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Cognitive impairment in children

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https://www.readbyqxmd.com/read/28079875/early-postnatal-illness-severity-scores-predict-neurodevelopmental-impairments-at-10-years-of-age-in-children-born-extremely-preterm
#1
J W Logan, O Dammann, E N Allred, C Dammann, K Beam, R M Joseph, T M O'Shea, A Leviton, K C K Kuban
OBJECTIVE: A neonatal illness severity score, The Score for Neonatal Acute Physiology-II (SNAP-II), predicts neurodevelopmental impairments at two years of age among children born extremely preterm. We sought to evaluate to what extent SNAP-II is predictive of cognitive and other neurodevelopmental impairments at 10 years of age. STUDY DESIGN: In a cohort of 874 children born before 28 weeks of gestation, we prospectively collected clinical, physiologic and laboratory data to calculate SNAP-II for each infant...
January 12, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28077012/phonological-working-memory-deficits-in-adhd-revisited
#2
Joseph S Raiker, Lauren M Friedman, Sarah A Orban, Michael J Kofler, Dustin E Sarver, Mark D Rapport
OBJECTIVE: The current study dissociates lower level information-processing abilities (visual registration/encoding, visual-to-phonological conversion, and response output) and examines their contribution to ADHD-related phonological working memory (PHWM) deficits. METHOD: Twenty children with ADHD and 15 typically developing (TD) children completed tasks assessing PHWM, visual registration/encoding, visual-to-phonological conversion, and response output. RESULTS: Relative to TD children, children with ADHD exhibited deficient visual registration/encoding ( d = 0...
January 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28074235/long-term-brain-structural-magnetic-resonance-imaging-and-cognitive-functioning-in-children-treated-for-acute-lymphoblastic-leukemia-with-high-dose-methotrexate-chemotherapy-alone-or-combined-with-cns-radiotherapy-at-reduced-total-dose-to-12%C3%A2-gy
#3
Olga Zając-Spychała, Mikołaj A Pawlak, Katarzyna Karmelita-Katulska, Jakub Pilarczyk, Katarzyna Derwich, Jacek Wachowiak
INTRODUCTION: The aim of this study was to assess the long-term side effects of central nervous system prophylaxis (high-dose chemotherapy alone vs chemotherapy and CNS radiotherapy) according to the ALL IC-BFM 2002. METHODS: Thirty-tree children aged 6.7-19.9 years have been studied. The control group consisted of 12 children newly diagnosed with acute lymphoblastic leukemia. We assessed subcortical gray matter volume using automatic MRI segmentation and cognitive performance to identify differences between two therapeutic schemes and patients prior to treatment...
January 10, 2017: Neuroradiology
https://www.readbyqxmd.com/read/28073356/gut-microbiota-disturbance-during-helminth-infection-can-it-affect-cognition-and-behaviour-of-children
#4
Vanina Guernier, Bradley Brennan, Laith Yakob, Gabriel Milinovich, Archie C A Clements, Ricardo J Soares Magalhaes
BACKGROUND: Bidirectional signalling between the brain and the gastrointestinal tract is regulated at neural, hormonal, and immunological levels. Recent studies have shown that helminth infections can alter the normal gut microbiota. Studies have also shown that the gut microbiota is instrumental in the normal development, maturation and function of the brain. The pathophysiological pathways by which helminth infections contribute to altered cognitive function remain poorly understood...
January 10, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28073351/exploring-neurodevelopmental-outcome-measures-used-in-children-with-cerebral-malaria-the-perspectives-of-caregivers-and-health-workers-in-malawi
#5
Emmie W Mbale, Terrie Taylor, Bernard Brabin, Macpherson Mallewa, Melissa Gladstone
BACKGROUND: Progress has been made in tackling malaria however there are still over 207 million cases worldwide, the majority in children. As survival rates improve, numbers of children with long-term neurodisabling sequelae are likely to increase. Most outcome studies in cerebral malaria (CM) have focused only on body function and structure and less on outcomes within the broader framework of the International Classification of Functioning and Disability (ICF). The aim of this study was to utilise qualitative methods to identify relevant clinical outcomes in CM to support formulation of a core outcome set relevant to CM and other acquired brain injuries for use in future clinical trials...
