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https://www.readbyqxmd.com/read/29239382/argentinian-geoscientist-faces-criminal-charges-over-glacier-survey
#1
Jeff Tollefson, Emiliano Rodríguez Mega
No abstract text is available yet for this article.
December 14, 2017: Nature
https://www.readbyqxmd.com/read/29239186/high-yield-fabrication-of-entangled-photon-emitters-for-hybrid-quantum-networking-using-high-temperature-droplet-epitaxy
#2
Francesco Basso Basset, Sergio Bietti, Marcus Reindl, Luca Esposito, Alexey Fedorov, Daniel Huber, Armando Rastelli, Emiliano Bonera, Rinaldo Trotta, Stefano Sanguinetti
Several semiconductor quantum dot techniques have been investigated for the generation of entangled photon pairs. Among the other techniques, droplet epitaxy enables the control of the shape, size, density, and emission wavelength of the quantum emitters. However, the fraction of the entanglement-ready quantum dots that can be fabricated with this method is still limited to around 5%, and matching the energy of the entangled photons to atomic transitions-a promising route towards quantum networking-remains an outstanding challenge...
December 14, 2017: Nano Letters
https://www.readbyqxmd.com/read/29234917/cardiovascular-and-metabolic-responses-during-indoor-climbing-and-laboratory-cycling-exercise-in-advanced-and-%C3%A3-lite-climbers
#3
Eloisa Limonta, Alfredo Brighenti, Susanna Rampichini, Emiliano Cè, Federico Schena, Fabio Esposito
PURPOSE: To validate heart rate (f H) as an effective indicator of the aerobic demands of climbing, the f H vs oxygen uptake ([Formula: see text]) relationship determined during cycling exercise and climbing on a circular climbing treadwall was compared. Possible differences in maximum aerobic characteristics between advanced and élite climbers were also assessed. METHODS: Seven advanced and six élite climbers performed a discontinuous incremental test on a cycle ergometer and a similar test on a climbing treadwall...
December 12, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29233200/first-rescue-under-the-rubble-the-medical-aid-in-the-first-hours-after-the-earthquake-in-amatrice-italy-on-august-24-2016
#4
Angelo Geremia Blasetti, Emiliano Petrucci, Vincenza Cofini, Barbara Pizzi, Paolo Scimia, Tullio Pozone, Stefano Necozione, Pierfrancesco Fusco, Franco Marinangeli
Specific Event Identifiers a. Event Type: Earthquake measuring 6.2 (SD=0.016) on the moment magnitude; b. Event Onset: August 24, 2016 - 03:36:32 CEST (01:36 UTC); c. Location of Event: Central Italy, in the town of Amatrice; d. Geographic Coordinates: latitude (DMS): 42°37'45.77″N; longitude (DMS): 13°17'18.14″E; elevation: 955 meters above sea-level; e. Dates: August 24, 2016 at 4:48 AM; f. Response Type: Medical Relief. ABSTRACT: On August 24, 2016, an earthquake hit the town of Amatrice (Italy)...
December 13, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/29226521/the-ontogeny-of-the-female-reproductive-system-in-the-parasitic-castrator-pea-crab-calyptraeotheres-garthi-implications-for-its-mating-system
#5
Emiliano H Ocampo, Tomás A Luppi, Eduardo D Spivak, Sebastian Klaus
The knowledge of the mating system of pea crabs is still fragmentary as it remains dubious whether females copulate in the juvenile and free-living 'hard' or in the obligatory symbiotic stages (adult stage 'V' or intermediate stages II to IV). To discriminate between these two possibilities, we analysed the female seminal receptacles, vagina and opercula, and the sperm content in different stages of the pea crab Calyptraeotheres garthi. Our histology and scanning electron microscopy results revealed that in the hard stage the seminal receptacle is simple without secretory epithelia, and vagina and opercula are not controlled by musculature...
