keyword
MENU ▼
Read by QxMD icon Read
search

Aging brain fmri cognition

keyword
https://www.readbyqxmd.com/read/29144224/violence-exposure-and-neural-systems-underlying-working-memory-for-emotional-stimuli-in-youth
#1
Jessica L Jenness, Maya L Rosen, Kelly A Sambrook, Meg J Dennison, Hilary K Lambert, Margaret A Sheridan, Katie A McLaughlin
Violence exposure during childhood is common and associated with poor cognitive and academic functioning. However, little is known about how violence exposure influences cognitive processes that might contribute to these disparities, such as working memory, or their neural underpinnings, particularly for cognitive processes that occur in emotionally salient contexts. We address this gap in a sample of 54 participants aged 8 to 19 years (50% female), half with exposure to interpersonal violence. Participants completed a delayed match to sample task for emotional faces while undergoing functional magnetic resonance imaging scanning...
November 16, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29137644/functional-resonance-magnetic-imaging-fmri-in-adolescents-with-idiopathic-musculoskeletal-pain-a-paradigm-of-experimental-pain
#2
Juliana Molina, Edson Amaro, Liana Guerra Sanches da Rocha, Liliana Jorge, Flavia Heloisa Santos, Claudio A Len
BACKGROUND: Studies on functional magnetic resonance imaging (fMRI) have shown that adults with musculoskeletal pain syndromes tolerate smaller amount of pressure (pain) as well as differences in brain activation patterns in areas related to pain.The objective of this study was to evaluate, through fMRI, the brain activation in adolescents with idiopathic musculoskeletal pain (IMP) while performing an experimental paradigm of pain. METHODS: The study included 10 consecutive adolescents with idiopathic musculoskeletal pain (average age 16...
November 14, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/29126965/brain-state-expression-and-transitions-are-related-to-complex-executive-cognition-in-normative-neurodevelopment
#3
John D Medaglia, Theodore D Satterthwaite, Apoorva Kelkar, Rastko Ciric, Tyler M Moore, Kosha Ruparel, Ruben C Gur, Raquel E Gur, Danielle S Bassett
Adolescence is marked by rapid development of executive function. Mounting evidence suggests that executive function in adults may be driven by dynamic control of neurophysiological processes. Yet, how these dynamics evolve over adolescence and contribute to cognitive development is unknown. In a sample of 780 youth aged 8-22 yr (42.7% male) from the Philadelphia Neurodevelopment Cohort, we use a dynamic graph approach to extract activation states in BOLD fMRI data from 264 brain regions. We construct a graph in which each observation in time is a node and the similarity in brain states at two different times is an edge...
November 7, 2017: NeuroImage
https://www.readbyqxmd.com/read/29124823/differences-between-child-and-adult-large-scale-functional-brain-networks-for-reading-tasks
#4
Xin Liu, Yue Gao, Qiqi Di, Jiali Hu, Chunming Lu, Yun Nan, James R Booth, Li Liu
Reading is an important high-level cognitive function of the human brain, requiring interaction among multiple brain regions. Revealing differences between children's large-scale functional brain networks for reading tasks and those of adults helps us to understand how the functional network changes over reading development. Here we used functional magnetic resonance imaging data of 17 adults (19-28 years old) and 16 children (11-13 years old), and graph theoretical analyses to investigate age-related changes in large-scale functional networks during rhyming and meaning judgment tasks on pairs of visually presented Chinese characters...
November 9, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29108941/both-hyper-and-hypo-activation-to-cognitive-challenge-are-associated-with-increased-beta-amyloid-deposition-in-healthy-aging-a-nonlinear-effect
#5
Chris M Foster, Kristen M Kennedy, Marci M Horn, David A Hoagey, Karen M Rodrigue
Beta-amyloid (Aβ) positive individuals hyper-activate brain regions compared to those not at-risk; however, hyperactivation is then thought to diminish as Alzheimer's disease symptomatology begins, evidencing eventual hypoactivation. It remains unclear when in the disease staging this transition occurs. We hypothesized that differential levels of amyloid burden would be associated with both increased and decreased activation (i.e., a quadratic trajectory) in cognitively-normal adults. Participants (N = 62; aged 51-94) underwent an fMRI spatial distance-judgment task and Amyvid-PET scanning...
