment-of-obstructive-sleep-apnea
#1
Matthew R Ebben, Mariya Narizhnaya, Ana C Krieger
BACKGROUND: Numerous mathematical formulas have been developed to determine continuous positive airway pressure (CPAP) without an in-laboratory titration study. Recent studies have shown that style of CPAP mask can affect the optimal pressure requirement. However, none of the current models take mask style into account. Therefore, the goal of this study was to develop new predictive models of CPAP that take into account the style of mask interface. METHODS: Data from 200 subjects with attended CPAP titrations during overnight polysomnograms using nasal masks and 132 subjects using oronasal masks were randomized and split into either a model development or validation group...
November 22, 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/27871083/work-of-breathing-in-fixed-and-pressure-relief-continuous-positive-airway-pressure-c-flex%C3%A2-a-post-hoc-analysis
#2
Lukas Jerrentrup, Sebastian Canisius, Susanne Wilhelm, Karl Kesper, Thomas Ploch, Claus Vogelmeier, Timm Greulich, Heinrich F Becker
BACKGROUND: Expiratory pressure relief continuous positive airway pressure (pressure relief CPAP; C-Flex™) causes increases in inspiratory duty cycle and shortening of expiratory time. It has been suggested that these changes are caused by an increase in work of breathing. OBJECTIVES: We studied the effects of C-Flex on work of breathing and intrinsic positive end-expiratory pressure as compared to fixed CPAP. METHODS: Work of breathing was analyzed in 24 patients with obstructive sleep apnea during treatment with fixed CPAP and C-Flex with 3 different pressure relief settings in a randomized order during rapid-eye-movement (REM) and non-REM sleep...
November 22, 2016: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27854132/changes-of-retinal-nerve-fiber-layer-thickness-in-obstructive-sleep-apnea-syndrome-a-systematic-review-and-meta-analysis
#3
Wei Wang, Miao He, Wenyong Huang
PURPOSE: Many studies have assessed the changes of retinal nerve fiber layer (RNFL) thickness in patients with obstructive sleep apnea syndrome (OSAS), but the results were inconsistent. Therefore, a meta-analysis was performed to evaluate the RNFL changes in OSAS measured in vivo. METHODS: Pertinent studies were identified by a comprehensive search of PubMed, Embase, Web of science, Cochrane library, Scopus, and Chinese biomedical disc databases from inception to August 2016...
November 17, 2016: Current Eye Research
https://www.readbyqxmd.com/read/27837378/nasal-nitric-oxide-improved-by-continuous-positive-airway-pressure-therapy-for-upper-airway-inflammation-in-obstructive-sleep-apnea
#4
Satoshi Hamada, Shuji Tatsumi, Yoshiki Kobayashi, Hirotaka Yasuba
PURPOSE: In this report, we examined the association between obstructive sleep apnea (OSA) and upper and lower airway inflammation based on nitric oxide (NO) measurements. METHODS: Study subjects included 51 consecutive participants. Sleep-disordered breathing was evaluated by a type 3 portable monitor and quantified by respiratory disturbance index (RDI). Airway inflammation was noninvasively analyzed by the measurement of nasally and orally exhaled NO; nasal value was presented as nasally exhaled NO minus orally exhaled NO...
November 12, 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/27827006/did-napoleon-suffer-from-chronic-rhonchopathy
#5
Claude-Henri Chouard
CONCLUSION: If Napoleon had been treated, Europa would then have doubtless been different, and perhaps would not have known the last two World wars. OBJECTIVES: This study plans to demonstrate that Napoleon very probably suffered from Chronic Rhonchopathy. BACKGROUND: Between 1983-1993, the author led their ENT department of CHU Saint-Antoine to contribute in the knowledge of chronic snoring and Obstructive Sleep Apneas Syndrome (OSAS), and to define the treatment of their consequences...
