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https://www.readbyqxmd.com/read/29145648/relative-performance-of-hpv-and-cytology-components-of-cotesting-in-cervical-screening
#1
Mark Schiffman, Walter K Kinney, Li C Cheung, Julia C Gage, Barbara Fetterman, Nancy E Poitras, Thomas S Lorey, Nicolas Wentzensen, Brian Befano, John Schussler, Hormuzd A Katki, Philip E Castle
Background: The main goal of cervical screening programs is to detect and treat precancer before cancer develops. Human papillomavirus (HPV) testing is more sensitive than cytology for detecting precancer. However, reports of rare HPV-negative, cytology-positive cancers are motivating continued use of both tests (cotesting) despite increased testing costs. Methods: We quantified the detection of cervical precancer and cancer by cotesting compared with HPV testing alone at Kaiser Permanente Northern California (KPNC), where 1 208 710 women age 30 years and older have undergone triennial cervical cotesting since 2003...
November 14, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29145611/identification-of-novel-potentially-pleiotropic-variants-associated-with-osteoporosis-and-obesity-using-cfdr-method
#2
Yuan Hu, Li-Jun Tan, Xiang-Ding Chen, Zhen Liu, Shi-Shi Min, Qin Zeng, Hui Shen, Hong-Wen Deng
Context: Genome-wide association studies (GWASs) have been successful in identifying loci associated with osteoporosis and obesity. However, the findings just explain a small fraction of the total genetic variance. Objective: The aim of this study was to identify novel pleiotropic genes important in osteoporosis and obesity. Design and Setting: A pleiotropic conditional false discovery rate (cFDR) method was applied to three independent GWAS summary statistics of femoral neck bone mineral density (FN BMD), body mass index (BMI) and waist-hip ratio (WHR)...
November 14, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29145570/tooth-wear-and-gingival-recession-in-210-orthodontically-treated-patients-a-retrospective-cohort-study
#3
Marco Mijuskovic, Meret C Gebistorf, Nikolaos Pandis, Anne M Renkema, Piotr S Fudalej
Aim: To assess the association between tooth wear (TW) and gingival recession (GR). Materials and Methods: Two hundred and ten orthodontically treated participants (100 males) were evaluated. GR and TW were rated independently by four raters on plaster models at four time points: before treatment (T1), mean age 13.8 years (SD = 3.7); after treatment (T2), mean age 16.7 years (SD = 3.9); 3 years after treatment (T3), mean age 19.7 years (SD = 4.2); and 7 years after treatment (T4), mean age 23...
November 14, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/29145527/evaluation-of-operating-time-and-patient-perception-using-conventional-impression-taking-and-intraoral-scanning-for-crown-manufacture-a-split-mouth-randomized-clinical-study
#4
Yasser Haddadi, Golnosh Bahrami, Flemming Isidor
PURPOSE: To compare operating time and patient perception of conventional impression (CI) taking and intraoral scanning (IOS) for manufacture of a tooth-supported crown. MATERIALS AND METHODS: A total of 19 patients needing indirect full-coverage restorations fitting the requirements for a split-mouth design were recruited. Each patient received two lithium disilicate crowns, one manufactured from CI taking and one from IOS. Both teeth were prepared following the manufacturers' recommendations...
November 16, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/29145461/climate-change-mitigation-opportunities-based-on-carbon-footprint-estimates-of-dietary-patterns-in-peru
#5
Ian Vázquez-Rowe, Gustavo Larrea-Gallegos, Pedro Villanueva-Rey, Alessandro Gilardino
Food consumption accounts for an important proportion of the world GHG emissions per capita. Previous studies have delved into the nature of dietary patterns, showing that GHG reductions can be achieved in diets if certain foods are consumed rather than other, more GHG intensive products. For instance, vegetarian and low-meat diets have proved to be less carbon intensive than diets that are based on ruminant meat. These environmental patterns, increasingly analyzed in developed nations, are yet to be assessed in countries liked Peru where food purchase represents a relatively high percentage of the average household expenditure, ranging from 38% to 51% of the same...