November 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/29097755/lasting-deficit-in-inhibitory-control-with-mild-traumatic-brain-injury
#6
Benjamin Xu, Marco Sandrini, Sarah Levy, Rita Volochayev, Oluwole Awosika, John A Butman, Dzung L Pham, Leonardo G Cohen
Being able to focus on a complex task and inhibit unwanted actions or interfering information (i.e., inhibitory control) are essential human cognitive abilities. However, it remains unknown the extent to which mild traumatic brain injury (mTBI) may impact these critical functions. In this study, seventeen patients and age-matched healthy controls (HC) performed a variant of the Stroop task and attention-demanding 4-choice response tasks (4CRT) with identical stimuli but two contexts: one required only routine responses and the other with occasional response conflicts...
November 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29097597/multimodal-imaging-in-rat-model-recapitulates-alzheimer-s-disease-biomarkers-abnormalities
#7
Maxime J Parent, Eduardo R Zimmer, Monica Shin, Min Su Kang, Vladimir S Fonov, Axel Mathieu, Antonio Aliaga, Alexey Kostikov, Sonia Do Carmo, Doris Dea, Judes Poirier, Jean-Paul Soucy, Serge Gauthier, A Claudio Cuello, Pedro Rosa-Neto
Imaging biomarkers are frequently proposed as endpoints for clinical trials targeting brain amyloidosis in Alzheimer's Disease (AD); however, the specific impact of amyloid-β (Aβ) aggregation on biomarker abnormalities remains elusive in AD. Using the McGill-R-Thy1-APP transgenic rat as a model of selective Aβ pathology, we characterized the longitudinal progression of abnormalities in biomarkers commonly used in AD research. Middle-aged (9-11 months) transgenic animals (both male and female) displayed mild spatial memory impairments and disrupted cingulate network connectivity measured by resting-state fMRI, even in the absence of hypometabolism (measured with PET [(18)F]FDG) or detectable fibrillary amyloidosis (measured with PET [(18)F]NAV4694)...
November 2, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29096196/task-evoked-pupil-dilation-and-bold-variance-as-indicators-of-locus-coeruleus-dysfunction
#8
Jeremy A Elman, Matthew S Panizzon, Donald J Hagler, Lisa T Eyler, Eric L Granholm, Christine Fennema-Notestine, Michael J Lyons, Linda K McEvoy, Carol E Franz, Anders M Dale, William S Kremen
Pupillary responses during cognitive tasks are linked to functioning of the locus coeruleus (LC). The LC is an early site of abnormal tau deposition, which may contribute to key aspects of Alzheimer's disease (AD) pathophysiology. We previously found attenuation of pupillary responses to increases in cognitive load in individuals with mild cognitive impairment (MCI), suggesting pupillary responses may provide a biomarker of early risk for AD associated with LC dysfunction. The LC modulates cortical activity through two modes of operation: tonic and phasic...
October 7, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29089622/prognosis-of-hippocampal-function-after-sub-lethal-irradiation-brain-injury-in-patients-with-nasopharyngeal-carcinoma
#9
Sharon Chia-Ju Chen, Yoshifumi Abe, Pen-Tzu Fang, Ya-Ju Hsieh, Yung-I Yang, Tzu-Ying Lu, Shoji Oda, Hiroshi Mitani, Shi-Long Lian, Yu-Chang Tyan, Chih-Jen Huang, Tatsuhiro Hisatsune
This work emphasizes the value of assessing hippocampal function by making a timely MRI-based prognosis following a minor dose of hippocampal irradiation after nasopharyngeal carcinomas (NPC) radiotherapy. A quasi-experiment with case-control design and functional assessments (e.g., neuroimaging analysis with fMRI) was conducted to assess hippocampal function after radiotherapy. We delivered 70 Gy of irradiation to nasopharyngeal carcinomas by 6MV helical radiotherapy and collected data from twenty NPC patients and 24 healthy age-matched subjects...
