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Ventricles

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https://www.readbyqxmd.com/read/28645847/cardiovascular-morphometry-with-high-resolution-3d-magnetic-resonance-first-application-to-left-ventricle-diastolic-dysfunction
#1
Diego Gallo, Orestis Vardoulis, Pierre Monney, Davide Piccini, Panagiotis Antiochos, Juerg Schwitter, Nikolaos Stergiopulos, Umberto Morbiducci
In this study, an image-based morphometry toolset quantifying geometric descriptors of the left ventricle, aorta and their coupling is applied to investigate whether morphological information can differentiate between subjects affected by diastolic dysfunction (patient group) and their age-matched controls (control group). The ventriculo-aortic region of 20 total participants (10 per group) were segmented from high-resolution 3D magnetic resonance images, from the left ventricle to the descending aorta. Each geometry was divided into segments in correspondence of anatomical landmarks...
June 21, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28645596/endoscopic-removal-of-a-bullet-migrated-to-the-third-ventricle-causing-hydrocephalus-a-case-report
#2
Aydın Aydoseli, Tugrul Cem Unal, Yavuz Aras, Pulat Akın Sabanci, Emre Altunrende, Nail Izgi
Hydrocephalus caused by an intraventricular bullet is a rare event. We report a case of a man aged 66 years who was admitted to hospital after a suicide attempt with gunshot to the head. The bullet migrated from the frontal parenchyma to the 3rd ventricle 4 days later. On the 21st day of admission, the patient developed hydrocephalus with obstruction of aqueduct. The bullet was then accessed through an endoscopic third ventriculostomy and removed using an endoscope. This is the first case in the literature of foreign object removal from the ventricle via a transcortical endoscopic approach...
June 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28645590/endoscopic-supracerebellar-transtentorial-approach-to-the-atrium-of-the-lateral-ventricle-preliminary-surgical-and-optical-considerations
#3
Tao Xie, Linjun Zhou, Xiaobiao Zhang, Wei Sun, Hailin Ding, Tengfei Liu, Ye Gu, Chongjing Sun, Fan Hu, Wei Zhu
OBJECTIVE: To report the operative techniques of the endoscopic supracerebellar transtentorial approach (ESTA) to the atrium of the lateral ventricle, especially focusing on the role of the endoscope and analyzing optically related issues. METHODS: A retrospective data review was performed on five patients with lesions in the atrium of the lateral ventricle undergoing the ESTA. The patients were positioned in the three-quarters prone position, and a paramidline linear incision was used...
June 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28645293/prenatal-screening-of-fetal-ventriculoarterial-connections-benefits-of-4d-technique-in-fetal-heart-imaging
#4
Yu Wang, Miao Fan, Faiza Amber Siddiqui, Meilian Wang, Wei Sun, Xue Sun, Wenjia Lei, Ying Zhang
BACKGROUND: Identification of prenatal ventriculoarterial connections in fetuses with conotruncal anomalies (CTA) remains one of the greatest challenges for sonographers performing screening examinations. Herein, we propose a novel protocol of 4D volume analysis that identifies ventriculoarterial connections and evaluate its clinical utility in routine screenings. METHODS: Twenty-nine cases of transposition of the great arteries (TGA), 22 cases of double-outlet right ventricle (DORV), 36 cases of tetralogy of Fallot (TOF), 14 cases of truncus arteriosus (TCA), and randomly selected 70 normal fetuses were reviewed in this study...
June 23, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28645241/long-term-outcome-after-right-ventricle-to-pulmonary-artery-conduit-surgery-and-reintervention
#5
Kristofer Skoglund, Gunnar Svensson, Ulf Thilén, Mikael Dellborg, Peter Eriksson
BACKGROUND: Reconstruction of the right ventricular outflow tract with a conduit is an established surgical procedure in congenital heart disease and reinterventions are common. OBJECTIVE: An increasing number of patients have a conduit, but there are few population-based studies of long-term outcomes after conduit surgery, reoperations, and transcatheter pulmonary valve replacement. METHODS: In April 2015, all adult patients with a conduit were identified in the Swedish National Registry for Congenital Heart Disease (SWEDCON)...
