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Imke Rohard, Ulrike Subotic, Daniel Max Weber
INTRODUCTION: Failure to detect and treat partial or complete avulsions of the nail bed may lead to severe nail deformity that predisposes to repeat injuries and is cosmetically inacceptable. Treatment of these injuries with split-thickness nail bed grafts (STNBGs) is controversial and no pediatric series has been published. METHODS: A retrospective, single center case series of nine fingers with complex nail bed injuries that were reconstructed primarily with STNBGs was performed...
August 2012: European Journal of Pediatric Surgery
Ulrike Subotic, Imke Rohard, Daniel Max Weber, Rita Gobet, Ueli Moehrlen, Ricardo Gonzalez
OBJECTIVE: Open dismembered pyeloplasty is considered the gold standard to treat ureteropelvic junction obstruction (UPJO) in children. Laparoscopic pyeloplasty (LP) and robot-assisted pyeloplasty (RAP) are increasingly popular. Our present protocol consists of using minimally invasive techniques for all children with UPJO. Here, we report our first 40 cases operated under this protocol. PATIENTS AND METHODS: Retrospective chart review of patients who underwent LP and RAP for UPJO between 2006 and 2010 was performed...
August 2012: Journal of Pediatric Urology
I Rohard, E Schaefer, C Kampmann, M Beck, A Gal
Fabry disease is an X-chromosomal storage disorder due to loss-of-function mutations of the GLA gene encoding the lysosomal enzyme α-galactosidase A. Accumulating glycosphingolipid deposits disturb the function of various cells, in particular that of myocytes, arterial smooth-muscle cells, and vascular endothelium. Hypertrophic cardiomyopathy, for example measured by left posterior wall thickness (LPWT) of the heart, represents a major component of Fabry disease morbidity in adult patients. Endothelium-derived nitric oxide (eNO), produced by eNO synthase (eNOS), is a key regulator of vessel wall function and cardiovascular homeostasis...
December 2008: Journal of Inherited Metabolic Disease
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March 1960: Archives des Maladies de L'appareil Digestif et des Maladies de la Nutrition
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