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histamine and intolerance

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https://www.readbyqxmd.com/read/29060010/a-roic-for-mn-tpp-cl-dop-thf-polyhema-pvc-membrane-modified-n-channel-si3n4-isfet-sensitive-to-histamine
#1
N L M A Samah, Khuan Y Lee, S A Sulaiman, R Jarmin
Intolerance of histamine could lead to scombroid poisoning with fatal consequences. Current detection methods for histamine are wet laboratory techniques which employ expensive equipment that depends on skills of seasoned technicians and produces delayed test analysis result. Previous works from our group has established that ISFETs can be adapted for detecting histamine with the use of a novel membrane. However, work to integrate ISFETs with a readout interfacing circuit (ROIC) circuit to display the histamine concentration has not been reported so far...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29057915/mast-cell-involvement-in-glucose-tolerance-impairment-caused-by-chronic-mild-stress-with-sleep-disturbance
#2
Sachiko Chikahisa, Saki Harada, Noriyuki Shimizu, Tetsuya Shiuchi, Airi Otsuka, Seiji Nishino, Hiroyoshi Séi
We have developed a chronic mild stress (MS) mouse model by simply rearing mice on a wire net for 3 weeks and investigated the effects of MS on glucose homeostasis and sleep. MS mice showed impaired glucose tolerance and disturbed sleep. One-week treatment with a histamine H1 receptor antagonist (H1RA) ameliorated the glucose intolerance and improved sleep quality in MS mice. MS mice showed an increased number of mast cells in both adipose tissue and the brain. Inhibition of mast cell function ameliorated the impairment in both glucose tolerance and sleep...
October 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29046748/%C3%AE-thalassemia-minor-carbohydrate-malabsorption-and-histamine-intolerance
#3
Wolfgang J Schnedl, Michael Schenk, Sonja Lackner, Sandra J Holasek, Harald Mangge
Background: β-thalassemia minor is characterized by reduced β-haemoglobin chain synthesis and sometimes mild anaemia, although carriers of β-thalassemia minorare usually clinically asymptomatic.Nonspecific abdominal complaints may be caused by gastrointestinal carbohydrate malabsorption (lactose and fructose) and/or malabsorption of biogenic amines (histamine), or proteins (gluten). Objectives: We report on two patients with β-thalassemia minor suffering nonspecific abdominal symptoms due to a carbohydrate and histamine malabsorption...
October 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/28804811/serum-diamine-oxidase-in-pseudoallergy-in-the-pediatric-population
#4
Joanna Kacik, Barbara Wróblewska, Sławomir Lewicki, Robert Zdanowski, Bolesław Kalicki
Histamine intolerance (pseudoallergy) is a poorly investigated type of food hypersensitivity. The main enzyme responsible for histamine degradation in the extracellular matrix is diamine oxidase (DAO). Disturbances in the concentration or activity of DAO may lead to the development of clinical signs of allergy. The aim of the present work was to assess the DAO concentration, peripheral blood morphology, lymphocytes phenotyping (CD3+, CD4+, CD8+, CD19+, NK cells, NKT cells, and activated T-cells), and natural regulatory Treg (nTregs) cell population (CD4+, CD25+, CD127low, and FoxP3) in 34 pediatric patients with histamine-dependent syndromes...
August 15, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28715791/new-approach-for-the-diagnosis-of-histamine-intolerance-based-on-the-determination-of-histamine-and-methylhistamine-in-urine
#5
Oriol Comas-Basté, M Luz Latorre-Moratalla, Roberta Bernacchia, M Teresa Veciana-Nogués, M Carmen Vidal-Carou
Histamine intolerance is a disorder in the homeostasis of histamine due to a reduced intestinal degradation of this amine, mainly caused by diamine oxidase (DAO) enzyme deficiency, which provokes its accumulation in plasma and the appearance of adverse health affects. A new approach for the diagnosis of this intolerance could be the determination of histamine and its metabolites in urine. The aim of this work was to develop and validate a rapid method to determine histamine and methylhistamine in human urine by Ultra High Performance Liquid Chromatography and Fluorimetric detection (UHPLC-FL)...
October 25, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28656910/effectiveness-and-safety-of-levocetirizine-10-mg-versus-a-combination-of-levocetirizine-5-mg-and-montelukast-10-mg-in-chronic-urticaria-resistant-to-levocetirizine-5-mg-a-double-blind-randomized-controlled-trial
#6
Tushar Kanti Sarkar, Amrita Sil, Santasmita Pal, Chinmoy Ghosh, Nilay Kanti Das
BACKGROUND: Chronic urticaria is a vexing problem for patients and treating physicians alike. The EAACI/GA[2]LEN/EDF/WAO guidelines advocate an increased antihistamine dosage up to four times the standard, before adding leukotriene receptor antagonists. Patients are frequently intolerant of these higher dosages. We conducted this study to determine whether the addition of leukotriene receptor antagonists to the standard antihistamine dose was comparable to higher dosages of antihistamines alone, in terms of efficacy, safety and quality of life changes...
