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https://www.readbyqxmd.com/read/28623665/position-paper-on-olfactory-dysfunction
#1
T Hummel, K L Whitcroft, P Andrews, A Altundag, C Cinghi, R M Costanzo, M Damm, J Frasnelli, H Gudziol, N Gupta, A Haehner, E Holbrook, S C Hong, D Hornung, K B Hüttenbrink, R Kamel, M Kobayashi, I Konstantinidis, B N Landis, D A Leopold, A Macchi, T Miwa, R Moesges, J Mullol, C A Mueller, G Ottaviano, G C Passali, C Philpott, J M Pinto, V J Ramakrishnan, P Rombaux, Y Roth, R A Schlosser, B Shu, G Soler, P Stjärne, B A Stuck, J Vodicka, A Welge-Luessen
BACKGROUND: Olfactory dysfunction is an increasingly recognised condition, associated with reduced quality of life and major health outcomes such as neurodegeneration and death. However, translational research in this field is limited by heterogeneity in methodological approach, including definitions of impairment, improvement and appropriate assessment techniques. Accordingly, effective treatments for smell loss are limited. In an effort to encourage high quality and comparable work in this field, among others, we propose the following ideas and recommendations...
June 17, 2017: Rhinology
https://www.readbyqxmd.com/read/28623043/nasal-airway-evaluation-in-obstructive-sleep-apnoea-patients-volumetric-tomography-and-endoscopic-findings
#2
M M Rodrigues, M F R Gabrielli, O A Garcia Junior, V A Pereira Filho, L A Passeri
Obstructive sleep apnoea (OSA) results from the recurrent collapse of the upper airway during sleep. Nasal abnormalities influence the stability of the pharynx. The aim of this study was to evaluate the volumetric and anatomical changes of the nasal cavity in patients with OSA. The Nasal Obstruction Symptom Evaluation (NOSE) scale was used to grade nasal obstruction. Sleep-related breathing disorders were evaluated by polysomnography. The nasal airway volume was obtained from computed tomography scans through volumetric reconstruction of the nasal airway...
June 13, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28621024/the-validity-of-nasal-endoscopy-in-patients-with-chronic-rhinosinusitis-an-interrater-agreement-study
#3
K L Larsen, B Lange, P Darling, G Jørgensen, A D Kjeldsen
OBJECTIVES: Nasal endoscopy is a cornerstone in diagnosing sinonasal disease but different raters might generate different results using the technique. Our study aims to evaluate the agreement between multiple raters to assess the validity of nasal endoscopy. DESIGN/PARTICIPANTS: Three independent and blinded raters evaluated 28 patients (56 nasal cavities) diagnosed with chronic rhinosinusitis according to the European Position Paper on Rhinosinusitis and Nasal Polyps...
June 16, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28620574/complications-of-advanced-kadish-stage-esthesioneuroblastoma-single-institution-experience-and-literature-review
#4
Sheri K Palejwala, Saurabh Sharma, Christopher H Le, Eugene Chang, Michael Lemole
INTRODUCTION: In esthesioneuroblastoma, greater disease extent and Kadish staging correlate with greater recurrence, complications, and mortality. These advanced stage malignancies require extensive resections and aggressive adjuvant therapy. This increases the risk of complications such as cerebrospinal fluid leak, neurologic deficits, and osteomyelitis. We present our case series and then analyze the literature to ascertain whether advanced stage tumors corresponds to greater rates of complications...
