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Angiofibroma

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https://www.readbyqxmd.com/read/29325251/-extrapleural-solitary-fibrous-tumor-with-uncommon-histology-a-clinicopathologic-analysis-of-7-cases
#1
M Zhao, Z R Yang, Y B Wang, Y Chen, G W Qi, Y J Yan, W J Xu, G Q Ru, X L He
Objective: To investigate the clinicopathologic characteristics, immunophenotypes, and differential diagnostic features of extra-pleural solitary fibrous tumor (SFT) with uncommon histology. Methods: Seven cases of extra-pleural SFT with uncommon histology were collected during January 2015 and December 2016 in Zhejiang Provincal People's Hospital; the clinical and radiologic features, histomorphology, immunophenotype and prognosis were analyzed. EnVision method was used for immunohistochemical staining of STAT6, CD34 and other differential diagnosis associated markers...
January 8, 2018: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/29283151/unusual-intraconal-localization-of-orbital-giant-cell-angiofibroma
#2
Meryem Altin Ekin, Seyda Karadeniz Ugurlu, Fulya Cakalagaoglu
Giant cell angiofibroma (GCA) is a recently reported rare soft-tissue tumor that can develop in various sites including orbit. Orbital GCAs were mainly located in the eyelid or extraconal regions such as lacrimal gland and conjunctiva. We report an atypical case of a GCA arising in the intraconal area of the orbit in a 65-year-old male patient. The tumor was excised in total by lateral orbitotomy. Histological and immunohistochemical features were consistent with the diagnosis of GCA. No recurrence was observed during the follow-up of over 2 years...
January 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29258863/fibrous-cephalic-plaques-in-tuberous-sclerosis-complex
#3
Oyetewa Oyerinde, Danielle Buccine, Alison Treichel, Claire Hong, Chyi-Chia Richard Lee, Joel Moss, Thomas N Darling
BACKGROUND: Fibrous cephalic plaques (FCPs) stereotypically develop on the forehead of tuberous sclerosis complex (TSC) patients. They constitute a major feature for TSC diagnosis, and may present before other TSC-related cutaneous hamartomas. OBJECTIVE: To describe the clinical characteristics of FCPs in TSC. METHODS: 113 patients with TSC were enrolled in an observational cohort study. Retrospective analysis of medical records and skin photography was performed...
December 16, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29249250/-what-s-new-in-pediatric-dermatology
#4
C Chiaverini
The year 2017 in pediatric dermatology was marked by several consensus recommendations and meta analyzes on childhood psoriasis, atopic dermatitis or PHACE syndrome, case series on the role of anti-JAK treatment in adolescent with alopecia areata, sirolimus for vascular malformations, ivermectine for rosacea, inhibitors of MEK for type 1 neurofibromatosis or on the side effects of the oral isotretinoin for acne or propranolol for immature hemangioma. Only few randomized controlled studies have been published on the interest of adalimumab in the treatment of psoriasis or topical sirolimus for angiofibroma in tuberous sclerosis complex for example...
December 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29224039/state-of-the-art-lasers-and-light-treatments-for-vascular-lesions-from-red-faces-to-vascular-malformations
#5
Manuel Valdebran, Brent Martin, Kristen M Kelly
Notable milestones in the treatment of vascular lesions have been achieved over the past century. Many cutaneous vascular lesions can be successfully treated with lightbased devices. In this review, we will discuss the treatment of port-wine birthmarks, lymphatic malformations, infantile hemangiomas, rosacea, venous lakes, pyogenic granulomas, cherry angiomas, and angiofibromas using lasers, total reflection amplification of spontaneous emission of radiation, intense pulsed light, and photodynamic therapy. In addition, for several of these diagnoses, we will review medical therapies that can be combined with light-based devices to provide enhanced results...
