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https://www.readbyqxmd.com/read/29145541/variations-in-adipor1-but-not-adipor2-are-associated-with-hypertriglyceridemia-and-diabetes-in-an-admixed-latin-american-population
#1
Gustavo Gustavo Mora-García, María S Ruiz-Díaz, Fabian Espitia-Almeida, Doris Gómez-Camargo
BACKGROUND: Adiponectin is a hormone secreted by adipose tissue. It regulates glycolysis and lipolysis and is involved in the pathophysiology of diabetes and related disorders. Its activity is mainly mediated by the transmembrane receptors AdipoR1 and AdipoR2, which are encoded by ADIPOR1 (1q32.1) and ADIPOR2 (12p13.33) genes, respectively. In genetic association studies, single nucleotide polymorphisms (SNPs) in or near these genes have been associated with metabolic alterations. However, these relationships are still controversial...
July 2017: Review of Diabetic Studies: RDS
https://www.readbyqxmd.com/read/29145355/disparities-in-state-specific-adult-fruit-and-vegetable-consumption-united-states-2015
#2
Seung Hee Lee-Kwan, Latetia V Moore, Heidi M Blanck, Diane M Harris, Deb Galuska
The 2015-2020 Dietary Guidelines for Americans recommend that Americans consume more fruits and vegetables as part of an overall dietary pattern to reduce the risk for diet-related chronic diseases such as cardiovascular disease, type 2 diabetes, some cancers, and obesity (1). Adults should consume 1.5-2.0 cup equivalents of fruits and 2.0-3.0 cups of vegetables per day.* Overall, few adults in each state met intake recommendations according to 2013 Behavioral Risk Factor Surveillance System (BRFSS) data; however, sociodemographic characteristics known to be associated with fruit and vegetable consumption were not examined (2)...
November 17, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29142003/disparities-in-environmental-exposures-to-endocrine-disrupting-chemicals-and-diabetes-risk-in-vulnerable-populations
#3
Daniel Ruiz, Marisol Becerra, Jyotsna S Jagai, Kerry Ard, Robert M Sargis
Burgeoning epidemiological, animal, and cellular data link environmental endocrine-disrupting chemicals (EDCs) to metabolic dysfunction. Disproportionate exposure to diabetes-associated EDCs may be an underappreciated contributor to disparities in metabolic disease risk. The burden of diabetes is not uniformly borne by American society; rather, this disease disproportionately affects certain populations, including African Americans, Latinos, and low-income individuals. The purpose of this study was to review the evidence linking unequal exposures to EDCs with racial, ethnic, and socioeconomic diabetes disparities in the U...
November 15, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29141994/type-ii-diabetes-and-incidence-of-estrogen-receptor-negative-breast-cancer-in-african-american-women
#4
Julie R Palmer, Nelsy Castro-Webb, Kimberly Bertrand, Traci N Bethea, Gerald V Denis
White women with type II diabetes (T2D) have an estimated 20% increased risk of developing breast cancer. Little is known about associations by breast cancer subtype or among African American (AA) women, who are disproportionately affected by T2D and estrogen receptor negative (ER-) breast cancer. We assessed the relation of T2D to incidence of ER- and ER+ breast cancer in data from the Black Women's Health Study, a prospective cohort of AA women enrolled in 1995 and followed biennially. During 847,934 person-years of follow-up, there were 1,851 incident invasive breast cancers, including 914 ER+ and 468 ER- cases...
November 15, 2017: Cancer Research
https://www.readbyqxmd.com/read/29140900/associations-between-bmi-change-and-cardiometabolic-risk-in-retired-football-players
#5
Eric T Trexler, Abbie E Smith-Ryan, J D DeFreese, Stephen W Marshall, Kevin M Guskiewicz, Zachary Y Kerr
PURPOSE: Elevated rates of cardiometabolic diseases have been observed in former American football players. The current study sought to determine if change in body mass index (ΔBMI) following retirement influences the prevalence of coronary heart disease (CHD), diabetes, or high blood pressure (HBP) in former professional football players. METHODS: Retired professional football players (n=3,729) were sent a survey with questions regarding health status, playing history, and demographic information...
