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Fabio Vescini, Giorgio Borretta, Iacopo Chiodini, Marco Boniardi, Marina Carotti, Elena Castellano, Cristiana Cipriani, Cristina Eller-Vainicher, Sandro Giannini, Maurizio Iacobone, Antonio Stefano Salcuni, Federica Saponaro, Stefano Spiezia, Annibale Versari, Guido Zavatta, Zuzana Mitrova, Rosella Saulle, Simona Vecchi, Debora Antonini, Michele Basile, Alexia Giovanazzi, Agostino Paoletta, Enrico Papini, Agnese Persichetti, Irene Samperi, Alessandro Scoppola, Roberto Novizio, Pietro Giorgio Calò, Filomena Cetani, Luisella Cianferotti, Sabrina Corbetta, Maria Luisa De Rimini, Alberto Falchetti, Giovanni Iannetti, Stefano Laureti, Celestino Pio Lombardi, Bruno Madeo, Claudio Marcocci, Sandro Mazzaferro, Vittorio Miele, Salvatore Minisola, Andrea Palermo, Jessica Pepe, Alfredo Scillitani, Laura Tonzar, Franco Grimaldi, Renato Cozzi, Roberto Attanasio
AIM: This guideline (GL) is aimed at providing a clinical practice reference for the management of sporadic primary hyperparathyroidism (PHPT) in adults. PHPT management in pregnancy was not considered. METHODS: This GL has been developed following the methods described in the Manual of the Italian National Guideline System. For each question, the panel appointed by Associazione Medici Endocrinology (AME) and Società Italiana dell'Osteoporosi, del Metabolismo Minerale e delle Malattie dello Scheletro (SIOMMMS) identified potentially relevant outcomes, which were then rated for their impact on therapeutic choices...
December 23, 2023: Endocrine, Metabolic & Immune Disorders Drug Targets
#22
JOURNAL ARTICLE
Michał Machowski, Aisha Ou-Pokrzewińska, Katarzyna Perzanowska-Brzeszkiewicz, Magdalena Gałecka-Nowak, Szymon Pacho, Mateusz Jermakow, Agnieszka Wójcik, Milena Zoruk, Andrzej Pruszczyk, Karol Deutsch, Marek Roik, Andrzej Łabyk, Piotr Palczewski, Piotr Pruszczyk
BACKGROUND COVID-19 increases the risk of acute cardiovascular diseases (CVDs), including acute coronary syndrome (ACS), acute pulmonary embolism (APE), and acute myocarditis (AMyo). The actual impact of CVDs on mortality of patients with COVID-19 remains unknown. This study aimed to determine whether CVDs influence the course of COVID-19 pneumonia and if they can be easily detected by using common tests and examinations. MATERIAL AND METHODS Data of 249 consecutive patients with COVID-19 hospitalized in a dedicated cardiology department were analyzed...
April 22, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
#23
JOURNAL ARTICLE
Y Liu, X X Zhang, F Q Fang, Y L Xia
With the improvement of oncology diagnosis and treatment, the survival time of cancer patients has been significantly prolonged, and the cancer therapy-related cardiovascular toxicity such as radiotherapy, chemotherapy, immunotherapy, and surgery are becoming more and more prominent, and it is in this context that the germ of Cardio-Oncology exploration has come into being. The multidisciplinary Cardio-Oncology team aims to establish a multidisciplinary prevention and control system to assess patients' baseline risk factors, individualized monitoring, and weighing the risk-benefit ratio of cancer therapy...
April 23, 2024: Zhonghua Yi Xue za Zhi [Chinese medical journal]
#24
JOURNAL ARTICLE
[Short-term efficacy and safety of cardiac contractility modulation in patients with heart failure].
Y K Guo, S Shang, T H Sun, Y Q Fan, Jiasuoer Xiaokereti, Kela TuErhong Zu, X Yang, L Zhang, Y D Li, Y M Lu, J H Zhang, Q Xing, X H Zhou, B P Tang
Objective: To investigate the short-term efficacy and safety of cardiac contractility modulation (CCM) in patients with heart failure. Methods: This was a cross-sectional study of patients with heart failure who underwent CCM placement at the First Affiliated Hospital of Xinjiang Medical University from February to June 2022. With a follow-up of 3 months, CCM sensation, impedance, percent output, and work time were monitored, and patients were compared with pre-and 3-month postoperative left ventricular ejection fraction (LVEF) values, and 6-minute walk test distance and New York Heart Association (NYHA) cardiac function classification, and the occurrence of complications was recorded...
April 24, 2024: Zhonghua Xin Xue Guan Bing za Zhi
#25
JOURNAL ARTICLE
Y Shen, W F Shen
No abstract text is available yet for this article.
April 24, 2024: Zhonghua Xin Xue Guan Bing za Zhi
#26
JOURNAL ARTICLE
Alessandra Corrado, Giuseppe Scidà, Marilena Vitale, Benedetta Caprio, Giuseppina Costabile, Eric Annuzzi, Giuseppe Della Pepa, Roberta Lupoli, Lutgarda Bozzetto
BACKGROUND AND AIMS: Sleep disorders are bidirectionally linked with eating behaviors and glucose metabolism, which could be clinically relevant in type 1 diabetes (T1D). We investigated the relationship between dietary habits and sleep quality in individuals with T1D on insulin pumps and continuous glucose monitoring (CGM). METHODS AND RESULTS: In a cross-sectional study, dietary habits (7-day food diary, EPIC questionnaire) and sleep quality (Pittsburgh Sleep Quality Index questionnaire) were assessed in 59 men and 58 women with T1D, aged 19-79 years, using CGM and insulin pump...
March 8, 2024: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
#27
JOURNAL ARTICLE
Marjorie Richardson, Jean Philippe Bonnet, Capucine Coulon, Olivia Domanski, Benjamin Constans, Max Gonzalez Estevez, Sophie Gautier, Luisa Marsili, Yasmine Ould Hamoud, Augustin Coisne, Hélène Ridon, Anne-Sophie Polge, Stéphanie Mouton, Yasmine Haddad, Francis Juthier, Mouhamed Moussa, Claire Mounier Vehier, Gilles Lemesle, Guillaume Schurtz, Charles Garabedian, Mercedes Jourdain, Sandro Ninni, François Brigadeau, David Montaigne, Nicolas Lamblin, Louise Ghesquiere
BACKGROUND: Cardiovascular diseases (CVDs) are currently the leading cause of maternal death in Western countries. Although multidisciplinary cardio-obstetric teams are recommended to improve the management of pregnant women with CVD, data supporting this approach are scarce. AIMS: To describe the characteristics and outcomes of pregnant patients with CVD managed within the cardio-obstetric programme of a tertiary centre. METHODS: We included every pregnant patient with history of CVD managed by our cardio-obstetric team between June 2017 and December 2019, and collected all major cardiovascular events (death, heart failure, acute coronary syndromes, stroke, endocarditis and aortic dissection) that occurred during pregnancy, peripartum and the following year...
April 12, 2024: Archives of Cardiovascular Diseases
#28
REVIEW
Mohamed J Saadh, Morug Salih Mahdi, Omer Qutaiba B Allela, Tuqa S Alazzawi, Mohammed Ubaid, Nodir M Rakhimov, Zainab H Athab, Pushpamala Ramaiah, Lathamangeswari Chinnasamy, Fahad Alsaikhan, Bagher Farhood
Activation of autophagy, a process of cellular stress response, leads to the breakdown of proteins, organelles, and other parts of the cell in lysosomes, and can be linked to several ailments, such as cancer, neurological diseases, and rare hereditary syndromes. Thus, its regulation is very carefully monitored. Transcriptional and post-translational mechanisms domestically or in whole organisms utilized to control the autophagic activity, have been heavily researched. In modern times, microRNAs (miRNAs) are being considered to have a part in post-translational orchestration of the autophagic activity, with miR-21 as one of the best studied miRNAs, it is often more than expressed in cancer cells...
March 30, 2024: Pathology, Research and Practice
#29
JOURNAL ARTICLE
Optimizing outcomes in men with prostate cancer: the cardiovascular event lowering (CaELo) pathways.
David E Crawford, David Albala, Marc B Garnick, Andrew W Hahn, Paul Maroni, Rana R McKay, Martin Miner, Peter Orio Ⅲ, Kshitij Pandit, Scott Sellinger, Evan Y Yu, Robert H Eckel
INTRODUCTION: Risk of cardiovascular disease is higher among men with prostate cancer than men without, and prostate cancer treatments (especially those that are hormonally based) are associated with increased cardiovascular risk. MATERIALS AND METHODS: An 11-member panel of urologic, medical, and radiation oncologists (along with a men's health specialist and an endocrinologist/preventive cardiologist) met to discuss current practices and challenges in the management of cardiovascular risk in prostate cancer patients who are taking androgen deprivation therapies (ADT) including LHRH analogues, alone and in combination with androgen-targeted therapies (ATTs)...
