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Toll like receptor 3 7 C/A 1377 C/T and hepatitis c

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https://www.readbyqxmd.com/read/28093541/association-of-toll-like-receptor-3-and-toll-like-receptor-9-single-nucleotide-polymorphisms-with-hepatitis-c-virus-infection-and-hepatic-fibrosis-in-egyptian-patients
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Rania A Zayed, Dalia Omran, Doha A Mokhtar, Zinab Zakaria, Sameera Ezzat, Mohamed A Soliman, Lamiaa Mobarak, Hossam El-Sweesy, Ghada Emam
AbstractToll-like receptors (TLRs) are recognized as fundamental contributors to the immune system function against infections. Hepatitis C virus (HCV) infection represents a global health problem especially in Egypt having the highest HCV prevalence worldwide where HCV infection is a continuing epidemic. The aim of the present study was to investigate the possible association between genetic variation in TLR-3 and TLR-9 and HCV infection and hepatic fibrosis in chronic HCV-positive Egyptian patients. The present study included 100 naïve chronic HCV-positive patients and 100 age- and sex-matched healthy controls...
March 2017: American Journal of Tropical Medicine and Hygiene
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