November 9, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27815593/-treating-nasal-obstruction-in-obstructive-sleep-apnea-patients
#6
T Verse, S Wenzel
The impact of treating nasal obstruction in obstructive sleep apnea (OSA) patients is still intensively discussed at congresses. This is likely due to the highly conflicting results of nasal treatments in regard to restorative sleep on the one hand, and their influence on the severity of OSA on the other. Both conservative and surgical nasal treatments result in a highly significant improvement of sleep quality. Patients' sleep is more restorative, which has a huge impact on several quality of life parameters...
November 4, 2016: HNO
https://www.readbyqxmd.com/read/27812636/gel-pillow-designed-specifically-for-obstructive-sleep-apnea-treatment-with-continuous-positive-airway-pressure
#7
Adriana Salvaggio, Anna Lo Bue, Serena Iacono Isidoro, Salvatore Romano, Oreste Marrone, Giuseppe Insalaco
Objective: To determine whether the use of a gel pillow with side cutouts designed to accommodate a continuous positive airway pressure (CPAP) mask and reduce head temperature improves the efficacy of and adherence to auto-CPAP therapy. Methods: Twenty-three consecutive CPAP-naïve patients with obstructive sleep apnea were enrolled in the study. Patients were given an auto-CPAP machine with an appropriate CPAP mask and were instructed to use CPAP for 15 nights...
September 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/27799847/quality-of-life-and-symptoms-before-and-after-nasal-septoplasty-compared-with-healthy-individuals
#8
Vegard Bugten, Ann Helen Nilsen, Wenche Moe Thorstensen, Mads Henrik Strand Moxness, Marit Furre Amundsen, Ståle Nordgård
BACKGROUND: The goal of this study is to compare quality of life (Qol) and symptoms in 91 patients with a deviated nasal septum preoperatively and postoperatively with a control group of 93 healthy individuals. METHODS: All patients reported Qol on Sino-Nasal-Outcome-Test-20 (SNOT-20) and symptoms on visual analogue scale (VAS) preoperatively and 6 months after surgery and the results were compared with the controls. RESULTS: Mean SNOT-20 score improved from 1...
2016: BMC Ear, Nose, and Throat Disorders
https://www.readbyqxmd.com/read/27784404/arousal-intensity-is-a-distinct-pathophysiological-trait-in-obstructive-sleep-apnea
#9
Jason Amatoury, Ali Azarbarzin, Magdy Younes, Amy S Jordan, Andrew Wellman, Danny J Eckert
STUDY OBJECTIVES: Arousals from sleep vary in duration and intensity. Accordingly, the physiological consequences of different types of arousals may also vary. Factors that influence arousal intensity are only partly understood. This study aimed to determine if arousal intensity is mediated by the strength of the preceding respiratory stimulus, and investigate other factors mediating arousal intensity and its role on post-arousal ventilatory and pharyngeal muscle responses. METHODS: Data were acquired in 71 adults (17 controls, 54 obstructive sleep apnea patients) instrumented with polysomnography equipment plus genioglossus and tensor palatini electromyography (EMG), a nasal mask and pneumotachograph, and an epiglottic pressure sensor...
October 20, 2016: Sleep
https://www.readbyqxmd.com/read/27776719/cone-beam-computed-tomography-analysis-of-upper-airway-measurements-in-patients-with-obstructive-sleep-apnea
#10
Suleiman M Momany, Ghaida AlJamal, Bassam Shugaa-Addin, Yousef S Khader
PURPOSE: To explore the validity of cone beam computed tomography (CBCT) as one of many predictive tools that can be used (alone or in conjunction) to help in identifying high-risk cases of obstructive sleep apnea (OSA) that should get the earliest possible referral to a sleep specialist for standard diagnostic polysomnography, and to identify imaging airway parameters that may be predictive of OSA severity. METHODS: Using a case-control design, 45 subjects matched by age and sex (22 OSA cases and 23 controls) were included in this study...
