keyword
https://read.qxmd.com/read/35380031/simpa-an-open-source-toolkit-for-simulation-and-image-processing-for-photonics-and-acoustics
#21
JOURNAL ARTICLE
Janek Gröhl, Kris K Dreher, Melanie Schellenberg, Tom Rix, Niklas Holzwarth, Patricia Vieten, Leonardo Ayala, Sarah E Bohndiek, Alexander Seitel, Lena Maier-Hein
SIGNIFICANCE: Optical and acoustic imaging techniques enable noninvasive visualisation of structural and functional properties of tissue. The quantification of measurements, however, remains challenging due to the inverse problems that must be solved. Emerging data-driven approaches are promising, but they rely heavily on the presence of high-quality simulations across a range of wavelengths due to the lack of ground truth knowledge of tissue acoustical and optical properties in realistic settings...
April 2022: Journal of Biomedical Optics
https://read.qxmd.com/read/34997563/evaluation-of-ultrasonic-scattering-in-agar-based-phantoms-using-3d-printed-scattering-molds
#22
JOURNAL ARTICLE
Antria Filippou, Christakis Damianou
PURPOSE: Acoustic characterization of tissue mimicking materials in terms of attenuation, absorption, scattering and propagation velocity is essential for their utilisation in experiments, thus sparing the need for living tissues or cadavers. Although there is a vast literature regarding the acoustic characterization of such materials in terms of attenuation or propagation velocity, there is limited data regarding the quantification of the scattering coefficient. Herein stimulated the utilisation of four agar-based phantoms featuring different sizes of scattering agar-structures on one of their surfaces so as to provide experimental evaluation of the magnitude of scattering...
January 8, 2022: Journal of Ultrasound
https://read.qxmd.com/read/34888025/a-machine-learning-approach-for-classifying-and-quantifying-acoustic-diversity
#23
JOURNAL ARTICLE
Sara C Keen, Karan J Odom, Michael S Webster, Gregory M Kohn, Timothy F Wright, Marcelo Araya-Salas
1. Assessing diversity of discretely varying behavior is a classical ethological problem. In particular, the challenge of calculating an individuals' or species' vocal repertoire size is often an important step in ecological and behavioral studies, but a reproducible and broadly applicable method for accomplishing this task is not currently available. 2. We offer a generalizable method to automate the calculation and quantification of acoustic diversity using an unsupervised random forest framework. We tested our method using natural and synthetic datasets of known repertoire sizes that exhibit standardized variation in common acoustic features as well as in recording quality...
July 2021: Methods in Ecology and Evolution
https://read.qxmd.com/read/34861122/quantification-of-biomechanical-properties-of-human-corneal-scar-using-acoustic-radiation-force-optical-coherence-elastography
#24
JOURNAL ARTICLE
Xiao Han, Yubao Zhang, Yirui Zhu, Yanzhi Zhao, Hongwei Yang, Guo Liu, Sizhu Ai, Yidi Wang, Chengfeng Xie, Jiulin Shi, Tianyu Zhang, Guofu Huang, Xingdao He
Biomechanical properties of corneal scar are strongly correlated with many corneal diseases and some types of corneal surgery, however, there is no elasticity information available about corneal scar to date. Here, we proposed an acoustic radiation force optical coherence elastography system to evaluate corneal scar elasticity. Elasticity quantification was first conducted on ex vivo rabbit corneas, and the results validate the efficacy of our system. Then, experiments were performed on an ex vivo human scarred cornea, where the structural features, the elastic wave propagations, and the corresponding Young's modulus of both the scarred region and the normal region were achieved and based on this, 2D spatial distribution of Young's modulus of the scarred cornea was depicted...
December 3, 2021: Experimental Biology and Medicine
https://read.qxmd.com/read/34745738/quantitative-and-anatomical-imaging-of-dermal-angiopathy-by-noninvasive-photoacoustic-microscopic-biopsy
#25
JOURNAL ARTICLE
Haigang Ma, Zhongwen Cheng, Zhiyang Wang, Haixia Qiu, Tianding Shen, Da Xing, Ying Gu, Sihua Yang
The ability to noninvasively acquire the fine structure of deep tissues is highly valuable but remains a challenge. Here, a photoacoustic microscopic biopsy (PAMB) combined switchable spatial-scale optical excitation with single-element depth-resolved acoustic detection mode was developed, which effectively coordinated the spatial resolution and the penetration depth for visualizations of skin delamination and chromophore structures up to reticular dermis depth, with the lateral resolution from 1.5 to 104 μm and the axial resolution from 34 to 57 μm...
