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Dario Muti, Barbara Carpita, Elisa Diadema, Gabriele Massimetti, Luciano Conti, Claudia Carmassi, Liliana Dell'Osso
RIASSUNTO. Scopo. La maggior parte della ricerca storiografica sulla psichiatria agli inizi del ventesimo secolo prende principalmente in considerazione l'istituzione manicomiale. Per indagare le caratteristiche di internamento in una popolazione clinica, abbiamo analizzato i registri clinici, recentemente resi disponibili, della Clinica di Malattie Nervose e Mentali dell'Università di Pisa, prendendo in considerazione tutte le ammissioni dal 24 aprile 1907 al 31 gennaio 1913. Metodo. Sono stati raccolti dati demografici e clinici di 1068 pazienti, effettuando test del Chi Quadrato per elicitare la correlazione fra trasferimento manicomiale e differenza di genere; inoltre sono stati effettuati T-Test per confrontare la media di età, la media di giorni di ospedalizzazione e la media di ricoveri successivi nei pazienti trasferiti in manicomio e in quelli licenziati...
March 2018: Rivista di Psichiatria
Momir Polenakovic, Nada Pop-Jordanova, Zoran Gucev
Papers on medical subjects have been published since the first issue of the journal Prilozi in 1969, totalling a number of of 957 (nine hundred and fifty seven) papers have been published in Prilozi. Two hundred and twenty nine cover subjects on natural sciences and mathematics, and 728 (seven hundred and twenty eight) subjects on medical sciences. So far, 2017 No. XXXVIII-2, 622 (six hundred and twenty two) papers published in Prilozi are in Pubmed. Prilozi is published three times a year and it is covered by the following services: Baidu Scholar, Case, Celdes, CNKI Scholar (China National Knowledge Infrastructure), CNPIEC, DOAJ (Directory of Open Access Journals), EBSCO (relevant databases), EBSCO Discovery Service, Elsevier - SCOPUS, Google Scholar, J-Gate, JournalTOCs, KESLI-NDSL (Korean National Discovery for Science Leaders), Naviga (Softweco), Primo Central (ExLibris), Publons, PubMed, ReadCube, ResearchGate, SCImago (SJR), Summon (Serials Solutions/ProQuest), TDNet, Ulrich's Periodicals Directory/ulrichsweb WanFang Data, WorldCat (OCLC)...
December 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
Salvador Oliver-Ferrando, Joaquim Segalés, Sergio López-Soria, Antonio Callén, Olivier Merdy, François Joisel, Marina Sibila
BACKGROUND: This study sought to evaluate the effect of sow vaccination against Porcine circovirus 2 (PCV2) on reproductive parameters during two consecutive reproductive cycles. The study was performed in a PCV2 subclinical infected breeding herd (PCV2 circulation but absence of major reproductive problems). Ninety-four pregnant sows were primo-immunized with a commercial PCV2 vaccine and ninety-seven were injected with phosphate-buffered saline at 6 and 3 weeks before the first studied farrowing, and then boosted at 2 weeks before the second one...
April 16, 2018: BMC Veterinary Research
Jiuai Sun
This paper describes experimental evaluations of an optical scanning device for skin surface recovery using multiple light source photometric stereo method. The portable optical device based on the principle of six-light photometric stereo was developed and subjected to evaluation and advancement through clinical trials for the purpose of monitoring skin conditions. As the device can provide objective topographic data for the description of the skin surface condition, the evaluation processes are mainly applied on skin in vitro and in vivo and compared with a commercial product, PRIMOS, which has been so far considered as a standard device used for skin surface measurement...
January 2018: Journal of Cosmetic Science
Jun-Young Shin, Jong-Ok Ji, Da-Woon Choi, Sang-Heon Choi, Jong-Gu Choi, Min-Suk Rho, Ji Yoon Lee, Sang-Suk Lee
It is known that the existence of primo vascular system (PVS) including the primo nodes and vessels. However, it is poorly understood the relevant genes in the PVS system both patho- and physiologic condition. Here, we first examined the gene expression in primo vessels (PV) floating in lymphatic endothelium by isolation of PVS and lymphatic vessels (LV) containing PVS. To investigate therapeutic effects, both PV and LV containing PVS were isolated after lipopolysaccharides (LPS) injection and acupuncture electric stimulation (AES) at two acupoints of Joksamni (ST36) and Hapgok (LI04) following LPS...
April 4, 2018: Journal of Acupuncture and Meridian Studies
Pui Yan Ho, Zhijian Duan, Neelu Batra, Joseph L Jilek, Mei-Juan Tu, Jing-Xin Qiu, Zihua Hu, Theodore Wun, Primo N Lara, Ralph W DeVere White, Hong-Wu Chen, Ai-Ming Yu
Noncoding RNAs (ncRNAs) produced in live cells may better reflect intracellular ncRNAs for research and therapy. Attempts were made to produce biological ncRNAs, but at low yield or success rate. Here we first report a new ncRNA bioengineering technology, using more stable ncRNA carrier (nCAR) containing a pre-miR-34a derivative identified by rational design and experimental validation. This approach offered a remarkable higher-level expression (40-80% of total RNAs) of recombinant ncRNAs in bacteria, and gave an 80% success rate (33 out of 42 ncRNAs)...
