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https://www.readbyqxmd.com/read/27774104/arterial-stiffness-in-nonhypertensive-type-2-diabetes-patients-in-ghana
#1
Kwame Yeboah, Daniel A Antwi, Ben Gyan
Background. Increased arterial stiffness is an independent cardiovascular risk factor in diabetes patients and general population. However, the contribution of diabetes to arterial stiffness is often masked by coexistent obesity and hypertension. In this study, we assessed arterial stiffness in nonhypertensive, nonobese type 2 diabetes (T2DM) patients in Ghana. Methods. In case-control design, 166 nonhypertensive, nonobese participants, comprising 96 T2DM patients and 70 nondiabetes controls, were recruited...
2016: International Journal of Endocrinology
https://www.readbyqxmd.com/read/27754115/os-23-02-the-role-of-complement-c5a-mediated-placental-dysfunction-in-the-onset-of-preeclampsia
#2
Yu Ma, Cheng-Chao Ruan, Yu Zhang, Qian Ge, Qi-Hong Wu, Ling-Ran Kong, Ping-Jin Gao
OBJECTIVE: Women with preeclampsia (PE) display excessive activation of complement system. However, little is known about the detailed cellular and molecular mechanism of complement activation in the development of PE. Here, we hypothesized that whether complement C5a contributes to the onset of PE through its effect on trophoblasts. DESIGN AND METHOD: In this study, 23 women with established PE and 32 normotensive women were recruited. At entry, peripheral and central blood pressure and pulse wave velocity (PWV) were performed...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27643042/os-23-02-the-role-of-complement-c5a-mediated-placental-dysfunction-in-the-onset-of-preeclampsia
#3
Yu Ma, Cheng-Chao Ruan, Yu Zhang, Qian Ge, Qi-Hong Wu, Ling-Ran Kong, Ping-Jin Gao
OBJECTIVE: Women with preeclampsia (PE) display excessive activation of complement system. However, little is known about the detailed cellular and molecular mechanism of complement activation in the development of PE. Here, we hypothesized that whether complement C5a contributes to the onset of PE through its effect on trophoblasts. DESIGN AND METHOD: In this study, 23 women with established PE and 32 normotensive women were recruited. At entry, peripheral and central blood pressure and pulse wave velocity (PWV) were performed...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27612397/assessment-of-arterial-stiffness-in-patients-with-metabolic-syndrome-in-ecuador-a-cross-sectional-study
#4
Carlos A Peñaherrera, Ruben Peñaherrera, Maria C Duarte, Ernesto Peñaherrera
BACKGROUND: Metabolic syndrome increases cardiovascular risk, and causes damage to the vascular wall. Through this mechanism, it might increase arterial rigidity, leading to further complications and heart strain. The use of a device that measures arterial rigidity can help determine if metabolic syndrome is related to a higher vascular stiffness and changes in estimated arterial age. METHODOLOGY: Cross-sectional study at Luis Vernaza hospital of Guayaquil, Ecuador...
September 5, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/27558210/influence-of-low-and-normal-appendicular-lean-mass-on-central-blood-pressure-and-wave-reflection-responses-to-muscle-metaboreflex-activation-in-postmenopausal-women
#5
LETTER
Arturo Figueroa, Stacey Alvarez-Alvarado, Salvador J Jaime, Sarah A Johnson, Jeremiah C Campbell, Rafaela G Feresin, Marcus L Elam, Negin Navaei, Shirin Pourafshar, Bahram H Arjmandi
Sarcopenia, defined by reduced appendicular skeletal muscle mass (ASM)/height(2) (ASMI), is associated with increased arterial stiffness (brachial-ankle pulse wave velocity, baPWV) and wave reflection (augmentation index, AIx). Blood pressure (BP) responses to metaboreflex activation (post-exercise muscle ischemia, PEMI) are exaggerated in older prehypertensives and hypertensives. We examined peripheral and aortic haemodynamics at rest and during PEMI in postmenopausal women with low-ASMI and normal-ASMI. Resting radial AIx and baPWV as well as brachial and aortic systolic BP, pulse pressure, systolic time index, and subendocardial viability ratio (SEVR) responses to PEMI were greater in women with low-ASMI than normal-ASMI...
