keyword
MENU ▼
Read by QxMD icon Read
search

human bocavirus

keyword
https://www.readbyqxmd.com/read/29155041/epidemiological-and-clinical-characteristics-of-coronavirus-and-bocavirus-respiratory-infections-after-allogeneic-stem-cell-transplantation-a-prospective-single-center-study
#1
José Luis Piñana, Silvia Madrid, Ariadna Pérez, Juan Carlos Hernández-Boluda, Estela Giménez, María José Terol, Marisa Calabuig, David Navarro, Carlos Solano
Epidemiological data about coronaviruses (CoVs) and human bocavirus (HBoV) in the setting of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is scarce. METHODS: We conducted a prospective longitudinal study on respiratory viral infections (RVIs) in allo-HSCT recipients having respiratory symptoms from December 2013 until June 2016. Respiratory virus in upper and/or lower respiratory tract (URT and LRT) specimens were tested using Luminex xTAG RVP Fast v1 assay. RESULTS: Seventy-nine consecutive allo-HSCT recipients developed a total of 192 virologically documented RVI episodes over 30 months...
November 15, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29028159/serologically-diagnosed-acute-human-bocavirus-1-infection-in-childhood-community-acquired-pneumonia
#2
Amanda C Nascimento-Carvalho, Ana-Luisa Vilas-Boas, Maria-Socorro H Fontoura, Man Xu, Tytti Vuorinen, Maria Söderlund-Venermo, Olli Ruuskanen, Cristiana M Nascimento-Carvalho
AIM: To assess the role of human bocavirus 1 (HBoV1) as a causative agent of non-severe community-acquired pneumonia (CAP) in children. METHODS: Patients aged 2-59 months with non-severe CAP (respiratory complaints and radiographic pulmonary infiltrate/consolidation) attending a University Hospital in Salvador, Brazil were enrolled in a prospective cohort. From 820 recruited children in a clinical trial (ClinicalTrials.gov NCT01200706), nasopharyngeal aspirate (NPA), and acute and convalescent serum samples were obtained from 759 (92...
October 13, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29021400/human-parvovirus-infection-of-human-airway-epithelia-induces-pyroptotic-cell-death-via-inhibiting-apoptosis
#3
Xuefeng Deng, Wei Zou, Min Xiong, Zekun Wang, John F Engelhardt, Shui Qing Ye, Ziying Yan, Jianming Qiu
Human bocavirus 1 (HBoV1) is a human parvovirus that causes acute respiratory tract infections in young children. In this study, we confirmed that, when polarized/well-differentiated human airway epithelia are infected with HBoV1 in vitro, they develop damage characterized by barrier function disruption and cell hypotrophy. Cell death mechanism analyses indicated that the infection induced pyroptotic cell death characterized by caspase-1 activation. Unlike infections with other parvoviruses, HBoV1 infection did not activate the apoptotic or necroptotic cell death pathway...
October 11, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28934425/human-bocavirus-capsid-messenger-rna-detection-in-children-with-pneumonia
#4
MULTICENTER STUDY
Robert Schlaberg, Krow Ampofo, Keith D Tardif, Chris Stockmann, Keith E Simmon, Weston Hymas, Steven Flygare, Brett Kennedy, Anne Blaschke, Karen Eilbeck, Mark Yandell, Jon A McCullers, Derek J Williams, Kathryn Edwards, Sandra R Arnold, Anna Bramley, Seema Jain, Andrew T Pavia
Background: The role of human bocavirus (HBoV) in respiratory illness is uncertain. HBoV genomic DNA is frequently detected in both ill and healthy children. We hypothesized that spliced viral capsid messenger RNA (mRNA) produced during active replication might be a better marker for acute infection. Methods: As part of the Etiology of Pneumonia in the Community (EPIC) study, children aged <18 years who were hospitalized with community-acquired pneumonia (CAP) and children asymptomatic at the time of elective outpatient surgery (controls) were enrolled...