November 14, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29139301/design-of-a-24-week-trial-of-empagliflozin-once-daily-in-hypertensive-black-african-american-patients-with-type-2-diabetes-mellitus
#6
Keith C Ferdinand, Leo Seman, Afshin Salsali
OBJECTIVE: Black/African American patients have higher prevalence of type 2 diabetes mellitus (T2DM), diabetes-related complications, and hypertension, but they are often underrepresented in clinical trials. The sodium-glucose co-transporter 2 inhibitor, empagliflozin, was associated with significant improvements in glucose control (via hemoglobin [Hb] A1c) and reductions in blood pressure (BP; via office and ambulatory BP monitoring) in a primarily white population with T2DM and hypertension...
November 15, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29138622/antimicrobial-efficacy-of-penicillium-amestolkiae-elv609-extract-treated-cotton-fabric-for-diabetic-wound-care
#7
Nur Amiera Syuhada Binti Rozman, Nurhanis Syafiqah Binti Mohd Nor Hamin, Leong Chean Ring, Tan Wen Nee, Mahfuzah Binti Mustapha, Tong Woei Yenn
Diabetes mellitus is a chronic disorder which affects millions of population worldwide. Global estimates published in 2010 reported the world diabetic prevalence as 6.4%, affecting 285 million adults. Foot ulceration and wound infection are major forms of disabilities arising from diabetic diseases. This study was aimed to develop a natural antimicrobial finishing on medical grade textile that meets American Association of Textiles Chemists and Colorists (AATCC) standard. The textile samples were finished with the ethanolic extract of Penicillium amestolkiae elv609, an endophytic fungus isolated from Orthosiphon stamineus Benth (common name: cat's whiskers)...
September 2017: Mycobiology
https://www.readbyqxmd.com/read/29138245/clinical-impact-of-diabetes-mellitus-on-outcomes-after-transcatheter-aortic-valve-replacement-insights-from-the-society-of-thoracic-surgeons-american-college-of-cardiology-transcatheter-valve-therapy-registry
#8
Yigal Abramowitz, Sreekanth Vemulapalli, Tarun Chakravarty, Zhuokai Li, Samir Kapadia, David Holmes, Roland A Matsouaka, Alice Wang, Wen Cheng, James S Forrester, Richard Smalling, Vinod Thourani, Michael Mack, Martin Leon, Raj R Makkar
BACKGROUND: Diabetes mellitus (DM) adversely affects morbidity and mortality for cardiovascular diseases and procedures. Data evaluating the outcomes of transcatheter aortic valve replacement (TAVR) in diabetic patients are limited by small sample size and contradictory results. We aimed to establish the magnitude of risk and the incremental influence of insulin dependency by examining short- and long-term adverse outcomes according to DM status and therapy in the world's largest TAVR registry...
November 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29136732/-prognosis-factors-for-the-perineal-incision-complications-after-abdominoperineal-resection-for-low-rectal-cancer
#9
S Luo, J W Liang, H T Zhou, W Pei, Z X Zhou, Q Liu, X S Wang
Objective: To evaluate the prognosis factors affecting perineal incision complications after abdominoperineal resection (APR) for the low rectal cancer. Methods: This was a retrospective analysis of 151 consecutive patients with low rectal cancer undergoing APR between January and December 2013 at Department of Colorectal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. The patients were comprised of 95 males and 56 females. The mean age of the patients was (57...
November 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29135987/determining-the-optimal-screening-interval-for-type-2-diabetes-mellitus-using-a-risk-prediction-model
#10
Andrei Brateanu, Thomas Barwacz, Lei Kou, Sihe Wang, Anita D Misra-Hebert, Bo Hu, Abhishek Deshpande, Nana Kobaivanova, Michael B Rothberg
BACKGROUND: Progression to diabetes mellitus (DM) is variable and the screening time interval not well defined. The American Diabetes Association and US Preventive Services Task Force suggest screening every 3 years, but evidence is limited. The objective of the study was to develop a model to predict the probability of developing DM and suggest a risk-based screening interval. METHODS: We included non-diabetic adult patients screened for DM in the Cleveland Clinic Health System if they had at least two measurements of glycated hemoglobin (HbA1c), an initial one less than 6...