December 2016: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/27528063/dietary-flaxseed-reduces-central-aortic-blood-pressure-without-cardiac-involvement-but-through-changes-in-plasma-oxylipins
#6
Stephanie P B Caligiuri, Delfin Rodriguez-Leyva, Harold M Aukema, Amir Ravandi, Wendy Weighell, Randolph Guzman, Grant N Pierce
UNLABELLED: In the year-long FlaxPAD clinical trial (Flaxseed for Peripheral Artery Disease), dietary flaxseed generated a powerful reduction in brachial systolic and diastolic blood pressure in patients with peripheral artery disease. Oxylipins were implicated as potential mechanistic mediators. However, the ability of flaxseed to impact central aortic hypertension, arterial stiffness, or cardiac performance was not investigated. Additionally, the relationship between central blood pressure (cBP) and oxylipins was not elucidated...
October 2016: Hypertension
https://www.readbyqxmd.com/read/27509187/the-effect-of-high-dose-cholecalciferol-on-arterial-stiffness-and-peripheral-and-central-blood-pressure-in-healthy-humans-a-randomized-controlled-trial
#7
Iain Bressendorff, Lisbet Brandi, Morten Schou, Birgitte Nygaard, Niels Erik Frandsen, Knud Rasmussen, Lars Ødum, Ove Vyff Østergaard, Ditte Hansen
BACKGROUND: Low levels of serum 25-hydroxy vitamin D are associated with increased arterial stiffness and hypertension. Supplementation with vitamin D precursors has been proposed as a treatment option for these conditions. We examined the effect of oral cholecalciferol on arterial stiffness and blood pressure in healthy normotensive adults. METHODS: 40 healthy adults were randomised in this double-blinded study to either oral cholecalciferol 3000 IU/day or matching placebo and were followed for 16 weeks to examine any effects on pulse wave velocity (PWV), augmentation index (AIx), peripheral and central blood pressure and 24-hour ambulatory blood pressure...
2016: PloS One
https://www.readbyqxmd.com/read/27508764/-op-6a-01-renalase-in-children-with-glomerular-kidney-diseases
#8
P Skrzypczyk, M Panczyk-Tomaszewska, J Przychodzien, M Mizerska-Wasiak, E Kuzma-Mroczkowska, E Gorska, A Stelmaszczyk-Emmel
OBJECTIVE: Renalase is a protein produced mainly by kidneys. Renalase inactivates circulating catecholamines catalyzing process of their oxidation. Studies in adults with kidney disease suggest that renalase may play a role in pathogenesis of hypertension and target organ damage. The aim of the study was to assess level of renalase in children with glomerular kidney diseases and to find the relation between renalase level and clinical parameters in this group of patients. DESIGN AND METHOD: In 78 children (47 M, 31F) aged from 3...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508592/-op-lb03-03-the-relationship-between-diastolic-function-and-central-hemodynamics-in-diabetic-hypertensive-patients
#9
D Agnoletti, A Lieber, F Valbusa, G Arcaro, M E Safar, J Blacher
OBJECTIVE: Diabetic hypertensives patients present different hemodynamic pattern than only hypertensive patients. We aimed to investigate the relationship between the diastolic function and the pulse pressure amplification (PPA), an index combining both arterial stiffness and wave reflexion, in diabetic hypertensives subjects compared to hypertensive subjects.(Figure is included in full-text article.) DESIGN AND METHOD: : We examined 123 patients admitted to the one day hospital of the Hotel-Dieu Hospital (Paris, France) for cardiovascular risk assessment...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508591/-op-lb03-02-non-invasive-hemodynamic-monitoring-in-uncontrolled-hypertensive-patients-effect-on-arterial-stiffness-and-central-blood-pressure-the-beauty-study
#10
P Boutouyrie, F Elmula, P Rebora, A Talvik, S Salerno, E Miszkowska-Nagorna, X Liuc, T Comotti, A Larstorp, M Rostrup, E Qwierblewska, M Valsecchi, S E Kjeldsen, M Viigimaa, K Narkiewicz, G Parati, S Laurent
