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https://www.readbyqxmd.com/read/28797611/video-instruction-is-more-effective-than-written-instruction-in-improving-inhaler-technique
#1
Romil F Shah, Rakesh M Gupta
INTRODUCTION: Many patients with asthma use inhalers incorrectly. Better inhaler technique is associated with better asthma control. We tested the effectiveness of a computer-based video training solution versus traditional written instructions, both which may be used in a resource-limited setting, for teaching inhaler technique. We hypothesized that computer based training will provide a higher quality of instruction which will improve technique more effectively than written training...
August 7, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28729297/association-between-intracranial-atherosclerotic-calcium-burden-and-angiographic-luminal-stenosis-measurements
#2
H Baradaran, P Patel, G Gialdini, A Giambrone, M P Lerario, B B Navi, J K Min, C Iadecola, H Kamel, A Gupta
BACKGROUND AND PURPOSE: Calcification of the intracranial vasculature is an independent risk factor for stroke. The relationship between luminal stenosis and calcium burden in the intracranial circulation is incompletely understood. We evaluated the relationship between atherosclerotic calcification and luminal stenosis in the intracranial ICAs. MATERIALS AND METHODS: Using a prospective stroke registry, we identified patients who had both NCCT and CTA or MRA examinations as part of a diagnostic evaluation for ischemic stroke...
July 20, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28688017/what-factors-predict-conversion-to-tha-after-arthroscopy
#3
John M Redmond, Asheesh Gupta, Kevin Dunne, Ammar Humayun, Leslie C Yuen, Benjamin G Domb
BACKGROUND: Failure of hip preservation to alleviate symptoms potentially subjects the patient to reoperation or conversion surgery to THA, adding recovery time, risk, and cost. A risk calculator using an algorithm that can predict the likelihood that a patient who undergoes arthroscopic hip surgery will undergo THA within 2 years would be helpful, but to our knowledge, no such tool exists. QUESTIONS: (1) Are there preoperative and intraoperative variables at the time of hip arthroscopy associated with subsequent conversion to THA? (2) Can these variables be used to develop a predictive tool for conversion to THA? MATERIALS AND METHODS: All patients undergoing arthroscopy from January 2009 through December 2011 were registered in our longitudinal database...
July 7, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28584536/comparative-assessment-of-salivary-cotinine-level-and-psychological-dependence-among-tobacco-users
#4
Vrushali D Patel, Kiran B Jadhav, Vandana S Shah, Nidhi D Gupta
BACKGROUND: The aim of the study was to assess the correlation between salivary cotinine level and psychological dependence measured through Fagerstrom test for nicotine dependence (FTND) questionnaire among tobacco users. MATERIALS AND METHODS: This was a cross-sectional study, conducted on tobacco users. Participants with the present habit of tobacco chewing and smoking above the age of 16 years were included in the study. A standard questionnaire form of FTND revised version for smoking and smokeless form of tobacco were given to each participant...
March 2017: Dental Research Journal
https://www.readbyqxmd.com/read/28584513/assessment-of-panc3-score-in-predicting-severity-of-acute-pancreatitis
#5
Avreen Singh Shah, Arun Kumar Gupta, Kulwant Singh Ded
INTRODUCTION: Acute pancreatitis is inflammatory process of the pancreas associated with local and systemic complications. At present, there are lots of scores (such as Ransons, APACHE II, bedside index for severity in acute pancreatitis) that help us in predicting severity at the time of admission but these are time consuming or require complex calculation and are costly. MATERIAL AND METHODS: PANC3 Scoring System is one of the better systems because the three criteria used (hematocrit, body mass index, and pleural effusion) are simple, easy to assess, readily available, and economic...
January 2017: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/28577684/electronically-self-assessed-functional-capacity-and-exercise-testing-a-comparison-of-the-duke-activity-status-index-and-patient-reported-outcomes-measurement-information-system-tools
#6
COMPARATIVE STUDY
Ryan A Coute, Jesse M Ehrenfeld, Deepak K Gupta, Maxim A Terekhov, Jonathan P Wanderer
PURPOSE: Electronic screening tools, such as Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function Short-Form 12a (PF-SF12a), may aid in the assessment of functional capacity. However, PROMIS PF-SF12a has not been validated against exercise capacity, or compared with established questionnaires, including the Duke Activity Status Index (DASI). We compared the DASI and PROMIS PF-SF12a to the maximum metabolic equivalents (METs) achieved during exercise stress testing...