January 10, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28073076/spastic-diplegia-in-preterm-born-children-executive-function-impairment-and-neuroanatomical-correlates
#6
Maria Chiara Di Lieto, Paola Brovedani, Chiara Pecini, Anna Maria Chilosi, Vittorio Belmonti, Franco Fabbro, Cosimo Urgesi, Simona Fiori, Andrea Guzzetta, Silvia Perazza, Elisa Sicola, Giovanni Cioni
BACKGROUND: The neuropsychological literature on preterm-born children with spastic diplegia due to periventricular leukomalacia is convergent in reporting deficits in non-verbal intelligence and in visuo-spatial abilities. Nevertheless, other cognitive functions have found to be impaired, but data are scant and not correlated with neuroimaging findings. AIMS: This study analyzes the neuropsychological strengths and weaknesses in preterm-born children with spastic diplegia (pSD) and their relationships with neuroanatomical findings, investigated by a novel scale for MRI classification...
January 7, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28066897/predictive-value-of-the-movement-assessment-battery-for-children-second-edition-at-4%C3%A2-years-for-motor-impairment-at-8%C3%A2-years-in-children-born-preterm
#7
Alison Griffiths, Prue Morgan, Peter J Anderson, Lex W Doyle, Katherine J Lee, Alicia J Spittle
AIM: To assess the predictive validity at 4 years of the Movement Assessment Battery for Children - Second Edition (MABC-2) for motor impairment at 8 years in children born preterm. We also aimed to determine if sex, cognition, medical, or social risks were associated with motor impairment at 8 years or with a change in MABC-2 score between 4 years and 8 years. METHOD: Ninety-six children born at less than 30 weeks' gestation were assessed with the MABC-2 at 4 years and 8 years of age...
January 9, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28066108/neuroprotective-effect-of-celastrus-paniculatus-on-chronic-stress-induced-cognitive-impairment
#8
V Bhagya, Thomas Christofer, B S Shankaranarayana Rao
OBJECTIVE: Several studies report that chronic stress results in impaired spatial learning and working memory and enhanced anxiety-like behavior. However, not many studies have looked into the possible ways of reversing stress-induced deficits. Celastrus paniculatus (CP), a traditional ayurvedic herbal medicine, was used to treat cognitive deficits in mentally retarded children. CP oil has been reported to have neuroprotective and antioxidant activities. However, the effects of CP oil on chronic stress-induced cognitive deficits are unclear...
November 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/28065388/a-systematic-review-of-cognitive-function-and-psychosocial-well-being-in-school-age-children-with-narcolepsy
#9
REVIEW
Jane E Blackwell, Hetaf A Alammar, Anna R Weighall, Ian Kellar, Hannah M Nash
In August 2010, concerns were raised about an increase in the incidence rate of narcolepsy diagnosis in children and adolescents. Narcolepsy is a chronic neurological sleep disorder characterised by excessive daytime sleepiness and attacks of muscle weakness which are often precipitated by strong emotions, known as cataplexy. We systematically examined and updated the scientific literature on the consequences of narcolepsy on cognitive function and psychosocial well-being in school-age children. Eight studies published between 2005 and 2015 were eligible for inclusion in this review...
July 18, 2016: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28062262/the-interplay-of-childhood-behavior-problems-and-iq-in-the-development-of-later-schizophrenia-and-affective-psychoses
#10
Jessica Agnew-Blais, Larry J Seidman, Garrett M Fitzmaurice, Jordan W Smoller, Jill M Goldstein, Stephen L Buka
Schizophrenia and affective psychoses are both associated with impaired social functioning, but the extent to which childhood behavioral impairments are present prior to onset of illness is less well studied. Moreover, the concurrent relationship of childhood behavior problems and premorbid IQ with subsequent psychotic disorder has not been established. We investigated whether childhood behavior problems are associated with increased risk for adult schizophrenia or affective psychosis, independently and in combination with IQ...