2017: PloS One
https://www.readbyqxmd.com/read/29145425/statistical-analysis-of-co-occurrence-patterns-in-microbial-presence-absence-datasets
#6
Kumar P Mainali, Sharon Bewick, Peter Thielen, Thomas Mehoke, Florian P Breitwieser, Shishir Paudel, Arjun Adhikari, Joshua Wolfe, Eric V Slud, David Karig, William F Fagan
Drawing on a long history in macroecology, correlation analysis of microbiome datasets is becoming a common practice for identifying relationships or shared ecological niches among bacterial taxa. However, many of the statistical issues that plague such analyses in macroscale communities remain unresolved for microbial communities. Here, we discuss problems in the analysis of microbial species correlations based on presence-absence data. We focus on presence-absence data because this information is more readily obtainable from sequencing studies, especially for whole-genome sequencing, where abundance estimation is still in its infancy...
2017: PloS One
https://www.readbyqxmd.com/read/29145351/comparison-of-treatment-of-acute-unstable-distal-clavicle-fractures-using-anatomical-locking-plates-with-versus-without-additional-suture-anchor-fixation
#7
Jixing Fan, Yufu Zhang, Qiang Huang, Xieyuan Jiang, Liang He
BACKGROUND Surgical managements were recommended for unstable distal clavicle fracture owing to the high incidence of nonunion. The present study compared the efficacy of anatomical locking plate with versus without additional suture anchor fixation for the treatment of unstable Neer type II distal clavicle fractures. MATERIAL AND METHODS Between January 2013 to January 2015, 28 consecutive patients with unstable Neer type II  fractures were treated by using anatomical locking plate with or without additional suture anchor fixation...
November 16, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29145288/efficacy-of-cold-application-on-pain-during-chest-tube-removal-a-randomized-controlled-trial-a-consort-compliant-article
#8
Ling-Yu Hsieh, Yi-Rong Chen, Mei-Chun Lu
BACKGROUND: Use of analgesics is the most common method to alleviate the pain induced by chest tube removal (CTR), but patient response to medication can vary and may not be achieved complete relaxation. This study was to determine the effectiveness of cold application in combination with standard analgesic administration before CTR on CTR-induced pain. METHODS: A prospective, randomized, single-blind, sham-controlled study was conducted. In addition to the same routine care, subjects in the experimental group (n = 30) received cold application of 600-g ice packs 15 minutes before CTR, whereas subjects in the sham group (n = 30) received tap water packs...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144964/biocultural-approach-of-the-association-between-maturity-and-physical-activity-in-youth
#9
André O Werneck, Danilo R P Silva, Paul Collings, Rômulo A Fernandes, Enio R V Ronque, Manuel J Coelho-E-Silva, Luís B Sardinha, Edilson S Cyrino
OBJECTIVE: To test the biocultural model through direct and indirect associations between biological maturation, adiposity, cardiorespiratory fitness, sadness, social relationships, and physical activity in adolescents. METHODS: This was a cross-sectional study conducted with 1152 Brazilian adolescents aged between 10 and 17 years. Somatic maturation was estimated through Mirwald's method (peak height velocity). Physical activity was assessed through Baecke questionnaire (occupational, leisure, and sport contexts)...
November 13, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/29144767/evaluation-of-polyvinyl-caprolactam-polyvinyl-acetate-polyethylene-glycol-graft-copolymer-nanomicelle-for-trigeminal-ganglion-neurons-delivering-with-intranasal-administration
#10
Mengshuang Li, Meng Xin, Kaichao Song, Fengyuan Sun, Yuzhen Hou, Jun Li, Xianggen Wu
Purpose How to deliver enough medical agents to the trigeminal ganglion (TG) neurons conveniently still remains a challenge in pharmaceutics and clinics. The purpose of this study was to reveal that intranasal administration of polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer (PVCL-PVA-PEG) nanomicelle formulation could efficiently deliver agent to TG neurons in mice. Methods Ocular topical or intranasal administration of nanomicelle coumarin-6 was performed in mice, and tissue distribution after administration (0...