June 23, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/28645012/associations-between-toxic-and-essential-trace-elements-in-maternal-blood-and-fetal-congenital-heart-defects
#6
Yanqiu Ou, Michael S Bloom, Zhiqiang Nie, Fengzhen Han, Jinzhuang Mai, Jimei Chen, Shao Lin, Xiaoqing Liu, Jian Zhuang
Prenatal exposure to toxic trace elements, including heavy metals, is an important public health concern. Few studies have assessed if individual and multiple trace elements simultaneously affect cardiac development. The current study evaluated the association between maternal blood lead (Pb), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), and selenium (Se) levels and congenital heart defects (CHDs) in offspring. This hospital-based case-control study included 112 case and 107 control infants. Maternal peripheral blood draw was made during gestational weeks 17-40 and used to determine trace element levels by inductively coupled plasma mass spectrometry...
June 20, 2017: Environment International
https://www.readbyqxmd.com/read/28644061/diffusion-weighted-magnetic-resonance-imaging-in-the-assessment-of-choroid-plexus-aging
#7
Banu Alicioglu, Guliz Yilmaz, Ozgur Tosun, Nail Bulakbasi
Recent studies have pointed out dysfunction and histopathological changes of the choroid plexuses (CPs) with aging. This paper reviews apparent diffusion coefficient (ADC) values of the CPs for age-related changes. All the brain MR images of the patients between January 2013 and June 2014 in our Radiology Department were retrospectively investigated. Patients with major cranial abnormalities (brain tumors, hyperacute or acute ischemia, developmental anomalies, hemorrhage, hydrocephaly) were excluded. Diffusion-weighted images were obtained at the parameter values of b = 1000 s/mm(2) in the axial plane...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28643402/clinical-findings-in-right-ventricular-noncompaction-in-hypoplastic-left-heart-syndrome
#8
Monique M Gardner, Meryl S Cohen
BACKGROUND: Noncompaction is a poorly understood form of cardiomyopathy that typically affects the left ventricle and may be associated with congenital heart disease. Right ventricular noncompaction (RVNC) may occur when the left ventricle is affected but is rarely seen in isolation. RVNC may have clinical significance affecting surgical and long-term outcomes. We describe the diagnosis and clinical course in three patients at our institution. METHODS: We performed a retrospective review of patients diagnosed with RVNC over a 12-month period at our institution and reviewed their imaging and clinical course...
June 23, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28643339/ruptured-ventricular-septum-dissection-into-the-right-ventricle
#9
Yuta Kanazawa, Yasuyuki Yamada, Yusuke Takei, Hirotsugu Fukuda
No abstract text is available yet for this article.
June 23, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28643039/primary-intraventricular-meningiomas-in-children-experience-of-two-cases-with-review-of-literature
#10
Kapil D Muley, Salman T Shaikh, Chandrashekhar E Deopujari, Uday B Andar
Meningiomas are rare in the pediatric age group, more so in the intraventricular location. They arise in the lateral ventricles from the arachnoid cells contained within the choroid plexus, in the third ventricle from the velum interpositum and in the fourth ventricle from the choroids. These tumors are usually large and have an aggressive behaviour. Surgical management of intra-ventricular meningiomas is challenging because of their deep location, large size at presentation and increased vascularity. The authors report two such cases who presented with symptoms of raised intra cranial pressure and on evaluation were found to have associated hydrocephalus...
