Yu Jun Wong, Vincent L Chen, Asim Abdulhamid, Giulia Tosetti, Huttakan Navadurong, Apichat Kaewdech, Jessica Cristiu, Michael Song, Pooja Devan, Kai Le Ashley Tiong, Jean Ee Neo, Thaninee Prasoppokakorn, Pimsiri Sripongpun, Catherine Ann Malcolm Stedman, Sombat Treeprasertsuk, Massimo Primignani, Jing Hieng Ngu, Juan G Abraldes
INTRODUCTION: The utility of serial liver stiffness measurements (LSM) to predict decompensation in compensated advanced chronic liver disease (cACLD) patients remains unclear. We aimed to validate whether comparing serial LSM is superior to using the current LSM to predict liver-related events (LRE) in cACLD patients. METHODS: In this retrospective analysis of an international registry, cACLD patients with serial LSM were followed up until index LRE. We compared the performance of both the dynamic LSM changes and the current LSM (LSMc ) in predicting LRE using Cox-regression analysis, considering time zero of follow-up as the date of LSMc...
April 17, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases