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https://www.readbyqxmd.com/read/28881155/seasonal-patterns-of-asthma-medication-fills-among-diverse-populations-of-the-united-states
#1
Kedir N Turi, Tebeb Gebretsadik, Rees L Lee, Tina V Hartert, Amber M Evans, Cosby Stone, Nicholas M Sicignano, Ann C Wu, Carlos Iribarren, Melissa G Butler, Edward Mitchel, James Morrow, Emma K Larkin, Pingsheng Wu
OBJECTIVE: Nonadherence to controller and overuse of reliever asthma medications are associated with exacerbations. We aimed to determine patterns of seasonal asthma medication use and to identify time period(s) during which interventions to improve medication adherence could reduce asthma morbidity. METHODS: We conducted a retrospective cohort study of asthmatics 4-50 years of age and enrolled in three diverse health insurance plans. Seasonal patterns of medications were reported by monthly prescription fill rates per 1000 individuals with asthma from 1998 to 2013, and stratified by healthcare plan, sex, and age...
September 7, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28793130/time-trends-in-physical-activity-of-adult-users-of-the-brazilian-national-health-system-2010-2014-longitudinal-study
#2
Bruna Camilo Turi, Jamile Sanches Codogno, Rômulo Araújo Fernandes, Kyle Robinson Lynch, Eduardo Kokubun, Henrique Luiz Monteiro
CONTEXT AND OBJECTIVE: In this longitudinal study, we aimed to describe time trends of physical activity (PA) in different domains from 2010 to 2014 among users of the Brazilian National Health System, taking into account the effects of sex, age and economic status (ES). DESIGN AND SETTING: Longitudinal study conducted in five primary care units in Bauru (SP), Brazil. METHODS: The sample was composed of 620 men and women who were interviewed in 2010, 2012 and 2014...
July 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28777459/iodixanol-versus-iopromide-in-cancer-patients-evidence-from-a-randomized-clinical-trial
#3
Irene Terrenato, Francesca Sperati, Felice Musicco, Anna F Pozzi, Annunziata di Turi, Mauro Caterino, Elisabetta de Lutio di Castelguidone, Sergio V Setola, Massimo Bellomi, Carlo E Neumaier, Laura Conti, Giovanni Cigliana, Roberta Merola, Anna Antenucci, Giulia Orlandi, Antonio Giordano, Maddalena Barba, Stefano Canitano
To assess the safety profile of iso-osmolar contrast medium (CM) versus low osmolar CM in cancer patients with an estimated glomerular filtration rate (eGFR) >60 ml/min. In this multicenter, blind trial of patients seeking a chest-abdomen-pelvis contrast enhanced computed tomography (CT) with iodated CM, participants were centrally randomized to iodixanol or iopromide. Contrast induced nephropathy (CIN) at 24 and/or 72 hr were our primary outcomes. We further considered irreversible CIN, average eGFR percentage variation (%Δ), and adverse events (AEs)...
August 4, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28765126/cost-utility-and-budget-impact-analyses-of-the-use-of-nepa-for-chemotherapy-induced-nausea-and-vomiting-prophylaxis-in-italy
#4
Umberto Restelli, Gabriella Saibene, Patrizia Nardulli, Roberta Di Turi, Erminio Bonizzoni, Francesca Scolari, Tania Perrone, Davide Croce, Luigi Celio
OBJECTIVE: To evaluate the efficiency of resources allocation and sustainability of the use of netupitant+palonosetron (NEPA) for chemotherapy-induced nausea and vomiting (CINV) prophylaxis assuming the Italian National Health Service (NHS) perspective. A published Markov model was adapted to assess the incremental cost-utility ratio of NEPA compared with aprepitant (APR) + palonosetron (PALO), fosaprepitant (fAPR) + PALO, APR + ondansetron (ONDA), fAPR + ONDA in patients receiving a highly emetogenic chemotherapy (HEC) and with APR + PALO and fAPR + PALO in patients receiving a moderately emetogenic chemotherapy (MEC)...
August 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/28756254/evaluation-of-chlorpyrifos-effects-alone-and-combined-with-lipopolysaccharide-stress-on-dna-integrity-and-immune-responses-of-the-three-spined-stickleback-gasterosteus-aculeatus
#5
Adrien Marchand, Jean-Marc Porcher, Cyril Turies, Edith Chadili, Olivier Palluel, Patrick Baudoin, Stéphane Betoulle, Anne Bado-Nilles
Organism immune defences might be weakened by pollutants, largely detected in aquatic ecosystems, leading to the facilitation for opportunistic pathogens to infect organisms. In this context, destabilization of fish non-specific immune parameters and erythrocyte DNA integrity was tested, on a model fish species, the three-spined stickleback (Gasterosteus aculeatus), after exposure to chlorpyrifos (CPF). Alone, pesticide exposure induced a genotoxic potential (chlorpyrifos at 1.75 and 0.88µg/L) in addition to a decrease in phagocytosis capacity and a stimulation of respiratory burst...