October 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/27775805/craniofacial-morphology-and-airflow-in-children-with-primary-snoring
#11
V Luzzi, G Di Carlo, M Saccucci, G Ierardo, E Guglielmo, M Fabbrizi, A M Zicari, M Duse, F Occasi, G Conti, E Leonardi, A Polimeni
OBJECTIVE: Sleep-disordered breathing (SDB) is among the most common diseases and includes a group of pathological conditions that form a severity continuum from primary snoring (PS) to obstructive sleep apnea (OSA). SDB presents a multifactorial etiology and in children, it is often linked to adenotonsillar hypertrophy, which may lead to an alteration of the breathing pattern. Therefore, several studies hinted at the existence of a correlation between SDB and the alteration of craniofacial growth...
October 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27754829/potential-inflammatory-markers-in-obstructive-sleep-apnea-hypopnea-syndrome
#12
Dongmei Lu, Nanfang Li, Xiaoguang Yao, Ling Zhou
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a complex chronic inflammatory respiratory disease with multiple pathogenic factors and high morbidity and mortality. Serum levels of nuclear factor-κB (NF-κB), hypoxia-inducible factor-1 alpha (HIF-1α), and surfactant protein D (SPD) were investigated in OSAHS patients, to determine their clinical significance and correlation with the pathogenesis. Patients were classified into a mild and moderate OSAHS group (n = 25) and severe OSAHS group (n = 33). Twenty healthy patients served as a control group...
October 18, 2016: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/27720463/nasal-surgery-for-obstructive-sleep-apnea-syndrome
#13
Samuel A Mickelson
Obstructive sleep apnea is a common condition, primarily caused by narrowing of the nasal and pharyngeal airway. Treatment with continuous positive airway pressure (CPAP) is considered the first line of therapy, but long-term compliance is only about 40%, often because of nasal obstruction. Any nasal obstruction can worsen CPAP compliance. Treatment of the nasal obstruction with topical nasal steroid sprays or nasal dilators has been shown to improve sleep disordered breathing. Surgical treatment of nasal obstruction, has been shown to improve sleep disordered breathing, as well as CPAP requirement and compliance with CPAP...
October 6, 2016: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/27707442/nasal-dilator-strip-is-an-effective-placebo-intervention-for-severe-obstructive-sleep-apnea
#14
Fabiana Yagihara, Geraldo Lorenzi-Filho, Rogerio Santos-Silva
STUDY OBJECTIVES: The aim of this study was to evaluate the effects of nasal dilator strip (NDS) as a placebo intervention compared with continuous positive airway pressure (CPAP) treatment in patients with severe obstructive sleep apnea (OSA). METHODS: Patients were treated with both NDS and nasal CPAP. The sequence was randomized and interposed by 15 days of washout. Polysomnography was performed at baseline and on the first night of intervention with NDS and CPAP (titration)...
September 29, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27692134/efficacy-of-nasal-continuous-positive-airway-pressure-on-patients-with-osa-with-erectile-dysfunction-and-low-sex-hormone-levels
#15
Zhijun Li, Tingyu Tang, Wenjuan Wu, Liang Gu, Jianzong Du, Tian Zhao, Xiaoxi Zhou, Haiyan Wu, Guangyue Qin
PURPOSE: This study aimed to test the hypothesis that erectile dysfunction (ED) is common in men with obstructive sleep apnea (OSA). We also assessed the efficacy of continuous positive airway pressure (CPAP) treatment for ED and sex hormone levels in patients with severe OSA and ED. METHODS: A total of 153 OSA patients and 60 healthy controls were enrolled in this study. The International Index of Erectile Dysfunction-5 (IIEF-5) score was obtained, and blood samples were collected for analysis of sex hormones after polysomnography...
October 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27665460/effect-of-continuous-positive-airway-pressure-cpap-therapy-on-il-23-in-patients-with-obstructive-sleep-apnea
#16
Murat Can, Fırat Uygur, Hakan Tanrıverdi, Bilgehan Acıkgoz, Barıs Alper, Berrak Guven
Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder characterized by repeated episodes of apnea and hypopnea during sleep. Continuous positive airway pressure (CPAP) is the most effective method for treating OSAS and alleviating the patients' symptoms. The aim of this study was to assess the effect of 3-month CPAP therapy on serum levels of IL-23 in patients with OSAS. Twenty-three patients with newly diagnosed moderate-to-severe OSAS who had not yet started nasal CPAP treatment were prospectively enrolled...
