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https://www.readbyqxmd.com/read/29778958/building-on-common-ground-to-address-biodiversity-conflicts-and-foster-collaboration-in-environmental-management
#1
Lou Lecuyer, Rehema M White, Birgit Schmook, Sophie Calmé
Conservation biology faces critical challenges that require collaborative approaches, including novel strategies to support interactions among actors in biodiversity conflicts. The goals of this study were to investigate the concept of common ground across multiple issues and to explore its practical application for the support of environmental management. We conceptually defined common ground as the areas of relevance underlying the suite of issues expressed by people regarding environmental management in a particular context...
May 17, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29777351/development-of-a-patient-reported-outcome-measure-of-recovery-after-abdominal-surgery-a-hypothesized-conceptual-framework
#2
Roshni Alam, Sabrina M Figueiredo, Saba Balvardi, Bénédicte Nauche, Tara Landry, Lawrence Lee, Nancy E Mayo, Liane S Feldman, Julio F Fiore
BACKGROUND: We initiated a research program to develop a novel patient-reported outcome measure (PROM) to assess postoperative recovery from the perspective of abdominal surgery patients. In light of FDA recommendations, the first stage of our program aimed to, based on previous literature and expert input, develop a hypothesized conceptual framework portraying the health domains that are potentially relevant to the process of recovery after abdominal surgery. METHODS: This study was conducted in three phases: (1) systematic review to identify PROMs with measurement properties appraised in the context of recovery after abdominal surgery, (2) content analysis to categorize the health domains covered by the PROMs according to the ICF, and (3) two-round Delphi study to gain expert input regarding which of these health domains are relevant to the process of recovery...
May 17, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29774974/stiffness-reconstruction-methods-for-mr-elastography
#3
Daniel Fovargue, David Nordsletten, Ralph Sinkus
Assessment of tissue stiffness is desirable for clinicians and researchers, as it is well established that pathophysiological mechanisms often alter the structural properties of tissue. Magnetic resonance elastography (MRE) provides an avenue for measuring tissue stiffness and has a long history of clinical application, including staging liver fibrosis and stratifying breast cancer malignancy. A vital component of MRE consists of the reconstruction algorithms used to derive stiffness from wave-motion images by solving inverse problems...
May 18, 2018: NMR in Biomedicine
https://www.readbyqxmd.com/read/29774483/analysis-of-unexplained-carcinoembryonic-antigen-elevation-after-curative-treatment-of-locally-advanced-rectal-cancer
#4
Sung Uk Lee, Eunjin Jwa, Dae Yong Kim, Tae Hyun Kim, Ji Yeon Baek, Yongjun Cha, Hee Jin Chang, Jae Hwan Oh
BACKGROUND: To analyze the causes and patterns of unexplained carcinoembryonic antigen (CEA) elevation after curative treatment in locally advanced rectal cancer patients. METHODS: Among the 1309 locally advanced rectal cancer patients treated with curative resection and radiotherapy between January 2001 and June 2011, 325 patients who postoperatively developed abnormal CEA elevation were reviewed. The unexplained CEA elevation was defined as a CEA level higher than 5 ng/mL with no evidence of cancer recurrence at the time of elevation...
May 17, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29771222/structure-of-health-care-dyad-leadership-an-organization-s-experience
#5
Anurag Saxena, Maura Davies, Don Philippon
Purpose This study aims to explore the structural aspects (roles, responsibilities and reporting) of dyad leadership in one health-care organization (HCO). Design/methodology/approach The perceptions of 32 leaders (17 physician leaders and 15 dyad co-leaders) in formal leadership positions (six first-level with formal authority limited to teams or divisions, 23 middle-level with wider departmental or program responsibility and three senior-level with institution-wide authority) were obtained through focus groups and surveys...
May 8, 2018: Leadership in Health Services
https://www.readbyqxmd.com/read/29769044/visualizing-histopathologic-deep-learning-classification-and-anomaly-detection-using-nonlinear-feature-space-dimensionality-reduction
#6
Kevin Faust, Quin Xie, Dominick Han, Kartikay Goyle, Zoya Volynskaya, Ugljesa Djuric, Phedias Diamandis
BACKGROUND: There is growing interest in utilizing artificial intelligence, and particularly deep learning, for computer vision in histopathology. While accumulating studies highlight expert-level performance of convolutional neural networks (CNNs) on focused classification tasks, most studies rely on probability distribution scores with empirically defined cutoff values based on post-hoc analysis. More generalizable tools that allow humans to visualize histology-based deep learning inferences and decision making are scarce...
May 16, 2018: BMC Bioinformatics
https://www.readbyqxmd.com/read/29768637/phase-transition-induced-pattern-formation-applied-to-basic-research-on-homeopathy-a-systematic-review
#7
Maria Olga Kokornaczyk, Claudia Scherr, Natalia Borisovna Bodrova, Stephan Baumgartner
BACKGROUND:  Methods based on phase-transition-induced pattern formation (PTPF) are increasingly used in medical research. Frequent application fields are medical diagnosis and basic research in homeopathy. Here, we present a systematic review of experimental studies concerning PTPF-based methods applied to homeopathy research. We also aimed at categorizing the PTPF methods included in this review. MATERIALS AND METHODS:  Experimental studies were collected from scientific databases (PubMed, Web of Science, Russian eLibrary) and from experts in the research field in question, following the PRISMA guidelines...