June 2017: American Heart Journal
https://www.readbyqxmd.com/read/28373450/human-papilloma-virus-positive-oropharyngeal-squamous-cell-carcinoma-in-the-elderly
#7
Eesha Dave, William Su, Vishal Gupta, Brett Miles, Elizabeth Demicco, Theresa Soriano, Richard L Bakst
BACKGROUND/AIM: Elderly patients with HPV+ oropharyngeal cancer (OPC) represent an understudied cohort of the HPV epidemic. We aimed to investigate the clinical presentation, treatment tolerability and outcomes in patient's ≥65 years old with HPV+ OPC. PATIENTS AND METHODS: We identified all patients aged 65 and older treated at our Institution with HPV+ OPC and analyzed patient demographics, disease characteristics, treatment modalities, toxicities, treatment failures, and survival...
April 2017: Anticancer Research
https://www.readbyqxmd.com/read/28346595/association-of-gastric-acid-suppression-with-recurrent-clostridium-difficile-infection-a-systematic-review-and-meta-analysis
#8
REVIEW
Raseen Tariq, Siddharth Singh, Arjun Gupta, Darrell S Pardi, Sahil Khanna
Importance: Gastric acid suppression has been associated with an increased risk of primary Clostridium difficile infection (CDI), but the risk of recurrent CDI in patients taking gastric acid suppressant medications is unclear. Objective: To perform a systematic review and meta-analysis to evaluate the association between gastric acid suppressants and recurrent CDI. Data Sources: MEDLINE, EMBASE, the Cochrane Central Register, the Cochrane Database, and Web of Science were searched from January 1, 1995, to September 30, 2015, for studies assessing the association between gastric acid suppressant exposure and recurrent CDI...
June 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28190702/analysis-of-low-appropriateness-score-exam-trends-in-decision-support-based-radiology-order-entry-system
#9
Supriya Gupta, Kandace Klein, Anand H Singh, James H Thrall
PURPOSE: Awareness of imaging utilization increased after implementation of Radiology Order Entry with decision support systems (ROE-DS). Our hypothesis is few exams with low Clinical Appropriateness Score (CAS) on ROE-DS are performed. Clinical indications of exams with CAS less than 3 (9-point scale) were re-reviewed and reports analyzed. MATERIALS AND METHODS: Structured Query Language-based query retrieved exams with CAS less than 3 in ROE-DS from January 2007 to December 2011...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28048293/su-f-t-605-implementation-of-the-conformity-gradient-index-cgi-to-intracranial-linac-based-stereotactic-plans-to-evaluate-possible-improvements-in-treatment-planning
#10
A Sandu, S Thompson, A Ayan, J Woollard, N Gupta
PURPOSE: To retrospectively evaluate the planning quality of a sample of intracranial, linac-based, dynamic arc MLC and VMAT stereotactic plans by calculating the effective gradient, Conformity Score (CGIc) and Gradient Score Index (CGIg), and determine if the Conformity/Gradient Index (CGI) may be a useful metric to guide our current treatment planning process. METHODS: We evaluated single lesion VMAT, single lesion dynamic arc, and single isocenter, 2-lesion linac-based, intracranial, VMAT treatment plans originally created in Eclipse™...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28031730/improving-quality-of-home-based-postnatal-care-by-microteaching-of-multipurpose-workers-in-rural-and-urban-slum-areas-of-chandigarh-india-a-pilot-study
#11
Madhu Gupta, Jaya Prasad Tripathy, Limalemla Jamir, Ashutosh Sarwa, Smita Sinha, Chering Bhag
BACKGROUND: Microteaching is an efficient teaching tool to improve skills. Until now, its use is very limited in the health sector. A pilot study was carried out to improve the quality of home-based postnatal care by microteaching of health workers (HWs) and ascertain its feasibility for supportive supervision. METHODS: All (n=12) the HWs catering to a population of ~0.1 million were video recorded while performing home-based postnatal check up in Chandigarh from August 2013 to December 2014...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28029706/morphological-brain-measures-of-cortico-limbic-inhibition-related-to-resilience
#12
Arpana Gupta, Aubrey Love, Lisa A Kilpatrick, Jennifer S Labus, Ravi Bhatt, Lin Chang, Kirsten Tillisch, Bruce Naliboff, Emeran A Mayer
Resilience is the ability to adequately adapt and respond to homeostatic perturbations. Although resilience has been associated with positive health outcomes, the neuro-biological basis of resilience is poorly understood. The aim of the study was to identify associations between regional brain morphology and trait resilience with a focus on resilience-related morphological differences in brain regions involved in cortico-limbic inhibition. The relationship between resilience and measures of affect were also investigated...