September 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/28624934/low-serum-diamine-oxidase-dao-activity-levels-in-patients-with-migraine
#7
Joan Izquierdo-Casas, Oriol Comas-Basté, M Luz Latorre-Moratalla, Marian Lorente-Gascón, Adriana Duelo, M Carmen Vidal-Carou, Luis Soler-Singla
Histamine intolerance is a disorder in the homeostasis of histamine due to a reduced intestinal degradation of this amine, mainly caused by a deficiency in the enzyme diamine oxidase (DAO). Among the several multi-faced symptoms associated with histamine intolerance, headache is one of the most recognized and disabling consequences. The aim of this study was to determine the prevalence of DAO deficiency in patients with a confirmed migraine diagnosis according to the current International Headache Society (IHS) and in non-migraine subjects...
June 17, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28425596/histamine-intolerance-in-chronic-urticaria
#8
R Jarisch
No abstract text is available yet for this article.
April 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28405073/benign-pancreatic-hyperenzymemia-gullo-syndrome-histamine-intolerance-and-carbohydrate-malabsorption
#9
Wolfgang J Schnedl, Dietmar Enko, Harald Mangge, Michael Schenk, Sonja Lackner, Sandra J Holasek
Benign pancreatic hyperenzymemia (Gullo syndrome) is characterized by a more than threefold increase of the pancreatic enzymes lipase and amylase in the absence of a pancreatic disease over a period of more than 1 year, with elevations and significant undulations of pancreatic enzyme serum concentrations occurring on a day-to-day basis for 5 consecutive days. Nonspecific abdominal complaints may be caused by carbohydrate and/or protein malabsorption. We report a patient with benign pancreatic hyperenzymemia with lactose and histamine malabsorption; the symptoms of gastrointestinal malabsorption were treated successfully with an individually tailored lactose- and histamine-free diet...
April 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28399090/-a-comparative-study-of-immune-and-clinical-indicators-in-radicular-and-myofascial-back-pain
#10
COMPARATIVE STUDY
A I Levashova, V S Morozova, S N Petrochenko, М А Myagkova, I A Moseikin
AIM: To compare immunochemical and clinical parameters in patients with chronic radicular and myofascial back pain. MATERIAL AND METHODS: A study included 92 patients (55 men and 37 women) with radicular pain syndrome and 97 patients (33 men and 64 women) with myofascial pain syndrome. Pain status was assessed with the differential visual analogous scale (at rest, on movement, at night and during spontaneous pain). Tensor algometry was used to measure pain intolerance thresholds at day and night...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28344921/german-guideline-for-the-management-of-adverse-reactions-to-ingested-histamine-guideline-of-the-german-society-for-allergology-and-clinical-immunology-dgaki-the-german-society-for-pediatric-allergology-and-environmental-medicine-gpa-the-german-association-of
#11
Imke Reese, Barbara Ballmer-Weber, Kirsten Beyer, Thomas Fuchs, Jörg Kleine-Tebbe, Ludger Klimek, Ute Lepp, Bodo Niggemann, Joachim Saloga, Christiane Schäfer, Thomas Werfel, Torsten Zuberbier, Margitta Worm
Adverse food reactions are far more often perceived than objectively verified. In our scientific knowledge on non-allergic adverse reactions including the so called histamine intolerance, there are large deficits. Due to the fact that this disorder is increasingly discussed in the media and the internet, more and more people suspect it to be the trigger of their symptoms. The scientific evidence to support the postulated link between ingestion of histamine and adverse reactions is limited, and a reliable laboratory test for objective diagnosis is lacking...
2017: Allergo Journal International
https://www.readbyqxmd.com/read/28261177/the-histidine-decarboxylase-gene-cluster-of-lactobacillus-parabuchneri-was-gained-by-horizontal-gene-transfer-and-is-mobile-within-the-species
#12
Daniel Wüthrich, Hélène Berthoud, Daniel Wechsler, Elisabeth Eugster, Stefan Irmler, Rémy Bruggmann
Histamine in food can cause intolerance reactions in consumers. Lactobacillus parabuchneri (L. parabuchneri) is one of the major causes of elevated histamine levels in cheese. Despite its significant economic impact and negative influence on human health, no genomic study has been published so far. We sequenced and analyzed 18 L. parabuchneri strains of which 12 were histamine positive and 6 were histamine negative. We determined the complete genome of the histamine positive strain FAM21731 with PacBio as well as Illumina and the genomes of the remaining 17 strains using the Illumina technology...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27856296/tyramine-and-histamine-risk-assessment-related-to-consumption-of-dry-fermented-sausages-by-the-spanish-population
#13
M L Latorre-Moratalla, O Comas-Basté, S Bover-Cid, M C Vidal-Carou
Tyramine and histamine are the main dietary bioactive amines related to acute adverse health effects. Dry fermented sausages can easily accumulate high levels of these hazards and are frequently consumed in Spain. The present work aims to assess the exposure to tyramine and histamine from the consumption of dry fermented sausages by the Spanish population and to assess the risk to suffer acute health effects from this exposure. A probabilistic estimation of the exposure to these hazards was derived combining probability distributions of these amines in dry fermented sausages (n = 474) and their consumption by the Spanish population...