June 22, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28642964/metastasis-of-breast-cancer-cells-to-the-bone-lung-and-lymph-nodes-promotes-resistance-to-ionizing-radiation
#11
Takamitsu Hara, Manabu Iwadate, Kazunoshin Tachibana, Satoshi Waguri, Seiichi Takenoshita, Nobuyuki Hamada
BACKGROUND: Metastasis represents the leading cause of breast cancer deaths, necessitating strategies for its treatment. Although radiotherapy is employed for both primary and metastatic breast cancers, the difference in their ionizing radiation response remains incompletely understood. This study is the first to compare the radioresponse of a breast cancer cell line with its metastatic variants and report that such metastatic variants are more radioresistant. MATERIALS AND METHODS: A luciferase expressing cell line was established from human basal-like breast adenocarcinoma MDA-MB-231 and underwent in vivo selections, whereby a cycle of inoculations into the left cardiac ventricle or the mammary fat pad of athymic nude mice, isolation of metastases to the bone, lung and lymph nodes visualized with bioluminescence imaging, and expansion of obtained cells was repeated twice or three times...
June 22, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28642175/subventricular-zone-involvement-characterised-by-dti-in-glioblastoma
#12
Bart Rj van Dijken, Jiun-Lin Yan, Natalie R Boonzaier, Chao Li, Peter Jan van Laar, Anouk van der Hoorn, Stephen J Price
BACKGROUND: Glioblastomas have a poor prognosis, possibly due to a subpopulation of therapy resistant stem cells within the heterogeneous glioblastoma. As the subventricular zone is the main source of neural stem cells, we aimed at characterising the subventricular zone using DTI to demonstrate subventricular zone involvement in glioblastoma. METHODS: We prospectively included 93 patients with primary glioblastomas who underwent preoperative DTI. The non-enhancing high FLAIR signal was used to describe the infiltrative tumour margin...
June 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28641799/the-continued-search-for-physiological%C3%A2-pacing-where-are-we-now
#13
REVIEW
Pugazhendhi Vijayaraman, Pierre Bordachar, Kenneth A Ellenbogen
Cardiac pacing is an effective treatment for patients with bradycardia due to sinus node dysfunction or atrioventricular block. Despite decades of technological advances, the optimal ventricular pacing site to mimic normal human ventricular physiology and best hemodynamic response remains elusive. Beginning with atrial synchronous right ventricular (RV) apical pacing, the search has continued through alternate RV pacing sites, minimizing RV pacing, biventricular pacing, left ventricular (LV) pacing, and His-bundle pacing...
June 27, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28641510/recent-advances-on-the-role-of-neurogenesis-in-the-adult-brain-therapeutic-potential-in-parkinson-s-and-alzheimer-s-diseases
#14
Khaled Salman Radad, Rudolf Moldzio, Mubarak Al-Shraim, Barbara Kranner, Christopher Krewenka, Wolf-Dieter Rausch
Generation of nascent functional neurons from neural stem cells in the adult brain has recently become largely accepted by the neuroscience community. In adult mammals including humans, the process of neurogenesis has been well documented in two brain regions; the subventricular zone of the lateral ventricles and the subgranular zone in the dentate gyrus of the hippocampus. Some evidence has indicated neurogenesis in other regions of the adult mammalian brain such as the neocortex, cerebellum, striatum, amygdala and hypothalamus...
June 22, 2017: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/28641243/ecurves-a-temporal-shape-encoding
#15
Elena Bernardis, Yong Zhang, Ender Konukoglu, Yangming Ou, Harold Javitz, Leon Axel, Dimitris N Metaxas, Benoit Desjardins, Kilian M Pohl
OBJECTIVE: This paper presents a framework for temporal shape analysis to capture the shape and changes of anatomical structures from 3D+t(ime) medical scans. METHOD: We first encode the shape of a structure at each time point with the spectral signature, i.e., the eigenvalues and eigenfunctions of the Laplace operator. We then expand it to capture morphing shapes by tracking the eigenmodes across time according to the similarity of their eigenfunctions. The similarity metric is motivated by the fact that small shape deformations lead to minor changes in the eigenfunctions...
June 16, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28641192/obstructive-neonatal-atrial-myxoma
#16
Federica Iezzi, Andrea Quarti, Alessandro Capestro, Marco Pozzi
INTRODUCTION: Cardiac myxoma is a benign neoplasm representing the most common primary cardiac tumor in adults, however it is unusual in neonates. It is represented by an endocardial mass that occupies the cardiac chamber. Although the majority of myxomas are attached to the fossa ovalis of the interatrial septum, they also attach to the walls of the cardiac chambers and to valve leaflets surfaces. Approximately 75% of myxomas are found in the left atrium, 20% are located in the right atrium, and rarely in the ventricles...