May 12, 2017: Curēus
https://www.readbyqxmd.com/read/28616054/an-investigation-on-non-invasive-fungal-sinusitis-molecular-identification-of-etiologic-agents
#5
Abdolrasoul Mohammadi, Seyed Mostafa Hashemi, Sayed Hamidreza Abtahi, Seyed Mohammad Lajevardi, Sahar Kianipour, Rasoul Mohammadi
BACKGROUND: Fungal sinusitis is increasing worldwide in the past two decades. It is divided into two types including invasive and noninvasive. Noninvasive types contain allergic fungal sinusitis (AFS) and fungus ball. AFS is a hypersensitivity reaction to fungal allergens in the mucosa of the sinonasal tract in atopic individuals. The fungus ball is a different type of noninvasive fungal rhinosinusitis which is delineated as an accumulation of debris and fungal elements inside a paranasal sinus...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28611569/bacterial-ulcerative-esophagitis-in-an-immunocompetent-patient
#6
Jung A Shin, Young Bae Lee, In Cheol Yoon, Hyeon Ju Jeong, Taejung Kwon, Hong Sub Lee
Bacterial esophagitis is a very rare condition usually occurring in patients with immunosuppression. To our best knowledge, bacterial esophagitis without underlying immunosuppressive disease has not been reported. We report an immunocompetent patient with bacterial esophagitis caused by B-hemolytic Streptococcus which resulted in an esophageal stricture. A 68-year-old female was admitted for odynophagia which had developed several days before. Upper endoscopy revealed extensive ulceration covered by whitish exudates with submucosal edema at the proximal esophagus...
January 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28609261/nasopharyngeal-carcinoma-diagnostic-challenge-in-a-nonendemic-setting-our-experience-with-101-patients
#7
Kevin H Wang, Stephanie A Austin, Sonia H Chen, David C Sonne, Deepak Gurushanthaiah
INTRODUCTION: We studied the presenting symptoms, time intervals, and workup involved in the diagnosis of nasopharyngeal carcinoma in an integrated health care system. METHODS: A retrospective chart review of all patients with a nasopharyngeal carcinoma diagnosis between 2007 and 2010 at Kaiser Permanente Northern California. Main outcome measures included diagnostic time intervals, presenting symptoms, diagnostic accuracy of nasal endoscopy, imaging, and diagnosis at first otolaryngologist (Oto-HNS) visit...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28608749/polypoid-change-of-the-middle-turbinate-and-paranasal-sinus-polyposis-are-distinct-entities
#8
Jacob P Brunner, Basit A Jawad, Edward D McCoul
Objectives Polypoid change of the middle turbinate (PCMT) is a finding on intranasal examination whose significance is not well understood. We present a comparison of the clinical characteristics of PCMT with paranasal sinus polyposis (PSP), a common condition with potentially similar appearance. Study Design Parallel case series. Setting Tertiary rhinology clinic. Subjects and Methods Data were prospectively compiled from consecutive patients during a 12-month period with either PSP arising from the middle meatus or PCMT limited to the middle turbinate as identified on nasal endoscopy...
June 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28583236/complete-response-of-skull-base-inverted-papilloma-to-chemotherapy-case-report
#9
Edward C Kuan, John W Frederick, Miguel F Palma Diaz, Dean W Lim, Jeffrey D Suh
BACKGROUND: Inverted papilloma (IP) is the most common benign sinonasal neoplasm. Endoscopic techniques, improved understanding of pathophysiology, and novel surgical approaches have allowed rhinologists to treat IPs more effectively, with surgery being the mainstay of therapy. Frontal sinus IP poses a challenge for surgical therapy due to complex anatomy and potentially difficult surgical access. OBJECTIVES: We reported a unique case of a massive frontal sinus IP that presented with intracranial and orbital extension, with near resolution after chemotherapy...
June 1, 2017: Allergy & Rhinology
https://www.readbyqxmd.com/read/28579581/a-nasal-osteoma-with-an-acute-course-in-a-japanese-black-heifer
#10
Reiichiro Sato, Yumi Une, Hiroo Madarame, Hyougo Hanami, Eiichi Kanai, Hironobu Murakami, Atsushi Tsukamoto, Takehito Suzuki, Hideharu Ochiai, Masato Kikuchi, Hidekazu Tanaka, Ken Onda
A 14-month-old Japanese Black heifer presented with unilateral epistaxis and mild swelling of the right face. Radiography revealed a mass with increased radiopacity on the right side of the nasal bridge, extending to the left side. Intranasal endoscopy confirmed a large tumor-like structure protruding into the nasal cavity. Following euthanasia, cranial computed tomography (CT) was performed, revealing a tumor 24.3 × 17.5 × 14.8 cm in size. The tumor occupied the entire right nasal cavity and the frontal and sphenoid sinuses...
