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https://www.readbyqxmd.com/read/29599999/innovation-for-the-future-of-irish-medtech-industry-retrospective-qualitative-review-of-impact-of-bioinnovate-ireland-s-clinical-fellows
#1
Elizabeth Kate McGloughlin, Paul Anglim, Ivan Keogh, Faisal Sharif
Clinicians have historically been integral in innovating and developing technology in medicine and surgery. In recent years, however, in an increasingly complex healthcare system, a doctor with innovative ideas is often left behind. Transition from idea to bedside now entails significant hurdles, which often go unrecognised at the outset, particularly for first-time innovators. The BioInnnovate Ireland process, based on the Stanford Biodesign Programme (Identify, Invent and Implement), aims to streamline the process of innovation within the MedTech sector...
January 2018: BMJ Innovations
https://www.readbyqxmd.com/read/29587448/development-of-implantable-wireless-sensor-nodes-for-animal-husbandry-and-medtech-innovation
#2
Jian Lu, Lan Zhang, Dapeng Zhang, Sohei Matsumoto, Hiroshi Hiroshima, Ryutaro Maeda, Mizuho Sato, Atsushi Toyoda, Takafumi Gotoh, Nobuhiro Ohkohchi
In this paper, we report the development, evaluation, and application of ultra-small low-power wireless sensor nodes for advancing animal husbandry, as well as for innovation of medical technologies. A radio frequency identification (RFID) chip with hybrid interface and neglectable power consumption was introduced to enable switching of ON/OFF and measurement mode after implantation. A wireless power transmission system with a maximum efficiency of 70% and an access distance of up to 5 cm was developed to allow the sensor node to survive for a duration of several weeks from a few minutes' remote charge...
March 26, 2018: Sensors
https://www.readbyqxmd.com/read/29494804/patient-specific-topographic-anatomy-of-the-deep-circumflex-iliac-artery-flap-comparing-standard-and-modified-computed-tomographic-angiography
#3
Victoria Behrens, Ali Modabber, Christina Loberg, Andreas Herrler, Andreas Prescher, Alireza Ghassemi
PURPOSE: Computed tomographic angiography (CTA) is reported to give insight into patient-specific anatomy of the flap pedicle preoperatively. We compared information available from standard CTA (s-CTA) with that gained by modifying the conventional CTA technique (modified CTA [m-CTA]). Dissected cadavers served as the control group. MATERIALS AND METHODS: We evaluated 16 s-CTA scans (32 deep circumflex iliac arteries [DCIAs]) and 12 m-CTA scans (17 DCIAs) using 3-dimensional software (Vesalius; ps-medtech, Amsterdam, The Netherlands)...
February 26, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29408592/stereotactic-radiofrequency-thermocoagulation-of-hypothalamic-hamartoma-using-robotic-guidance-rosa-coregistered-with-o-arm-guidance-preliminary-technical-note
#4
Vivek Tandon, Poodipedi Sarat Chandra, Ramesh Sharanappa Doddamani, Heri Subianto, Jitin Bajaj, Ajay Garg, Manjari Tripathi
INTRODUCTION: Treatment options for hypothalamic hamartoma (HH) include microvascular surgery, stereotactic radiofrequency thermocoagulation (SRT), laser interstitial thermal therapy, or Gamma Knife surgery. During SRT, thermographic monitoring cannot be performed and therefore highly accurate placement of electrode and confirmation of its position are required. We have used robotic guidance (ROSA) and coregistered it with O-arm for performing ablation of hamartoma. METHODS: Five patients with HH and gelastic seizures underwent SRT...
April 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29243500/designing-medical-technology-for-resilience-integrating-health-economics-and-human-factors-approaches
#5
Simone Borsci, Ijeoma Uchegbu, Peter Buckle, Zhifang Ni, Simon Walne, George B Hanna
The slow adoption of innovation into healthcare calls into question the manner of evidence generation for medical technology. This paper identifies potential reasons for this including a lack of attention to human factors, poor evaluation of economic benefits, lack of understanding of the existing healthcare system and a failure to recognise the need to generate resilient products. Areas covered: Recognising a cross-disciplinary need to enhance evidence generation early in a technology's life cycle, the present paper proposes a new approach that integrates human factors and health economic evaluation as part of a wider systems approach to the design of technology...