April 2024: Canadian Journal of Urology
#30
JOURNAL ARTICLE
Daniel Tajdar, Dagmar Lühmann, Laura Walther, Lasse Bittner, Martin Scherer, Ingmar Schäfer
INTRODUCTION: Short-term studies reported improved glycemic control and a decrease in eHbA1c (estimated hemoglobin A1c) in patients with type 1 diabetes during COVID-19 lockdown, but long-term changes are unknown. Therefore, the main objectives are to (1) analyze whether laboratory-measured HbA1c changed during and after two lockdowns and (2) investigate potential variables influencing HbA1c change. METHODS: In this cohort study, 291 adults with type 1 diabetes were followed over 3 years including the prepandemic phase and two lockdowns...
April 20, 2024: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
#31
JOURNAL ARTICLE
Tara J Rick, Smitha Sagaram, Patricia I Jewett, Hee Yun Lee, Karim T Sadak, Lucie M Turcotte, Rachel I Vogel, Anne Blaes
BACKGROUND: Hodgkin lymphoma (HL) survivors who received chest radiotherapy are at risk for breast cancer and cardiovascular disease, but screening adherence is low. We assessed the acceptability/feasibility of a web-based educational intervention and its impact on knowledge of health risks and screening. METHODS: HL survivors were randomized to either an interactive online educational intervention or handouts only. Surveys were completed at baseline and 3 months post-intervention...
April 20, 2024: Journal of Cancer Survivorship: Research and Practice
#32
JOURNAL ARTICLE
Joseph Sartini, Michael Fang, Mary R Rooney, Elizabeth Selvin, Josef Coresh, Scott Zeger
BACKGROUND: Standard continuous glucose monitoring (CGM) metrics: mean glucose, standard deviation, coefficient of variation, and time in range, fail to capture the shape of variability in the CGM time series. This information could facilitate improved diabetes management. METHODS: We analyzed CGM data from 141 adults with type 2 diabetes in the Hyperglycemic Profiles in Obstructive Sleep Apnea (HYPNOS) trial. Participants in HYPNOS wore CGM sensors for up to two weeks at two time points, three months apart...
April 20, 2024: Journal of Diabetes Science and Technology
#33
JOURNAL ARTICLE
Ping-Ting Yang, Li Tang, Sai-Qi Yang, Qiu-Ling Shi, Ya-Qin Wang, Yue-Xiang Qin, Jian-Gang Wang, Ying Li
We aimed to identify different trajectories of remnant cholesterol (RC) and investigate the association of RC trajectories with vascular endothelial function and atherosclerosis progression in a longitudinal cohort of the Chinese population. A total of 521 participants were included in the flow-mediated vasodilation (FMD) subcohort study, and 7775 participants were included in the brachial-ankle pulse wave velocity (baPWV) subcohort study. All participants had ≥ 3 medical examinations during the 10-year follow-up period...
April 19, 2024: Scientific Reports
#34
JOURNAL ARTICLE
Andrew Krumerman, Luigi Di Biase, Edward Gerstenfeld, Timm Dickfeld, Nishant Verma, Leonardo Liberman, Richard Amara, Ardit Kacorri, Lori Crosson, Alan Wilk, Kevin J Ferrick
BACKGROUND: Premature ventricular contractions (PVCs) burden is a risk factor for heart failure and cardiovascular death in patients with structural heart disease. Long-term ECG monitoring can have a significant impact on PVC burden evaluation by further defining PVC distribution patterns. OBJECTIVE: This study aimed to ascertain the optimal duration of ECG monitoring to characterize PVC burden and understand clinical characteristics associated with frequent PVCs and NSVT in a large US cohort...
April 17, 2024: Heart Rhythm: the Official Journal of the Heart Rhythm Society
#35
JOURNAL ARTICLE
Christina Gkolfinopoulou, Angeliki Bourtsala, Daphne Georgiadou, Anastasia-Georgia Dedemadi, Efstratios Stratikos, Angeliki Chroni
Apolipoprotein A-I (apoA-I), the main protein of high-density lipoprotein (HDL), plays a key role in the biogenesis and atheroprotective properties of HDL. We showed previously, that a naturally occurring apoA-I mutation, L178P, induces major defects in protein's structural integrity and functions that may underlie the increased cardiovascular risk observed in carriers of the mutation. Here, a library of marketed drugs (956 compounds) was screened against apoA-I[L178P] to identify molecules that can stabilize the normal conformation of apoA-I...