September 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27883362/a-risk-factor-based-model-for-upper-aerodigestive-tract-cancers-in-india-predicting-and-validating-the-receiver-operating-characteristic-curve
#13
Bhawna Gupta, Narinder Kumar, Newell W Johnson
BACKGROUND: A study was conducted to develop and validate a screening model using risk scores to identify individuals at high risk for developing upper aerodigestive tract (UADT) cancers in an Indian population. METHODS: A hospital-based case-control study (n = 480) was conducted in Pune, India. We assessed risk factors for UADT cancers by administering a questionnaire through face-to-face interviews. We developed a risk factor model based on the statistically significant risk factors in multiple logistic regression...
July 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/27759595/survival-differences-among-uterine-papillary-serous-clear-cell-and-grade-3-endometrioid-adenocarcinoma-endometrial-cancers-a-national-cancer-database-analysis
#14
Mary McGunigal, Jerry Liu, Tamara Kalir, Manjeet Chadha, Vishal Gupta
OBJECTIVES: High-risk histology including UPSC, CC, and high-grade (G3) endometrioid adenocarcinoma (EAC) have a worse prognosis compared to G1-2 EAC. It is unknown whether G3EAC outcomes are more similar to UPSC/CC or to G1-2 EAC. The purpose of this study was to compare overall survival (OS) among UPSC, CC, and G1-3 EAC, for International Federation of Gynecology and Obstetrics stages I to III. METHODS: The National Cancer Data Base was queried for patients diagnosed with International Federation of Gynecology and Obstetrics (1988 classification) Stage I-III UPSC, CC, and EAC from 1998 to 2012 who underwent surgery as definitive treatment...
January 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27753658/immunohistochemical-expression-of-antitissue-transglutaminase-2-in-tissue-injuries-an-interpretation-beyond-celiac-disease
#15
Prasenjit Das, Ramakant Rawat, Anil K Verma, Geetika Singh, Archana G Vallonthaiel, Rajni Yadav, Gaurav P S Gahlot, Amit K Dinda, Vineet Ahuja, Siddhartha Datta Gupta, Sanjay K Agarwal, Govind K Makharia
Tissue transglutaminase 2 enzyme plays a diverse role in intracellular and extracellular functioning. Aberrant expression of anti-TG2 antibody has recently been proposed for extraintestinal identification of celiac disease (CeD), but its utility is questionable. To examine whether anti-TG2 immunohistochemical (IHC) staining can be of diagnostic value in identifying extraintestinal involvement in CeD, tissue blocks of patients with IgA nephropathies (IgAN), minimal change disease, membranous glomerulonephritis, membrano-proliferative glomerulonephritis, normal kidney, intestinal biopsies from CeD, tropical sprue, nonspecific duodenitis, and inflammatory bowel disease; liver biopsies from patients with chronic hepatitis B and C, acute liver failure (ALF), and CeD-associated liver diseases were retrieved and subjected to IHC staining for anti-tissue transglutaminase 2 enzyme...