2017: PloS One
https://www.readbyqxmd.com/read/29135663/serum-fructosamine-a-simple-and-inexpensive-test-for-assessing-preoperative-glycemic-control
#11
Noam Shohat, Majd Tarabichi, Eric H Tischler, Serge Jabbour, Javad Parvizi
BACKGROUND: Although the medical community acknowledges the importance of preoperative glycemic control, the literature is inconclusive and the proper metric for assessment of glycemic control remains unclear. Serum fructosamine reflects the mean glycemic control in a shorter time period compared with glycated hemoglobin (HbA1c). Our aim was to examine its role in predicting adverse outcomes following total joint arthroplasty. METHODS: Between 2012 and 2013, we screened all patients undergoing total joint arthroplasty preoperatively using serum HbA1c, fructosamine, and blood glucose levels...
November 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29132429/characterization-of-skin-function-associated-with-obesity-and-specific-correlation-to-local-systemic-parameters-in-american-women
#12
Shinobu Mori, Akiko Shiraishi, Karen Epplen, Desiree Butcher, Daiki Murase, Yuka Yasuda, Takatoshi Murase
BACKGROUND: Obesity is considered problematic not only as a major cause of diabetes, hypertension, and dyslipidemia, but also as a risk of intractable dermatosis; however influence of obesity on skin function has not been clarified. To clarify the mechanism of obesity-associated skin disorders, we aimed to characterize the skin function of subjects with obesity, and identify possible influencing factors. METHODS: Complex analyses including instrumental measurement, biochemical and lipidomics were performed for facial skin and physical evaluation in 93 Caucasian women with obesity (OB) and non-obesity (NOB)...
November 13, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29124050/association-between-healthy-eating-index-2010-and-fetuin-a-levels-in-patients-with-type-2-diabetes-a-case-control-study
#13
Farzad Roshanzamir, Maryam Miraghajani, Marjan Mansourian, Reza Ghiasvand, Seyyed Morteza Safavi
The Healthy Eating Index-2010 (HEI-2010) assesses compliance with the 2010 Dietary Guidelines for Americans. Studies suggest that adherence to the HEI-2010 is related to lower the risk of type 2 diabetes (T2D). Fetuin-A, a novel biomarker for T2D, may play a linking role in the inverse association between HEI-2010 and T2D. Thus, a case-control analysis involving 107 patients with T2D and107 healthy subjects was conducted to determine the association between HEI-2010 and serum fetuin-A levels. The results of simple regression analysis showed that fetuin-A levels were positively associated with full name of body mass index (BMI) (p < 0...
October 2017: Clinical Nutrition Research
https://www.readbyqxmd.com/read/29122528/safety-of-open-ventral-hernia-repair-in-high-risk-patients-with-metabolic-syndrome-a-multi-institutional-analysis-of-39-118-cases
#14
Dmitry Zavlin, Kevin T Jubbal, Jeffrey L Van Eps, Barbara L Bass, Warren A Ellsworth, Anthony Echo, Jeffrey D Friedman, Brian J Dunkin
BACKGROUND: Metabolic syndrome (MetS) entails the simultaneous presence of a constellation of dangerous risk factors including obesity, diabetes, hypertension, and dyslipidemia. The prevalence of MetS in Western society continues to rise and implies an elevated risk for surgical complications and/or poor surgical outcomes within the affected population. OBJECTIVE: To assess the risks and outcomes of multi-morbid patients with MetS undergoing open ventral hernia repair...
September 22, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29117273/coronary-artery-calcium-score-for-long-term-risk-classification-in-individuals-with-type-2-diabetes-and-metabolic-syndrome-from-the-multi-ethnic-study-of-atherosclerosis
#15
Shaista Malik, Yanglu Zhao, Matthew Budoff, Khurram Nasir, Roger S Blumenthal, Alain G Bertoni, Nathan D Wong
Importance: Although the risk of type 2 diabetes is considered to be equivalent to coronary heart disease (CHD) risk, there is considerable heterogeneity among individuals for CHD and atherosclerotic cardiovascular disease (ASCVD) risk. It is not known whether coronary artery calcium (CAC) assessment at baseline in individuals with established metabolic syndrome (MetS) or diabetes identifies CHD and ASCVD prognostic indicators during a long follow-up period. Objective: To compare improvement in long-term prognostication of incident CHD and ASCVD using CAC scores among those with diabetes, MetS, or neither condition...