September 24, 2016: Immunologic Research
https://www.readbyqxmd.com/read/27648308/impact-of-a-new-nasal-pillows-mask-on-patients-acceptance-compliance-and-willingness-to-remain-on-cpap-therapy
#17
Alison Wimms, Sahisha Ketheeswaran, Claus Ziegenbein, Laura Jennings, Holger Woehrle
Aim. Continuous positive airway pressure (CPAP) masks are a key factor in patient compliance. This program assessed the performance of a new nasal pillows mask (NPM) on a variety of new and established obstructive sleep apnea (OSA) patients using CPAP therapy. Methods. Five programs were developed to assess the new NPM [AirFit P10, ResMed] on naïve patients; patients established on another NPM; patients using a nasal mask; patients with low CPAP compliance; and patients who wished to stop using CPAP therapy...
2016: Sleep Disorders
https://www.readbyqxmd.com/read/27641366/temporal-trends-in-inpatient-pediatric-sleep-apnea-surgery-1993-through-2010
#18
David F Smith, Ting Sa, Matthew Fenchel, Aliza P Cohen, Christine Heubi, Sally R Shott, Christine G Gourin, Stacey L Ishman
OBJECTIVES/HYPOTHESIS: We sought to characterize changes in the patterns of inpatient surgical sleep care over time and ascertain if these changes were consistent with previously reported trends in adult surgical sleep care. STUDY DESIGN: Repeated cross-sectional study. METHODS: Discharge data from the U.S. Nationwide Inpatient Sample for 125,691 nasal, palatal, or hypopharyngeal procedures in children for sleep-disordered breathing or obstructive sleep apnea (OSA) from 1993 to 2010 were analyzed using cross-tabulations and multivariate regression modeling...
September 19, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27638725/factors-predicting-cpap-adherence-in-obstructive-sleep-apnea-syndrome
#19
Moussa Riachy, Samer Najem, Mirella Iskandar, Jad Choucair, Ihab Ibrahim, Georges Juvelikian
PURPOSE: Obstructive sleep apnea (OSA) is associated with a range of neurocognitive and cardiovascular complications, leading to a compromised quality of life. Continuous positive airway pressure (CPAP) is the gold standard therapeutic intervention for this disorder, yet patient compliance remains essential to its success. This study aimed at identifying the determinants of short-term and long-term CPAP adherence in a group of Lebanese patients. METHODS: This cross-sectional study, conducted at the Sleep Center of Hôtel-Dieu de France hospital in Lebanon, included patients diagnosed with OSA and treated with CPAP for at least one night between June 2008 and January 2015...
September 16, 2016: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/27626150/evaluation-of-posterior-ocular-changes-using-enhanced-depth-imaging-optical-coherence-tomography-in-patients-with-obstructive-sleep-apnea-syndrome
#20
İsa Yuvacı, Emine Pangal, Nurettin Bayram, Sevgi Arık Yüksel, Bedirhan Alabay, Alperen Ağadayı, Ender Sırakaya, Ahmet Gülhan
PURPOSE: Evaluation of the nerve fiber thicknesses of the macula, choroid, and retina using the apnea-hypopnea index in individuals with obstructive sleep apnea syndrome (OSAS) without systemic components. METHODS: Prospective, controlled study. The central macular, choroidal, and retinal nerve fiber layer (RNFL) thicknesses were evaluated using enhanced depth imaging-spectral domain optical coherence tomography in individuals with OSAS. In people with severe OSAS who had received treatment, posterior ocular structures were examined over 3 months (4th and 12th weeks), and changes were evaluated...
July 2016: Arquivos Brasileiros de Oftalmologia
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