July 27, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28639293/-although-we-re-isolated-we-re-not-really-isolated-the-value-of-information-and-communication-technology-for-older-people-in-rural-australia
#6
Turi Berg, Rachel Winterton, Maree Petersen, Jeni Warburton
OBJECTIVE: Drawing from a larger study that identified the supports and services that facilitate wellness among older people from rural communities, this study examined the specific contribution made by information and communication technology (ICT). METHODS: Qualitative interviews were undertaken with 60 older adults from six Australian rural areas. A preliminary thematic analysis was conducted, followed by a higher-order inductive analysis. RESULTS: Information and communication technology use was discussed in terms of individual enrichment, and in terms of enabling connections between the individual and their social networks, community and wider service environments...
June 22, 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28612412/ending-poke-until-you-get-a-gusher-part-ii-the-evidence-based-approach-to-vascular-access-revisited
#7
EDITORIAL
Zoltan G Turi
Puncture above the common femoral bifurcation and below the inguinal ligament is optimal A vast majority of femoral bifurcations occur below the middle third of the femoral head while the inferior epigastric artery rarely descends below the middle third Fluoroscopy or if possible, ultrasound, should be used for femoral access to optimize safe puncture.
June 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28605234/the-impact-of-training-load-on-bone-mineral-density-of-adolescent-swimmers-a-structural-equation-modeling-approach
#8
Ricardo Ribeiro Agostinete, Santiago Maillane-Vanegas, Kyle R Lynch, Bruna Turi-Lynch, Manuel João Coelho-E-Silva, Eduardo Zapaterra Campos, Suziane Ungari Cayres, Romulo Araújo Fernandes
PURPOSE: To investigate the mediating effect of muscle mass on the relationship between training load and bone density in adolescent swimmers. METHODS: A cross-sectional study involving 87 control and 22 swimmers aged 10-19 years (overall sample, n= 109). Swimmers had a minimum of one year of competition in regional and national championships, and control adolescents reported one year without any organized sport. Bone density was the main outcome (dual energy X-ray absorptiometry), which was measured in upper-limbs, lower-limbs, spine, and whole-body...
June 12, 2017: Pediatric Exercise Science
https://www.readbyqxmd.com/read/28568707/hemispheric-language-organization-after-congenital-left-brain-lesions-a-comparison-between-functional-transcranial-doppler-and-functional-mri
#9
Anna Maria Chilosi, Sara Bulgheroni, Marco Turi, Paola Cristofani, Laura Biagi, Alessandra Erbetta, Daria Riva, Anna Nigri, Luigi Caputi, Nicola Giannini, Simona Fiori, Chiara Pecini, Francesca Perego, Michela Tosetti, Paola Cipriani, Giovanni Cioni
This study investigated whether functional transcranial Doppler ultrasound (fTCD) is a suitable tool for studying hemispheric lateralization of language in patients with pre-perinatal left hemisphere (LH) lesions and right hemiparesis. Eighteen left-hemisphere-damaged children and young adults and 18 healthy controls were assessed by fTCD and fMRI to evaluate hemispheric activation during two language tasks: a fTCD animation description task and a fMRI covert rhyme generation task. Lateralization indices (LIs), measured by the two methods, differed significantly between the two groups, for a clear LH dominance in healthy participants and a prevalent activation of right hemisphere in more than 80% of brain-damaged patients...
May 31, 2017: Journal of Neuropsychology
https://www.readbyqxmd.com/read/28488412/revisiting-femoral-vs-radial-access-do-vascular-closure-devices-level-the-playing-field
#10
EDITORIAL
Tilak K R Pasala, Zoltan G Turi
Previous large randomized multicenter trials have shown superiority of radial to femoral access in reducing major bleeding, vascular complications, and in some cohorts, mortality Vascular closure devices improve time to hemostasis and ambulation, as well as patient comfort, but have not been shown to reduce major complications or mortality consistently in the high level evidence base. The combination of optimal femoral access and closure with a vascular closure device has the potential to narrow the gap between the radial and femoral approaches in high risk patients, but unfortunately this study was too limited to confirm either non-inferiority or equivalence...
