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Thyroid AND reproduction

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https://www.readbyqxmd.com/read/29155610/seasonal-and-sexual-variation-in-metabolism-thermoregulation-and-hormones-in-the-big-brown-bat-eptesicus-fuscus
#1
Christopher S Richardson, Tim Heeren, Thomas H Kunz
In response to seasonal variation in energy availability and thermal environment, physiological and endocrine mechanisms have evolved in temperate zone animals. Seasonal changes in hormone activity affect metabolism, body temperature, and reproductive activity. We examined the seasonal regulatory role of hormones on basal metabolic rate (BMR) and regulatory nonshivering thermogenesis (RNST) in 98 female and 17 male adult Eptesicus fuscus (big brown bat). We measured BMR, RNST, and plasma levels of thyroid hormone (T3), leptin, and cortisol in bats captured in maternity colonies in eastern Massachusetts from May to August (from arousal from the hibernation phase to the prehibernation phase)...
January 2018: Physiological and Biochemical Zoology: PBZ
https://www.readbyqxmd.com/read/29154201/neuroendocrine-disorder-in-chronic-fatigue-syndrome
#2
Slavica Tomic, Snezana Brkic, Dajana Lendak, Daniela Maric, Milica Medic Stojanoska, Aleksandra Novakov Mikic
Background/aim: Neuroendocrine disorders are considered a possible pathogenetic mechanism in chronic fatigue syndrome (CFS). The aim of our study was to determine the function of the hypothalamic-pituitary-adrenal axis (HPA) and thyroid function in women of reproductive age suffering from CFS. Materials and methods: The study included 40 women suffering from CFS and 40 healthy women (15-45 years old). Serum levels of cortisol (0800 and 1800 hours), ACTH, total T4, total T3, and TSH were measured in all subjects...
August 23, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29128804/hexachlorobenzene-as-a-persistent-organic-pollutant-toxicity-and-molecular-mechanism-of-action
#3
REVIEW
Beata Starek-Świechowicz, Bogusława Budziszewska, Andrzej Starek
Hexachlorobenzene (HCB) is an organochlorine pesticide widely distributed in the environment. Chronic exposure of humans to HCB leads to a number of effects, such as triggering of porphyria, microsomal enzyme induction, thyroid dysfunctions, neurological symptoms, and immunological disorders. In animals, HCB induced hepatic porphyria, neurotoxic effects, and toxic effects on the thyroid function, reproductive system, and immune system. HCB as a dioxin-like compound and a weak ligand of the aryl hydrocarbon receptor (AhR) is a hormonal disruptor...
July 1, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29111305/landmark-discoveries-in-elucidating-the-origins-of-the-hypothalamic-pituitary-system-from-the-perspective-of-a-basal-vertebrate-sea-lamprey
#4
REVIEW
Stacia A Sower
The hypothalamic-pituitary (HP) system, which is specific to vertebrates, is considered to be an evolutionary innovation that emerged prior to or during the differentiation of the ancestral jawless vertebrates (agnathans) leading to the neuroendocrine control of many complex functions. Along with hagfish, lampreys represent the oldest lineage of vertebrates, agnathans (jawless fish). This review will highlight our discoveries of the major components of the lamprey HP axis. Generally, gnathostomes (jawed vertebrates) have one or two hypothalamic gonadotropin-releasing hormones (GnRH) while lampreys have three hypothalamic GnRHs...
October 27, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/29109862/comparative-analysis-of-thyroid-function-parameters-in-pregnant-women
#5
Feng Ren, Huan Zhou, Min Chen, Xianqiu Xiao, Xiaoping Rui
The aim of the present study was to investigate the serum levels of free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) during pregnancy and comparative analysis of serum markers levels in non-pregnant women and pregnant women. Pregnant women were divided into four groups according to their gestational age: 8-14, 15-20, 21-36 and ≥37 weeks. Non-pregnant women were divided into three groups according to their age: 20-40, 41-55 and 56-85 years, and women of reproductive age (20-40 years) as control, which match their age and body mass index with pregnant women...