October 1, 2021: Biomedical Optics Express
https://read.qxmd.com/read/34567587/a-primer-on-rhythm-quantification-for-fish-sounds-a-mediterranean-case-study
#26
JOURNAL ARTICLE
Lara S Burchardt, Marta Picciulin, Eric Parmentier, Marta Bolgan
We have used a lately established workflow to quantify rhythms of three fish sound types recorded in different areas of the Mediterranean Sea. So far, the temporal structure of fish sound sequences has only been described qualitatively. Here, we propose a standardized approach to quantify them, opening the path for assessment and comparison of an often underestimated but potentially critical aspect of fish sounds. Our approach is based on the analysis of inter-onset-intervals (IOIs), the intervals between the start of one sound element and the next...
September 2021: Royal Society Open Science
https://read.qxmd.com/read/34310297/model-based-x-ray-induced-acoustic-computed-tomography
#27
JOURNAL ARTICLE
Prabodh Kumar Pandey, Siqi Wang, Hari Om Aggrawal, Kristina Bjegovic, Salime Boucher, Liangzhong Xiang
X-ray induced acoustic computed tomography (XACT) provides X-ray absorption based contrast with acoustic detection. For its clinical translation, XACT imaging often has a limited field of view. This can result in image artifacts and overall loss of quantification accuracy. In this article, we aim to demonstrate model-based XACT image reconstruction to address these problems. An efficient matrix-free implementation of the regularized LSQR (MF-LSQR) based minimization scheme and a non-iterative model back-projection (MBP) scheme for computing XACT reconstructions have been demonstrated in this paper...
July 26, 2021: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://read.qxmd.com/read/34284932/quantification-of-liver-fat-content-with-ultrasound-a-wfumb-position-paper
#28
REVIEW
Giovanna Ferraioli, Annalisa Berzigotti, Richard G Barr, Byung I Choi, Xin Wu Cui, Yi Dong, Odd Helge Gilja, Jae Young Lee, Dong Ho Lee, Fuminori Moriyasu, Fabio Piscaglia, Katsutoshi Sugimoto, Grace Lai-Hung Wong, Vincent Wai-Sun Wong, Christoph F Dietrich
New ultrasound methods that can be used to quantitatively assess liver fat content have recently been developed. These quantitative ultrasound (QUS) methods are based on the analysis of radiofrequency echoes detected by the transducer, allowing calculation of parameters for quantifying the fat in the liver. In this position paper, after a section dedicated to the importance of quantifying liver steatosis in patients with non-alcoholic fatty liver disease and another section dedicated to the assessment of liver fat with magnetic resonance, the current clinical studies performed using QUS are summarized...
July 17, 2021: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/34197371/deep-learning-of-image-and-time-domain-data-enhances-the-visibility-of-structures-in-optoacoustic-tomography
#29
JOURNAL ARTICLE
Neda Davoudi, Berkan Lafci, Ali Özbek, Xosé Luís Deán-Ben, Daniel Razansky
Images rendered with common optoacoustic system implementations are often afflicted with distortions and poor visibility of structures, hindering reliable image interpretation and quantification of bio-chrome distribution. Among the practical limitations contributing to artifactual reconstructions are insufficient tomographic detection coverage and suboptimal illumination geometry, as well as inability to accurately account for acoustic reflections and speed of sound heterogeneities in the imaged tissues. Here we developed a convolutional neural network (CNN) approach for enhancement of optoacoustic image quality which combines training on both time-resolved signals and tomographic reconstructions...
July 1, 2021: Optics Letters
https://read.qxmd.com/read/34177758/putative-causal-variant-on-vlgr1-for-the-epileptic-phenotype-in-the-model-wistar-audiogenic-rat
#30
JOURNAL ARTICLE
Samara Damasceno, Pablo Augusto de Souza Fonseca, Izinara Cruz Rosse, Márcio Flávio Dutra Moraes, José Antônio Cortes de Oliveira, Norberto Garcia-Cairasco, Ana Lúcia Brunialti Godard
Wistar Audiogenic Rat is an epilepsy model whose animals are predisposed to develop seizures induced by acoustic stimulation. This model was developed by selective reproduction and presents a consistent genetic profile due to the several generations of inbreeding. In this study, we performed an analysis of WAR RNA-Seq data, aiming identified at genetic variants that may be involved in the epileptic phenotype. Seventeen thousand eighty-five predicted variants were identified as unique to the WAR model, of which 15,915 variants are SNPs and 1,170 INDELs...