January 3, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28059932/a-developmental-perspective-on-social-cognition-difficulties-in-youth-at-clinical-high-risk-for-psychosis
#11
Sarah Hope Lincoln, Emily M Norkett, Katherine H Frost, Joseph Gonzalez-Heydrich, Eugene J D'Angelo
After participating in this activity, learners should be better able to:• Evaluate the evolution of social cognitive abilities as a developmental process• Assess the evidence regarding social cognition difficulties in youth at clinical high risk for psychosisIndividuals at clinical high risk (CHR) for psychosis exhibit a broad range of difficulties, including impaired social cognition, which may represent a target for early identification and intervention. Several studies have examined various domains of social cognition in CHR individuals...
January 2017: Harvard Review of Psychiatry
https://www.readbyqxmd.com/read/28050707/effect-of-parental-obesity-and-gestational-diabetes-on-child-neuropsychological-and-behavioral-development-at-4%C3%A2-years-of-age-the-rhea-mother-child-cohort-crete-greece
#12
Vasiliki Daraki, Theano Roumeliotaki, Katerina Koutra, Vaggelis Georgiou, Mariza Kampouri, Andriani Kyriklaki, Marina Vafeiadi, Stathis Papavasiliou, Manolis Kogevinas, Leda Chatzi
Studies have suggested an association between maternal obesity pre-pregnancy and gestational diabetes (GDM) with impaired offspring neurodevelopment, but it is not clear if these associations are explained by shared familiar characteristics. We aimed to assess the associations of maternal and paternal obesity, maternal glucose intolerance in early pregnancy and GDM, with offspring neurodevelopment at 4 years of age. We included 772 mother-child pairs from the "Rhea" Mother-Child cohort in Crete, Greece. Data on maternal/paternal body mass index (BMI) and maternal fasting serum samples for glucose and insulin measurements were collected at 12 weeks of gestation...
January 3, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28045591/clinical-practice-guideline-update
#13
Seth R Schwartz, Anthony E Magit, Richard M Rosenfeld, Bopanna B Ballachanda, Jesse M Hackell, Helene J Krouse, Claire M Lawlor, Kenneth Lin, Kourosh Parham, David R Stutz, Sandy Walsh, Erika A Woodson, Ken Yanagisawa, Eugene R Cunningham
Objective This update of the 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation cerumen impaction clinical practice guideline provides evidence-based recommendations on managing cerumen impaction. Cerumen impaction is defined as an accumulation of cerumen that causes symptoms, prevents assessment of the ear, or both. Changes from the prior guideline include a consumer added to the development group; new evidence (3 guidelines, 5 systematic reviews, and 6 randomized controlled trials); enhanced information on patient education and counseling; a new algorithm to clarify action statement relationships; expanded action statement profiles to explicitly state quality improvement opportunities, confidence in the evidence, intentional vagueness, and differences of opinion; an enhanced external review process to include public comment and journal peer review; and 3 new key action statements on managing cerumen impaction that focus on primary prevention, contraindicated intervention, and referral and coordination of care...
January 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28045463/neurogenetics-of-developmental-dyslexia-from-genes-to-behavior-through-brain-neuroimaging-and-cognitive-and-sensorial-mechanisms
#14
REVIEW
S Mascheretti, A De Luca, V Trezzi, D Peruzzo, A Nordio, C Marino, F Arrigoni
Developmental dyslexia (DD) is a complex neurodevelopmental deficit characterized by impaired reading acquisition, in spite of adequate neurological and sensorial conditions, educational opportunities and normal intelligence. Despite the successful characterization of DD-susceptibility genes, we are far from understanding the molecular etiological pathways underlying the development of reading (dis)ability. By focusing mainly on clinical phenotypes, the molecular genetics approach has yielded mixed results...