October 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29084283/increased-engagement-of-the-cognitive-control-network-associated-with-music-training-in-children-during-an-fmri-stroop-task
#10
Matthew Sachs, Jonas Kaplan, Alissa Der Sarkissian, Assal Habibi
Playing a musical instrument engages various sensorimotor processes and draws on cognitive capacities collectively termed executive functions. However, while music training is believed to associated with enhancements in certain cognitive and language abilities, studies that have explored the specific relationship between music and executive function have yielded conflicting results. As part of an ongoing longitudinal study, we investigated the effects of music training on executive function using fMRI and several behavioral tasks, including the Color-Word Stroop task...
2017: PloS One
https://www.readbyqxmd.com/read/29070789/the-electrophysiological-connectome-is-maintained-in-healthy-elders-a-power-envelope-correlation-meg-study
#11
N Coquelet, A Mary, P Peigneux, S Goldman, V Wens, X De Tiège
Functional magnetic resonance imaging (fMRI) studies report age-related changes in resting-state functional connectivity (rsFC), suggesting altered or reorganized connectivity patterns with age. However, age-related changes in neurovascular coupling might also partially account for altered connectivity patterns. Here, we used resting-state magnetoencephalography (MEG) and a connectome approach in carefully selected healthy young adults and elders. The MEG connectome was estimated as rsFC matrices involving forty nodes from six major  resting-state networks...
October 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29065995/mental-flexibility-an-meg-investigation-in-typically-developing-children
#12
Alexandra Mogadam, Anne E Keller, Margot J Taylor, Jason P Lerch, Evdokia Anagnostou, Elizabeth W Pang
Mental flexibility is a core property of cognitive executive functions, relying on an extended frontoparietal network in the brain. fMRI research comparing typically developing children and adults has found that children from an early age recruit the same "classic" brain areas associated with mental flexibility as adults; however, there is evidence that the timing of activation may be different. To investigate the temporal dynamics of brain activity associated with mental flexibility in children, we recruited 22 typically developing children (8-15 years) to complete a set-shifting task in the MEG...
October 20, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/29063504/abnormal-interaction-between-cognitive-control-network-and-affective-network-in-patients-with-end-stage-renal-disease
#13
Junya Mu, Tao Chen, Qianqian Liu, Dun Ding, Xueying Ma, Peng Li, Anmao Li, Mingxia Huang, Zengjun Zhang, Jixin Liu, Ming Zhang
End-stage renal disease (ESRD) is a common complicated disorder that is generally associated with an altered central nervous system and cognitive impairment. Neuroimaging studies have recorded aberrant brain circuits in patients with ESRD that were closely associated with abnormal clinical manifestations. However, whether the altered interaction was within and/or between these circuits is largely unclear. We investigated brain topological organization and/or module interaction by employing resting-state functional magnetic resonance imaging (rs-fMRI) and modularity network analysis in 24 patients with ESRD and 20 age- and gender-matched healthy control (HC) subjects...
October 23, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29050849/neuronal-and-behavioral-effects-of-multi-day-brain-stimulation-and-memory-training
#14
Daria Antonenko, Nadine Külzow, Angelica Sousa, Kristin Prehn, Ulrike Grittner, Agnes Flöel
Strategies for memory enhancement, especially for the older population, are of great scientific and public interest. Here, we aimed at investigating neuronal and behavioral effects of transcranial direct current stimulation (tDCS) paired with memory training. Young and older adults were trained on an object-location-memory task on 3 consecutive days with either anodal or sham tDCS. Recall performance was assessed immediately after training, 1 day and 1 month later, as well as performance on trained function and transfer task...
September 28, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/29046290/re-establishing-brain-networks-in-patients-with-esrd-after-successful-kidney-transplantation
#15
Hui Juan Chen, Jiqiu Wen, Rongfeng Qi, Jianhui Zhong, U Joseph Schoepf, Akos Varga-Szemes, Virginia W Lesslie, Xiang Kong, Yun Fei Wang, Qiang Xu, Zhe Zhang, Xue Li, Guang Ming Lu, Long Jiang Zhang
BACKGROUND AND OBJECTIVES: Cognition in ESRD may be improved by kidney transplantation, but mechanisms are unclear. We explored patterns of resting-state networks with resting-state functional magnetic resonance imaging among patients with ESRD before and after kidney transplantation. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Thirty-seven patients with ESRD scheduled for kidney transplantation and 22 age-, sex-, and education-matched healthy subjects underwent resting-state functional magnetic resonance imaging...