2021: Frontiers in Neurology
https://read.qxmd.com/read/34140880/inhalation-of-molecular-hydrogen-a-rescue-treatment-for-noise-induced-hearing-loss
#31
JOURNAL ARTICLE
Anette Elisabeth Fransson, Pernilla Videhult Pierre, Mårten Risling, Göran Frans Emanuel Laurell
Noise exposure is the most important external factor causing acquired hearing loss in humans, and it is strongly associated with the production of reactive oxygen species (ROS) in the cochlea. Several studies reported that the administration of various compounds with antioxidant effects can treat oxidative stress-induced hearing loss. However, traditional systemic drug administration to the human inner ear is problematic and has not been successful in a clinical setting. Thus, there is an urgent need to develop rescue treatment for patients with acute acoustic injuries...
2021: Frontiers in Cellular Neuroscience
https://read.qxmd.com/read/34083642/quantitative-analysis-of-in-vivo-microbubble-distribution-in-the-human-brain
#32
JOURNAL ARTICLE
Francesco Prada, Antonio G Gennari, Ian M Linville, Michael E Mutersbaugh, Zhihang Chen, Natasha Sheybani, Francesco DiMeco, Frederic Padilla, John A Hossack
Microbubbles (MB) are widely used as contrast agents to perform contrast-enhanced ultrasound (CEUS) imaging and as acoustic amplifiers of mechanical bioeffects incited by therapeutic-level ultrasound. The distribution of MBs in the brain is not yet fully understood, thereby limiting intra-operative CEUS guidance or MB-based FUS treatments. In this paper we describe a robust platform for quantification of MB distribution in the human brain, allowing to quantitatively discriminate between tumoral and normal brain tissues and we provide new information regarding real-time cerebral MBs distribution...
June 3, 2021: Scientific Reports
https://read.qxmd.com/read/34023590/agglomeration-of-particles-by-a-converging-ultrasound-field-and-their-quantitative-assessments
#33
JOURNAL ARTICLE
Tianquan Tang, Bin Dong, Lixi Huang
The acoustic radiation force resulting from acoustic waves have been extensively studied for the contact-free generation of organized patterning arrays. The precise arrangement of microscopic objects clustered at the pressure nodes is critical to the development of functional structures and patterned surfaces. However, the size of the clusters is restricted by the saturation limit of the acoustic nodes. Here, we present a bulk acoustic wave (BAW) platform, which employs a two-dimensional acoustic wave to propel particles of various sizes...
May 17, 2021: Ultrasonics Sonochemistry
https://read.qxmd.com/read/33794784/a-randomised-placebo-controlled-trial-of-vsl-3-%C3%A2-probiotic-on-biomarkers-of-cardiovascular-risk-and-liver-injury-in-non-alcoholic-fatty-liver-disease
#34
JOURNAL ARTICLE
Pui Lin Chong, David Laight, Richard J Aspinall, Antony Higginson, Michael H Cummings
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular risk irrespective of conventional risk factors. The role of gut-liver interaction is implicated in its development. We investigated the effects of VSL#3® probiotic supplementation on biomarkers of cardiovascular risk and liver injury in patients with NAFLD. METHODS: A randomised, double-blinded, placebo-controlled, proof-of-concept study was undertaken. Patients with NAFLD were randomly allocated to take 2 sachets VSL#3® probiotic or placebo twice daily for 10 weeks...
April 1, 2021: BMC Gastroenterology
https://read.qxmd.com/read/33551194/cardiac-mr-imaging-of-muscular-dystrophies
#35
REVIEW
Felipe Sanchez, Carolina Weitz, Jose M Gutierrez, Luisa Mestroni, Kate Hanneman, Daniel Vargas
Muscular dystrophies (MDs) are a group of inherited disorders caused by mutations that interfere with muscular structure, contraction, or relaxation. As the cardiac sarcomeric unit shares multiple proteins with the skeletal muscle unit, the heart is affected in several MDs, sometimes without apparent musculoskeletal involvement. Early detection of MD-related cardiomyopathy is crucial as timely initiation of cardioprotective therapy can slow adverse cardiac remodeling. Although transthoracic echocardiography is widely used for the evaluation of cardiac morphology and function, it has limitations in terms of reproducibility and image quality...