December 11, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29221136/kif3a-and-il-4-are-disease-specific-biomarkers-for-psoriatic-arthritis-susceptibility
#6
Raffaella Cascella, Claudia Strafella, Michele Ragazzo, Laura Manzo, Gaetana Costanza, John Bowes, Ulrike Hüffmeier, Saverio Potenza, Federica Sangiuolo, André Reis, Anne Barton, Giuseppe Novelli, Augusto Orlandi, Emiliano Giardina
To date, the genes associated with Psoriatic Arthritis (PsA) are principally involved in inflammation, immune response and epidermal differentiation, without any information about the relationship between disease and bone metabolism genes. Our work was focused on 5q31 locus, which contains several genetic variants significantly associated with PsA. The study involved 1526 subjects (500 PsA, 426 PsV, 600 controls). The region was evaluated by selecting and genotyping the SNPs of interest by Real Time PCR and direct sequencing...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29221096/high-resolution-beam-profiling-of-x-ray-free-electron-laser-radiation-by-polymer-imprint-development
#7
Benedikt Rösner, Florian Döring, Primož R Ribič, David Gauthier, Emiliano Principi, Claudio Masciovecchio, Marco Zangrando, Joan Vila-Comamala, Giovanni De Ninno, Christian David
High resolution metrology of beam profiles is presently a major challenge at X-ray free electron lasers. We demonstrate a characterization method based on beam imprints in poly (methyl methacrylate). By immersing the imprints formed at 47.8 eV into organic solvents, the regions exposed to the beam are removed similar to resist development in grayscale lithography. This allows for extending the sensitivity of the method by more than an order of magnitude compared to the established analysis of imprints created solely by ablation...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29208951/functional-and-spatial-segregation-within-the-inferior-frontal-and-superior-temporal-cortices-during-listening-articulation-imagery-and-production-of-vowels
#8
Alessandra Cecilia Rampinini, Giacomo Handjaras, Andrea Leo, Luca Cecchetti, Emiliano Ricciardi, Giovanna Marotta, Pietro Pietrini
Classical models of language localize speech perception in the left superior temporal and production in the inferior frontal cortex. Nonetheless, neuropsychological, structural and functional studies have questioned such subdivision, suggesting an interwoven organization of the speech function within these cortices. We tested whether sub-regions within frontal and temporal speech-related areas retain specific phonological representations during both perception and production. Using functional magnetic resonance imaging and multivoxel pattern analysis, we showed functional and spatial segregation across the left fronto-temporal cortex during listening, imagery and production of vowels...
December 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29207301/percutaneous-low-dose-ct-guided-lung-biopsy-with-an-augmented-reality-navigation-system-validation-of-the-technique-on-496-suspected-lesions
#9
Eliodoro Faiella, Giulia Frauenfelder, Domiziana Santucci, Giacomo Luppi, Emiliano Schena, Bruno Beomonte Zobel, Rosario Francesco Grasso
PURPOSE: To validate a CT-navigation system during percutaneous lung biopsy (PLB). METHODS: Four hundred-ninety-six patients underwent low-dose CT-guided PLB. Lesion diameter (LD), procedural time (PT), histologic validity, lesion distance from pleural surface (DPS), needle distance travelled during procedure (DTP), complications and radiation exposure were recorded. RESULTS: Hysto-patological diagnosis was obtained in 96.2% cases. Mean PT, DPS, DTP, LD were respectively 29...
December 2, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/29206291/cranial-shape-variation-in-adult-howler-monkeys-alouatta-seniculus
#10
Luca Fiorenza, Emiliano Bruner
Howler monkeys (genus Alouatta) display a distinctive cranial architecture characterized by airorhynchy (or retroflexion of the facial skeleton on the cranial base), a small braincase, and a posteriorly oriented foramen magnum. This configuration has been associated with distinct factors including a high folivory diet, locomotion, and the presence of a specialized vocal tract characterized by large hyoid bone. However, the morphological relationships between the facial and neurocranial blocks in Alouatta have been scarcely investigated...
December 5, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/29203843/bisexuality-among-a-cohort-of-university-students-prevalence-and-psychological-distress
#11
Giacomo Ciocca, Caterina Solano, Giorgio Di Lorenzo, Erika Limoncin, Daniele Mollaioli, Eleonora Carosa, Alberto Collazzoni, Emiliano Santarnecchi, Emanuela Bianciardi, Cinzia Niolu, Alberto Siracusano, Alessandro Rossi, Emmanuele A Jannini
Sociocultural prejudices and pressures may impair the mental health of bisexual people. We aim to evaluate psychological status according to sexual orientation in a sample of Italian university students, with specific attention to bisexuality and its frequency. Among a recruited sample of 551 university students, we found the following percentages for sexual orientation: heterosexuals 96.9% (n = 534), homosexuals 1.1% (n = 6), bisexuals 2% (n = 11). The cross-sectional analysis for psychological symptoms, with the Symptoms Check List-90 Revised (SCL-90-R), revealed that bisexual subjects have statistically significant higher scores on some symptomatic scales compared to heterosexuals...