May 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28479327/a-review-of-metabolomics-approaches-and-their-application-in-identifying-causal-pathways-of-childhood-asthma
#11
Kedir N Turi, Lindsey Romick-Rosendale, Kelli K Ryckman, Tina V Hartert
Because asthma is a disease that results from host-environment interactions, an approach that allows assessment of the effect of the environment on the host is needed to understand the disease. Metabolomics has appealing potential as an application to study pathways to childhood asthma development. The objective of this review is to provide an overview of metabolomics methods and their application to understanding host-environment pathways in asthma development. We reviewed recent literature on advances in metabolomics and their application to study pathways to childhood asthma development...
May 4, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28475840/electronic-excited-state-lifetimes-of-anionic-water-clusters-dependence-on-charge-solvation-motif
#12
Daniel Borgis, Peter J Rossky, László Turi
An ongoing controversy about water cluster anions concerns the electron-binding motif, whether the charge center is localized at the surface or within the cluster interior. Here, mixed quantum-classical dynamics simulations have been carried out for a wide range of cluster sizes (n ≤ 1000) for (H2O)n(-) and (D2O)n(-), based on a nonequilibrium first-order rate constant approach. The computed data are in good general agreement with time-resolved photoelectron imaging results (n ≤ 200). The analysis reveals that, for surface state electrons, the cluster size dependence of the excited state electronic energy gap and the magnitude of the nonadiabatic couplings have compensating influences on the excited state lifetimes: the excited state lifetime for surface states reaches a minimum for n ∼ 150 and then increases for larger clusters...
May 10, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28471926/a-literature-review-of-psychosocial-comorbidities-related-to-working-capacity-after-aneurysmal-subarachnoid-hemorrhage
#13
REVIEW
Eleanor Turi, Yvette Conley, Ansley Grimes Stanfill
OBJECTIVE: The aim of this study was to describe literature regarding the impact of psychosocial comorbidities on working capacity after aneurysmal subarachnoid hemorrhage (aSAH). DESIGN/METHODS: This study is a review of the literature using PubMed, CINAHL, PyschINFO, and Google Scholar. RESULTS: Patients with aSAH affected by depression, anxiety, cognitive impairment, or posttraumatic stress disorder are less likely to return to work, although there are mixed results...
June 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28430909/clinical-trial-principles-and-endpoint-definitions-for-paravalvular-leaks-in-surgical-prosthesis-an-expert-statement
#14
Carlos E Ruiz, Rebecca T Hahn, Alain Berrebi, Jeffrey S Borer, Donald E Cutlip, Greg Fontana, Gino Gerosa, Reda Ibrahim, Vladimir Jelnin, Hasan Jilaihawi, E Marc Jolicoeur, Chad Kliger, Itzhak Kronzon, Jonathon Leipsic, Francesco Maisano, Xavier Millan, Patrick Nataf, Patrick T O'Gara, Philippe Pibarot, Stephen R Ramee, Charanjit S Rihal, Josep Rodes-Cabau, Paul Sorajja, Rakesh Suri, Julie A Swain, Zoltan G Turi, E Murat Tuzcu, Neil J Weissman, Jose L Zamorano, Patrick W Serruys, Martin B Leon
The VARC (Valve Academic Research Consortium) for transcatheter aortic valve replacement set the standard for selecting appropriate clinical endpoints reflecting safety and effectiveness of transcatheter devices, and defining single and composite clinical endpoints for clinical trials. No such standardization exists for circumferentially sutured surgical valve paravalvular leak (PVL) closure. This document seeks to provide core principles, appropriate clinical endpoints, and endpoint definitions to be used in clinical trials of PVL closure devices...
April 18, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28427582/clinical-trial-principles-and-endpoint-definitions-for-paravalvular-leaks-in-surgical-prosthesis-an-expert-statement
#15
REVIEW
Carlos E Ruiz, Rebecca T Hahn, Alain Berrebi, Jeffrey S Borer, Donald E Cutlip, Greg Fontana, Gino Gerosa, Reda Ibrahim, Vladimir Jelnin, Hasan Jilaihawi, E Marc Jolicoeur, Chad Kliger, Itzhak Kronzon, Jonathon Leipsic, Francesco Maisano, Xavier Millan, Patrick Nataf, Patrick T O'Gara, Philippe Pibarot, Stephen R Ramee, Charanjit S Rihal, Josep Rodes-Cabau, Paul Sorajja, Rakesh Suri, Julie A Swain, Zoltan G Turi, E Murat Tuzcu, Neil J Weissman, Jose L Zamorano, Patrick W Serruys, Martin B Leon
The VARC (Valve Academic Research Consortium) for transcatheter aortic valve replacement set the standard for selecting appropriate clinical endpoints reflecting safety and effectiveness of transcatheter devices, and defining single and composite clinical endpoints for clinical trials. No such standardization exists for circumferentially sutured surgical valve paravalvular leak (PVL) closure. This document seeks to provide core principles, appropriate clinical endpoints, and endpoint definitions to be used in clinical trials of PVL closure devices...
