Sajad Sahab Negah, Hadi Aligholi, Zabihollah Khaksar, Hadi Kazemi, Sayed Mostafa Modarres Mousavi, Maryam Safahani, Parastoo Barati Dowom, Ali Gorji
OBJECTIVES: In order to grow cells in a three-dimensional (3D) microenvironment, self-assembling peptides, such as PuraMatrix, have emerged with potential to mimic the extracellular matrix. The aim of the present study was to investigate the influence of the self-assembling peptide on the morphology, survival, proliferation rate, migration potential, and differentiation of human meningioma stem-like cells (hMgSCs). MATERIALS AND METHODS: The efficacy of a novel method for placing hMgSCs in PuraMatrix (the injection approach) was compared to the encapsulation and surface plating methods...
December 2016: Iranian Journal of Basic Medical Sciences