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https://www.readbyqxmd.com/read/29900177/reporting-data-analysis-methods-in-high-impact-respiratory-journals
#1
Pentti Nieminen, Tuula Toljamo, Hannu Vähänikkilä
Data analysis methods play an important role in respiratory research. We evaluated the application and complexity of data analytical methods in high-impact respiratory journals and compared the statistical reporting in these respiratory articles with reports published in other eminent medical journals. This study involved a total of 160 papers published in 2015 in the European Respiratory Journal, American Journal of Respiratory and Critical Care Medicine, Chest and Thorax , and 680 papers published between 2007-2015 in other medical journals including the Lancet and New England Journal of Medicine ...
April 2018: ERJ Open Research
https://www.readbyqxmd.com/read/29859937/the-mental-health-act-review-getting-out-of-the-twilight-zone
#2
EDITORIAL
The Lancet Psychiatry
No abstract text is available yet for this article.
May 30, 2018: Lancet Psychiatry
https://www.readbyqxmd.com/read/29698540/the-impact-of-clinical-trial-units-on-the-value-of-clinical-research-in-switzerland
#3
Belinda von Niederhäusern, Annette Magnin, Christiane Pauli-Magnus
A prominent 2014 series by The Lancet on "Increasing value, reducing waste in biomedical research" provided recommendations on how to optimise precious resources, including in clinical research. Despite being ideally placed to lead the movement in patient-oriented clinical research, academia struggles to take corresponding measures and find ways to evaluate their impact. A decade ago, Swiss stakeholders established constructive initiatives to improve the quality of clinical research, including a national Clinical Trial Unit (CTU) Network, predominantly rooted in university hospitals...
April 26, 2018: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29696304/the-perceived-effectiveness-of-traditional-and-faith-healing-in-the-treatment-of-mental-illness-a-systematic-review-of-qualitative-studies
#4
REVIEW
A S J van der Watt, T van de Water, G Nortje, B D Oladeji, S Seedat, O Gureje
PURPOSE: This work complements a quantitative review by Nortje et al. (Lancet Psychiatry 3(2):154-170, 2016) by exploring the qualitative literature in regard to the perceived effectiveness of traditional and faith healing of mental disorders. METHOD: Qualitative studies focusing specifically on traditional and/or faith healing practices for mental illness were retrieved from eight databases. Data were extracted  into basic coding sheets to facilitate the assessment of the quality of eligible papers using the COREQ...
April 25, 2018: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29689357/red-meat-and-colon-cancer-a-review-of-mechanistic-evidence-for-heme-in-the-context-of-risk-assessment-methodology
#5
REVIEW
Claire Kruger, Yuting Zhou
On October 26, 2015, IARC published a summary of their findings regarding the association of cancer with consumption of red meat or processed meat (IARC 2015a; The Lancet Oncology 2015). The Working Group concluded that there is limited evidence in human beings for carcinogenicity from the consumption of red meat and inadequate evidence in experimental animals for the carcinogenicity of consumption of red meat. Nevertheless, the working group concluded that there is strong mechanistic evidence by which ingestion of red meat can be linked to human colorectal cancer and assigned red meat to Group 2A "probably carcinogenic to humans"...
April 21, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29671204/nafld-and-hiv-do-sex-race-and-ethnicity-explain-hiv-related-risk
#6
REVIEW
Subada Soti, Kathleen E Corey, Jordan E Lake, Kristine M Erlandson
PURPOSE OF REVIEW: Here, we review the epidemiology, diagnosis, and management of non-alcoholic fatty liver disease (NAFLD) in the general population, discuss HIV-specific differences in NAFLD pathogenesis, and summarize what is known regarding differences in NAFLD by race/ethnicity and sex. RECENT FINDINGS: The reported prevalence of NAFLD among people living with HIV varies by age, body mass index, comorbidity, and method of NAFLD diagnosis, but is generally thought to be greater among HIV-infected compared to HIV-uninfected populations...
April 18, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29605206/the-100-most-influential-publications-in-asthma-from-1960-to-2017-a-bibliometric-analysis
#7
REVIEW
Yulan Qu, Chen Zhang, Zhenli Hu, Sha Li, Chen Kong, Yunye Ning, Yan Shang, Chong Bai
BACKGROUND: The area of asthma medicine has produced a large volume of important clinical and scientific papers that can be found in those most influential journals. The purpose of our study was to identify the 100 most cited papers in asthma research and to analyze their characteristics. METHODS: We used the Institute for Scientific Information Web of Knowledge Database to identify the most frequently cited articles published from 1960 to December 2017. Original articles and reviews were included in the study...