March 30, 2018: Journal of Pharmacology and Experimental Therapeutics
Nicolas Breysse, Gaelle Vial, Lauriane Pattingre, Bernadette C Ossendorp, Karin Mahieu, Hermine Reich, Anton Rietveld, Christian Sieke, Trijntje van der Velde-Koerts, Xavier Sarda
Proposals to update the methodology for the international estimated short-term intake (IESTI) equations were made during an international workshop held in Geneva in 2015. Changes to several parameters of the current four IESTI equations (cases 1, 2a, 2b, and 3) were proposed. In this study, the overall impact of these proposed changes on estimates of short-term exposure was studied using the large portion data available in the European Food Safety Authority PRIMo model and the residue data submitted in the framework of the European Maximum Residue Levels (MRL) review under Article 12 of Regulation (EC) No 396/2005...
June 3, 2018: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
Renata Prandini Adum de Matos, Marilia Freitas Calmon, Camila Fernanda Amantino, Luisa Lina Villa, Fernando Lucas Primo, Antonio Claudio Tedesco, Paula Rahal
Cervical cancer is the fourth cause of cancer death in women. Curcumin has antineoplastic properties. Furthermore, curcumin may be used as a photosensitizing agent in Photodynamic Therapy. This study aimed to investigate the effects of Photodynamic Therapy in cellular viability using curcumin-nanoemulsion as a photosensitizing drug in cervical carcinoma cell lines. The empty nanoemulsion presented very low cytotoxicity in all cell lines analyzed. Additionally, the incubation with curcumin-nanoemulsion at 20  μ M of curcumin showed more than 80% of cell viability for cell lines...
2018: BioMed Research International
Vicente Navarro-Llopis, Jaime Primo, Sandra Vacas
Improved trap efficacy is crucial for implementing control methods for red palm weevil, Rhynchophorus ferrugineus (Olivier; Coleoptera: Dryophthoridae), based on trapping systems, such as mass trapping, attract and infect or attract and sterilize techniques. Although new trap designs have been proposed and aggregation pheromone dispensers have been optimized, aspects such as the use of co-attractants (molasses) and trap placement are still not well defined and standardized. The efficacy of three concentrations of molasses and different formulations to reduce water evaporation in traps was studied in different field trials to improve trapping systems and to prolong trap servicing periods...
March 20, 2018: Journal of Economic Entomology
Roberto D'Amato, Maurizio Petrelli, Primo Proietti, Andrea Onofri, Luca Regni, Diego Perugini, Daniela Businelli
BACKGROUND: Biofortification of food crops has been used to increase the intake of Se in the human diet, even though this may change the concentration of other elements and modify the nutritional properties of the enriched food. Therefore, Se-biofortification programs should include the routine assessment of the overall mineral composition of enriched plants. RESULTS: Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA ICP-MS) was used for the assessment of mineral composition of table olives...
March 25, 2018: Journal of the Science of Food and Agriculture
G Kang, T N T Tu, S Kim, H Yang, M Jang, D Jo, J Rye, J Baek, H Jung
OBJECTIVE: Although dissolving microneedle patches have been widely studied in the cosmetics field, no comparisons have been drawn with the topical applications available for routine use. In this study, two wrinkle-improving products, adenosine-loaded dissolving microneedle patches and an adenosine cream, were evaluated for efficacy, with respect to skin wrinkling, dermal density, elasticity, and hydration, and safety in a clinical test on the crow's feet area. METHODS: Clinical efficacy and safety tests were performed for 10 weeks on 22 female subjects with wrinkles around their eyes...
March 25, 2018: International Journal of Cosmetic Science
Lanlin Yang, Sufen Cai, Shuoping Zhang, Xiangyi Kong, Yifan Gu, Changfu Lu, Jing Dai, Fei Gong, Guangxiu Lu, Ge Lin
STUDY QUESTION: Does single cleavage-stage (Day 3) embryo transfer using a time-lapse (TL) hierarchical classification model achieve comparable ongoing pregnancy rates (OPR) to single blastocyst (Day 5) transfer by conventional morphological (CM) selection? SUMMARY ANSWER: Day 3 single embryo transfer (SET) with a hierarchical classification model had a significantly lower OPR compared with Day 5 SET with CM selection. WHAT IS KNOWN ALREADY: Cleavage-stage SET is an alternative to blastocyst SET...