November 2017: Biomedical Reports
https://www.readbyqxmd.com/read/29104009/a-plurality-of-molecular-targets-the-receptor-ecosystem-for-bisphenol-a-bpa
#6
REVIEW
Harry MacKay, Alfonso Abizaid
Bisphenol-A (BPA) is a well-known endocrine disrupting compound (EDC), capable of affecting the normal function and development of the reproductive system, brain, adipose tissue, and more. In spite of these diverse and well characterized effects, there is often comparatively little known about the molecular mechanisms which bring them about. BPA has traditionally been regarded as a primarily estrogenic EDC, and this perspective is often what guides research into the effects of BPA. However, emerging data from in-vitro and in-silico models show that BPA binds with a significant number of hormone receptors, including a number of nuclear and membrane-bound estrogen receptors, androgen receptors, as well as the thyroid hormone receptor, glucocorticoid receptor, and PPARγ...
November 14, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/29102040/preconceptional-antithyroid-peroxidase-antibodies-but-not-thyroid-stimulating-hormone-are-associated-with-decreased-live-birth-rates-in-infertile-women
#7
Aimee Seungdamrong, Anne Z Steiner, Clarisa R Gracia, Richard S Legro, Michael P Diamond, Christos Coutifaris, William D Schlaff, Peter Casson, Gregory M Christman, Randal D Robinson, Hao Huang, Ruben Alvero, Karl R Hansen, Susan Jin, Esther Eisenberg, Heping Zhang, Nanette Santoro
OBJECTIVE: To study whether preconceptual thyroid-stimulating hormone (TSH) and antithyroid peroxidase (TPO) antibodies are associated with poor reproductive outcomes in infertile women. DESIGN: Secondary analysis of data from two multicenter, randomized, controlled trials conducted by the Reproductive Medicine Network of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Multivariable logistic regression analyses were performed to assess the association between preconceptual TSH levels and anti-TPO antibodies...
October 25, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/29082343/change-of-various-characteristics-between-spawning-and-non-spawning-season-in-diploid-and-induced-triploid-far-eastern-catfish-silurus-asotus
#8
Sun Young Lim, Hyun Woo Gil, In-Seok Park
The purpose of this study is to investigate the differences fatty acids and hormonal parameters in the spawning and non-spawning season between the diploid and induced triploid Far Eastern catfish, Silurus asotus. The measured triploids were produced by cold shock for 50 min at 4℃ in May 2014, the spawning season of diploid was in May, and the non-spawning season was designated in January. Estradiol and testosterone and gonadosomatic index of diploid were higher than those of induced triploid in spawning season (P<0...
September 2017: Balsaeng'gwa Saengsig
https://www.readbyqxmd.com/read/29070512/debate-identifying-and-treating-subclinical-thyroid-dysfunction-in-pregnancy-emerging-controversies
#9
Ines I Velasco, Peter Nicholas Taylor
Thyroid hormones are essential for an adequate growth and development of the foetus. In addition to the classical association between maternal hypothyroidism and neurological impairment in the progeny, other adverse reproductive events have been associated with maternal thyroid dysfunction including infertility, miscarriage and preterm delivery. Although all scientific societies endorse the treatment of overt hypothyroidism; the management and/or treatment of subclinical hypothyroidism, hypothyroxinemia or antithyroid antibody-positive women should be considered with caution...
October 25, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29069258/early-menarche-and-teenager-pregnancy-as-risk-factors-for-morbid-obesity-among-reproductive-age-women-a-case-control-study
#10
Amanda Gonçalves Neves, Karina Tamy Kasawara, Ana Carolina Godoy-Miranda, Flávio Hideki Oshika, Elinton Adami Chaim, Fernanda Garanhani Surita
OBJECTIVES: The aim of this study was to evaluate potential risk factors, including non-communicable diseases, for morbid obesity in women between 20 and 49 years of age. METHODS: We performed a case-control study with 110 morbidly obese women and 110 women with adequate weight who were matched by age and with a 1:1 case to control ratio. All women were between 20 to 49 years old and non-menopausal. Possible risk factors were evaluated through a self-report questionnaire assessing socio-demographic, obstetric and gynecological characteristics, presence of non-communicable diseases and habits...