June 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28640873/healthy-aging-of-the-left-ventricle-in-relationship-to-cardiovascular-risk-factors-the-multi-ethnic-study-of-atherosclerosis-mesa
#17
Chia-Ying Liu, Shenghan Lai, Nadine Kawel-Boehm, Harjit Chahal, Bharath Ambale-Venkatesh, Joao A C Lima, David A Bluemke
BACKGROUND: Understanding the relationship of cardiovascular structure and function to age is confounded by the high prevalence of traditional risk factors in the United States. The purpose of the study is to compare left ventricular (LV) and aortic structural, and functional parameters in individuals with and without traditional risk factors in a population-based cohort. METHODS AND RESULTS: 3015 study participants (48% men, age 55-94, mean 69.01±9.17 years) in the Multi-Ethnic Study of Atherosclerosis (MESA) underwent cardiovascular magnetic resonance (CMR) imaging from 2010-2012...
2017: PloS One
https://www.readbyqxmd.com/read/28639048/evaluating-anorexia-related-brain-atrophy-using-mp2rage-based-morphometry
#18
José Boto, Georgios Gkinis, Alexis Roche, Tobias Kober, Bénédicte Maréchal, Nadia Ortiz, Karl-Olof Lövblad, François Lazeyras, Maria Isabel Vargas
AIM: To evaluate brain atrophy in anorexic patients by automated cerebral segmentation with the magnetization-prepared 2 rapid acquisition gradient echo (MP2RAGE) MRI sequence. MATERIAL AND METHODS: Twenty patients (female; mean age, 27.9 years), presenting consecutively for brain MRI between August 2014-December 2016 with clinical suspicion of anorexia nervosa and BMI<18.5 kg/m(2) were included. Controls were ten healthy females (mean age, 26.5 years). Automated brain morphometry was performed based on MP2RAGE...
June 21, 2017: European Radiology
https://www.readbyqxmd.com/read/28638918/-generation-of-tnnt2a-knock-out-zebrafish-via-crispr-cas9-and-phenotypic-analysis
#19
Lian Liu, Ran-Ran Zhang, Qian Yang, Xu Wang, Yong-Hao Gui
Cardiac troponin T (cTnT) serves as a structural protein of myocardial fiber, and participates in heart excitation-contraction coupling process. Here, we generated tnnt2a (cTnT-coding gene) deletion mutant zebrafish via CRISPR/Cas9 technique, and performed phenotypic analysis of the identified tnnt2a mutants. We observed that there was no significant difference between heterozygous mutant and wild type zebrafish, and the homozygous mutants displayed significant malformations in heart, including cardiac arrest, atrium and ventricle enlargement, pericardium effusion, and the individuals usually died before 7 day post fertilization (dpf)...
June 25, 2017: Sheng Li Xue Bao: [Acta Physiologica Sinica]
https://www.readbyqxmd.com/read/28638839/broken-heart-syndrome-in-a-patient-on-maintenance-hemodialysis
#20
Sukhdeep Bhogal, Vatsal Ladia, Puja Sitwala, Kailash Bajaj, Vijay Ramu, Timir Paul
Context:Broken heart syndrome or Takotsubo cardiomyopathy (TC) is a disorder characterized by transient left ventricular apical ballooning that almost invariably precedes emotional or physical stress. Although the patients with chronic kidney disease on hemodialysis have shown to exhibit sustained activity of sympathetic nervous system, the presentation of TC in these patients is a rare entity with few case reports in the literature. Case Report: A 75-year-old female with past medical history of end-stage renal disease presented with chest pressure and heaviness that started during her maintenance hemodialysis session...
April 2017: Journal of Investigative Medicine High Impact Case Reports
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