November 8, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29116690/an-open-letter-to-the-american-diabetes-association-board-of-directors-special-commentary
#16
Enoch Huang, Jayesh Shah, Debbie Pestell, Jacek Kot, Daniel Mathieu, David Smart, Pasquale Longobardi, Tarun Sahni, Fabrício Valandro Rech, Magnus Löndahl, Mahito Kawashima, Gregory Weir
No abstract text is available yet for this article.
2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29116568/microaggressions-diabetes-distress-and-self-care-behaviors-in-a-sample-of-american-indian-adults-with-type-2-diabetes
#17
Kelley J Sittner, Brenna L Greenfield, Melissa L Walls
American Indian/Alaska Native people experience the highest age-adjusted prevalence of type 2 diabetes of any racial group in the United States, as well as high rates of related health problems. Chronic stressors such as perceived discrimination are important contributors to these persistent health disparities. The current study used structural equation modeling to examine the relationships between racial microaggressions, diabetes distress, and self-care behaviors (diet and exercise) in a sample of 192 American Indians with type 2 diabetes from the northern United States...
November 7, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29114388/epistatic-interactions-between-mutations-of-taci-tnfrsf13b-and-tcf3-result-in-a-severe-primary-immunodeficiency-disorder-and-systemic-lupus-erythematosus
#18
Rohan Ameratunga, Wikke Koopmans, See-Tarn Woon, Euphemia Leung, Klaus Lehnert, Charlotte A Slade, Jessica C Tempany, Anselm Enders, Richard Steele, Peter Browett, Philip D Hodgkin, Vanessa L Bryant
Common variable immunodeficiency disorders (CVID) are a group of primary immunodeficiencies where monogenetic causes account for only a fraction of cases. On this evidence, CVID is potentially polygenic and epistatic although there are, as yet, no examples to support this hypothesis. We have identified a non-consanguineous family, who carry the C104R (c.310T>C) mutation of the Transmembrane Activator Calcium-modulator and cyclophilin ligand Interactor (TACI, TNFRSF13B) gene. Variants in TNFRSF13B/TACI are identified in up to 10% of CVID patients, and are associated with, but not solely causative of CVID...
October 2017: Clinical & Translational Immunology
https://www.readbyqxmd.com/read/29113983/fgf23-concentration-and-apol1-genotype-are-novel-predictors-of-mortality-in-african-americans-with-type-2-diabetes
#19
Gary C Chan, Jasmin Divers, Gregory B Russell, Carl D Langefeld, Lynne E Wagenknecht, Fang-Chi Hsu, Jianzhao Xu, S Carrie Smith, Nicholette D Palmer, Pamela J Hicks, Donald W Bowden, Thomas C Register, Lijun Ma, J Jeffrey Carr, Barry I Freedman
OBJECTIVE: Cardiovascular and renal complications contribute to higher mortality in patients with diabetes. We assessed novel and conventional predictors of mortality in African American-Diabetes Heart Study participants. RESEARCH DESIGN AND METHODS: Associations between mortality and subclinical atherosclerosis, urine albumin-to-creatinine ratio (UACR), estimated glomerular filtration rate (eGFR), plasma fibroblast growth factor 23 (FGF23) concentration, African ancestry proportion, and apolipoprotein L1 genotypes (APOL1) were assessed in 513 African Americans with type 2 diabetes; analyses were performed using Cox proportional hazards models...
November 7, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29109616/good-to-know-information-from-the-american-diabetes-association-for-people-with-diabetes
#20
(no author information available yet)
No abstract text is available yet for this article.
October 2017: Clinical Diabetes: a Publication of the American Diabetes Association
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