April 25, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28424379/-risk-factors-of-eating-disorders-in-the-narratives-of-fashion-models
#16
Nikolett Bogár, Ferenc Túry
INTRODUCTION: The risk of eating disorders is high in populations who are exposed to slimness ideal, so among fashion models. The present qualitative study evaluates the risk factors of eating disorders in a group of fashion models with semistructured interview. Moreover, the aim of the study was to examine the impact of professional requirements on the health of models. METHODS: The study group was internationally heterogeneous. The models were involved by personal professional relationship...
2017: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/28392704/predictive-parameters-in-hypofractionated-whole-breast-3d-conformal-radiotherapy-according-to-the-ontario-canadian-trial
#17
Grazia Lazzari, Angela Terlizzi, Giuseppina Della Vittoria Scarpati, Francesco Perri, Vincenzo De Chiara, Barbara Turi, Giovanni Silvano
AIM: To evaluate the possible role of dosimetric parameters according Normal Tissue Complication Probability (NTCP) model as predictive of late toxicity and cosmesis in hypofractionated whole-breast three-dimensional conformal radiotherapy. PATIENTS AND METHODS: A retrospective analysis on 215 consecutive early breast cancer patients treated with breast conserving surgery and adjuvant hypofractionated whole-breast radiotherapy (according the Ontario Canadian trial), with a 6 years median follow-up was conducted...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28380203/determinants-of-outpatient-expenditure-within-primary-care-in-the-brazilian-national-health-system
#18
Bruna Camilo Turi, Jamile Sanches Codogno, Flávia Mori Sarti, Nana Kwame Anokye, Rômulo Araújo Fernandes, Henrique Luiz Monteiro
CONTEXT AND OBJECTIVE: One of the big challenges facing governments worldwide is the financing of healthcare systems. Thus, it is necessary to understand the factors and key components associated with healthcare expenditure. The aim here was to identify demographic, socioeconomic, lifestyle and clinical factors associated with direct healthcare expenditure within primary care, among adults attended through the Brazilian National Health System in the city of Bauru. DESIGN AND SETTING: Cross-sectional study conducted in five primary care units in Bauru (SP), Brazil...
May 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28352948/visual-information-from-observing-grasping-movement-in-allocentric-and-egocentric-perspectives-development-in-typical-children
#19
Francesca Tinelli, Giovanni Cioni, Giulio Sandini, Marco Turi, Maria Concetta Morrone
Development of the motor system lags behind that of the visual system and might delay some visual properties more closely linked to action. We measured the developmental trajectory of the discrimination of object size from observation of the biological motion of a grasping action in egocentric and allocentric viewpoints (observing action of others or self), in children and adolescents from 5 to 18 years of age. Children of 5-7 years of age performed the task at chance, indicating a delayed ability to understand the goal of the action...
March 28, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28330913/reconciling-evidence-from-ancient-and-contemporary-genomes-a-major-source-for-the-european-neolithic-within-mediterranean-europe
#20
Joana B Pereira, Marta D Costa, Daniel Vieira, Maria Pala, Lisa Bamford, Nourdin Harich, Lotfi Cherni, Farida Alshamali, Jiři Hatina, Sergey Rychkov, Gheorghe Stefanescu, Turi King, Antonio Torroni, Pedro Soares, Luísa Pereira, Martin B Richards
Important gaps remain in our understanding of the spread of farming into Europe, due partly to apparent contradictions between studies of contemporary genetic variation and ancient DNA. It seems clear that farming was introduced into central, northern, and eastern Europe from the south by pioneer colonization. It is often argued that these dispersals originated in the Near East, where the potential source genetic pool resembles that of the early European farmers, but clear ancient DNA evidence from Mediterranean Europe is lacking, and there are suggestions that Mediterranean Europe may have resembled the Near East more than the rest of Europe in the Mesolithic...
March 29, 2017: Proceedings. Biological Sciences
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