March 13, 2018: Human Reproduction
Bruno Tochetto Primo, Leonardo Marcos Mezzari, Luís Carlos da Fontoura Frasca, Raquel Linderman, Elken Gomes Rivaldo
PURPOSE: To evaluate and compare the clinical and radiographic outcomes of mandibular rehabilitation with fixed prostheses on three implants with immediate versus delayed loading. MATERIALS AND METHODS: The sample comprised 21 patients who underwent treatment with immediate loading and 23 who received delayed loading. All had worn their prostheses for at least 18 months. Radiographic evaluation of bone loss was carried out in Adobe Photoshop CS5 by a single calibrated examiner using digitized panoramic radiographs...
March 15, 2018: International Journal of Oral & Maxillofacial Implants
Luana Leal Roberto, Daniele Durães Noronha, Taiane Oliveira Souza, Ellen Janayne Primo Miranda, Andréa Maria Eleutério de Barros Lima Martins, Alfredo Maurício Batista De Paula, Efigênia Ferreira E Ferreira, Desirée Sant'ana Haikal
This study sought to investigate factors associated with the lack of access to information on oral health among adults. It is a cross-sectional study, carried out among 831 adults (35-44 years of age). The dependent variable was access to information on how to avoid oral problems, and the independent variables were gathered into subgroups according to the theoretical model for literacy in health. Binary logistic regression was carried out, and results were corrected by the design effect. It was observed that 37...
March 2018: Ciência & Saúde Coletiva
Amanda Sapp, José C Huguet-Tapia, Maximiliano Sánchez-Lamas, Giuliano T Antelo, Emiliano D Primo, Jimena Rinaldi, Sebastián Klinke, Fernando A Goldbaum, Hernán R Bonomi, Brent C Christner, Lisandro H Otero
Here, we report the draft genome sequence of Methylobacterium sp. strain V23, a bacterium isolated from accretion ice of the subglacial Lake Vostok (3,592 meters below the surface). This genome makes possible the study of ancient and psychrophilic genes and proteins from a subglacial environment isolated from the surface for at least 15 million years.
March 8, 2018: Genome Announcements
Céline Deblanc, Séverine Hervé, Stéphane Gorin, Charlie Cador, Mathieu Andraud, Stéphane Quéguiner, Nicolas Barbier, Frédéric Paboeuf, Nicolas Rose, Gaëlle Simon
Maternally-derived antibodies (MDA) reduce piglet susceptibility to swine influenza A virus, but interfere with post-infectious immune responses, raising questions about protection after waning of passive immunity. We therefore analysed the impact of different levels of residual MDA on virus excretion and immune responses in piglets born to vaccinated sows (MDA+) and infected with H1N1 at 5, 7 or 11 weeks of age, in comparison to piglets born to unvaccinated sows (MDA-). Subsequent protection against a second homologous infection occurring 4 weeks after the primo-infection was also investigated...
March 2018: Veterinary Microbiology
D A de Luis, D Primo, O Izaola, R Aller
BACKGROUND: The role of CB2R gene variants on weight loss after a dietary intervention remained unclear. OBJECTIVE: Our aim was to analyze the effects of rs3123554 of CB2R receptor gene on metabolic and adiposity parameters after two different hypocaloric diets in obese subjects DESIGN: A Caucasian population of 280 obese patients was enrolled. Patients were randomly allocated during 3 months to one of two diets (Diet I - moderate in carbohydrate. Vs Diet II -normal in carbohydrate)...
March 5, 2018: Diabetes Research and Clinical Practice
Lucas Primo de Carvalho Alves, Neusa Sica da Rocha
OBJECTIVES: Melancholic depression is a type of depression which is closely related to biological variables than are other types of depression. Its clinical features can be assessed using six items on the Hamilton Depression Rating Scale (HAM-D6 ). Previous studies have shown, using item response theory, that the symptom depressed mood is the least severe melancholic feature; work and activities, somatic symptoms and psychic anxiety are of moderate severity; and feelings of guilt and psychomotor retardation are the most severe...
March 8, 2018: Bipolar Disorders
Karl Stefic, Sophie Novelli, Nadia Mahjoub, Remonie Seng, Jean-Michel Molina, Christine Cheneau, Francis Barin, Marie-Laure Chaix, Laurence Meyer, Constance Delaugerre
We assessed the impact of early antiretroviral treatment (ART) on HIV antibody detection by rapid tests in 44 individuals after several years of successful ART. HIV self-tests and point-of-care tests were negative in respectively 30% and 7-9% of cases. These data reinforce the message that patients should never be retested after entering HIV care.
March 2, 2018: Journal of Infectious Diseases
Jacqueline Gayet-Primo, Daniel B Yaeger, Roupen A Khanjian, Teresa Puthussery
Silent voltage-gated potassium channel subunits (KV S) interact selectively with members of the KV 2 channel family to modify their functional properties. The localization and functional roles of these silent subunits remain poorly understood. Mutations in the KV S subunit, KV 8.2 ( KCNV2 ), lead to severe visual impairment in humans, but the basis of these deficits remain unclear. Here, we examined the localization, native interactions and functional properties of KV 8.2-containing channels in mouse, macaque and human photoreceptors of either sex...
February 24, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
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