November 16, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29144546/presence-of-infection-and-analysis-of-hpv-subtypes-in-girls-younger-than-9-years-old-attended-at-a-referral-service-in-esp%C3%A3-rito-santo-brazil
#11
Mariana Penha De Nadai Sartori, Lidiane Pignaton Agostini, Thaís Tristão Tovar, Raquel Silva Dos Reis, Raquel Spinassé Dettogni, Eldamária de Vargas Wolfgramm Dos Santos, Antônio Chambô Filho, Iúri Drumond Louro
PURPOSE: Human papillomavirus is found in adults and adolescents and is associated with genital warts and cervical cancer. However, it has been detected in girls younger than 10 years old. Currently, there are no prevention methods for this age group, since it is not considered a risk group. The aim of this study was to evaluate the presence of infection and HPV subtype in girls under 9 years old attended at a referral service in the State of Espírito Santo, Brazil. METHODS: Forty-three girls younger than 9 years old had gynecological brush samples collected from vulval and perineal/anal regions...
November 16, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/29144535/a-health-economic-outcome-evaluation-of-an-internet-based-mobile-supported-stress-management-intervention-for-employees
#12
David Daniel Ebert, Fanny Kählke, Claudia Buntrock, Matthias Berking, Filip Smit, Elena Heber, Harald Baumeister, Burkhardt Funk, Heleen Riper, Dirk Lehr
Objective This study aimed to estimate and evaluate the cost-effectiveness and cost-benefit of a guided internet- and mobile-supported occupational stress-management intervention (iSMI) for employees from the employer's perspective alongside a randomized controlled trial. Methods A sample of 264 employees with elevated symptoms of perceived stress (Perceived Stress Scale, PSS-10 ≥22) was randomly assigned either to the iSMI or a waitlist control (WLC) group with unrestricted access to treatment as usual. The iSMI consisted of seven sessions of problem-solving and emotion-regulation techniques and one booster session...
November 16, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/29144223/no-touch-disinfection-methods-to-decrease-multidrug-resistant-organism-infections-a-systematic-review-and-meta-analysis
#13
Alexandre R Marra, Marin L Schweizer, Michael B Edmond
BACKGROUND Recent studies have shown that using no-touch disinfection technologies (ie, ultraviolet light [UVL] or hydrogen peroxide vapor [HPV] systems) can limit the transmission of nosocomial pathogens and prevent healthcare-associated infections (HAIs). To investigate these findings further, we performed a systematic literature review and meta-analysis on the impact of no-touch disinfection methods to decrease HAIs. METHODS We searched PubMed, CINAHL, CDSR, DARE and EMBASE through April 2017 for studies evaluating no-touch disinfection technology and the nosocomial infection rates for Clostridium difficile, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and other multidrug-resistant organisms (MDROs)...
November 16, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29143785/waterborne-polyurethane-coatings-with-covalently-linked-black-dye-sudan-black-b
#14
Tao Wang, Wei Sun, Xingyuan Zhang, Haiyan Xu, Fei Xu
Colored waterborne polyurethanes have been widely used in paintings, leathers, textiles, and coatings. Here, a series of black waterborne polyurethanes (WPUs) with different ratios of black dye, Sudan Black B (SDB), were prepared by step-growth polymerization. WPU emulsions as obtained exhibit low particle sizes and remarkable storage stability at the same time. At different dye loadings, essential structural, statistical and thermal properties are characterized. FTIR (fourier transform infrared) spectra indicate that SDB is covalently linked into waterborne polyurethane chains...
October 28, 2017: Materials
https://www.readbyqxmd.com/read/29143772/fault-detection-of-bearing-systems-through-eemd-and-optimization-algorithm
#15
Dong-Han Lee, Jong-Hyo Ahn, Bong-Hwan Koh
This study proposes a fault detection and diagnosis method for bearing systems using ensemble empirical mode decomposition (EEMD) based feature extraction, in conjunction with particle swarm optimization (PSO), principal component analysis (PCA), and Isomap. First, a mathematical model is assumed to generate vibration signals from damaged bearing components, such as the inner-race, outer-race, and rolling elements. The process of decomposing vibration signals into intrinsic mode functions (IMFs) and extracting statistical features is introduced to develop a damage-sensitive parameter vector...