January 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/27699780/diet-and-headache-part-1
#14
REVIEW
Vincent T Martin, Brinder Vij
BACKGROUND: The role of diet in the management of the headache patient is a controversial topic in the headache field. OBJECTIVES: To review the evidence supporting the hypothesis that specific foods or ingredients within foods and beverages trigger attacks of headache and/or migraine and to discuss the use of elimination diets in the prevention of headache disorders METHODS: This represents part 1 of a narrative review of the role of diet in the prevention of migraine and other headache disorders...
October 2016: Headache
https://www.readbyqxmd.com/read/27624921/a-popular-myth-low-histamine-diet-improves-chronic-spontaneous-urticaria-fact-or-fiction
#15
N Wagner, D Dirk, A Peveling-Oberhag, I Reese, U Rady-Pizarro, H Mitzel, P Staubach
BACKGROUND: Chronic spontaneous urticaria (CsU) is a frequent dermatological disease that might last for months or years with high impact on quality of life. Known causes are autoreactive phenomena, infections or intolerances, rarely IgE-mediated allergies. One-third of CsU patients benefit from a low-pseudoallergen diet. Additionally, it is often discussed, that reducing histamine ingestion alone might improve clinical symptoms and quality of life in CsU patients despite the uncertain role of the histamine-degrading enzyme diamine oxidase (DAO)...
April 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27590961/histamine-intolerance-and-dietary-management-a-complete-review
#16
REVIEW
I San Mauro Martin, S Brachero, E Garicano Vilar
BACKGROUND: Present in several types of food, bioactive amines are described as organic bases of low molecular weight, which constitute a potential health risk. An awareness of amine levels in foods today is therefore important in relation to food safety and patient care. This review aims to emphasise the need to unify the information on the content of biogenic amines in foods and prevent patients' misunderstanding. METHODS: Selective literature search for relevant publications in PubMed and other scientific data bases combined with further data from the World Wide Web on histamine and other amines content in foods...
September 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27524468/determinants-of-angiotensin-converting-enzyme-inhibitor-acei-intolerance-and-angioedema-in-the-uk-clinical-practice-research-datalink
#17
Seyed Hamidreza Mahmoudpour, Ekaterina Vitalievna Baranova, Patrick C Souverein, Folkert W Asselbergs, Anthonius de Boer, Anke Hilse Maitland-van der Zee
AIM: The aim of the present study was to describe the occurrence and determinants of angiotensin-converting enzyme (ACE) inhibitor (ACEI) intolerance and angioedema (AE) among patients initiating ACEI therapy in a real-world primary care population. METHODS: Two nested case-control studies were conducted in a cohort of 276 977 patients aged ≥45 years initiating ACEIs from 2007 to 2014 in the UK Clinical Practice Research Datalink (CPRD). Cases of AE occurring for the first time during ACEI therapy (n = 416) were matched with AE-free controls (n = 4335) on the duration of ACEI treatment...
December 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27438291/pitolisant-first-global-approval
#18
REVIEW
Yahiya Y Syed
Pitolisant (Wakix™) is an inverse agonist of the histamine H3 receptor that is being developed by Bioproject. Oral pitolisant is approved in the EU for the treatment of narcolepsy with or without cataplexy in adults. Pitolisant has received a Temporary Authorization of Use in France for this indication in case of treatment failure, intolerance or contraindication to currently available treatment. Pitolisant has orphan drug designation in the EU and the USA. In the pivotal HARMONY I trial, pitolisant significantly decreased excessive daytime sleepiness versus placebo in adults with narcolepsy with or without cataplexy (primary endpoint)...
September 2016: Drugs
https://www.readbyqxmd.com/read/27329741/histamine-intolerance-in-patients-with-chronic-spontaneous-urticaria
#19
F Siebenhaar, A Melde, M Magerl, T Zuberbier, M K Church, M Maurer
BACKGROUND: Histamine intolerance and pseudoallergy to foods have been suggested to be causes of chronic spontaneous urticaria (CSU) with some patients reporting exacerbation with histamine-rich foods. OBJECTIVE: The study aim was to identify the rate of histamine-intolerant CSU patients and to characterize the relevance of histamine intolerance as an underlying cause of CSU. METHODS: A cohort of 157 of moderate to severe CSU patients (UAS7 ≥ 10) was asked to provide a detailed clinical history, particularly in relation to symptom development after eating histamine-rich foods...
October 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27215624/-food-allergy-and-intolerance-distinction-definitions-and-delimitation
#20
REVIEW
Jörg Kleine-Tebbe, Anja Waßmann-Otto, Hubert Mönnikes
Immunologically mediated hypersensitivity to foods is defined as food allergy, mainly due to immunglobulins of class E (IgE) triggering immediate reactions (type I hypersensitivity) with possible involvement of mucosa, skin, airways, intestinal tract, and the vascular system. Primary food allergy is based on (early) IgE sensitization against animal (e. g., cow's milk, hen's eggs) or plant proteins (e. g. peanut, hazelnut or wheat). In the case of secondary food allergies, IgE against pollen proteins (e...
June 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
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