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Pamela Louise M Tolentino, Ate Poortinga, Hideki Kanamaru, Saskia Keesstra, Jerry Maroulis, Carlos Primo C David, Coen J Ritsema
The Philippines is one of the most vulnerable countries in the world to the potential impacts of climate change. To fully understand these potential impacts, especially on future hydrological regimes and water resources (2010-2050), 24 river basins located in the major agricultural provinces throughout the Philippines were assessed. Calibrated using existing historical interpolated climate data, the STREAM model was used to assess future river flows derived from three global climate models (BCM2, CNCM3 and MPEH5) under two plausible scenarios (A1B and A2) and then compared with baseline scenarios (20th century)...
2016: PloS One
Maria Bernadete Galrão de Almeida Figueiredo, Vanessa Rocha de Santana, Maria Júlia Nardelli, Matheus de Souza Nogueira, Danilo Xavier Azevedo, Danillo Primo Andrade Santana, Ana Galrão de Almeida Figueiredo, Ívison Xavier Duarte, Ricardo Luiz Cavalcanti de Albuquerque, Sônia Oliveira Lima
PURPOSE: To assess the effect of aqueous extract of Peumus Boldus (AEPB) on the liver proliferative response after parcial hepatectomy of 70% (PH) in rodents. METHODS: Twenty Wistar rats were divided in two groups: AEPB100 (whose rats received 100mg/Kg of AEPB, once a day, orally, in 4 days prior to the first surgical procedure) and Vehicle (whose rats were treated similarly with distilled water). Both groups underwent PH. After 24 hours the remaining livers were removed for studying the proliferation of hepatocytes by Ki-67 and 2mL of blood were collected for serological assessment: cholesterol, glucose, triglycerides, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and total, direct and indirect bilirubin...
September 2016: Acta Cirúrgica Brasileira
Cinzia Niolu, Emanuela Bianciardi, Giorgio Di Lorenzo, Sara Nicolai, Monica Celi, Michele Ribolsi, Adalgisa Pietropolli, Carlo Ticconi, Umberto Tarantino, Alberto Siracusano
RIASSUNTO. Introduzione. La depressione maggiore (MD) e l'osteoporosi sono malattie ad alta prevalenza nel genere femminile, associate a morbosità e mortalità. Sebbene alcuni studi abbiano dimostrato un'associazione tra MD, ridotta densità minerale ossea (BMD) e osteoporosi, non sono stati chiariti i meccanismi causali. Lo stile di attaccamento insicuro è stato messo in relazione con la patogenesi e il decorso di malattie croniche come la MD e le malattie cardiovascolari. Obiettivo di questo studio pilota è esplorare la relazione tra MD e BMD...
July 2016: Rivista di Psichiatria
S Hraiech, J Bordes, J L Mège, X de Lamballerie, R Charrel, Y Bechah, B Pastorino, C Guervilly, J M Forel, M Adda, J M Rolain, H Lepidi, D Raoult, S Lehingue, L Papazian
OBJECTIVES: Cytomegalovirus (CMV) reactivation in intensive care unit patients may increase mortality and favour bacterial pneumonia. We developed a murine model to compare the severity of staphylococcal pneumonia after CMV reactivation and in CMV-negative mice. METHODS: Balb/c mice were primo-infected with murine cytomegalovirus (MCMV n=90) or received saline (control n=90). After latency, all mice underwent caecal ligation and puncture to trigger MCMV reactivation in MCMV primary-infected mice...
October 5, 2016: Clinical Microbiology and Infection
Tae-Rin Kwon, Eun Ja Choi, Chang Taek Oh, Dong-Ho Bak, Song-I Im, Eun Jung Ko, Hyuck Ki Hong, Yeon Shik Choi, Joon Seok, Sun Young Choi, Gun Young Ahn, Beom Joon Kim
BACKGROUND AND OBJECTIVES: Many studies have investigated the application of micro-insulated needles with radio frequency (RF) to treat acne in humans; however, the use of a micro-insulated needle RF applicator has not yet been studied in an animal model. The purpose of this study was to evaluate the effectiveness of a micro-insulated needle RF applicator in a rabbit ear acne (REA) model. STUDY DESIGN/MATERIALS AND METHODS: In this study, we investigated the effect of selectively destroying the sebaceous glands using a micro-insulated needle RF applicator on the formation of comedones induced by application of 50% oleic acid and intradermal injection of P...