October 28, 2017: Sensors
https://www.readbyqxmd.com/read/29143389/clinical-and-radiologic-outcomes-of-submerged-and-nonsubmerged-bone-level-implants-with-internal-hexagonal-connections-in-immediate-implantation-a-5-year-retrospective-study
#16
Shiyu Wu, Xiayi Wu, Rachana Shrestha, Jinying Lin, Zhicai Feng, Yudong Liu, Yunlin Shi, Baoxin Huang, Zhipeng Li, Quan Liu, Xiaocong Zhang, Mingxuan Hu, Zhuofan Chen
PURPOSE: To evaluate the 5-year clinical and radiologic outcome of immediate implantation using submerged and nonsubmerged techniques with bone-level implants and internal hexagonal connections and the effects of potential influencing factors. MATERIALS AND METHODS: A total of 114 bone-level implants (XiVE S plus) with internal hexagonal connections inserted into 72 patients were included. Patients were followed up for 5 years. A t-test was used to statistically evaluate the marginal bone loss between the submerged and nonsubmerged groups...
November 16, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29143363/utility-of-shear-wave-elastography-for-assessing-allograft-fibrosis-in-renal-transplant-recipients-a-pilot-study
#17
Heather M Early, Ellen C Cheang, Jorge M Aguilera, Jonah S W Hirschbein, Ghaneh Fananapazir, Machelle D Wilson, John P McGahan
OBJECTIVES: To evaluate the utility of ultrasound-based shear wave elastography (SWE) as a noninvasive method to accurately detect and potentially stage the severity of renal allograft fibrosis and assess its user reproducibility. METHODS: In this Institutional Review Board-approved, Health Insurance Portability and Accountability Act-compliant prospective study, 70 renal transplant recipients underwent an SWE evaluation of their allograft followed directly by biopsy...
November 16, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29143324/bioelectrical-impedance-as-a-technique-for-estimating-postmortem-interval
#18
Eriek S Hansen, Christiane Baigent, Sophia I Reck, Melissa Connor
Estimation of postmortem interval (PMI) is a critical component of death investigation. A cadaver can be hypothesized to be a resistor-capacitor (RC) circuit the impedance (Z) of which changes in a quantifiable manner as the cadaver decomposes. This hypothesis was tested using bioelectrical impedance analysis (BIA) equipment to apply a current with a fixed amplitude at a single frequency to four cadavers over time and measuring two components of Z, resistance (R) and reactance (Xc ). Quadratic regression analysis between Z and accumulated degree days (ADD) showed a statistically significant parabolic relationship...
November 16, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29143224/investigation-of-dna-transfer-onto-clothing-during-regular-daily-activities
#19
Travis Ruan, Mark Barash, Peter Gunn, David Bruce
Low levels of DNA from an unidentified human source, often referred to as trace DNA, are ubiquitous, can be transferred onto objects by either direct or indirect methods and have an unknown longevity in situ. Clothing items from crime scenes are often submitted for trace DNA analysis, usually in attempt to identify a person of interest. This study examined the transfer of DNA onto three 10 × 10 cm areas located on the front, back and shoulder of an individual's external clothing (n = 300) during a regular day's activity...
November 15, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29142891/assessment-of-severity-of-malnutrition-in-peritoneal-dialysis-patients-via-malnutrition-inflammatory-score
#20
Afsoon Emami Naeeni, Nazila Poostiyan, Zahra Teimouri, Mojgan Mortazavi, Mojgan Soghrati, Elnaz Poostiyan, Zamzam Paknahad
Background: Regarding to the complications of malnutrition in dialysis patients, using an easy and reliable method for evaluating of malnutrition is important in patients with the end-stage renal disease. Based on the effect of inflammatory factors in malnutrition, A new scale has been designed which is called malnutrition-inflammatory scale (MIS). We designed current study to assess the severity of malnutrition in peritoneal dialysis patients in Isfahan via MIS. Materials and Methods: In this cross-sectional MIS was used for evaluation of malnutrition...
2017: Advanced Biomedical Research
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