April 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29603853/a-comprehensive-review-of-guidelines-on-prevention-of-preterm-birth-albeit-lacking-in-consensus-in-clinical-recommendations
#8
L Al-Hafez, S P Chauhan
No abstract text is available yet for this article.
March 31, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29566938/reducing-waste-in-pediatric-clinical-research
#9
Behrouz Kassai, Faustine Glais, Guillaume Grenet, Catherine Cornu, Kim-An Nguyen
The importance of reducing waste and increasing value when conducting research has been emphasized by a series of articles published in the Lancet in 2014. A survey indicates that, one year later, these articles have not influenced how research is conducted. In this review, we explore four stages described by Moher et al. in research production that lead to waste. We show that all four stages including, questions relevant to users, appropriate design conduct and analysis, accessible full research, unbiased and usable reports, efficient research regulation and management of biomedical research are also producing an important waste in pediatric research...
April 2018: Thérapie
https://www.readbyqxmd.com/read/29553422/publication-patterns-on-occupied-palestine-in-four-key-medical-journals-1990-2016-a-descriptive-study
#10
Mads Gilbert
BACKGROUND: The atrocities in Syria have been covered in the four general medical weekly journals in the USA and the UK. Medical journal articles addressing political determinants of public health have rightly described and criticised the international community's failure to enforce humanitarian law while urging global bodies of power to ensure protection of civilians and civilian infrastructure and medical services. Discussions of the political influences on health of people in the occupied Palestinian territory (West Bank and Gaza Strip) seem to be considered politically out-of-bounds by some medical journals...
February 21, 2018: Lancet
https://www.readbyqxmd.com/read/29496500/update-in-outpatient-general-internal-medicine-practice-changing-evidence-published-in-2017
#11
REVIEW
Mark L Wieland, Jason H Szostek, Majken T Wingo, Jason A Post, Karen F Mauck
Clinicians are challenged to identify new practice-changing articles in the medical literature. To identify the practice-changing articles published in 2017 most relevant to outpatient general internal medicine, 5 internists reviewed the following sources: 1) titles and abstracts from internal medicine journals with the 7 highest impact factors, including New England Journal of Medicine, Lancet, Journal of the American Medical Association, British Medical Journal, Public Library of Science Medicine, Annals of Internal Medicine, and JAMA Internal Medicine; 2) synopses and syntheses of individual studies, including collections in the American College of Physicians Journal Club, Journal Watch, and Evidence-Based Medicine; 3) databases of synthesis, including Evidence Updates and the Cochrane Library...
February 26, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29485559/innovate-global-plastic-and-reconstructive-surgery-cleft-lip-and-palate-charity-database
#12
Pinkal S Patel, Karen Y Chung, Leila Kasrai
BACKGROUND: There is an emerging interest in global surgery. The Lancet Commission on Global Surgery recognizes the important role that nongovernmental organizations (NGOs) play in the delivery of cleft lip and/or palate (CLP) surgical care. To better address the unmet burden of surgical disease, the commissioners propose the use of a centralized registry to maximize coordination of global surgical volunteerism efforts. This study aims to create a comprehensive database of CLP organizations...
February 26, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29480409/the-global-spine-care-initiative-a-summary-of-the-global-burden-of-low-back-and-neck-pain-studies
#13
REVIEW
Eric L Hurwitz, Kristi Randhawa, Hainan Yu, Pierre Côté, Scott Haldeman
PURPOSE: This article summarizes relevant findings related to low back and neck pain from the Global Burden of Disease (GBD) reports for the purpose of informing the Global Spine Care Initiative. METHODS: We reviewed and summarized back and neck pain burden data from two studies that were published in Lancet in 2016, namely: "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015" and "Global, regional, and national disability-adjusted life years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015...
February 26, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29470822/the-concept-of-the-ccn-protein-family-revisited-a-centralized-coordination-network
#14
REVIEW
Bernard Perbal
The wide array of biological properties attributed to the CCN family of proteins (Perbal in Lancet 363(9402):62-64, 2004) led me to reconsider the possible relationship and roles that these proteins may play as a team, instead of acting on their own as individual regulators in various signaling pathways. The dynamic model which I present in this review stems from the contribution of the biological properties that we established for CCN3, one of the three founding members of the CCN family, which was identified by our group as the first CCN protein showing growth inhibitory properties (1992), expressed mainly in quiescent cells (1996), and showing anti-tumor activities in several cellular models both ex vivo and in vivo...