October 2017: Clinics
https://www.readbyqxmd.com/read/29066595/physiological-effects-of-high-altitude-trekking-on-gonadal-thyroid-hormones-and-macrophage-migration-inhibitory-factor-mif-responses-in-young-lowlander-women
#11
Vittore Verratti, Francesca Ietta, Luana Paulesu, Roberta Romagnoli, Ilaria Ceccarelli, Christian Doria, Giorgio Fanò Illic, Camillo Di Giulio, Anna M Aloisi
Altitude hypoxia is often associated with impairment of human reproduction. In this study, hormones and macrophage migration inhibitory factor (MIF, a proinflammatory cytokine with key roles in human reproduction) were determined in seven regularly menstruating, lowlander native women living at sea level participating in 14 days of trekking at moderate and high altitude. Blood and saliva samples were collected from each subject at high altitude (5050 m a.s.l. [above sea level]), and at sea level before and after the expedition...
November 2017: Physiological Reports
https://www.readbyqxmd.com/read/29065468/a-summary-of-new-findings-on-the-biological-effects-of-selenium-in-selected-animal-species-a-critical-review
#12
REVIEW
Bozena Hosnedlova, Marta Kepinska, Sylvie Skalickova, Carlos Fernandez, Branislav Ruttkay-Nedecky, Thembinkosi Donald Malevu, Jiri Sochor, Mojmir Baron, Magdalena Melcova, Jarmila Zidkova, Rene Kizek
Selenium is an essential trace element important for many physiological processes, especially for the functions of immune and reproductive systems, metabolism of thyroid hormones, as well as antioxidant defense. Selenium deficiency is usually manifested by an increased incidence of retention of placenta, metritis, mastitis, aborts, lowering fertility and increased susceptibility to infections. In calves, lambs and kids, the selenium deficiency demonstrates by WMD (white muscle disease), in foals and donkey foals, it is associated with incidence of WMD and yellow fat disease, and in pigs it causes VESD (vitamin E/selenium deficiency) syndrome...
October 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29059580/characteristics-of-peripheral-blood-nk-and-nkt-like-cells-in-euthyroid-and-subclinical-hypothyroid-women-with-thyroid-autoimmunity-experiencing-reproductive-failure
#13
Eva Miko, Matyas Meggyes, Katalin Doba, Nelli Farkas, Barbara Bogar, Aliz Barakonyi, Laszlo Szereday, Julia Szekeres-Bartho, Emese Mezosi
Thyroid autoimmunity (TAI) appears to play a crucial role in female infertility, recurrent pregnancy loss and IVF failure. Thyroid autoantibodies against thyroid peroxidase and thyroglobulin have been shown to represent an independent risk factor for infertility and miscarriage. Moreover, thyroxin hormone administration reduces the risk of obstetrical complications in TAI positive women. The aim of our present study was to investigate the immunological background of female infertility and recurrent pregnancy loss in euthyroid and subclinical hypothyroid women with TAI focusing on innate immunity...
September 28, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/29043757/there-is-no-association-between-the-presence-of-anti-thyroid-antibodies-and-increased-reproductive-loss-in-pregnant-women-after-art-a-systematic-review-and-meta-analysis
#14
REVIEW
Paz Leiva, Juan Enrique Schwarze, Pamela Vasquez, Carolina Ortega, Sonia Villa, Javier Crosby, José Balmaceda, Ricardo Pommer
Women submitted to ART treatments represent a select subgroup of individuals. Several studies have described the relationship between TAI and pregnancy outcomes as a result of ART, with contradictory results. The purpose of this systematic review was to determine the association between TAI and the risk of miscarriage in pregnancies resulting from ART. MEDLINE via PubMed, LILACS and Embase were searched for studies published in peer-reviewed journals from 1999 to 2017. The studies were summarized using the fixed effects model and the Peto's method to calculate RR in order to flesh out the association between TAI and spontaneous abortion...
October 18, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/29028670/cord-blood-bisphenol-a-levels-and-reproductive-and-thyroid-hormone-levels-of-neonates-the-hokkaido-study-on-environment-and-children-s-health
#15
Machiko Minatoya, Seiko Sasaki, Atsuko Araki, Chihiro Miyashita, Sachiko Itoh, Jun Yamamoto, Toru Matsumura, Takahiko Mitsui, Kimihiko Moriya, Kazutoshi Cho, Keita Morioka, Hisanori Minakami, Nobuo Shinohara, Reiko Kishi
BACKGROUND: Bisphenol A (BPA) is widely used and BPA exposure is nearly ubiquitous in developed countries. While animal studies have indicated adverse health effects of prenatal BPA exposure including reproductive dysfunction and thyroid function disruption possibly in a sex-specific manner, findings from epidemiologic studies have not been enough to prove these adverse effects. Given very limited research on human, the aim of this study was to investigate associations between cord blood BPA levels and reproductive and thyroid hormone levels of neonates and whether associations differed by neonate sex...