October 18, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29033782/neural-correlates-of-direct-access-trading-in-a-real-stock-market-an-fmri-investigation
#16
GianMario Raggetti, Maria G Ceravolo, Lucrezia Fattobene, Cinzia Di Dio
Background: While financial decision making has been barely explored, no study has previously investigated the neural correlates of individual decisions made by professional traders involved in real stock market negotiations, using their own financial resources. Aim: We sought to detect how different brain areas are modulated by factors like age, expertise, psychological profile (speculative risk seeking or aversion) and, eventually, size and type (Buy/Sell) of stock negotiations, made through Direct Access Trading (DAT) platforms...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29032323/neural-activity-during-traumatic-film-viewing-is-linked-to-endogenous-estradiol-and-hormonal-contraception
#17
Stephan F Miedl, Melanie Wegerer, Hubert Kerschbaum, Jens Blechert, Frank H Wilhelm
Women are at higher risk for Posttraumatic Stress Disorder (PTSD) and recent research has highlighted a modulating role of female sex hormones for cognitive and emotional processes potentially underlying PTSD symptoms. However, studies combining fMRI recordings of brain activity during trauma film viewing with assessment of female sex hormones are missing. The trauma film paradigm - a widely used experimental analogue for trauma exposure - confronts healthy participants with traumatic film clips and thus allows studying peritraumatic processing under laboratory conditions...
October 5, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29031764/combined-resting-state-functional-magnetic-resonance-imaging-and-diffusion-tensor-imaging-study-in-patients-with-idiopathic-restless-legs-syndrome
#18
Yaoyao Zhuo, Yuncheng Wu, Yanhong Xu, Lunbo Lu, Ting Li, Xifu Wang, Kangan Li
OBJECTIVE: Restless legs syndrome (RLS) is a common neurological disorder characterized by an urge to move the legs along with paraesthesia deep within them. In this study, we aimed to use diffusion tensor imaging (DTI) and regional homogeneity (ReHo) to investigate the changes in regional spontaneous brain activity change for RLS patients against age- and gender-matched normal control (NC) subjects. METHODS: A total of 35 RLS patients and 27 age- and gender-matched NC subjects were recruited for group comparison research that used DTI and ReHo techniques...
October 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28988829/age-related-prefrontal-compensatory-mechanisms-for-inhibitory-control-in-the-antisaccade-task
#19
Juan Fernandez-Ruiz, Alicia Peltsch, Nadia Alahyane, Donald C Brien, Brian C Coe, Angeles Garcia, Douglas P Munoz
Cognitive decline during aging includes impairments in frontal executive functions like reduced inhibitory control. However, decline is not uniform across the population, suggesting individual brain response variability to the aging process. Here we tested the hypothesis, within the oculomotor system, that older adults compensate for age-related neural alterations by changing neural activation levels of the oculomotor areas, or even by recruiting additional areas to assist with cognitive performance. We established that the observed changes had to be related to better cognitive performance to be considered as compensatory...
October 5, 2017: NeuroImage
https://www.readbyqxmd.com/read/28987668/abnormal-brain-function-in-neuromyelitis-optica-a-fmri-investigation-of-mpasat
#20
Fei Wang, Yaou Liu, Jianjun Li, Matthew Sondag, Meng Law, Chi-Shing Zee, Huiqing Dong, Kuncheng Li
PURPOSE: Cognitive impairment with the Neuromyelitis Optica (NMO) patients is debated. The present study is to study patterns of brain activation in NMO patients during a pair of task-related fMRI. MATERIALS AND METHODS: We studied 20 patients with NMO and 20 control subjects matched for age, gender, education and handedness. All patients with NMO met the 2006 Wingerchuk diagnostic criteria. The fMRI paradigm included an auditory attention monitoring task and a modified version of the Paced Auditory Serial Addition Task (mPASAT)...
October 2017: European Journal of Radiology
keyword
keyword
88043
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"