September 29, 2016: Lasers in Surgery and Medicine
Alessandro Bertuccio, Chiara Robba, Giannantonio Spena, Pietro Primo Versari
INTRODUCTION: Dural arteriovenous fistulas (DAVFs) is a challenging condition in vascular neurosurgery. Development of new endovascular techniques has progressively modified treatment strategies; however, surgery is still considered a valid option of treatment of this pathology. MATERIALS AND METHODS: From a retrospective analysis of our database, we selected 107 patients who underwent surgical treatment for DAVFs. Patients were grouped into five categories according to the Borden and Cognard classifications...
2016: Acta Neurochirurgica. Supplement
Leonardo Pereira Franch, Camila F Amantino, Maryanne T Melo, Ana Paula de Lima Montaldi, Fernando L Primo, Antonio Claudio Tedesco
BACKGROUND: The photodynamic therapy (PDT) has been used to treat cancer mainly by inducing oxidative stress. Our aim was to evaluate the effect of PDT and its combination with methoxyamine (MX), a blocker of base excision repair (BER), in cells expressing high levels of the APE1 protein, which is involved in cell oxidative damage response. METHODS: The HeLa and A549 cells were treated for 3h with chloroaluminum phthalocyanine incorporated into a well-designed nanoemulsion (ClAlPc/NE); and then irradiated by visible light (@670nm) with doses of 0...
September 6, 2016: Photodiagnosis and Photodynamic Therapy
Raquel Ferreira, João Primo, Luís Adão, Anabela Gonzaga, Helena Gonçalves, Rui Santos, Paulo Fonseca, José Santos, Vasco Gama
Cardiac surgery for structural heart disease (often involving the left atrium) and radiofrequency catheter ablation of atrial fibrillation have led to an increased incidence of regular atrial tachycardias, often presenting as atypical flutters. This type of flutter is particularly common after pulmonary vein isolation, especially after extensive atrial ablation including linear lesions and/or defragmentation. The authors describe the case of a 51-year-old man, with no relevant medical history, referred for a cardiology consultation in 2009 for paroxysmal atrial fibrillation...
October 2016: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
Jonathan W Riess, Primo N Lara, David R Gandara
No abstract text is available yet for this article.
September 6, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Dania Comparcini, Marco Tomietto, Valentina Simonetti, Francesca Zambri, Giancarlo Cicolini
AIM: To explore the first year midwifery students' clinical learning experience and satisfaction; to analyse the association between students' satisfaction and individual motivation. METHOD: The multicentre cross-sectional study was carried out in four Italian midwifery degree courses. A convenience sample of 61 students filled out the Italian version of the "Clinical Learning Environment and Supervision plus Nurse Teacher (CLES+T) scale" after the conclusion of their first clinical placement...
April 2016: Professioni Infermieristiche
D A de Luis, O Izaola, B de la Fuente, D Primo, R Aller
BACKGROUND: The main genetic variant described in NPY gene is rs16147 (G-399A) and it is located within the promoter region upstream of the gene for neropeptide Y (NPY). We evaluate the effects of the rs16147 NPY gene polymorphism on metabolic changes secondary to weight loss after 3 months of a hypocaloric diet in adult obese patients. METHODS: A population of 82 obese patients was analysed in an interventional design of one arm. Before and after 3 months on a hypocaloric diet, an anthropometric evaluation, an assessment of nutritional intake and a biochemical analysis were performed...
September 7, 2016: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
M Ruiz, A Quiñones, M R Martínez-Cuenca, P Aleza, R Morillon, L Navarro, E Primo-Millo, B Martínez-Alcántara
Tetraploid citrus seedlings are more tolerant to salt stress than diploid genotypes. To provide insight into the causes of differences in salt tolerance due to ploidy and thus to better understand Cl(-) exclusion mechanisms in citrus, diploid and tetraploid seedlings of Carrizo citrange (CC) were grown at 0 (control) and 40mM NaCl (salt-treated) medium for 20 days. Chloride uptake and root-to-shoot translocation rates were on average 1.4-fold higher in diploid than in tetraploid salt-treated plants, which resulted in a greater (1...
August 21, 2016: Journal of Plant Physiology
David A Clunie, Don K Dennison, Dawn Cram, Kenneth R Persons, Mark D Bronkalla, Henri Rik Primo
This white paper explores the technical challenges and solutions for acquiring (capturing) and managing enterprise images, particularly those involving visible light applications. The types of acquisition devices used for various general-purpose photography and specialized applications including dermatology, endoscopy, and anatomic pathology are reviewed. The formats and standards used, and the associated metadata requirements and communication protocols for transfer and workflow are considered. Particular emphasis is placed on the importance of metadata capture in both order- and encounter-based workflow...