May 16, 2018: Homeopathy: the Journal of the Faculty of Homeopathy
https://www.readbyqxmd.com/read/29765948/congenital-orbital-rhabdomyosarcoma
#8
Masoomeh Eghtedari, Amir Reza Farsiani, Mohammad Reza Bordbar
Rhabdomyosarcoma (RMS) is the most common malignant tumor of the orbit in children, but it is rarely present at birth. We report a large congenital orbital RMS with intracranial extension in a newborn baby. A newborn baby girl was referred to our hospital due to severe right-eye exophthalmia. Imaging studies showed an orbital mass with intracranial extension. Treatment was started with a course of neoadjuvant chemotherapy followed by right orbital exenteration and intracranial resection of the tumor. Histologic examination of the mass showed undifferentiated malignant small-cell tumor...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29765197/impact-of-conjunctival-autograft-on-pterygium-treatment-evaluation-of-related-symptoms-and-patients-satisfaction-after-surgery
#9
Ana Cláudia Viana Wanzeler, Bruna Duarte, Vitor Duarte Moron de Andrade, Monica Alves
Purpose: Pterygium is a fibrovascular condition of the ocular surface that can cause a broad range of irritative and visual symptoms. Controversy exists regarding pterygium mechanisms, management, surgical techniques, adjuvant approaches and impact on patients' quality of life. We performed a retrospective survey focused on the impact of pterygium-related symptoms before surgery and patients' satisfaction after excision surgery followed by conjunctival autograft transplantation with fibrin glue, based on patients' subjective reporting...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29764674/surgical-management-of-patients-with-eagle-syndrome
#10
Frances Mei Hardin, Roy Xiao, Brian B Burkey
OBJECTIVE: Eagle syndrome, a spectrum of disease resulting from an elongated styloid process and/or calcified stylohyoid ligament, lacks standardized recommendations regarding indications for surgical intervention and approach. STUDY DESIGN: Retrospective cohort study. SETTING: Single tertiary care institution. SUBJECTS: Patients treated surgically for Eagle syndrome between January 2011 and June 2017. METHODS: Patients were diagnosed with Eagle syndrome based on thorough clinical workup and assessment...
May 9, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29763884/joint-angle-and-movement-velocity-effects-on-muscle-activity-of-elderly-with-knee-osteoarthritis-categorized-and-probabilistic-analysis
#11
João Pedro Batista, Ligia Maria Facci, Alexandre Roberto Marcondes Pelegrinelli, Sylvie Charlotte Frieda Anneliese von Werder, Daniella Carneiro de Souza, Marcelo Taglietti, Josilainne Marcelino Dias, Catherine Disselhorst-Klug, Jefferson Rosa Cardoso
The aim of the study was to determine the effects of joint angle position and angular velocity on concentric and eccentric knee muscles activity of elderly with osteoarthritis (OA) in a deterministic and probabilistic approach compared to matched controls. Concentric and eccentric muscle activation of vastus medialis (VM) and semitendinous (ST) muscles were recorded of eleven elderly women with knee OA (median (Md (25-75%)) age of 62 years (60-72) and Md of body mass index (BMI) of 26 kg/m2 (24.5-27.2)) and ten controls (Md 65 years (62-69) and Md of BMI 24...
April 27, 2018: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29763533/assessing-risk-for-future-firearms-violence-in-young-people-who-present-to-ed
#12
(no author information available yet)
A new clinical index tool designed specifically for the emergency environment predicts the risk for future firearms violence in young people 14-24 years of age. The approach employs a brief, 10-point instrument that can be administered in one to two minutes, according to investigators. They also note that while the tool is based on data from a single ED in Flint, Ml, the tool should be applicable to urban EDs in regions that have similar characteristics. To create the tool, investigators used data from the Flint Youth Injury Study, an investigation of a group of patients 14-24 years of age who reported using drugs in the previous six months and accessed care at a Level I trauma center...
June 2017: ED Management: the Monthly Update on Emergency Department Management
https://www.readbyqxmd.com/read/29762312/the-influence-of-occupation-on-wellbeing-as-experienced-by-the-elderly-a-systematic-review
#13
Christina Jessen-Winge, Mille Nyboe Petersen, Anne-Le Morville
OBJECTIVE: The objective of this review was to synthesize knowledge regarding which types of occupations the elderly perceive as important to and supporting their overall wellbeing. INTRODUCTION: Being active is an important part of managing the daily challenges of advanced old age. Occupational therapy and occupational science are based on the premise that a person's occupations are intertwined with their health and are thus needed for them to experience a meaningful life and improve their wellbeing...