September 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28922613/the-etiology-of-community-acquired-pneumonia-among-children-under-5%C3%A2-years-of-age-in-mainland-china-2001-2015-a-systematic-review
#5
Guijun Ning, Xuxia Wang, Dan Wu, Zundong Yin, Yixing Li, Huaqing Wang, Weizhong Yang
BACKGROUND: The aim of this systematic review was to examine the etiology of community-acquired pneumonia (CAP) among Chinese children younger than 5 y and provide evidence for further cost-effectiveness analyses for vaccine development, diagnostic strategies and empirical treatments. METHODS: The literature review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Data were obtained by searching PubMed, Embase, Web-of Science, and the Chinese databases Wanfang Data and China National Knowledge Infrastructure...
November 2, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28910409/risk-of-acute-gastroenteritis-associated-with-human-bocavirus-infection-in-children-a-systematic-review-and-meta-analysis
#6
REVIEW
Ri De, Liying Liu, Yuan Qian, Runan Zhu, Jie Deng, Fang Wang, Yu Sun, Huijin Dong, Liping Jia, Linqing Zhao
Human bocaviruses (HBoVs), which were first identified in 2005 and are composed of genotypes 1-4, have been increasingly detected worldwide in pediatric patients with acute gastroenteritis. To investigate if HBoV infection is a risk factor of acute gastroenteritis in children younger than 5 years old, we searched PubMed, Embase (via Ovid), the Chinese Biomedical Literature Database (CBM), and the Cochrane Library for studies assessing the prevalence of HBoVs in individuals from Oct 25, 2005 to Oct 31, 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28883450/virome-analysis-for-identification-of-novel-mammalian-viruses-in-bats-from-southeast-china
#7
Dan Hu, Changqiang Zhu, Yi Wang, Lele Ai, Lu Yang, Fuqiang Ye, Chenxi Ding, Jiafeng Chen, Biao He, Jin Zhu, Hui Qian, Wenrong Xu, Youjun Feng, Weilong Tan, Changjun Wang
Bats have been shown as important mammal resevoirs to carry a variety of zoonotic pathogens. To analyze pathogenic species in bats from southeast coastal regions of China, we performed metagenomic sequencing technology for high throughput sequencing of six sentinels from southeast coastal area of China. We obtained 5,990,261 high quality reads from intestine and lung tissue of 235 bats, including 2,975,371 assembled sequences. 631,490 reads predicted overlapping sequences for the open reading frame (ORF), which accounts for 2...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28876460/viral-etiology-of-sporadic-cases-of-parotitis-among-children-in-korea-during-2013-2014
#8
Hae J Kang, Sun H Kim, Jae K Chung, Soon W Lee, Seung B Choi, Hye E Eom, Ok Park, Kisoon Kim, Sung S Kim
Recent years have seen a high incidence of mumps, which is generally diagnosed based on clinical features, especially parotitis, without laboratory confirmation in Korea. To better understand the epidemiology of mumps in Korean children, we investigated sporadic suspected mumps cases with parotitis. In total, 237 buccal swabs or throat swabs collected from children with parotitis who had been clinically diagnosed with mumps were tested using real-time PCR for the detection of six viruses (Epstein-Barr virus, Human herpesvirus 6, Mumps virus, Human parainfluenza virus-1, -2, -3, Human adenovirus, Human bocavirus)...
September 6, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28796554/adeno-associated-virus-human-bocavirus-1-chimeric-vectors-ferreting-out-their-role-in-airway-gene-therapy
#9
Terence R Flotte
No abstract text is available yet for this article.
August 2017: Human Gene Therapy
https://www.readbyqxmd.com/read/28777951/human-bocavirus-1-infection-of-caco-2-cell-line-cultures
#10
Lucía María Ghietto, Ana Paola Toigo D'Angelo, Franco Agustin Viale, María Pilar Adamo
Human bocavirus 1 (HBoV1) is a parvovirus associated with pneumonia in infants. It has been detected in different tissues, including colorectal tumors. In this study, we investigated whether Caco-2 cell line, derived from human colon cancer, can be utilized as a model for HBoV1 replication. We demonstrate HBoV1 replication in Caco-2 cultures supplemented with DEAE-dextran after inoculation with respiratory material from infected patients presenting with acute respiratory infection. A viral cycle of rapid development is displayed...