OBJECTIVE: In the BEAUTY study we investigated whether utilizing non-invasive monitoring of hemodynamic parameters by thoracic impedance plethysmography (IHM) combined with a drug selection algorithm (DSA) compared to conventional drug selection may improve uncontrolled hypertension in European Hypertension Excellence Centres. Although the results of the BEAUTY study on ABPM were neutral (J Hypertens 2015), we investigated whether IHM-DSA could favourably influence central BP and arterial stiffness...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27401535/estimated-aortic-blood-pressure-based-on-radial-artery-tonometry-underestimates-directly-measured-aortic-blood-pressure-in-patients-with%C3%A2-advancing-chronic-kidney-disease-staging-and%C3%A2-increasing-arterial-stiffness
#11
Rasmus K Carlsen, Christian D Peters, Dinah S Khatir, Esben Laugesen, Hans Erik Bøtker, Simon Winther, Niels H Buus
Central blood pressure (BP) can be assessed noninvasively based on radial tonometry and may potentially be a better predictor of clinical outcome than brachial BP. However, the validity of noninvasively obtained estimates has never been examined in patients with chronic kidney disease (CKD). Here we compared invasive aortic systolic BP (SBP) with estimated central SBP obtained by radial artery tonometry and examined the influence of renal function and arterial stiffness on this relationship. We evaluated 83 patients with stage 3 to 5 CKD (mean estimated glomerular filtration rate [eGFR] 30 ml/min/1...
October 2016: Kidney International
https://www.readbyqxmd.com/read/27392510/long-term-effects-of-radiotherapy-on-arterial-stiffness-in-breast-cancer-women
#12
Paola Vallerio, Laura Sarno, Miriam Stucchi, Francesco Musca, Francesca Casadei, Alessandro Maloberti, Chiara Lestuzzi, Giuseppe Mancia, Antonella Moreo, Mauro Palazzi, Cristina Giannattasio
Radiotherapy for breast cancer may expose heart and vessels to late radiation-induced complications. Although recent technical progress in radiation therapy (RT) has been associated with drastic reduction in cardiovascular (CV) mortality, the prolonged life expectancy of patients with cancer requires CV evaluation for many years. The aim of our study was to evaluate local changes in vascular and cardiac function because of previous breast RT. We enrolled 43 patients treated with RT 15 years ago for breast cancer...
September 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27362026/associations-between-muscle-quality-arterial-stiffness-and-central-blood-pressures-in-men-3660-board-99-june-4-9-30-am-11-00-am
#13
Robert Thiebaud, Christopher Fahs, Takashi Abe, Jeremy Loenneke, Lindy Rossow, Debra Bemben, Michael Bemben
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27362020/high-intensity-interval-exercise-acutely-reduces-central-blood-pressure-and-peripheral-arterial-stiffness-3654-board-93-june-4-9-30-am-11-00-am
#14
Matthew Harber, Erika Ivey, Emily Snyder, Kelsey Arvin, Josiah Furrow, Erik Hayes
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27338467/effect-of-improving-dietary-quality-on-arterial-stiffness-in-subjects-with-type-1-and-type-2-diabetes-a-12-months-randomised-controlled-trial
#15
Kristina S Petersen, Peter M Clifton, Natalie Lister, Jennifer B Keogh
People with diabetes have accelerated arterial stiffening. The aim of this study was to determine the effect of increasing fruit, vegetable and dairy intake for 12 months on carotid femoral pulse wave velocity (cfPWV), augmentation index (AIx), and central blood pressure (cBP), compared to a usual diet control, in people with type 1 and type 2 diabetes. In a 12 months randomised controlled trial, cfPWV, AIx and cBP were measured every 3 months. The intervention group received dietary counselling to increase consumption of fruit (+1 serving/day; 150 g/day), vegetables (+2 servings/day; 150 g/day) and dairy (+1 serving/day; 200-250 g/day) at baseline, 1, 3, 6 and 9 months...
2016: Nutrients
https://www.readbyqxmd.com/read/27264506/arterial-stiffness-central-blood-pressures-wave-reflections-and-acute-hypertensive-response-in-stroke
#16
J Auer, T Weber
No abstract text is available yet for this article.