October 7, 2016: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/27721277/does-hepatocyte-paraffin-1-expression-stand-a-role-in-determining-the-site-origin-of-an-adenocarcinoma-from-unknown-gastrointestinal-primary
#16
Rajni Yadav, Saurav Chopra, Aayushi Garg, Brijnandan Gupta, Prateek Kinra, Siddhartha Datta Gupta, Prasenjit Das
BACKGROUND: Hepatocyte Paraffin 1 (Hep Par 1) was being extensively used to recognize the hepatocellular carcinomas, until recognition of its expression in tumors without hepatocellular differentiation. AIMS AND OBJECTIVES: The aim of this study was to analyze if Hep Par 1 stain can serve as a specific marker of the small intestinal (SI) adenocarcinomas, versus other gastrointestinal tract (GIT) primary tumors. MATERIALS AND METHODS: In this retrospective cross-sectional study, normal GIT mucosa (n - 60), corresponding adenocarcinomas (n - 60) and nodal metastatic foci (n - 60) from the same patients, including 10 cases each from the esophagus, stomach, SI periampullary region, colon, rectum, and gall bladder were included...
October 2016: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/27667119/validation-of-international-trauma-scoring-systems-in-urban-trauma-centres-in-india
#17
Nobhojit Roy, Martin Gerdin, Eric Schneider, Deepa K Kizhakke Veetil, Monty Khajanchi, Vineet Kumar, Makhal Lal Saha, Satish Dharap, Amit Gupta, Göran Tomson, Johan von Schreeb
INTRODUCTION: In the Lower-Middle Income Country setting, we validate trauma severity scoring systems, namely Injury Severity Score (ISS), New Injury Severity Scale (NISS) score, the Kampala Trauma Score (KTS), Revised Trauma Score (RTS) score and the TRauma Injury Severity Score (TRISS) using Indian trauma patients. PATIENTS AND METHODS: From 1 September 2013 to 28 February 2015, we conducted a prospective multi-centre observational cohort study of trauma patients in four Indian university hospitals, in three megacities, Kolkata, Mumbai and Delhi...
November 2016: Injury
https://www.readbyqxmd.com/read/27663655/sonoelastography-of-musculoskeletal-soft-tissue-masses-a-pilot-study-of-quantitative-evaluation
#18
Bill Pass, Maria Johnson, Elizabeth M A Hensor, Harun Gupta, Philip Robinson
OBJECTIVES: To evaluate quantitative sonoelastography of benign and malignant musculoskeletal soft tissue masses. METHODS: We conducted a prospective study of 50 patients from a specialist sarcoma center who had extremity soft tissue masses referred for biopsy. After consent, the quantitative shear wave velocity (meters per second) was measured in longitudinal and transverse planes (3 readings in each plane and mean calculated). All masses subsequently underwent biopsy, excision, or both, with the histologic diagnosis taken as the reference standard...
October 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27608686/clinical-profile-of-patients-requiring-prolonged-mechanical-ventilation-and-their-outcome-in-a-tertiary-care-medical-icu
#19
Chakor S Vora, Niteen D Karnik, Vishal Gupta, Milind Y Nadkar, Jaimala V Shetye
INTODUCTION: An increasing number of patients require mechanical ventilation and there has been a proportional increase in patients needing prolonged mechanical ventilation (ventilated for ≥ 21 days, for atleast 6 hours per day). It accounts for about 10% of all mechanically ventilated patients. Although these patients represent a smaller proportion of intensive care unit (ICU) patients, they consume substantial ICU resources. We studied etiology, metabolic and clinical profile, complications and outcome of these patients...
October 2015: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27560021/use-of-a-noise-optimized-monoenergetic-algorithm-for-patient-size-independent-selection-of-an-optimal-energy-level-during-dual-energy-ct-of-the-pancreas
#20
Davide Bellini, Sonia Gupta, Juan Carlos Ramirez-Giraldo, Wanyi Fu, Sandra S Stinnett, Bhavik Patel, Achille Mileto, Daniele Marin
PURPOSE: To investigate the impact of a second-generation noise-optimized monoenergetic algorithm on selection of the optimal energy level, image quality, and effect of patient body habitus for dual-energy multidetector computed tomography of the pancreas. MATERIALS AND METHODS: Fifty-nine patients (38 men, 21 women) underwent dual-energy multidetector computed tomography (80/Sn140 kV) in the pancreatic parenchymal phase. Image data sets, at energy levels ranging from 40 to 80 keV (in 5-keV increments), were reconstructed using first-generation and second-generation noise-optimized monoenergetic algorithm...
January 2017: Journal of Computer Assisted Tomography
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