October 2017: Virology
https://www.readbyqxmd.com/read/28763071/prevalence-of-respiratory-viruses-in-wheezing-children-not-older-than-24-months-of-age
#11
Martín Bedolla-Barajas, Hilda Montero, Jaime Morales-Romero, Adriana Landa-Cardeña, Jahaziel Díaz, Netzahualpilli Delgado-Figueroa, Luis Gustavo Orozco-Alatorre
INTRODUCTION: Wheezing in children not older than 24 months of age is a frequent event, and viruses are usually the causative agents. The aim of the study was to estimate the prevalence of respiratory viruses in wheezing children who were not older than 24 months of age and who had no history of asthma. METHODS: Fifty-five Mexican children were included in an analytical cross-sectional study. Nasal secretions were obtained by using sterile rayon-tipped applicators to identify the virus by polymerase chain reaction or reverse transcription-polymerase chain reaction: adenovirus, bocavirus, human rhinovirus, influenza virus type A, human metapneumovirus, parainfluenza, rhinovirus, and respiratory syncytial virus...
May 2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28731923/human-bocavirus-can-it-trigger-hemophagocytic-lymphohistiocytosis
#12
Sevgen Tanir Basaranoglu, Kubra Aykac, Yasemin Ozsurekci, Inci Bajin, Betul Tavil, Fatma Gumruk, Mehmet Ceyhan
With improvements in molecular diagnostic methods, report of Human bocavirus (HBoV) as an etiologic agent in many studies on viral respiratory and gastrointestinal infections has been increasing. Two pediatric patients who presented with secondary hemophagocytic lymphohistiocytosis were examined for etiologic causes, including viruses. Whole bacterial and fungal cultures and viral serological studies were negative. Viral polymerase chain reaction of nasopharyngeal secretions showed HBoV. One was successfully treated with intravenous immunoglobulins, whereas the other died with multiorgan failure...
November 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28719504/severe-lower-respiratory-tract-infection-caused-by-human-bocavirus-1-in-an-infant
#13
Vesa Eskola, Man Xu, Maria Söderlund-Venermo
We report a case of human bocavirus 1 (HBoV1) bronchiolitis that led to life-threatening respiratory failure in a 9-month-old boy with no other pathogens detected. The virus-specific diagnosis was confirmed with the detection of HBoV1 DNA in respiratory samples and both DNA and IgM and IgG to HBoV1 in serum samples.
November 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28716110/phylogenic-analysis-of-human-bocavirus-detected-in-children-with-acute-respiratory-infection-in-yaounde-cameroon
#14
Sebastien Kenmoe, Marie-Astrid Vernet, Mohamadou Njankouo-Ripa, Véronique Beng Penlap, Astrid Vabret, Richard Njouom
OBJECTIVE: Human Bocavirus (HBoV) was first identified in 2005 and has been shown to be a common cause of respiratory infections and gastroenteritis in children. In a recent study, we found that 10.7% of children with acute respiratory infections (ARI) were infected by HBoV. Genetic characterization of this virus remains unknown in Central Africa, particularly in Cameroon Leeding us to evaluate the molecular characteristics of HBoV strains in Cameroonian children with ARI. RESULTS: Phylogenetic analysis of partial HBoV VP1/2 sequences showed a low level of nucleotide variation and the circulation of HBoV genotype 1 (HBoV-1) only...
July 17, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28708249/the-impact-of-anthropogenic-pressure-on-the-virological-quality-of-water-from-the-tiber-river-italy
#15
G La Rosa, I Sanseverino, S Della Libera, M Iaconelli, V E V Ferrero, A Barra Caracciolo, T Lettieri
The objective of the present study was to assess the occurrence of major waterborne enteric viruses (enterovirus, norovirus, adenovirus, rotavirus, hepatitis A and E virus) along the Tiber River in Italy, in areas affected by different kinds of anthropogenic pressure (agricultural, urban, industrial and pristine). Moreover, in light of the recent abundant detection of human bocavirus in urban wastewater samples in Italy, the occurrence of this virus was also assessed. Virus detection was based on nested PCR followed by sequencing, and on real-time PCR...