August 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27197683/effects-of-smoking-on-central-blood-pressure-and-pressure-amplification-in-hypertension-of-the-young
#17
Francesca Saladini, Elisabetta Benetti, Claudio Fania, Lucio Mos, Edoardo Casiglia, Paolo Palatini
The aim of this study was to investigate the effect of cigarette smoking on peripheral and central blood pressure (BP) in a group of young stage I hypertensives. A total of 344 untreated subjects from the HARVEST study were examined (mean age 37±10 years). Patients were divided into three groups based on smoking status: non-smokers, light smokers (⩽5 cigarettes/day) and moderate-to-heavy smokers (>5 cigarettes/day); and into three groups by age: 18-29, 30-39 and ⩾40 years. Central BP measurements and augmentation index (AIx) were calculated from brachial pressure waveform, with applanation tonometry, by means of the Specaway DAT System plus a Millar tonometer...
October 2016: Vascular Medicine
https://www.readbyqxmd.com/read/27136311/arterial-stiffness-and-medial-temporal-lobe-atrophy-in-elders-with-memory-disorders
#18
Matthieu Lilamand, Jean-Sébastien Vidal, Matthieu Plichart, Laura W De Jong, Emmanuelle Duron, Olivier Hanon
OBJECTIVES: Hypertension is a risk factor for cognitive impairment and dementia. Arterial stiffness could be involved in the mechanisms of vascular cognitive impairment and in Alzheimer's disease. We examined the association between arterial stiffness, assessed by carotid-femoral pulse wave velocity (PWV), and medial temporal lobe (MTL) atrophy, a biomarker of Alzheimer's disease. METHODS: Elderly community-dwelling study participants (n = 149) with memory complaints were diagnosed with Alzheimer's disease (n = 62) or mild cognitive impairment (n = 87) at a memory clinic...
July 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27120329/effects-of-chronic-carotid-baroreceptor-activation-on-arterial-stiffness-in-severe-heart-failure
#19
Edoardo Gronda, GianMaria Brambilla, Gino Seravalle, Alessandro Maloberti, Matteo Cairo, Giuseppe Costantino, Eric Lovett, Emilio Vanoli, Giuseppe Mancia, Guido Grassi
BACKGROUND: Heart failure with reduced ejection fraction (HFrEF) is characterized by activation of the sympathetic nervous system and increased arterial stiffness, leading to an impaired ventricular-vascular coupling. Baroreflex activation therapy (BAT) has been shown to reduce muscle sympathetic nerve activity (MSNA) and improve clinical status of patients with HFrEF. The purpose of this investigation was to determine the effects of BAT on arterial stiffness in HFrEF. METHODS AND RESULTS: MSNA, clinical variables, and parameters of central blood pressure (BP) and arterial stiffness were collected in 18 NYHA Class III HFrEF patients, nine receiving BAT and nine continuing with optimal medical management alone...
October 2016: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/27026087/effects-of-transcutaneous-electrical-nerve-stimulation-tens-on-arterial-stiffness-and-blood-pressure-in-resistant-hypertensive-individuals-study-protocol-for-a-randomized-controlled-trial
#20
José Fernando Vilela-Martin, Luiz Tadeu Giollo-Junior, Gaspar Rogério Chiappa, Gerson Cipriano-Junior, Paulo José Cardoso Vieira, Fábio dos Santos Ricardi, Manoel Ildefonso Paz-Landim, Days Oliveira de Andrade, Elizabeth do Espírito Santo Cestário, Luciana Neves Cosenso-Martin, Juan Carlos Yugar-Toledo, José Paulo Cipullo
BACKGROUND: Resistant hypertension (RH) treatment requires an adequate and intense therapeutic approach. However, the results are not always satisfactory despite intensive treatment. Of the different pathophysiological mechanisms involved in the pathogenesis of RH, sympathetic overstimulation and therapies that block the sympathetic system have been widely studied. These approaches, however, are invasive and expensive. Another possible approach is by transcutaneous electrical nerve stimulation (TENS), a noninvasive method that modulates activity by using low-frequency transcutaneous electrical stimulation to inhibit primary afferent pathways...
2016: Trials
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