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https://www.readbyqxmd.com/read/29684313/breathing-and-coding-a-bit-easier-changes-to-international-classification-of-disease-coding-for-pulmonary-hypertension
#1
REVIEW
Stephen C Mathai, Sherin Mathew
International Classification of Disease (ICD) coding system is broadly utilized by healthcare providers, hospitals, healthcare payers, and governments to track health trends and statistics at the global, national, and local levels and to provide a reimbursement framework for medical care based upon diagnosis and severity of illness. The current iteration of the ICD system, ICD-10, was implemented in 2015. While many changes to the prior ICD-9 system were included in the ICD-10 system, the newer revision failed to adequately reflect advances in the clinical classification of certain diseases such as pulmonary hypertension (PH)...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29683908/clinical-updates-in-women-s-health-care-summary-asthma
#2
Jennifer A Namazy, Michael Schatz, Mitchell Dombrowski
Asthma is a common and potentially life-threatening lung disease. The prevalence of asthma is higher in women than in men. This monograph provides an overview of the pathophysiology, evaluation, and management of asthma in women. Management approaches in reproductive-aged, pregnant, and postmenopausal patients are addressed.
May 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29683474/antidepressants-for-the-treatment-of-depression-in-people-with-cancer
#3
REVIEW
Giovanni Ostuzzi, Faith Matcham, Sarah Dauchy, Corrado Barbui, Matthew Hotopf
BACKGROUND: Major depression and other depressive conditions are common in people with cancer. These conditions are not easily detectable in clinical practice, due to the overlap between medical and psychiatric symptoms, as described by diagnostic manuals such as the Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Classification of Diseases (ICD). Moreover, it is particularly challenging to distinguish between pathological and normal reactions to such a severe illness...
April 23, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29683305/maternity-care-update-preconception-care
#4
Andrew Smith, Wendy B Barr, Erin Bassett-Novoa, Nicholas LeFevre
Family physicians are in a unique position to ensure that women receive preconception care. The Centers for Disease Control and Prevention, the American College of Obstetricians and Gynecologists, and the American Academy of Family Physicians recommend preconception care for all women, but particularly for women with comorbid conditions such as obesity, diabetes, and chronic hypertension. Family physicians should ask all women of reproductive age who are at risk of unintended pregnancy if they desire pregnancy within the next year and, based on this answer, provide counseling on contraception or preconception care...
April 2018: FP Essentials
https://www.readbyqxmd.com/read/29683293/psoriasis-as-a-cardiovascular-risk-factor-updates-and-algorithmic-approach
#5
Emanuele Cozzani, Gianmarco Rosa, Martina Burlando, Aurora Parodi
Although psoriasis is predominantly a chronic inflammatory skin disorder, it has been known to be associated with cardiovascular disease. Patients with psoriasis, particularly with moderate to severe forms, present an increased rate of cardiovascular mortality, myocardial infarction and stroke. However the pathophysiology of the relationship between psoriasis and cardiovascular risk and comorbidities has not yet completely known. Chronic inflammation may be considered a solid link between psoriasis and related cardiovascular events...
April 19, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29682375/myeloid-sarcoma-after-allogenic-stem-cell-transplantation-for-acute-myeloid-leukemia-successful-consolidation-treatment-approaches-in-two-patients
#6
Silje Johansen, Hilde Kollsete Gjelberg, Aymen Bushra Ahmed, Øystein Bruserud, Håkon Reikvam
Myeloid sarcoma is an extramedullary (EM) manifestation (i.e., manifestation outside the bone marrow) of acute myeloid leukemia (AML); it is assumed to be relatively uncommon and can be the only manifestation of leukemia relapse after allogenic stem cell transplantation (allo-SCT). An EM sarcoma can manifest in any part of the body, although preferentially manifesting in immunological sanctuary sites as a single or multiple tumors. The development of myeloid sarcoma after allo-SCT is associated with certain cytogenetic abnormalities, developing of graft versus host disease (GVHD), and treatment with donor lymphocytes infusion (DLI)...