June 2, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28578115/2d-hd-versus-3d-endoscopy-in-endonasal-skull-base-surgery-a-comparative-pre-clinical-study
#11
Vittorio Rampinelli, Francesco Doglietto, Davide Mattavelli, Jimmy Qiu, Elena Raffetti, Alberto Schreiber, Andrea Bolzoni Villaret, Walter Kucharczyk, Francesco Donato, Marco Maria Fontanella, Piero Nicolai
BACKGROUND: Three-dimensional (3D) endoscopy has been recently introduced in endonasal skull base surgery. Only a relatively limited number of studies have compared it to two-dimensional, high definition (2D-HD) technology. OBJECTIVE: To analyze, in a preclinical setting for endonasal endoscopic surgery, surgical maneuverability comparing 2D-HD and 3D endoscopy. METHODS: A group of 68 volunteers, both novice and experienced surgeons, were asked to perform two tasks, namely simulating grasping and dissection surgical maneuvers, in a model of the nasal cavities...
May 31, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28576524/influence-of-nasal-septum-deformity-on-nasal-obstruction-disease-severity-and-medical-treatment-response-among-children-and-adolescents-with-persistent-allergic-rhinitis
#12
Franklin Mariño-Sánchez, Meritxell Valls-Mateus, Paulina Cardenas-Escalante, Oliver Haag, Karen Ruiz-Echevarría, Rosa Jiménez-Feijoo, Jaime Lozano-Blasco, María T Giner-Muñoz, Ana M Plaza-Martin, Joaquim Mullol
OBJECTIVE: To evaluate the impact of different types of nasal septum deformity (NSD) on nasal obstruction, rhinitis severity and response to medical treatment among pediatric persistent allergic rhinitis (PER) patients. METHODS: In a prospective, real-life study, 150 children and adolescents (mean age 13 ± 2.8 years, females 32.6%) diagnosed with PER according to ARIA guidelines were assessed by nasal endoscopy for NSD according to Mladina's classification, their response to medical treatment (intranasal steroids and antihistamines or antileucotriens), the presence of comorbidities, rhinitis severity (modified-ARIA criterion) and nasal obstruction visual analog scale score (VAS)...
April 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28574642/delivering-irrigation-to-the-anterior-ethmoid-region-evaluation-of-a-lacrimal-diversion-device-in-a-cadaver-model
#13
Bobby A Tajudeen, Sanjay Gupta, Brian Willoughby, David W Kennedy
BACKGROUND: Topical solutions to the sinus cavity are primarily administered via a transnasal route with inherent limitations of distribution. Here we describe an alternate method of sinus access via lacrimal sinus diversion using a novel lacrimal diversion device (LDD). METHODS: A cadaveric study was performed using 12 disarticulated fresh heads. The LDD was implanted in 23 sides meeting insertion criteria. Time to placement was recorded and patency was assessed via nasal endoscopy...
June 2, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28566046/are-all-manikins-created-equal-a-pilot-study-of-simulator-upper-airway-anatomic-fidelity
#14
Jennifer A Woo, Sonya Malekzadeh, Kelly M Malloy, Ellen S Deutsch
This study evaluates the anatomic fidelity of several commercially available pediatric and adult manikins, including airway task trainers, which could be used in aerodigestive procedure training. Twenty-three experienced otolaryngologists assessed the aerodigestive anatomy of 5 adult and 5 pediatric manikins in a passive state, using rigid and flexible endoscopy. Anatomic fidelity was rated on a 5-point scale for the following: nasal cavity, nasopharynx, oral cavity, oropharynx, larynx, trachea, esophagus, and neck...
June 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28558455/-effect-of-intranasal-excision-on-nasal-vestibular-cyst-under-nasal-endoscopy
#15
K F Hao, Z H Yan, S D Tao
Objective: To observe the clinical effects of intranasal excision on nasal vestibular cyst under nasal endoscopy. Methods: Forty-two cases of nasal vestibular cyst diagnosed in the Department of Otorhinolaryngology Head and Neck Surgery, Tianjin Third Central Hospital between Feb. 2011 and Jan. 2016 were treated by intranasal excision under nasal endoscope. Results: All the 42 patients were cured without any complication. The rate of complete stripping was 78.6% (33/42), with operating time of (21.31±4.04) min and bleeding amount of (10...
