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https://www.readbyqxmd.com/read/29336292/use-of-intraoperative-negative-margins-reduces-inverted-papilloma-recurrence
#1
Amar Miglani, Joseph M Hoxworth, Matthew A Zarka, Devyani Lal
BACKGROUND: Recurrence of inverted papilloma (IP) is a problem in 12-17% of tumors. Controversy exists regarding benefits of intraoperative frozen section histopathology (IFSH) for IP resection; however, to our knowledge, no study has specifically investigated this. IFSH for IP resection is the standard of care in our practice. We, therefore, reviewed our outcomes of using IFSH for IP resection. A secondary goal was to assess the reliability of IFSH. METHODS: Patients with IP who underwent surgical resection (2010-2016) with minimum 9-month follow-up were included...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29336287/endoscopically-assisted-crawford-tube-placement-results-in-shorter-general-anesthesia-times-in-pediatric-patients
#2
Mitchell R Dobberpuhl, Peter J Timoney, Brett T Comer
BACKGROUND: Crawford tube placement is commonly used to achieve patency of nasolacrimal ducts for epiphora secondary to nasolacrimal duct obstruction. The nasal passages of pediatric patients are narrower than adults, and the result is a relatively higher risk of intranasal complications (e.g., synechiae, bleeding) with Crawford tube placement. There is evidence that general anesthesia may negatively affect the neurocognitive function and behavioral development of children, which prompts efforts to decrease operation times for potential health benefits and also potentially to reduce health care costs...
January 1, 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29334430/preclinical-therapeutic-efficacy-of-the-ciprofloxacin-eluting-sinus-stent-for-pseudomonas-aeruginosa-sinusitis
#3
Do-Yeon Cho, Dong-Jin Lim, Calvin Mackey, Daniel Skinner, Christopher Weeks, Gobind S Gill, Robert W Hergenrother, William E Swords, Bradford A Woodworth
BACKGROUND: The ciprofloxacin-coated sinus stent (CSS) has unique therapeutic potential to deliver antibiotics to the sinuses. The objective of this study is to evaluate the efficacy of the CSS stent in eliminating Pseudomonas aeruginosa infection in a rabbit model of sinusitis. METHODS: A ciprofloxacin-eluting sinus stent was created by coating ciprofloxacin/Eudragit RS100 on biodegradable poly-D/L-lactic acid (2 mg). After analyzing in-vitro inhibition of P aeruginosa (PAO-1 strain) biofilm formation, a total of 8 stents (4 shams, 4 CSSs) were placed unilaterally in rabbit maxillary sinuses via dorsal sinusotomy after inducing infection for 1 week with PAO-1...
January 15, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29314773/55-year-old-patient-with-intranasal-mass
#4
David W Kennedy, Robert Brody
The patient is a 55 year old female who presented with a right sided intranasal mass in 2014. Surgery was recommended, but the patient cancelled the surgery. She returned three years later with a significant progression of the lesion. What is this lesion and how would you manage it? Five months after resection of the lesion, the patient returns with pulsatile clear mucus visible on nasal endoscopy in the region of the prior mass excision. What does this represent and how should we proceed at this point? Is the patient developing a meningo-encephalocele?...
January 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29283943/can-tumor-size-be-a-predictive-factor-of-olfactory-dysfunction-after-endoscopic-endonasal-trans-sphenoidal-approach
#5
Do Hyun Kim, Yong Kil Hong, Sin-Soo Jeun, Jae-Sung Park, Soo Whan Kim, Jin Hee Cho, Yong Jin Park, Jang-Won Jeong, Sung Won Kim
BACKGROUND AND OBJECTIVE: The aim of this study is to investigate the relationships between tumor size, nasal symptoms including olfactory function, and posoperative atrophic mucosal changes after the endoscopic endonasal transsphenoidal approach (EETSA). METHODS: This was a retrospective review of the medical records of 112 patients who underwent the 2 nostrils/4 hands EETSA with bilateral modified nasoseptal rescue flaps between February 2009 and January 2016...