2018: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/29682309/australasian-society-for-hiv-viral-hepatitis-and-sexual-health-medicine-hiv-pre-exposure-prophylaxis-clinical-guidelines-update-april-2018
#7
EDITORIAL
Edwina Wright, Andrew Grulich, Katy Roy, Mark Boyd, Vincent Cornelisse, Darren Russell, Darryl O'Donnell, Bill Whittaker, Levinia Crooks, Iryna Zablotska
Daily use of coformulated tenofovir and emtricitabine for HIV pre-exposure prophylaxis (PrEP) by populations at high risk of HIV infection is now recommended in guidelines from the United States, Europe and Australia and globally through the 2015 WHO guidelines. These 2017 Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine's (ASHM) PrEP Guidelines are an updated adaptation of the 2014 US Centers for Disease Control's PrEP guidelines and are designed to: •Support the prescription of PrEP using forms of coformulated tenofovir and emtricitabine that have been registered in Australia by the Therapeutic Goods Administration and other bioequivalent generic drugs that are available in Australia through self-importation, private prescription or Australian PrEP clinical trials•Assist clinicians in the evaluation of patients who are seeking PrEP•Assist clinicians in commencing and monitoring patients on PrEP including PrEP dosing schedules, management of side-effects and toxicity, use of PrEP in pregnancy and in chronic hepatitis B infection and how to cease PrEP Daily PrEP with co-formulated tenofovir and emtricitabine, used continuously or for shorter periods of time, is recommended in these guidelines as a key HIV-prevention option for men who have sex with men (MSM), transgender men and women, heterosexual men and women, and people who inject drugs (PWID) at substantial risk of HIV acquisition...
April 1, 2018: Journal of Virus Eradication
https://www.readbyqxmd.com/read/29681236/an-industry-update-what-is-the-latest-news-in-the-therapeutic-delivery-field
#8
Catarina Pinto Reis
The present industry update covers the period 1-31 December 2017. Information was sourced primarily from scientific literature and various news websites, company press releases, regulatory and patent agencies. The most representative (not all) examples of research are herein described and they are mainly focused on metabolic diseases, cancer, blood pressure diseases, eyes diseases and, in some cases, in rare diseases. In this paper, there was a clear positive approval tendency for several companies where they offered novel therapeutic delivery candidates...
May 2018: Therapeutic Delivery
https://www.readbyqxmd.com/read/29681202/quality-of-life-in-psoriatic-arthritis
#9
Tania Gudu, Laure Gossec
Psoriatic arthritis (PsA) is a multi-organ chronic inflammatory disease which impacts patients both physically and psychologically. The highest priority for patients goes to pain relief, but also to ability to function and participate in social life, fatigue, and psychological distress. Areas covered: In the present article, we will review current knowledge on impairments of health-related quality of life related to PsA, as well as patient priorities and patient-reported outcome measures such as the PsA Impact of Disease or the PsA Quality of Life questionnaires...
April 23, 2018: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/29680985/egg-consumption-and-the-risk-of-cardiovascular-disease-and-all-cause-mortality-guangzhou-biobank-cohort-study-and-meta-analyses
#10
Lin Xu, Tai Hing Lam, Chao Qiang Jiang, Wei Sen Zhang, Feng Zhu, Ya Li Jin, Jean Woo, Kar Keung Cheng, G Neil Thomas
PURPOSE: Eggs are highly nutritious but concerns over their cholesterol content have led to dietary avoidance among many. There are also important international differences in relevant dietary guidance. We conducted the first prospective study in China investigating the association of egg consumption, cardiovascular disease (CVD) mortality, and a meta-analysis. METHODS: We included 28,024 participants without CVD at baseline (2003-8) in Guangzhou Biobank Cohort Study...