May 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28558147/safety-and-efficacy-of-a-bioabsorbable-fluticasone-propionate-eluting-sinus-dressing-in-postoperative-management-of-endoscopic-sinus-surgery-a-randomized-clinical-trial
#16
Gwijde F J P M Adriaensen, Keng-Hua Lim, Wytske J Fokkens
BACKGROUND: Postoperative wound healing after endoscopic sinus surgery (ESS) in patients with chronic rhinosinusitis (CRS) is an important factor in procedural success. Local steroids and separation of opposing mucosa are commonly implemented to optimize healing. A bioabsorbable, fluticasone propionate (FP)-eluting implant, SinuBand FP, was assessed for its safety and efficacy when used in patients with CRS and nasal polyps, who were indicated for ESS including bilateral anterior and posterior ethmoidectomy...
May 30, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28542331/the-feasibility-of-endoscopy-ct-image-registration-in-the-head-and-neck-without-prospective-endoscope-tracking
#17
W Scott Ingram, Jinzhong Yang, Beth M Beadle, Richard Wendt, Arvind Rao, Xin A Wang, Laurence E Court
PURPOSE: Endoscopic examinations are frequently-used procedures for patients with head and neck cancer undergoing radiotherapy, but radiation treatment plans are created on computed tomography (CT) scans. Image registration between endoscopic video and CT could be used to improve treatment planning and analysis of radiation-related normal tissue toxicity. The purpose of this study was to explore the feasibility of endoscopy-CT image registration without prospective physical tracking of the endoscope during the examination...
2017: PloS One
https://www.readbyqxmd.com/read/28540613/oral-capnography-is-more-effective-than-nasal-capnography-during-sedative-upper-gastrointestinal-endoscopy
#18
Wei-Nung Teng, Chien-Kun Ting, Yu-Tzu Wang, Ming-Chih Hou, Mei-Yung Tsou, Huihua Chiang, Chun-Li Lin
The role of capnography in esophagogastroduodenoscopy (EGD) is controversial. Simultaneous supplemental oxygen, position of patient, open mouth breathing pattern, and anatomy of the oral and nasal cavity can influence capnography accuracy. This study first measured capnographic data via the nasal or oral cavity during sedated EGD. Secondly, we investigated the influence of supplementary oxygen through the oral cavity on the capnographic reading. Patients with ASA class I or II status admitted for routine EGD exams were enrolled...
May 24, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28533859/-a-particular-type-of-cicatricial-pemphigoid-with-unique-iga-deposit
#19
Amina Aounallah, Mariem Jrad, Mehdi Ksiaa, Sana Mokni, Wafa Saidi, Lobna Boussofara, Badreddine Sriha, Mohamed Denguezli, Najet Ghariani, Colandane Belajouza, Rafia Nouira
Cicatricial Pemphigoid is a subepithelial bullous dermatosis which essentially involves the mucous membranes with cicatricial evolution We report the case of a 66-year old patient hospitalized with erosive gingivitis associated with dysphagia, dyspnea and blurred vision. Dermatologic examination showed erosive lesions involving the palate and the pharynx. Ophthalmologic examination showed symblepharons, ectropion and bilateral cataract. Gingival biopsy revealed a necrotic detachment of the buccal epithelium...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28526278/biotherapeutics-in-chronic-rhinosinusitis-with-and-without-nasal-polyps
#20
Claus Bachert, Philippe Gevaert, Peter Hellings
In western countries, 85% of chronic rhinosinusitis with nasal polyp disease reveals a type 2 inflammatory pattern with expression of IL-4, -5, and -13 as well as increased concentrations of IgE, whereas chronic rhinosinusitis without nasal polyps merely expresses these biomarkers. The degree of type 2 inflammation furthermore is associated with disease severity, asthma comorbidity, and recurrence of disease after surgery. Therefore, these biomarkers also form the targets for innovative therapeutic approaches such as monoclonal antibodies directed against IgE, IL-5, and IL-4 receptor alpha, blocking the activity of IL-4 and -13...
May 16, 2017: Journal of Allergy and Clinical Immunology in Practice
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