December 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29280484/intranasal-tissue-necrosis-associated-with-opioid-abuse-case-report-and-systematic-review
#6
REVIEW
Danielle A Morrison, Sarah K Wise, John M DelGaudio, Naweed I Chowdhury, Joshua M Levy
OBJECTIVE: Opioid abuse is a common disorder affecting over 2 million Americans. Intranasal tissue necrosis is a previously described sequela of nasal opioid inhalation, with a similar presentation to invasive fungal rhinosinusitis (IFRS). The goal of this case report and systematic review is to evaluate the evidence supporting this uncommon disease, with qualitative analysis of the presentation, management and treatment outcomes. DATA SOURCES: MEDLINE, EMBASE, Google Scholar, Scopus, and Web of Science...
December 27, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29258948/delayed-coil-migration-after-treatment-of-traumatic-pseudoaneurysm
#7
Ting Wang, Changwei Zhang, Xiaodong Xie
A teenager with epistaxis after head trauma was diagnosed with pseudoaneurysm of internal carotid artery. Three years after the first aneurysm embolization, delayed coil migration was detected. Then the migrated coil was removed through nasal-endoscopy.
December 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29240302/correlation-between-sinus-and-lung-cultures-in-lung-transplant-patients-with-cystic-fibrosis
#8
Kevin J Choi, Tracy Z Cheng, Adam L Honeybrook, Alice L Gray, Laurie D Snyder, Scott M Palmer, Ralph Abi Hachem, David W Jang
BACKGROUND: Lung transplantation has revolutionized the treatment of end-stage pulmonary disease due to cystic fibrosis. However, infection of the transplanted lungs can lead to serious complications, including graft failure and death. Although many of these patients have concurrent sinusitis, it is unclear whether bacteria from the sinuses can infect the allograft. METHODS: This is a single-institution retrospective study of all patients who underwent lung transplantation for cystic fibrosis from 2005 to 2015 at Duke University Hospital...
December 14, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29238680/diagnostic-accuracy-of-nasal-endoscopy-as-compared-to-computed-tomography-in-chronic-rhinosinusitis
#9
Nitin V Deosthale, Sonali P Khadakkar, Vivek V Harkare, Priti R Dhoke, Kanchan S Dhote, Asha Jadia Soni, Ashwini B Katke
The study was done with the aims to evaluate the accuracy of nasal endoscopy as compared to computed tomography (CT) in diagnosing chronic rhinosinusitis (CRS) and to evaluate the correlation between Endoscopy Score and CT Score. It was a cross sectional study. Every consecutive, symptomatic patient of CRS who fulfilled the criteria of American Academy of Otolaryngology-Head and Neck Surgery Task Force were included in the study. Rigid diagnostic nasal endoscopy (DNE) was done and Lund-Kennedy scoring system was used...
December 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29236649/deadly-sphenoid-fungus-isolated-sphenoid-invasive-fungal-rhinosinusitis-a-case-report
#10
Jason E Gilde, Christopher C Xiao, Victoria A Epstein, Jonathan Liang
INTRODUCTION: Acute invasive fungal rhinosinusitis (AIFRS) is a potentially fatal infection, usually affecting immunocompromised patients. Isolated sphenoid sinus involvement is rare and has been reported in only a few cases. We discuss the clinical characteristics, histopathologic features, and differential diagnosis of AIFRS of the sphenoid sinus. CASE PRESENTATION: A 57-year-old man with a history of refractory non-Hodgkin lymphoma and neutropenia presented with a 1-week duration of left-sided headache and ipsilateral cheek paresthesia...