January 9, 2021: Current Problems in Diagnostic Radiology
https://read.qxmd.com/read/33109381/ultrasound-detection-of-liver-fibrosis-in-individuals-with-hepatic-steatosis-using-the-homodyned-k-distribution
#36
JOURNAL ARTICLE
Yu-Wei Tsai, Zhuhuang Zhou, Cihun-Siyong Alex Gong, Dar-In Tai, Anca Cristea, Yu-Ching Lin, Ya-Chun Tang, Po-Hsiang Tsui
Acoustic structure quantification (ASQ) based on the analysis of ultrasound backscattered statistics has been reported to detect liver fibrosis without significant hepatic steatosis. This study proposed using ultrasound parametric imaging based on the parameter α of the homodyned K (HK) distribution for staging liver fibrosis in patients with significant hepatic steatosis. Raw ultrasound image data were acquired from patients (n = 237) to construct B-mode and HK α parametric images, which were compared with the focal disturbance (FD) ratio obtained from ASQ on the basis of histologic evidence (METAVIR fibrosis score and hepatic steatosis severity)...
January 2021: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/33079081/rapid-capture-of-biomolecules-from-blood-via-stimuli-responsive-elastomeric-particles-for-acoustofluidic-separation
#37
JOURNAL ARTICLE
Linying Li, C Wyatt Shields, Jin Huang, Yiqun Zhang, Korine A Ohiri, Benjamin B Yellen, Ashutosh Chilkoti, Gabriel P López
The detection of biomarkers in blood often requires extensive and time-consuming sample preparation to remove blood cells and concentrate the biomarker(s) of interest. We demonstrate proof-of-concept for a chip-based, acoustofluidic method that enables the rapid capture and isolation of a model protein biomarker (i.e., streptavidin) from blood for off-chip quantification. Our approach makes use of two key components - namely, soluble, thermally responsive polypeptides fused to ligands for the homogeneous capture of biomarkers from whole blood and silicone microparticles functionalized with similar, tethered, thermally responsive polypeptides...
October 20, 2020: Analyst
https://read.qxmd.com/read/33009414/evolution-of-communication-signals-and-information-during-species-radiation
#38
JOURNAL ARTICLE
Maxime Garcia, Frédéric Theunissen, Frédéric Sèbe, Julien Clavel, Andrea Ravignani, Thibaut Marin-Cudraz, Jérôme Fuchs, Nicolas Mathevon
Communicating species identity is a key component of many animal signals. However, whether selection for species recognition systematically increases signal diversity during clade radiation remains debated. Here we show that in woodpecker drumming, a rhythmic signal used during mating and territorial defense, the amount of species identity information encoded remained stable during woodpeckers' radiation. Acoustic analyses and evolutionary reconstructions show interchange among six main drumming types despite strong phylogenetic contingencies, suggesting evolutionary tinkering of drumming structure within a constrained acoustic space...
October 2, 2020: Nature Communications
https://read.qxmd.com/read/32939866/high-sensitivity-acoustic-molecular-sensors-based-on-large-area-spray-coated-2d-covalent-organic-frameworks
#39
JOURNAL ARTICLE
Austin M Evans, Nathan P Bradshaw, Brian Litchfield, Michael J Strauss, Bethany Seckman, Matthew R Ryder, Ioannina Castano, Christopher Gilmore, Nathan C Gianneschi, Catherine R Mulzer, Mark C Hersam, William R Dichtel
2D covalent organic frameworks (2D COFs) are a unique materials platform that combines covalent connectivity, structural regularity, and molecularly precise porosity. However, 2D COFs typically form insoluble aggregates, thus limiting their processing via additive manufacturing techniques. In thiswork, colloidal suspensions of boronate-ester-linked 2D COFs as a spray-coating ink to produce large-area 2D COF thin films is used. This method is synthetically general, with five different 2D COFs prepared as colloidal inks and subsequently spray-coated onto a diverse range of substrates...
September 16, 2020: Advanced Materials
https://read.qxmd.com/read/32556526/endoscopic-endonasal-and-transorbital-routes-to-the-petrous-apex-anatomic-comparative-study-of-two-pathways
#40
JOURNAL ARTICLE
Thomaz E Topczewski, Alberto Di Somma, Jose Pineda, Abel Ferres, Jorge Torales, Luis Reyes, Ruben Morillas, Domenico Solari, Luigi Maria Cavallo, Paolo Cappabianca, Joaquim Enseñat, Alberto Prats-Galino
BACKGROUND AND OBJECTIVE: Surgical approaches to the petrous apex region are extremely challenging; while subtemporal approaches and variations represent the milestone of the surgical modules to reach such deep anatomical target, in a constant effort to develop minimally invasive neurosurgical routes, the endoscopic endonasal approach (EEA) has been tested to get a viable corridor to the petroclival junction. Lately, another ventral endoscopic minimally invasive route, i.e., the superior eyelid endoscopic transorbital approach, has been proposed to access the most lateral aspect of the skull base, including the petrous apex region...
June 15, 2020: Acta Neurochirurgica
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