January 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29173603/comparison-of-different-automated-office-blood-pressure-measurement-devices-evidence-of-nonequivalence-and-clinical-implications
#6
RANDOMIZED CONTROLLED TRIAL
Félix Rinfret, Lyne Cloutier, Robert Wistaff, Leora M Birnbaum, Nathalie Ng Cheong, Mikhael Laskine, Ghislaine Roederer, Paul Van Nguyen, Michel Bertrand, Remi Rabasa-Lhoret, Robert Dufour, Maxime Lamarre-Cliche
BACKGROUND: Automated office blood pressure (AOBP) measuring devices are increasingly recommended as preferred blood pressure (BP) diagnostic tools, but it is unclear how they compare and how clinical environments impact their performance. METHODS: This prospective randomized factorial parallel 4-group study compared BP estimates by BpTRU (VSM MedTech, Vancouver, BC, Canada) and Omron HEM 907 (Omron Healthcare, Kyoto, Japan) devices in closed vs open areas. Patients diagnosed with hypertension were recruited during office visits...
December 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29155063/robotic-guided-bihippocampal-and-biparahippocampal-depth-placement-for-responsive-neurostimulation-in-bitemporal-lobe-epilepsy
#7
Pratik Rohatgi, Ryan J Jafrani, Nicholas J Brandmeir, Frank G Gilliam, Tiffany L Fisher, Michael D Sather
BACKGROUND: Patients with bitemporal lobe epilepsy are generally not considered for surgical resection. Fortunately, responsive neurostimulation provides another avenue for the management of this challenging disease process. In conjunction with our epileptologist, we consider responsive neurostimulation for patients who have clinical features of temporal lobe epilepsy without clear localization on imaging and stereoelectroencephalography. METHODS: Here we describe our technique for implanting a responsive neurostimulator (NeuroPace, NeuroPace Inc...
March 2018: World Neurosurgery
https://www.readbyqxmd.com/read/28756273/back-to-the-future-circuit-testing-ts-ocd
#8
Frank H Burton
A decade before the rise of optogenetics, the first behavioral "circuit-test" - transgenically modulating the output of a genetically-specified brain circuit element to examine its effect on behavior - was performed. The behaviors emulated in those mice were comorbid tics and compulsions, elicited by a gene borrowed from cholera bacteria and tailored to intracellularly neuropotentiate glutamatergic somatosensory cortical and limbic output neurons of cortico/amygdalo-striato-thalamo-cortical (CSTC) loop circuits...
July 26, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28628601/the-damage-control-surgery-in-austere-environments-research-group-dcsaerg-a-dynamic-program-to-facilitate-real-time-telementoring-telediagnosis-to-address-exsanguination-in-extreme-and-austere-environments
#9
Andrew W Kirkpatrick, Jessica L McKee, Paul B McBeth, Chad G Ball, Anthony LaPorta, Timothy Broderick, Tim Leslie, David King, Heather E Wright Beatty, Jocelyn Keillor, Homer Tien
Hemorrhage is the most preventable cause of posttraumatic death. Many cases are potentially anatomically salvageable, yet remain lethal without logistics or trained personnel to deliver diagnosis or resuscitative surgery in austere environments. Revolutions in technology for remote mentoring of ultrasound and surgery may enhance capabilities to utilize the skill sets of non-physicians. Thus, our research collaborative explored remote mentoring to empower non-physicians to address junctional and torso hemorrhage control in austere environments...
July 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28438270/innovation-within-a-national-health-care-system
#10
Antony Young
Tony is a practicing frontline National Health Service surgeon and director of medical innovation at Anglia Ruskin University and has founded 4 medical-technology start-ups. He has also cofounded the £500 million Anglia Ruskin MedTech Campus, which will become one of the world's largest health innovation spaces. In 2014, he was appointed as national clinical director for innovation at National Health Service England and in February 2016 became the first national clinical lead for innovation. In this role, he provides clinical leadership and support in delivering improved health outcomes in England, drives the uptake of proven innovations across the National Health Service, promotes economic growth through innovation, and helps make the National Health Service the go-to place on the planet for medical innovation...