2017: Permanente Journal
https://www.readbyqxmd.com/read/29230559/increased-histopathological-yield-for-granulomatosis-with-polyangiitis-based-on-nasal-endoscopy-of-suspected-active-lesions
#11
Olga Beltrán Rodríguez-Cabo, Edgardo Reyes, Jorge Rojas-Serrano, Luis Felipe Flores-Suárez
PURPOSE: To present the results of an endoscopic and histopathologic evaluation of suspected nasal active granulomatosis with polyangiits (GPA) lesions, describe them as seen by the ENT specialist, and propose a guide for tissue sampling of the nasal cavity to improve the yield of confirmatory histology. METHODS: Randomly selected patients seen from December 1997-October 2007 had a thorough endoscopic nasal evaluation, preceded by careful cleansing of the nasal cavity...
December 11, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29227048/the-prevalence-of-eustachian-tube-dysfunction-symptoms-in-patients-with-chronic-rhinosinusitis
#12
Navarat Tangbumrungtham, Vishal S Patel, Andrew Thamboo, Zara M Patel, Jayakar V Nayak, Yifei Ma, Garret Choby, Peter H Hwang
BACKGROUND: While Eustachian tube dysfunction (ETD) is a known comorbidity of chronic rhinosinusitis (CRS), the prevalence of ETD symptoms in the CRS population is poorly understood. We sought to determine the cross-sectional prevalence of ETD in patients with CRS using the validated Eustachian Tube Dysfunction Questionnaire (ETDQ-7) and to correlate ETDQ-7 scores with 22-item Sino-Nasal Outcome Test (SNOT-22) scores, endoscopy scores, and computed tomography (CT) scores. METHODS: A total of 101 patients with confirmed CRS completed the ETDQ-7 and SNOT-22 at their initial visit to our rhinology clinic...
December 11, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29224765/pre-and-post-operative-application-of-acoustic-rhinometry-in-children-with-otitis-media-with-effusion-and-with-or-without-adenoid-hypertrophy-a-retrospective-analysis
#13
Dan Lai, Gang Qin, Junmei Pu, Lu Liu, Yiying Yang
BACKGROUND: There is no standardized scheme for preoperative evaluation of adenoid hypertrophy or a consensus on surgical indications for adenoidectomy in children with otitis media with effusion (OME), especially for young children intolerant to nasal endoscopic assessment. The aim of this study was to evaluate the efficacy and reliability of acoustic rhinometry (AR) in evaluating benefits from adenoidectomy in children with OME. METHOD: Children with OME who were scheduled for surgical intervention were reviewed and AR tests performed preoperatively and postoperatively...
December 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29204576/comparison-of-3%C3%A2-mm-versus-4%C3%A2-mm-rigid-endoscope-in-diagnostic-nasal-endoscopy
#14
Gregory S Neel, Ryan L Kau, Stephen F Bansberg, Devyani Lal
Objective: Compare nasal endoscopy with 3 mm versus conventional 4 mm rigid 30° endoscopes for visualization, patient comfort, and examiner ease. Methods: Ten adults with no previous sinus surgery underwent bilateral nasal endoscopy with both 4 mm and 3 mm endoscopes (resulting in 20 paired nasal endoscopies). Visualization, patient discomfort and examiner's difficulty were assessed with every endoscopy. Sino-nasal structures were checked on a list if visualized satisfactorily...
March 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29202870/clinical-predictors-of-chronic-rhinosinusitis-do-the-canadian-clinical-practice-guidelines-for-acute-and-chronic-rhinosinusitis-predict-ct-confirmation-of-disease
#15
Paige Moore, Brian Blakley, Eric Meen
BACKGROUND: The diagnosis of chronic rhinosinusitis (CRS) based on clinical presentation alone remains challenging. To improve the accuracy of clinical diagnosis, the Canadian Rhinosinusitis Guidelines recommend the use of specific symptom and endoscopic criteria. Our study objective was to determine whether symptom and endoscopic criteria, as defined by the Canadian Rhinosinusitis Guidelines, accurately predict CT-confirmed CRS diagnosis. METHODS: A retrospective cohort study of 126 patients who underwent CT sinuses based on clinical suspicion of possible CRS...