April 21, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29680441/the-impact-of-surgery-on-survival-after-progression-of-glioblastoma-a-retrospective-cohort-analysis-of-a-contemporary-patient-population
#11
REVIEW
Rahul A Sastry, Ganesh M Shankar, Elizabeth R Gerstner, William T Curry
Despite updated management of glioblastoma (GB), progression is virtually inevitable. Previous data suggest a survival benefit from resection at progression; however, relatively few studies have evaluated the role of surgery in the context of contemporary GB treatment and widespread use of bevacizumab and chemotherapy. As such, the purpose of this study is to evaluate outcomes following surgical resection in patients with progressive GB since 2008. The records of all patients who underwent biopsy or resection of GB between January 1, 2008, and December 31, 2015, were retrospectively reviewed to identify 368 patients with progressive GB...
April 18, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29680338/a-comparison-of-the-updated-diamond-forrester-cad-consortium-and-confirm-history-based-risk-scores-for-predicting-obstructive-coronary-artery-disease-in-patients-with-stable-chest-pain-the-scot-heart-coronary-cta-cohort
#12
Lohendran Baskaran, Ibrahim Danad, Heidi Gransar, Bríain Ó Hartaigh, Joshua Schulman-Marcus, Fay Y Lin, Jessica M Peña, Amanda Hunter, David E Newby, Philip D Adamson, James K Min
OBJECTIVES: This study sought to compare the performance of history-based risk scores in predicting obstructive coronary artery disease (CAD) among patients with stable chest pain from the SCOT-HEART study. BACKGROUND: Risk scores for estimating pre-test probability of CAD are derived from referral-based populations with a high prevalence of disease. The generalizability of these scores to lower prevalence populations in the initial patient encounter for chest pain is uncertain...
April 13, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29679644/non-viral-based-mir-delivery-and-recent-developments
#13
REVIEW
Annalise Elizabeth Labatut, George Mattheolabakis
miRNAs are promising therapeutic targets or tools for the treatment of numerous diseases, with most prominently, cancer. The inherent capacity of these short nucleic acids to regulate multiple cancer-related pathways simultaneously has prompted strong research on understanding miR functions and their potential use for therapeutic purposes. A key determinant of miR therapeutics' potential for treatment is their delivery. Viral and non-viral vectors attempt to address the major limitations associated with miR delivery, but several hurdles have been identified...
April 18, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29679500/a-unified-material-decomposition-framework-for-quantitative-dual-and-triple-energy-ct-imaging
#14
Wei Zhao, Don Vernekohl, Fei Han, Bin Han, Hao Peng, Yong Yang, Lei Xing, James K Min
PURPOSE: Many clinical applications depend critically on the accurate differentiation and classi-fication of different types of materials in patient anatomy. This work introduces a unified framework for accurate nonlinear material decomposition and applies it, for the first time, in the concept of triple-energy CT (TECT) for enhanced material differentiation and classification as well as dual-energy CT METHODS: We express polychromatic projection into a linear combination of line integrals of material-selective images...
April 21, 2018: Medical Physics
https://www.readbyqxmd.com/read/29679391/cardiovascular-effects-of-sitagliptin-an-anti-diabetes-medicine
#15
REVIEW
Yi Zhou, Zhiying Guo, Wenjing Yan, Wen Wang
Dipeptidyl-peptidase-4 (DPP-4) inhibitors, as the most recent available anti-diabetic agents, were generally used in clinical treatment of type 2 diabetes (T2DM). In addition to anti-diabetic effects, the five most widely used DPP-4 inhibitors (sitagliptin, vildagliptin, saxagliptin, linagliptin and alogliptin) also exert cardiovascular protective effects. In recent years, increasing studies suggest that sitagliptin shows pleiotropic impacts towards the cardiovascular system either with or without diabetes...
