Felipe Morgado, Marlee M Vandewouw, Christopher Hammill, Elizabeth Kelley, Jennifer Crosbie, Russell Schachar, Muhammad Ayub, Robert Nicolson, Stelios Georgiades, Paul Arnold, Alana Iaboni, Azadeh Kushki, Margot J Taylor, Evdokia Anagnostou, Jason P Lerch
The cerebellum, through its connectivity with the cerebral cortex, plays an integral role in regulating cognitive and affective processes, and its dysregulation can result in neurodevelopmental disorder (NDD)-related behavioural deficits. Identifying cerebellar-cerebral functional connectivity (FC) profiles in children with NDDs can provide insight into common connectivity profiles and their correlation to NDD-related behaviours. 479 participants from the Province of Ontario Neurodevelopmental Disorders (POND) network (typically developing = 93, Autism Spectrum Disorder = 172, Attention Deficit/Hyperactivity Disorder = 161, Obsessive-Compulsive Disorder = 53, mean age = 12...
April 3, 2024: Translational Psychiatry