December 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29202566/post-operative-nebulized-sodium-hyaluronate-versus-spray-after-functional-endoscopic-sinus-surgery-for-chronic-rhinosinusitis
#16
M Casale, A Pace, A Moffa, P Vella, L Sabatino, M A Lopez, F Salvinelli
We prospectively evaluated the efficacy of nebulized Hyaluronic Acid (HA) as an adjuvant treatment to hasten the improvement of nasal respiration and to minimize patients’ discomfort in the postoperative functional endoscopic sinus surgery (FESS) for chronic rhino-sinusitis (CRS). We enrolled 33 CRS adult patients who underwent endoscopic functional sinus surgery. They were randomly assigned into two groups: Spray-Sol group (18 patients) with HA nebulized with a new nasal device named Spray-Sol and Spray group (15 patients) with a HA nebulized with a common spray...
December 4, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29195025/lack-of-additional-effects-of-long-term-low-dose-clarithromycin-combined-treatment-compared-with-topical-steroids-alone-for-chronic-rhinosinusitis-in-china-a-randomized-controlled-trial
#17
Jie Deng, Fenghong Chen, YinYan Lai, Qing Luo, Rui Xu, Chunquan Ou, Qingling Fu, Jianbo Shi
BACKGROUND: In China, clarithromycin is considered an effective treatment option for chronic rhinosinusitis (CRS) due to its unique immunopathologic characteristics. Our study's aim was to determine whether a topical steroid and clarithromycin combination is better than a single topical steroid for Chinese patients with CRS. METHODS: Patients with CRS with/without nasal polyps were included in this study and randomly assigned to a clarithromycin plus budesonide aqua nasal spray group (CLM + BUD, clarithromycin 0...
November 30, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29186722/il-33-expression-in-chronic-rhinosinusitis-with-nasal-polyps-and-its-relationship-with-clinical-severity
#18
Wei Song, Chunlei Wang, Jing Zhou, Shenghua Pan, Sen Lin
BACKGROUND: Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by epithelial inflammation and tissue eosinophilic infiltration. Interleukin-33 (IL-33) is a key inflammatory cytokine that mediates eosinophilic infiltration. OBJECTIVE: The aim of our study was to investigate the expression and role of IL-33 in eosinophilic CRS with nasal polyps (ECRSwNP) and in noneosinophilic CRS with nasal polyps (nECRSwNP), and to analyze their correlation with clinical severity...
November 30, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29174644/does-the-reduction-of-inferior-turbinate-affect-lower-airway-functions
#19
Ozlem Unsal, Mehtap Ozkahraman, Mufide Arzu Ozkarafakili, Meltem Akpinar, Arzu Yasemin Korkut, Senem Kurt Dizdar, Berna Uslu Coskun
INTRODUCTION: Although the nose and lungs are separate organs, numerous studies have reported that the entire respiratory system can be considered as a single anatomical and functional unit. The upper and lower airways affect each other either directly or through reflex mechanisms. OBJECTIVE: In this study, we aimed to evaluate the effects of the radiofrequency ablation of persistent inferior turbinate hypertrophy on nasal and pulmonary function. METHODS: Twenty-seven patients with bilateral persistent inferior turbinate hypertrophy without septal deviation were included in this study...
November 6, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29166423/exhaled-and-nasal-nitric-oxide-in-chronic-rhinosinusitis-patients-with-nasal-polyps-in-primary-care
#20
M Frendø, K Håkansson, S Schwer, A T Ravn, H Meteran, C Porsbjerg, V Backer, C von Buchwald
BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disorder associated with lower airway disease. However, only few studies of CRSwNP from outside secondary/tertiary care centres have been published. We recently reported an asthma frequency of 44% and 65% in primary and secondary care patients respectively. Therefore, we hypothesise that inflammation of the lower airways could be present in all CRSwNP patients, even without asthma. Here, we assessed the degree of lower and upper airway inflammation using exhaled and nasal nitric oxide (NO) in primary care CRSwNP patients with and without asthma...
November 23, 2017: Rhinology
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