May 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29761934/assessing-the-heterogeneity-of-autism-spectrum-symptoms-in-a-school-population
#14
Paula Morales-Hidalgo, Pere J Ferrando, Josefa Canals
The aim of the present study was to assess whether the nature of the main autistic features (i.e., social communication problems and repetitive and restrictive patterns) are better conceptualized as dimensional or categorical in a school population. The study was based on the teacher ratings of two different age groups: 2,585 children between the ages of 10 and 12 (Primary Education; PE) and 2,502 children between the ages of 3 and 5 (Nursery Education; NE) from 60 mainstream schools. The analyses were based on Factor Mixture Analysis, a novel approach that combines dimensional and categorical features and prevents spurious latent classes from appearing...
May 15, 2018: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29760862/free-open-access-medical-education-foam-in-emergency-medicine-the-global-distribution-of-users-in-2016
#15
Taylor W Burkholder, Jennifer W Bellows, Renee A King
Introduction: Free open-access medical education (FOAM) is a collection of interactive online medical education resources-free and accessible to students, physicians and other learners. This novel approach to medical education has the potential to reach learners across the globe; however, the extent of its global uptake is unknown. Methods: This descriptive report evaluates the 2016 web analytics data from a convenience sample of FOAM blogs and websites with a focus on emergency medicine (EM) and critical care...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29755531/adjunctive-platelet-rich-plasma-prp-in-infrabony-regenerative-treatment-a-systematic-review-and-rct-s-meta-analysis
#16
REVIEW
Mubashir Saleem, Flavio Pisani, Faisal Maqbool Zahid, Ioannis Georgakopoulos, Teuta Pustina-Krasniqi, Edit Xhajanka, Maher Almasri
Background and Objective: The purpose of this study was to highlight the clinical performance of platelet-rich plasma (PRP) used as an adjunctive tool for regeneration in infrabony periodontal defects using different biomaterials or performing different surgical flap approaches. Comparative evaluation of main clinical outcomes as probing pocket depth reduction, clinical attachment gain, and recession reduction with and without the use of PRP has been analysed. Materials and Methods: According to the focused question, an electronic and hand searching has been performed up to December 2016...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29755453/clec10a-is-a-specific-marker-for-human-cd1c-dendritic-cells-and-enhances-their-toll-like-receptor-7-8-induced-cytokine-secretion
#17
Lukas Heger, Silke Balk, Jennifer J Lühr, Gordon F Heidkamp, Christian H K Lehmann, Lukas Hatscher, Ariawan Purbojo, Arndt Hartmann, Fayna Garcia-Martin, Shin-Ichiro Nishimura, Robert Cesnjevar, Falk Nimmerjahn, Diana Dudziak
Dendritic cells (DCs) are major players for the induction of immune responses. Apart from plasmacytoid DCs (pDCs), human DCs can be categorized into two types of conventional DCs: CD141+ DCs (cDC1) and CD1c+ DCs (cDC2). Defining uniquely expressed surface markers on human immune cells is not only important for the identification of DC subpopulations but also a prerequisite for harnessing the DC subset-specific potential in immunomodulatory approaches, such as antibody-mediated antigen targeting. Although others identified CLEC9A as a specific endocytic receptor for CD141+ DCs, such a receptor for CD1c+ DCs has not been discovered, yet...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29753609/sar-for-gastro-intestinal-absorption-and-blood-brain-barrier-permeation-of-pesticides
#18
Andrey A Toropov, Alla P Toropova, Emilio Benfenati, Jean Lou Dorne
The CORAL software has been applied to the development of classification models for pesticides relative to two pharmacokinetic properties in humans: (i) gastro-intestinal absorption; and (ii) blood-brain barrier permeation. These models were built up using categorical data on pesticide absorption and brain permeation split into training, invisible training, calibration and external validation sets using Monte Carlo simulations. The models were assessed using several random splits into the training and validation sets...
May 10, 2018: Chemico-biological Interactions
https://www.readbyqxmd.com/read/29752924/emergency-contraception-supply-in-australian-pharmacies-after-the-introduction-of-ulipristal-acetate-a-mystery-shopping-mixed-methods-study
#19
Jack Charles Collins, Carl Richard Schneider, Rebekah Jane Moles
OBJECTIVE: To explore the supply of emergency contraception (EC) from Australian community pharmacies after the introduction of ulipristal acetate (UPA), and to explore pharmacists' knowledge, decision-making, attitudes, and beliefs surrounding supplying EC. STUDY DESIGN: A mixed-methods approach of mystery shopping with structured interview was employed. From August-November 2017, 20 pharmacy students mystery-shopped 10 community pharmacies in metropolitan Sydney, Australia, requesting "the morning after pill"...
May 9, 2018: Contraception
https://www.readbyqxmd.com/read/29752802/factors-related-to-fruit-and-vegetable-consumption-at-lunch-among-elementary-students-a-scoping-review
#20
Matthew M Graziose, Ian Yi Han Ang
INTRODUCTION: Few children consume the recommended amount of fruits and vegetables, and schools are a valuable setting for interventions, including programs such as the National School Lunch Program, to increase consumption. Previous research explored factors in this program that influence fruit and vegetable consumption. The objective of this scoping review was to identify, describe, and categorize studies that quantitatively measured the consumption of fruits and vegetables during the school lunch meal among US elementary school students...
May 10, 2018: Preventing Chronic Disease
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