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https://www.readbyqxmd.com/read/20827166/maternal-and-nenonatal-tenofovir-and-emtricitabine-to-prevent-vertical-transmission-of-hiv-1-tolerance-and-resistance
#1
MULTICENTER STUDY
Elise Arrivé, Marie-Laure Chaix, Eric Nerrienet, Stéphane Blanche, Christine Rouzioux, Divine Avit, Leang Sim Kruy, James McIntyre, Leakhena Say, Glenda Gray, Didier K Ekouévi, François Dabis
OBJECTIVE: Viral resistance occurs with a high frequency after single-dose nevirapine. We aimed to evaluate the tolerance and resistance profiles of a combination of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) given to HIV-1-infected delivering women and their newborns. DESIGN: An open-label phase I/II trial in Cambodia, Côte d'Ivoire and South Africa. METHODS: HIV-1-infected pregnant women received zidovudine from the enrollment until the beginning of labor, when single-dose nevirapine and two tablets of TDF/FTC were given...
October 23, 2010: AIDS
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