May 2017: Surgery
https://www.readbyqxmd.com/read/28383477/the-damage-control-surgery-in-austere-environments-research-group-dcsaerg-a-dynamic-program-to-facilitate-real-time-tele-mentoring-tele-diagnosis-to-address-exsanguination-in-extreme-and-austere-environments
#11
Andrew W Kirkpatrick, Jessica McKee, Paul B McBeth, Chad G Ball, Anthony LaPorta, Timothy Broderick, Tim Leslie, David King, Heather Wright-Beatty, Jocelyn Keillor, Homer Tien
Hemorrhage is the most preventable cause of post-traumatic death. Many cases are potentially anatomically salvageable, yet remain lethal without logistics or trained personnel to deliver diagnosis or Resuscitative-surgery in austere-environments. Revolutions in technology for remote-mentoring of ultrasound and surgery may enhance capabilities to utilize the skill-sets of non-physicians. Thus, our Research-Collaborative explored remote-mentoring to empower non-physicians to address junctional and torso hemorrhage-control in Austere-environments...
April 5, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28361610/an-industry-update-the-latest-developments-in-therapeutic-delivery
#12
Oliver C Steinbach
The present industry update covers the period 1-31 January 2017, with information sourced from company press releases, regulatory and patent agencies as well as the scientific literature. With a new year come new resolutions, annual operation plans but also reports and outlooks for the years(s) to come. A number of the latter have been published in January forecasting various spaces in drug delivery (Market and Research). Also a number of financing deals were closed being fresh into the year such as Ossianix and Ocular Therapeutix and contract manufacturers will show their offerings at the 2017 MD&M West Medtech event (Lubrizol, Trelleborg)...
March 2017: Therapeutic Delivery
https://www.readbyqxmd.com/read/28202496/the-new-medtech-europe-directive-implications-for-educational-activities-in-pathology-and-laboratory-medicine
#13
EDITORIAL
Tahir S Pillay
No abstract text is available yet for this article.
March 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/27943178/early-experience-with-the-venus-p%C3%A2-valve-for-percutaneous-pulmonary-valve-implantation-in-native-outflow-tract
#14
F Garay, X Pan, Y J Zhang, C Wang, D Springmuller
INTRODUCTION: The Venus p‑valve (MedTech, Shanghai, China) is a self-expanding percutaneous heart valve designed to be implanted in a native patched right ventricle outflow tract. The worldwide clinical experience with this valve is just beginning and the results have so far been encouraging. We present our initial early experience implanting the Venus p‑valve in the native right ventricle outflow tract of patients with Tetralogy of Fallot repaired with a transannular patch. METHODS: In 10 selected patients a procedure for percutaneous pulmonary valve implantation was performed using the Venus p‑valve...
February 2017: Netherlands Heart Journal
https://www.readbyqxmd.com/read/27753920/os-04-04-antihypertensive-effect-of-milk-derivative-tripeptides-randomized-double-blind-placebo-controlled-study-on-the-effects-of-grana-padano-cheese-dop-in-hypertensive-patients
#15
Giuseppe Crippa, Dorjan Zabzuni, Elena Bravi, Filippo Rossi
OBJECTIVE: Present data refers to a randomized, double-blind, placebo-controlled, cross-over study in which 30 mild-moderate hypertensive patients, received a dietary integration with Grana Padano DOP cheese to evaluate blood pressure (BP) changes.Cow-milk fermentation induced by Lactobacillus helveticus produces peptides with sustained ACE inhibitory activity, mainly dues to 2 tripeptides (valyl-prolyl-proline and isoleucil-prolyl-proline) that have shown to lower blood pressure (BP) in experimental animals and in humans...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27690660/stereotactic-robot-assisted-mri-guided-laser-thermal-ablation-of-radiation-necrosis-in-the-posterior-cranial-fossa-technical-note
#16
Alvin Y Chan, Diem Kieu T Tran, Amandip S Gill, Frank P K Hsu, Sumeet Vadera
Laser interstitial thermal therapy (LITT) is a minimally invasive procedure used to treat a variety of intracranial lesions. Utilization of robotic assistance with stereotactic procedures has gained attention due to potential for advantages over conventional techniques. The authors report the first case in which robot-assisted MRI-guided LITT was used to treat radiation necrosis in the posterior fossa, specifically within the cerebellar peduncle. The use of a stereotactic robot allowed the surgeon to perform LITT using a trajectory that would be extremely difficult with conventional arc-based techniques...