December 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29184811/dermatologic-manifestations-of-endocrine-disorders
#6
REVIEW
Michael Lause, Alisha Kamboj, Esteban Fernandez Faith
The skin serves as a window for clinicians to understand, diagnose, and monitor endocrine disease. Dermatologic manifestations of endocrinopathies contribute significantly to an individual's health and quality of life. In this review, we outline various disorders of the hypothalamic-pituitary axis, thyroid gland, pancreas, adrenal gland, and androgen axis as well as hereditary endocrine syndromes. In acromegaly, glycosaminoglycan deposition contributes to a thickening of skin and soft tissue, which manifests as coarsening and enlargement of facial and acral structures...
October 2017: Translational pediatrics
https://www.readbyqxmd.com/read/29143693/a-rare-case-of-extra-nasopharyngeal-angiofibroma-of-the-septum-in-a-female-child
#7
G B Singh, S Shukla, P Kumari, I Shukla
BACKGROUND: Extra-nasopharyngeal angiofibroma is a rare but distinct clinical entity, different from juvenile angiofibroma. METHODS: This clinical record elucidates the only case of extra-nasopharyngeal angiofibroma arising from the septum in a female child, who presented with epistaxis. RESULTS: The histopathological diagnosis was confirmed by immunohistochemistry, and the case was managed surgically with no recurrence. CONCLUSION: In a female paediatric patient presenting with epistaxis, extra-nasopharyngeal angiofibroma (of the inferior turbinate) is a rare albeit important differential diagnosis, as it challenges the hormonal theory of angiofibroma aetiopathogenesis...
November 16, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/29130560/patterns-of-vascularization-and-surgical-morbidity-in-juvenile-nasopharyngeal-angiofibroma-a-case-series-systematic-review-and-meta-analysis
#8
Jonathan B Overdevest, Matthew R Amans, Peter Zaki, Steven D Pletcher, Ivan H El-Sayed
BACKGROUND: Vascular patterns of juvenile nasopharyngeal angiofibroma (JNA) are poorly defined. We performed both institutional and systematic literature reviews to characterize the relationship between arterial supply patterns of JNA with intraoperative blood loss and tumor recurrence. METHODS: A retrospective review of 26 patients with JNA treated at our institution from 1995 to 2015 with available angiograms, and systematic reviews and meta-analyses of 828 JNA cases undergoing angiographic embolization published between 1995 and 2015 were completed per Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines...
November 11, 2017: Head & Neck
https://www.readbyqxmd.com/read/29118545/imaging-modalities-for-an-uncommon-inguinal-scrotal-pathology-a-case-report-and-literature-review
#9
Koo Hao Chun, Fam Xeng Inn, Erica Yee Hing, Goh Eng Hong
Inguinal scrotal swelling is a common presentation to surgical clinic with various differential diagnoses. In most circumstances, a good clinical assessment is sufficient to identify the diagnosis. Imaging is necessary when diagnostic difficulty was encountered. The choice of imaging study could affect the management and outcome. A 60-year-old male presented with an enlarging right inguinal scrotal swelling for 5 years. Clinical examination showed a swelling extended from the right inguinal region down to the right scrotum, firm, not reducible, and not separable from the right testis...
October 2017: Urology Annals
https://www.readbyqxmd.com/read/29114314/endoscopic-three-surgeon-six-handed-transorbital-transnasal-technique-for-excision-of-juvenile-nasopharygeal-angiofibroma-new-frontier-explored
#10
Trichy Narayanan Janakiram, Palak Parekh, Hanish Haneefa, Sivaswamy Karthik Prasad
Endoscopic endonasal transorbital approach has been described for the removal of orbital lesions located anteromedially in temporal fossa. The same has been observed to be a versatile approach to the anterior and middle cranial fossa only in laboratory studies. This is the first clinical report of combined transorbital transnasal endoscopic approach to the cavernous sinus, superior orbital fissure, and middle cranial fossa in a case of recurrent nasopharyngeal angiofibroma using the three-surgeon six-handed technique...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29106748/solitary-fibrous-tumor-of-the-female-genital-tract-a-clinicopathologic-analysis-of-25-cases
#11
Eric J Yang, Brooke E Howitt, Christopher Dm Fletcher, Marisa R Nucci
AIMS: Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm of fibroblastic origin, first described as a tumor of the pleura and now well established at extrapleural sites. However, SFT in the female genital tract is rare and therefore not fully characterized. MATERIAL AND RESULTS: We describe a series of 25 SFTs arising throughout the gynecologic tract, including vulva (14 cases), vagina (1), cervix (1), uterus (6), ovary (2) and fallopian tube (1)...