October 2016: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Jacopo Giuliani, Andrea Bonetti
Riassunto. Lo scopo di questo studio è quello di valutare i costi dei farmaci (con particolare riferimento alle terapie con farmaci biologici) utilizzati nella terapia di conversione in una popolazione non selezionata di pazienti affetti da carcinoma del colon-retto in stadio avanzato, al fine di ottenere una resezione epatica R0. In questa rassegna sono stati selezionati i report completi e gli aggiornamenti di tutti gli studi clinici randomizzati (di fase II e fase III) che confrontassero almeno 2 regimi di terapia con farmaci biologici in prima linea in pazienti affetti da carcinoma del colon-retto in stadio avanzato di malattia...
August 2016: Recenti Progressi in Medicina
Daniel Antonio de Luis, Olatz Izaola, David Primo, David Pacheco
BACKGROUND: The effect of the rs10767664 variant of the brain-derived neurotrophic factor gene on weight loss after bariatric surgery has not been evaluated. We decided to investigate the role of the rs10767664 variant on outcomes after biliopancreatic diversion surgery. MATERIALS AND METHODS: A sample of 90 patients with morbid obesity without diabetes mellitus was operated. Biochemical and anthropometric evaluation were realized at basal visit and at each visit during 3 years (at 1, 2 and 3 years)...
August 20, 2016: Journal of Nutrigenetics and Nutrigenomics
Chae Jeong Lim, So Yeong Lee, Pan Dong Ryu
Recently, we identified the primo-vascular system (PVS), a novel vascular network, in rat subcutaneous tissues. Little is known about the subcutaneous PVS (sc-PVS). Here, we examined the ultrastructure of the sc-PVS in the hypodermis at the rat abdominal midline by electron microscopy. On the surface of sc-PVS, we observed three types of cells: microcells (5-6 μm), large elliptical cells (>20 μm), and erythrocyte (3-4 μm). The inside of the sc-PVS was filled with numerous cells, which can be classified into three major groups: leucocytes, mast cells, and erythrocytes...
2016: Advances in Experimental Medicine and Biology
Jungdae Kim, Dong-Hyun Kim, Sharon Jiyoon Jung, Kwang-Sup Soh
This study aims to investigate the temporal change of a vascular system now known as the primo vascular system (PVS). We used Alcian blue (AB) dye for imaging the distribution of the PVS in lymphatic vessels. The target lymph vessels were chosen as they are easily accessible from the skin, and long-term observation is possible with intact physiological conditions due to a minimal surgical procedure. AB solution was injected into the inguinal lymph node and the target lymph vessels were located along the superficial epigastric vessels...
2016: Advances in Experimental Medicine and Biology
Kyung A Kang
In 1962, Bonghan Kim in North Korea published a report on a new vascular system in mammals, which he claimed as the acupuncture meridian. He soon named it the Bonghan System. Between 1962 and 1965, he published five reports, with detailed descriptions on the system. Kim also described the self-regenerating nature of a unique cell type Sanals in the system and these cells are now confirmed to be a type of stem cells. According to his findings, the system appears to have vital roles in maintaining mammalian lives...
2016: Advances in Experimental Medicine and Biology
Mariaelena D'Ambrosio, Juan C Molinero, Ulisses M Azeiteiro, Miguel A Pardal, Ana L Primo, Daniel Nyitrai, Sónia C Marques
The persistent massive blooms of gelatinous zooplankton recorded during recent decades may be indicative of marine ecosystem changes. In this study, we investigated the potential influence of the North Atlantic climate (NAO) variability on decadal abundance changes of gelatinous carnivore zooplankton in the Mondego estuary, Portugal, over the period 2003-2013. During the 11-year study, the community of gelatinous carnivores encompassed a larger diversity of hydromedusae than siphonophores; the former dominated by Obelia spp...
September 2016: Marine Environmental Research
Marlene Anastassova Kristeva
The origin of the wide spread node and duct system described by Rai et al. remains a mystery. The explanation came when another study on yolk sack hemopoiesis was compared with the "primo vascular system". It came out that the yolk sack hematogenic tissue, introduced to the embryo by the vitelline veins, does not disappear in adults, but continues to exist in form of nods and ducts along blood vessels and different organs.
September 1, 2016: Stem Cells and Development
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