January 3, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28044261/cognitive-development-in-a-young-child-with-mucolipidosis-type-iv-a-case-report
#15
Evelyn L Fisher, Rose A Sevcik, MaryAnn Romski
Mucolipidosis Type IV (ML IV) is an autosomal recessive genetic disorder characterized by severe psychomotor impairments and ophthalmologic abnormalities. Reports on the cognitive development of people with ML IV are limited, but suggest that achievement of language and cognitive milestones varies between a 3- and 18-month level. There is also variability in reports of whether people with ML IV make developmental progress, regress, or remain static after infancy. This study examines the longitudinal development of a young child with ML IV who participated in an augmentative and alternative communication (AAC) intervention...
January 3, 2017: JIMD Reports
https://www.readbyqxmd.com/read/28032202/pediatric-obsessive-compulsive-disorder-with-tic-symptoms-clinical-presentation-and-treatment-outcome
#16
Davíð R M A Højgaard, Gudmundur Skarphedinsson, Judith Becker Nissen, Katja A Hybel, Tord Ivarsson, Per Hove Thomsen
: Some studies have shown that children and adolescents with obsessive-compulsive disorder (OCD) and co-morbid tics differ from those without co-morbid tics in terms of several demographic and clinical characteristics. However, not all studies have confirmed these differences. This study examined children and adolescents with OCD and with possible or definite tic specifiers according to the DSM-5 in order to see whether they differ from patients without any tic symptoms regarding clinical presentation and outcome of cognitive behavioral therapy (CBT)...
December 28, 2016: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28028677/psychosocial-influences-on-disaster-preparedness-in-san-francisco-recipients-of-home-care
#17
Robyn R Gershon, Elena Portacolone, Ezinne M Nwankwo, Qi Zhi, Kristine A Qureshi, Victoria H Raveis
Disasters disproportionately impact certain segments of the population, including children, pregnant women, people living with disabilities and chronic conditions and those who are underserved and under-resourced. One of the most vulnerable groups includes the community-dwelling elderly. Post-disaster analyses indicate that these individuals have higher risk of disaster-related morbidity and mortality. They also have suboptimal levels of disaster preparedness in terms of their ability to shelter-in-place or evacuate to a shelter...
December 27, 2016: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28018896/factors-influencing-neurodevelopment-after-cardiac-surgery-during-infancy
#18
REVIEW
Hedwig Hubertine Hövels-Gürich
Short- and long-term neurodevelopmental (ND) disabilities with negative impact on psychosocial and academic performance, quality of life, and independence in adulthood are known to be the most common sequelae for surviving children after surgery for congenital heart disease (CHD). This article reviews influences and risk factors for ND impairment. For a long time, the search for independent risk factors was focused on the perioperative period and modalities of cardiopulmonary bypass (CPB). CPB operations to ensure intraoperative vital organ perfusion and oxygen supply with or without circulatory arrest or regional cerebral perfusion bear specific risks...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28012522/comparison-of-intelligence-quotients-of-first-and-second-generation-deaf-children-with-cochlear-implants
#19
K Amraei, S Amirsalari, M Ajalloueyan
Hearing impairment is a common type of sensory loss in children. Studies indicate that children with hearing impairment are deficient in social, cognitive and communication skills. This study compared the intelligence quotients of first- and second-generation deaf children with cochlear implants. This research is causal-comparative. All 15 deaf children investigated had deaf parents and were selected from Baqiyatallah Cochlear Implant Center. The 15 children with cochlear implants were paired with similar children with hearing parents using purposive sampling...
January 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28011793/protecting-the-premature-brain-current-evidence-based-strategies-for-minimising-perinatal-brain-injury-in-preterm-infants
#20
Charlotte L Lea, Adam Smith-Collins, Karen Luyt
Improving neurodevelopmental outcome for preterm infants is an important challenge for neonatal medicine. The disruption of normal brain growth and neurological development is a significant consequence of preterm birth and can result in physical and cognitive impairments. While advances in neonatal medicine have led to progressively better survival rates for preterm infants, there has only been a modest improvement in the proportion of surviving infants without neurological impairment, and no change in the proportion with severe disability...
December 23, 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
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