October 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27649314/evaluation-of-the-rosa%C3%A2-spine-robot-for-minimally-invasive-surgical-procedures
#17
M Lefranc, J Peltier
The ROSA® robot (Medtech, Montpellier, France) is a new medical device designed to assist the surgeon during minimally invasive spine procedures. The device comprises a patient-side cart (bearing the robotic arm and a workstation) and an optical navigation camera. The ROSA® Spine robot enables accurate pedicle screw placement. Thanks to its robotic arm and navigation abilities, the robot monitors movements of the spine throughout the entire surgical procedure and thus enables accurate, safe arthrodesis for the treatment of degenerative lumbar disc diseases, exactly as planned by the surgeon...
October 2016: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/27643305/os-04-04-antihypertensive-effect-of-milk-derivative-tripeptides-randomized-double-blind-placebo-controlled-study-on-the-effects-of-grana-padano-cheese-dop-in-hypertensive-patients
#18
Giuseppe Crippa, Dorjan Zabzuni, Elena Bravi, Filippo Rossi
OBJECTIVE: Present data refers to a randomized, double-blind, placebo-controlled, cross-over study in which 30 mild-moderate hypertensive patients, received a dietary integration with Grana Padano DOP cheese to evaluate blood pressure (BP) changes.Cow-milk fermentation induced by Lactobacillus helveticus produces peptides with sustained ACE inhibitory activity, mainly dues to 2 tripeptides (valyl-prolyl-proline and isoleucil-prolyl-proline) that have shown to lower blood pressure (BP) in experimental animals and in humans...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27568817/easy-faster-and-not-bloody-providers-perceptions-on-prepex%C3%A2-in-south-africa
#19
Minja Milovanovic, Noah Taruberekera, Karin Hatzold, Neil Martinson, Limakatso Lebina
PrePex™ (Circ MedTech Ltd., Tortola, British Virgin Islands) devices are being evaluated in several countries for scale-up of medical male circumcision (MMC) as an HIV prevention intervention. Health care workers' perceptions should be considered prior to scale-up. A cross-sectional open-ended questionnaire was administered to health care workers from nine MMC programs in South Africa that provided either PrePex™ and surgical circumcision (mixed sites) or surgical circumcision only (surgery-only sites)...
November 2016: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/26925395/who-owns-the-data-open-data-for-healthcare
#20
REVIEW
Patty Kostkova, Helen Brewer, Simon de Lusignan, Edward Fottrell, Ben Goldacre, Graham Hart, Phil Koczan, Peter Knight, Corinne Marsolier, Rachel A McKendry, Emma Ross, Angela Sasse, Ralph Sullivan, Sarah Chaytor, Olivia Stevenson, Raquel Velho, John Tooke
Research on large shared medical datasets and data-driven research are gaining fast momentum and provide major opportunities for improving health systems as well as individual care. Such open data can shed light on the causes of disease and effects of treatment, including adverse reactions side-effects of treatments, while also facilitating analyses tailored to an individual's characteristics, known as personalized or "stratified medicine." Developments, such as crowdsourcing, participatory surveillance, and individuals pledging to become "data donors" and the "quantified self" movement (where citizens share data through mobile device-connected technologies), have great potential to contribute to our knowledge of disease, improving diagnostics, and delivery of -healthcare and treatment...
2016: Frontiers in Public Health
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