April 21, 2018: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29679099/radiation-induced-carotid-artery-lesions
#16
REVIEW
Verónica Fernández-Alvarez, Fernando López, Carlos Suárez, Primoz Strojan, Avraham Eisbruch, Carl E Silver, William M Mendenhall, Johannes A Langendijk, Alessandra Rinaldo, Anne W M Lee, Jonathan J Beitler, Robert Smee, Javier Alvarez, Alfio Ferlito
PURPOSE: To review the current aspects of knowledge related to the risk of cerebrovascular events in patients receiving head and neck radiotherapy. METHODS: A literature search was performed in PubMed. Papers meeting selection criteria were reviewed. RESULTS: We provide an update on the problem by identifying key studies that have contributed to our current understanding of the epidemiology, radiologic features, pathogenesis, and treatment of the disease...
April 20, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29678945/ers-ecdc-statement-european-union-standards-for-tuberculosis-care-2017-update
#17
G B Migliori, G Sotgiu, S Rosales-Klintz, R Centis, L D'Ambrosio, I Abubakar, G Bothamley, J A Caminero, D M Cirillo, M Dara, G de Vries, S Aliberti, A T Dinh-Xuan, R Duarte, F Midulla, I Solovic, D Subotic, M Amicosante, A M Correira, A Cirule, G Gualano, H Kunst, F Palmieri, V Riekstina, S Tiberi, R Verduin, M J van der Werf
The International Standards for Tuberculosis (TB) Care define the essential level of care for managing patients who have or are presumed to have TB, or are at increased risk of developing the disease. The resources and capacity in the European Union and the European Economic Area (EU/EEA) permit higher standards of care to secure quality and timely TB diagnosis, prevention and treatment. On this basis, the European Union Standards for Tuberculosis Care (ESTC) were published in 2012 as standards specifically tailored to the EU-setting...
April 20, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29678022/using-rdf-and-git-to-realize-a-collaborative-metadata-repository
#18
Mark R Stöhr, Raphael W Majeed, Andreas Günther
The German Center for Lung Research (DZL) is a research network with the aim of researching respiratory diseases. The participating study sites' register data differs in terms of software and coding system as well as data field coverage. To perform meaningful consortium-wide queries through one single interface, a uniform conceptual structure is required covering the DZL common data elements. No single existing terminology includes all our concepts. Potential candidates such as LOINC and SNOMED only cover specific subject areas or are not granular enough for our needs...
2018: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/29677308/vitamin-d-calcium-or-combined-supplementation-for-the-primary-prevention-of-fractures-in-community-dwelling-adults-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#19
Leila C Kahwati, Rachel Palmieri Weber, Huiling Pan, Margaret Gourlay, Erin LeBlanc, Manny Coker-Schwimmer, Meera Viswanathan
Importance: Osteoporotic fractures result in significant morbidity and mortality. Objective: To update the evidence for benefits and harms of vitamin D, calcium, or combined supplementation for the primary prevention of fractures in community-dwelling adults to inform the US Preventive Services Task Force. Data Sources: PubMed, EMBASE, Cochrane Library, and trial registries through March 21, 2017; references; and experts. Surveillance continued through February 28, 2018...
April 17, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29677050/changes-in-albuminuria-and-renal-outcome-in-patients-with-type-2-diabetes-and-hypertension-a-real-life-observational-study
#20
Francesca Viazzi, Antonio Ceriello, Paola Fioretto, Carlo Giorda, Pietro Guida, Giuseppina Russo, Eulalia Greco, Salvatore De Cosmo, Roberto Pontremoli
OBJECTIVES: To assess the predictive role of changes in albuminuria on the loss of renal function under antihypertensive treatment in patients with type 2 diabetes (T2D). METHODS: Clinical records from a total of 12 611 patients with hypertension and T2D, attending 100 antidiabetic centers in Italy, with normal estimated glomerular filtration rate (eGFR) at baseline and regular visits during a 4-year period were retrieved and analyzed. We assessed the association between changes in albuminuria status during a 1-year baseline period and time updated blood pressure (BP) and eGFR loss over the subsequent 4-year follow-up...
April 19, 2018: Journal of Hypertension
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