December 4, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29199391/variations-in-the-practice-of-molecular-radiotherapy-and-implementation-of-dosimetry-results-from-a-european-survey
#12
Katarina Sjögreen Gleisner, Emiliano Spezi, Pavel Solny, Pablo Minguez Gabina, Francesco Cicone, Caroline Stokke, Carlo Chiesa, Maria Paphiti, Boudewijn Brans, Mattias Sandström, Jill Tipping, Mark Konijnenberg, Glenn Flux
BACKGROUND: Currently, the implementation of dosimetry in molecular radiotherapy (MRT) is not well investigated, and in view of the Council Directive (2013/59/Euratom), there is a need to understand the current availability of dosimetry-based MRT in clinical practice and research studies. The aim of this study was to assess the current practice of MRT and dosimetry across European countries. METHODS: An electronic questionnaire was distributed to European countries...
December 4, 2017: EJNMMI Physics
https://www.readbyqxmd.com/read/29198592/can-tangier-disease-cause-male-infertility-a-case-report-and-an-overview-on-genetic-causes-of-male-infertility-and-hormonal-axis-involved
#13
Laura Stocchi, Emiliano Giardina, Luigia Varriale, Annalisa Sechi, Andrea Vagnini, Gianni Parri, Massimo Valentini, Maria Capalbo
Tangier disease is an autosomal recessive disorder caused by mutations in the ABCA1 gene and characterized by the accumulation of cholesteryl ester in various tissues and a near absence of high-density lipoprotein. The subject in this investigation was a 36-year-old Italian man with Tangier disease. He and his wife had come to the In Vitro Fertilization Unit, Pesaro Hospital (Azienda Ospedaliera Ospedali Riuniti Marche Nord) seeking help regarding fertility issues. The man was diagnosed with severe oligoasthenoteratozoospermia...
November 26, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29197628/towards-the-application-of-precision-medicine-in-age-related-macular-degeneration
#14
REVIEW
Raffaella Cascella, Claudia Strafella, Valerio Caputo, Valeria Errichiello, Stefania Zampatti, Filippo Milano, Saverio Potenza, Silvestro Mauriello, Giuseppe Novelli, Federico Ricci, Andrea Cusumano, Emiliano Giardina
The review essentially describes genetic and non-genetic variables contributing to the onset and progression of exudative Age-related Macular Degeneration (AMD) in Italian population. In particular, AMD susceptibility within Italian population is contributed to by genetic variants, accounting for 23% of disease and non-genetic variants, accounting for 10% of AMD. Our data highlighted prominent differences concerning genetic and non-genetic contributors to AMD in our cohort with respect to worldwide populations...
November 29, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/29188035/oxidative-changes-in-lipids-proteins-and-antioxidants-in-yogurt-during-the-shelf-life
#15
Anna Citta, Alessandra Folda, Valeria Scalcon, Guido Scutari, Alberto Bindoli, Marco Bellamio, Emiliano Feller, Maria Pia Rigobello
Oxidation processes in milk and yogurt during the shelf life can result in an alteration of protein and lipid constituents. Therefore, the antioxidant properties of yogurt in standard conditions of preservation were evaluated. Total phenols, free radical scavenger activity, degree of lipid peroxidation, and protein oxidation were determined in plain and skim yogurts with or without fruit puree. After production, plain, skim, plain berries, and skim berries yogurts were compared during the shelf life up to 9 weeks...
November 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/29185067/phantom-validation-of-quantitative-y-90-pet-ct-based-dosimetry-in-liver-radioembolization
#16
Marco D'Arienzo, Maria Pimpinella, Marco Capogni, Vanessa De Coste, Luca Filippi, Emiliano Spezi, Nick Patterson, Francesca Mariotti, Paolo Ferrari, Paola Chiaramida, Michael Tapner, Alexander Fischer, Timo Paulus, Roberto Pani, Giuseppe Iaccarino, Marco D'Andrea, Lidia Strigari, Oreste Bagni
BACKGROUND: PET/CT has recently been shown to be a viable alternative to traditional post-infusion imaging methods providing good quality images of 90Y-laden microspheres after selective internal radiation therapy (SIRT). In the present paper, first we assessed the quantitative accuracy of 90Y-PET using an anthropomorphic phantom provided with lungs, liver, spine, and a cylindrical homemade lesion located into the hepatic compartment. Then, we explored the accuracy of different computational approaches on dose calculation, including (I) direct Monte Carlo radiation transport using Raydose, (II) Kernel convolution using Philips Stratos, (III) local deposition algorithm, (IV) Monte Carlo technique (MCNP) considering a uniform activity distribution, and (V) MIRD (Medical Internal Radiation Dose) analytical approach...