November 6, 2017: Histopathology
https://www.readbyqxmd.com/read/29076693/angiofibroma-in-a-50-year-old-patient
#12
Syed Shahmeer Raza, Syed Muhammad Owais, Salman Zahid, Ihtisham Ul Haq, Haris Manan, Syeda Fizza Qasim, Farhan Ullah, Asfandiar Shahrukh Hijazi, Osamah Riaz Khan
Juvenile Angiofibroma (JNA) is a benign tumour that tends to bleed and occur in the nasopharynx with most cases occurring in pre-pubertal and adolescent males 10-20 years. We present the case of a 50-year-old male shopkeeper who consulted the ENT out patients' department (OPD) of Khyber Teaching Hospital (KTH) with the chief complaint of right sided nasal obstruction for the last 2.5 months which was associated with two episodes of epistaxis and diplopia which started 2 months back. He complained of right sided frontal and periorbital pain for the last 15 days...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29069259/endoscopic-endonasal-approach-for-mass-resection-of-the-pterygopalatine-fossa
#13
Jan Plzák, Vít Kratochvil, Adam Kešner, Pavol Šurda, Aleš Vlasák, Eduard Zvěřina
OBJECTIVES: Access to the pterygopalatine fossa is very difficult due to its complex anatomy. Therefore, an open approach is traditionally used, but morbidity is unavoidable. To overcome this problem, an endoscopic endonasal approach was developed as a minimally invasive procedure. The surgical aim of the present study was to evaluate the utility of the endoscopic endonasal approach for the management of both benign and malignant tumors of the pterygopalatine fossa. METHOD: We report our experience with the endoscopic endonasal approach for the management of both benign and malignant tumors and summarize recent recommendations...
October 2017: Clinics
https://www.readbyqxmd.com/read/29019747/masses-of-the-nose-nasal-cavity-and-nasopharynx-in-children
#14
Diana P Rodriguez, Emily S Orscheln, Bernadette L Koch
A wide range of masses develop in the nose, nasal cavity, and nasopharynx in children. These lesions may arise from the nasal ala or other structures of the nose, including the mucosa covering any surface of the nasal cavity, the cartilaginous or osseous portion of the nasal septum, the nasal turbinates, and the nasal bones. Lesions may also arise from the nasopharynx or adjacent structures and involve the nose by way of direct extension. The causes of nasal masses in children include congenital and developmental disorders such as congenital nasolacrimal duct mucocele, dermoid cyst, cephalocele, and nasal neuroglial heterotopia; inflammatory and infectious processes such as mucocele, polyp, and pyogenic granuloma; benign neoplasms such as infantile hemangioma and juvenile nasopharyngeal angiofibroma; malignant lesions such as rhabdomyosarcoma and nasopharyngeal carcinoma; and masses related to prior trauma such as septal hematoma...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28929055/the-four-port-bradoo-technique-an-alternative-to-the-modified-endoscopic-denker-s-approach-for-giant-jna
#15
Renuka Bradoo, Anagha Joshi, Kshtij Shah, Tejal Patel, Tanvi Lohiya
The aim of this study is to emphasise the importance of preserving the anterior facial skeleton in angiofibroma surgery and to introduce a new approach by which tumors with far lateral extensions can be operated upon successfully without disruption of the anterior facial skeleton. This is a prospective study conducted at a tertiary referral academic centre. Two patients with extensive juvenile nasopharyngeal angiofibroma with far lateral extensions were recruited and they underwent surgery between July and August 2016...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28887603/molecular-signature-of-tumors-with-monoallelic-13q14-deletion-a-case-series-of-spindle-cell-lipoma-and-genetically-related-tumors-demonstrating-a-link-between-foxo1-status-and-p38-mapk-pathway
#16
Karina Uehara, Fukino Ikehara, Ryo Shibuya, Iwao Nakazato, Mariko Oshiro, Masaya Kiyuna, Yasuka Tanabe, Zensei Toyoda, Kiyoto Kurima, Shinichiro Kina, Masanori Hisaoka, Takao Kinjo
Spindle cell/pleomorphic lipomas (SCLs), cellular angiofibromas (CAFs) and mammary-type myofibroblastomas (MFBs) are rare benign mesenchymal tumors with monoallelic 13q14 deletion. They are predicted to have a common pathogenic mechanism due to shared similar histological and immunohistochemical features; however, pathological consequences of monoallelic 13q14 deletion remain unknown. We previously reported a CAF case with monoallelic 13q14 deletion in which the tumor expressed decreased levels of FOXO1 and RB1, both of which were encoded in 13q14, and increased reactive oxygen species (ROS) levels...