October 2017: Epidemiology
https://www.readbyqxmd.com/read/28988577/pathophysiology-of-the-effects-of-alcohol-abuse-on-the-endocrine-system
#16
Nadia Rachdaoui, Dipak K Sarkar
Alcohol can permeate virtually every organ and tissue in the body, resulting in tissue injury and organ dysfunction. Considerable evidence indicates that alcohol abuse results in clinical abnormalities of one of the body's most important systems, the endocrine system. This system ensures proper communication between various organs, also interfacing with the immune and nervous systems, and is essential for maintaining a constant internal environment. The endocrine system includes the hypothalamic-pituitary-adrenal axis, the hypothalamic-pituitary-gonadal axis, the hypothalamic-pituitary-thyroid axis, the hypothalamic-pituitary-growth hormone/insulin-like growth factor-1 axis, and the hypothalamic-posterior pituitary axis, as well as other sources of hormones, such as the endocrine pancreas and endocrine adipose tissue...
2017: Alcohol Research: Current Reviews
https://www.readbyqxmd.com/read/28984395/the-cost-of-reproduction-in-women-reproductive-effort-and-oxidative-stress-in-premenopausal-and-postmenopausal-american-women
#17
Anna Ziomkiewicz, Amara Frumkin, Yawei Zhang, Amelia Sancilio, Richard G Bribiescas
OBJECTIVES: Life history theory predicts a trade-off between female investment in reproduction and somatic maintenance, which can result in accelerated senescence. Oxidative stress has been shown to be a causal physiological mechanism for accelerated aging and a possible contributor to this trade-off. We aimed to test the hypothesis for the existence of significant associations between measures of reproductive effort and the level of oxidative stress biomarkers in premenopausal and postmenopausal American women...
October 6, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28980233/molecular-and-neuroendocrine-mechanisms-of-avian-seasonal-reproduction
#18
T Katherine Tamai, Takashi Yoshimura
Animals living outside tropical zones experience seasonal changes in the environment and accordingly, adapt their physiology and behavior in reproduction, molting, and migration. Subtropical birds are excellent models for the study of seasonal reproduction because of their rapid and dramatic response to changes in photoperiod. For example, testicular weight typically changes by more than a 100-fold. In birds, the eyes are not necessary for seasonal reproduction, and light is instead perceived by deep brain photoreceptors...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28975373/the-impact-of-thyroid-hormone-in-seasonal-breeding-has-a-restricted-transcriptional-signature
#19
Didier Lomet, Juliette Cognié, Didier Chesneau, Emeric Dubois, David Hazlerigg, Hugues Dardente
Thyroid hormone (TH) directs seasonal breeding through reciprocal regulation of TH deiodinase (Dio2/Dio3) gene expression in tanycytes in the ependymal zone of the medio-basal hypothalamus (MBH). Thyrotropin secretion by the pars tuberalis (PT) is a major photoperiod-dependent upstream regulator of Dio2/Dio3 gene expression. Long days enhance thyrotropin production, which increases Dio2 expression and suppresses Dio3 expression, thereby heightening TH signaling in the MBH. Short days appear to exert the converse effect...
October 3, 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/28972481/-population-and-cluster-approach-to-assessment-of-reproductive-health-of-women
#20
M Gulzoda, F Khalimova, F Shukurov, A Gulin
The purpose of this study was to explore the possibility of using a population approach to assessing the risk of reproductive health disorders in women of childbearing age. We observed 240 clinically healthy women aged 20 to 43 years, half of them lived in the Middle Black Earth region of Russia, and 120 women lived in Tajikistan. The study identified population differences in women with different ethnic backgrounds and regions of residence according to a set of genetic, hormonal, and immune signs. All women underwent venous blood sampling for the purpose of HLA typing by molecular genetic analysis and determining the range of normative values ​​of hormonal and immune status parameters...
September 2017: Georgian Medical News
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