November 28, 2017: EJNMMI Research
https://www.readbyqxmd.com/read/29184208/temporally-precise-single-cell-resolution-optogenetics
#17
Or A Shemesh, Dimitrii Tanese, Valeria Zampini, Changyang Linghu, Kiryl Piatkevich, Emiliano Ronzitti, Eirini Papagiakoumou, Edward S Boyden, Valentina Emiliani
Optogenetic control of individual neurons with high temporal precision within intact mammalian brain circuitry would enable powerful explorations of how neural circuits operate. Two-photon computer-generated holography enables precise sculpting of light and could in principle enable simultaneous illumination of many neurons in a network, with the requisite temporal precision to simulate accurate neural codes. We designed a high-efficacy soma-targeted opsin, finding that fusing the N-terminal 150 residues of kainate receptor subunit 2 (KA2) to the recently discovered high-photocurrent channelrhodopsin CoChR restricted expression of this opsin primarily to the cell body of mammalian cortical neurons...
December 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/29181702/geoepidemiology-of-primary-biliary-cholangitis-lessons-from-switzerland
#18
Benedetta Terziroli Beretta-Piccoli, Guido Stirnimann, Andreas Cerny, David Semela, Roxane Hessler, Beat Helbling, Felix Stickel, Carolina Kalid-de Bakker, Florian Bihl, Emiliano Giostra, Magdalena Filipowicz Sinnreich, Carl Oneta, Adriana Baserga, Pietro Invernizzi, Marco Carbone, Joachim Mertens
No data on primary biliary cholangitis (PBC) are available in Switzerland. We established a national patient cohort to obtain information on PBC phenotypes and disease course in Switzerland. Local databases in all university hospitals and in two large secondary centers were searched for case finding. In addition, all primary care physicians, gastroenterologists, rheumatologists, and dermatologists were invited to contribute patients from their own medical records. PBC diagnosis was centrally reviewed. Five hundred one PBC patients were identified, 474 were included in data analysis, and 449 of them were enrolled by tertiary centers...
November 27, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29177975/hepatic-safety-analysis-of-trabectedin-results-of-a-pharmacokinetic-study-with-trabectedin-in-patients-with-hepatic-impairment-and-experience-from-a-phase-3-clinical-trial
#19
Emiliano Calvo, Analia Azaro, Jordi Rodon, Luc Dirix, Manon Huizing, Francis Mark Senecal, Patricia LoRusso, Lorrin Yee, Italo Poggesi, Jan de Jong, Spyros Triantos, Youn C Park, Roland E Knoblauch, Trilok V Parekh, George D Demetri, Margaret von Mehren
Purpose Trabectedin is metabolized by the liver and has been associated with transient, noncumulative transaminase elevation. Two recent studies further characterize hepatic tolerability with trabectedin therapy: a phase 1 pharmacokinetic study (Study #1004; NCT01273493) in patients with advanced malignancies and hepatic impairment (HI), and a phase 3 study (Study #3007; NCT01343277) of trabectedin vs. dacarbazine in patients with advanced sarcomas and normal hepatic function. Methods In Study #1004, patients received a single 3-h intravenous (IV) infusion of trabectedin: control group, trabectedin 1...
November 27, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/29176403/tlr4-and-nlrp3-caspase-1-il-1%C3%AE-axis-are-not-involved-in-colon-ascendens-stent-peritonitis-casp-associated-heart-disease
#20
Maria Micaela Lopez Alarcón, Julieta Fernández Ruocco, Fabiano Ferreira, Heitor A Paula-Neto, Marisa Sepúlveda, Martín Vila Petroff, Adriana Bastos Carvalho, Isalira Peroba Ramos, Hugo Justino Branda, Claudia Neto Paiva, Emiliano Medei
Hemodynamic collapse and myocardial dysfunction are among the major causes of death in severe sepsis. The purpose of this study was to assess the role played by TLR4 and by the NLRP3 inflammasome in the cardiac dysfunction that occurs after high-grade polymicrobial sepsis. We performed the colon ascendens stent peritonitis (CASP) surgery in Tlr4, Nlrp3 and caspase-1 mice. We also assessed for the first time the electrical heart function in the CASP model. The QJ interval was increased in wild-type C57BL/6J mice after CASP when compared to sham controls, a result paralleled by an increase in the cardiac action potential duration (APD)...
November 15, 2017: Shock
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