September 8, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28885437/cellular-angiofibroma-of-the-nasopharynx
#17
Zülküf Burak Erdur, Haydar Murat Yener, Mehmet Yilmaz, Ayşegül Batioğlu Karaaltin, Hakki Caner Inan, Elvin Alaskarov, Emine Deniz Gozen
Angiofibroma is a common tumor of the nasopharynx region but cellular type is extremely rare in head and neck. A 13-year-old boy presented with frequent epistaxis and nasal obstruction persisting for 6 months. According to the clinical symptoms and imaging studies juvenile angiofibroma was suspected. Following angiographic embolization total excision of the lesion by midfacial degloving approach was performed. Histological examination revealed that the tumor consisted of staghorn blood vessels and irregular fibrous stroma...
November 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28877055/solitary-fibrous-tumors-of-the-head-and-neck-a-multi-institutional-clinicopathologic-study
#18
MULTICENTER STUDY
Steven C Smith, William E Gooding, Matthew Elkins, Rajiv M Patel, Paul W Harms, Andrew S McDaniel, Nallasivam Palanisamy, Cora Uram-Tuculescu, Bonnie B Balzer, David R Lucas, Raja R Seethala, Jonathan B McHugh
Solitary fibrous tumors (SFTs) of the head and neck are uncommon. Lesions previously diagnosed in the head and neck as hemangiopericytomas (HPCs), giant cell angiofibromas (GCAs), and orbital fibrous histiocytomas (OFHs) are now recognized as within the expanded spectrum of SFTs. To better understand the clinicopathologic profile of head and neck SFTs, we performed a multi-institutional study of 88 examples. There was no sex predilection (F:M ratio 1.2), and the median patient age was 52 years (range: 15 to above 89 y)...
December 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28845691/four-dimensional-ct-angiography-4d-cta-in-the-evaluation-of-juvenile-nasopharyngeal-angiofibromas-comparison-with-digital-subtraction-angiography-dsa-and-surgical-findings
#19
Zebin Xiao, Yingyan Zheng, Jian Li, Dehua Chen, Fang Liu, Dairong Cao
OBJECTIVES: To explore the value of four-dimensional CT angiography (4D-CTA) in the preoperative evaluation of juvenile nasopharyngeal angiofibromas (JNAs) using 320-row volume CT. METHODS: 4D-CTA and DSA data of 18 patients with histopathologically proven JNAs were retrospectively reviewed. The location, extent, feeding vessels and stage of JNAs were assessed by two radiologists independently and blindly. The agreements between both reviewers and between 4D-CTA and surgical findings for assessing the above indicators were analysed, respectively...
December 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28781841/perioperative-airway-management-of-a-16-year-old-boy-with-progressive-airway-obstruction-due-to-juvenile-nasopharyngeal-angiofibroma
#20
Kei Kamiyama, Maiko Satomoto, Kotaro Minami, Yukiko Baba, Koshi Makita
Juvenile nasopharyngeal angiofibroma (JNA) involves difficult anesthetic management because of the risk of massive bleeding, while airway management is rarely a problem in JNA. This report presents an unusual case of JNA causing airway obstruction.
August 2017: Clinical Case Reports
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