October 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28672995/human-bocavirus-induces-apoptosis-and-autophagy-in-human-bronchial-epithelial-cells
#16
You-Ping Deng, Ying-Juan Liu, Zhan-Qiu Yang, Yan-Jun Wang, Bing-Yan He, Pin Liu
Human bocavirus (HBoV) is classified in the Bocavirus genus within the Parvoviridae family, first identified from children with respiratory diseases. Previous studies have investigated the stimulating effect of HBoV on cell apoptosis and autophagy. In the present study, human bronchial epithelial cells (HBECs) were utilized to examine the mechanism of HBoV recombination expressing vector (pWHL-1) on the promotion of cell apoptosis and autophagy. The results from the present study indicated that pWHL-1 inhibited the proliferation of HBECs in a time-dependent manner...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28659483/human-bocavirus-1-is-a-novel-helper-for-adeno-associated-virus-replication
#17
Zekun Wang, Xuefeng Deng, Wei Zou, John F Engelhardt, Ziying Yan, Jianming Qiu
Human bocavirus 1 (HBoV1) is an autonomous parvovirus that infects well-differentiated primary human airway epithelia (HAE) in vitro. In human embryonic kidney (HEK) 293 cells, transfection of a duplex HBoV1 genome initiates viral DNA replication and produces progeny virions that are infectious in HAE. HBoV1 takes advantage of signaling pathways in the DNA damage response for efficient genome amplification in both well-differentiated (non-dividing) HAE and dividing HEK293 cells. On the other hand, adeno-associated virus 2 (AAV2) is a helper-dependent dependoparvovirus, and productive AAV2 replication requires co-infection with a helper virus (e...
June 28, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28657532/-human-bocavirus-1-role-in-the-acute-respiratory-infection-and-epidemiology-in-cordoba-argentina
#18
REVIEW
María Pilar Adamo
Human bocavirus 1 (HBoV1) is an agent of acute respiratory infection frequent in children. It can cause pneumonia in infants, in the absence of epidemiological risk factors and comorbidities. Well-controlled studies of clinical cases and case series are still useful for the characterization of the clinicoepideiological features of the infection, while research dives on the molecular biology of the virus and the virus-cell relationship allowing to unveil tha natural history of the infection. This article reviews the state of the art and future perspectives on this new human parvovirus and its etiological role in the respiratory pathology...
2017: Revista de la Facultad de Ciencias Médicas
https://www.readbyqxmd.com/read/28647513/respiratory-syncytial-virus-bronchiolitis-weather-conditions-and-air-pollution-in-an-italian-urban-area-an-observational-study
#19
Raffaella Nenna, Melania Evangelisti, Antonella Frassanito, Carolina Scagnolari, Alessandra Pierangeli, Guido Antonelli, Ambra Nicolai, Serena Arima, Corrado Moretti, Paola Papoff, Maria Pia Villa, Fabio Midulla
BACKGROUND: In this study we sought to evaluate the association between viral bronchiolitis, weather conditions, and air pollution in an urban area in Italy. METHODS: We included infants hospitalized for acute bronchiolitis from 2004 to 2014. All infants underwent a nasal washing for virus detection. A regional agency network collected meteorological data (mean temperature, relative humidity and wind velocity) and the following air pollutants: sulfur dioxide, nitrogen oxide, carbon monoxide, ozone, benzene and suspended particulate matter measuring less than 10µm (PM10) and less than 2...
October 2017: Environmental Research
https://www.readbyqxmd.com/read/28639594/viral-aetiology-of-wheezing-in-children-under-five
#20
Prithi Sureka Mummidi, Radha Tripathy, Bhagirathi Dwibedi, Amarendra Mahapatra, Suryakanta Baraha
BACKGROUND & OBJECTIVES: Wheezing is a common problem in children under five with acute respiratory infections (ARIs). Viruses are known to be responsible for a considerable proportion of ARIs in children. This study was undertaken to know the viral aetiology of wheezing among the children less than five years of age, admitted to a tertiary care hospital in eastern India. METHODS: Seventy five children, under the age of five years admitted with wheezing, were included in the study...
February 2017: Indian Journal of Medical Research
keyword
keyword
88278
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"