March 2018: Journal of Cell Communication and Signaling
https://www.readbyqxmd.com/read/29463308/reproducibility-of-clinical-research-in-critical-care-a-scoping-review
#15
Daniel J Niven, T Jared McCormick, Sharon E Straus, Brenda R Hemmelgarn, Lianne Jeffs, Tavish R M Barnes, Henry T Stelfox
BACKGROUND: The ability to reproduce experiments is a defining principle of science. Reproducibility of clinical research has received relatively little scientific attention. However, it is important as it may inform clinical practice, research agendas, and the design of future studies. METHODS: We used scoping review methods to examine reproducibility within a cohort of randomized trials examining clinical critical care research and published in the top general medical and critical care journals...
February 21, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29434521/nursing-education-challenges-and-solutions-in-sub-saharan-africa-an-integrative-review
#16
Thokozani Bvumbwe, Ntombifikile Mtshali
Background: The Lancet Commission and the Global Health Workforce Alliance reported that professional education has generally not kept up the pace of health care challenges. Sub Saharan Africa needs an effective and efficient nursing education system to build an adequate, competent and relevant nursing workforce necessary for the achievement of Sustainable Development Goals. The Plan of Action for Scaling up Quality Nursing and Midwifery Education and Practice for the African Region 2012 - 2022 provided a framework for scale up of nurses and midwives...
2018: BMC Nursing
https://www.readbyqxmd.com/read/29432862/responsible-epidemiologic-research-practice-a-guideline-developed-by-a-working-group-of-the-netherlands-epidemiological-society
#17
Gerard M H Swaen, Miranda Langendam, Joost Weyler, Huibert Burger, Sabine Siesling, Willem Jan Atsma, Lex Bouter
OBJECTIVES: To develop a guideline on Responsible Epidemiologic Research Practice that will increase value and transparency, increase the accountability of the epidemiologists, and reduce research waste. SETTING: A working group of the Netherland Epidemiological Society was given the task of developing a guideline that would meet these objectives. Several publications about the need to prevent Detrimental Research Practices triggered this work. Among these were a series in the Lancet on research waste and a subsequent series on transparency in the Journal of Clinical Epidemiology...
February 10, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29412437/an-international-position-statement-on-the-management-of-frailty-in-diabetes-mellitus-summary-of-recommendations-2017
#18
REVIEW
A J Sinclair, A Abdelhafiz, T Dunning, M Izquierdo, L Rodriguez Manas, I Bourdel-Marchasson, J E Morley, M Munshi, J Woo, B Vellas
AIM: The International Position Statement provides the opportunity to summarise all existing clinical trial and best practice evidence for older people with frailty and diabetes. It is the first document of its kind and is intended to support clinical decisions that will enhance safety in management and promote high quality care. METHODS: The Review Group sought evidence from a wide range of studies that provide sufficient confidence (in the absence of grading) for the basis of each recommendation...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29378418/cpx-351-changing-the-landscape-of-treatment-for-patients-with-secondary-acute-myeloid-leukemia
#19
Chetasi Talati, Jeffrey E Lancet
Multiple novel therapeutic agents against acute myeloid leukemia (AML) have been evaluated in the past several decades without meaningful clinical improvement in outcomes, especially for AML patients age ≥60, where the overall incidence of AML is highest. Therapeutic options mainly consist of hypomethylating agents, ongoing clinical trials and, less commonly, intensive cytotoxic chemotherapy. CPX-351, a novel liposomal formulation which encapsulates cytarabine and daunorubicin in 5:1 molar ratio, has shown promising efficacy, leading to recent US FDA approval for front-line therapy for patients with therapy-related AML and AML with myelodysplasia-related changes based on a large multicenter Phase III clinical trial...
January 30, 2018: Future Oncology
https://www.readbyqxmd.com/read/29368021/access-to-safe-timely-and-affordable-surgical-care-in-uganda-a-stratified-randomized-evaluation-of-nationwide-public-sector-surgical-capacity-and-core-surgical-indicators
#20
Katherine Albutt, Maria Punchak, Peter Kayima, Didacus B Namanya, Geoffrey A Anderson, Mark G Shrime
BACKGROUND: Access to safe surgery is critical to health, welfare, and economic development. In 2015, the Lancet Commission on Global Surgery recommended that all countries collect surgical indicators to lend insight into improving surgical care. No nationwide high-quality data exist for these metrics in Uganda. METHODS: A standardized quantitative hospital assessment and a semi-structured interview were administered to key stakeholders at 17 randomly selected public hospitals...
January 24, 2018: World Journal of Surgery
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