April 17, 2024: Journal of Lipid Research
#36
JOURNAL ARTICLE
Nicola S Diciolla, Patrícia Rebelo, Guilherme Rodrigues, Ana Sofia Grave, Cíntia Dias, Maria Gomes, E Samuel Santos, Zulmira Pereira, Luísa Pereira, Alda Marques
BACKGROUND: Validating walking trails is essential to promote physical activity (PA) safely and confidently in people with COPD. OBJECTIVES: We aimed to validate predetermined light, moderate, and vigorous intensities of walking trails in people with COPD. METHODS: This cross-sectional study included individuals with COPD walking in predetermined light, moderate and vigorous intensity trails. Activity intensity and volume outcomes were collected...
April 18, 2024: Heart & Lung: the Journal of Critical Care
#37
JOURNAL ARTICLE
Hongyun Shu, Qiaowen Li, Xiaoyong Zhang, Guojun Zhao, Yaqian Cui, Xiyan Zhu
RATIONALE: The novel coronavirus of 2019 (COVID-19) has inflicted significant harm on the cardiovascular system. Patients presenting with fatal chronic arrhythmias after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are rare, arrhythmia caused by SARS-CoV-2 infection need to be taken seriously. PATIENT CONCERNS: Three female patients were admitted to the hospital with syncopal symptoms. Previously, they had been identified to have COVID-19 infection and none of the patients had a preexisting history of arrhythmia, and upon hospital admission, no electrolyte imbalances associated with arrhythmias were observed...
April 19, 2024: Medicine (Baltimore)
#38
JOURNAL ARTICLE
Joris Winters, Michal J Kawczynski, Martijn D Gilbers, Aaron Isaacs, Stef Zeemering, Elham Bidar, Bart Maesen, Michiel Rienstra, Isabelle van Gelder, Sander Verheule, Jos G Maessen, Ulrich Schotten
BACKGROUND: Serum bone morphogenetic protein 10 (BMP10) blood levels are a marker for history of atrial fibrillation (AF) and for major adverse cardiovascular events in patients with AF, including stroke, AF recurrences after catheter ablations, and mortality. The predictive value of BMP10 in patients undergoing cardiac surgery and association with morphologic properties of atrial tissues are unknown. OBJECTIVES: This study sought to study the correlation between BMP10 levels and preoperative clinical traits, occurrence of early and late postoperative atrial fibrillation (POAF), and atrial fibrosis in patients undergoing cardiac surgery...
April 1, 2024: JACC. Clinical Electrophysiology
#39
REVIEW
Gavin Marx, Simon Chowdhury, Laurence Krieger, Elizabeth Hovey, Jeremy Shapiro, Ben Tran, Thean Hsiang Tan, Siobhan Ng, Henry H Woo
Studies of patients with castrate-resistant prostate cancer at high risk of developing overt metastases but with no current evidence of evaluable disease on computed tomography or bone scan non-metastatic castrate-resistant prostrate cancer have demonstrated increased metastasis-free survival and overall survival following treatment with the next-generation oral anti-androgen apalutamide (in addition to therapies that aim to lower testosterone to castrate levels) or luteinizing hormone-releasing hormone antagonist or surgical castration...
April 19, 2024: Asia-Pacific Journal of Clinical Oncology
#40
REVIEW
Devyani Chowdhury, Neha Bansal, Muneera Rasheed, Arwa Saidi, Corey Stiver, Kristin Laraja, Christina Ronai, Carissa Baker Smith, Jonathan N Johnson, Jennifer Co-Vu, Supriya S Jain, Alaina K Kipps, Ritu Sachdeva, Holly Bauser-Heaton, Pei-Ni Jone, Nadine Choueiter, Annette Ansong, Nicole Sutton, Keila N Lopez, Tara Karamlou, Stephanie Fuller, Chris Snyder, Nathaniel W Taggart, Pietro Elliott, Kenneth Shaffer, Roberta Williams
Evidence from medicine and other fields has shown that gender diversity results in better decision making and outcomes. The incoming workforce of congenital heart specialists (especially in pediatric cardiology) appears to be more gender balanced, but past studies have shown many inequities. Gender-associated differences in leadership positions, opportunities presented for academic advancement, and recognition for academic contributions to the field persist. In addition, compensation packages remain disparate if evaluated based on gender with equivalent experience and expertise...
April 19, 2024: Journal of the American Heart Association
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