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Exercise cognition brain

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https://www.readbyqxmd.com/read/29322428/feasibility-of-the-evidence-based-cognitive-telerehabilitation-program-remind-for-patients-with-primary-brain-tumors
#1
Sophie D van der Linden, Margriet M Sitskoorn, Geert-Jan M Rutten, Karin Gehring
Many patients with primary brain tumors experience cognitive deficits. Cognitive rehabilitation programs focus on alleviating these deficits, but availability of such programs is limited. Our large randomized controlled trial (RCT) demonstrated positive effects of the cognitive rehabilitation program developed by our group. We converted the program into the iPad-based cognitive rehabilitation program ReMind, to increase its accessibility. The app incorporates psychoeducation, strategy training and retraining...
January 10, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29321682/intermittent-metabolic-switching-neuroplasticity-and-brain-health
#2
REVIEW
Mark P Mattson, Keelin Moehl, Nathaniel Ghena, Maggie Schmaedick, Aiwu Cheng
During evolution, individuals whose brains and bodies functioned well in a fasted state were successful in acquiring food, enabling their survival and reproduction. With fasting and extended exercise, liver glycogen stores are depleted and ketones are produced from adipose-cell-derived fatty acids. This metabolic switch in cellular fuel source is accompanied by cellular and molecular adaptations of neural networks in the brain that enhance their functionality and bolster their resistance to stress, injury and disease...
January 11, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29321033/environmental-enrichment-intervention-for-rett-syndrome-an-individually-randomised-stepped-wedge-trial
#3
Jenny Downs, Jenny Rodger, Chen Li, Xuesong Tan, Nan Hu, Kingsley Wong, Nicholas de Klerk, Helen Leonard
BACKGROUND: Rett syndrome is caused by a pathogenic mutation in the MECP2 gene with major consequences for motor and cognitive development. One of the effects of impaired MECP2 function is reduced production of Brain Derived Neurotrophic Factor (BDNF), a protein required for normal neuronal development. When housed in an enriched environment, MECP2 null mice improved motor abilities and increased levels of BDNF in the brain. We investigated the effects of environmental enrichment on gross motor skills and blood BDNF levels in girls with Rett syndrome...
January 10, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29286534/fitness-training-for-cardiorespiratory-conditioning-after-traumatic-brain-injury
#4
REVIEW
Leanne Hassett, Anne M Moseley, Alison R Harmer
BACKGROUND: Reduced cardiorespiratory fitness (cardiorespiratory deconditioning) is a common consequence of traumatic brain injury (TBI). Fitness training may be implemented to address this impairment. OBJECTIVES: The primary objective of this updated review was to evaluate whether fitness training improves cardiorespiratory fitness in people who have sustained a TBI. The secondary objectives were to evaluate whether fitness training improves body function and structure (physical and cognitive impairments, psychological responses resulting from the injury), activity limitations and participation restrictions in people who have sustained a TBI as well as to evaluate its safety, acceptance, feasibility and suitability...
December 29, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29284994/the-role-of-dual-tasking-in-the-assessment-of-gait-cognition-and-community-reintegration-of-veterans-with-mild-traumatic-brain-injury
#5
Azadeh Leland, Kamran Tavakol, Joel Scholten, Debra Mathis, David Maron, Simin Bakhshi
Background: This study focussed on the effect of dual versus single tasking on balance, gait and cognition in veterans with mild traumatic brain injury (mTBI). We examined the correlation between these parameters, with responses to questions on community reintegration activities. Method: 22 male and female veterans (aged 19-65) walked along a narrow and 6.1-meter long path, both at their self-selected and fastest but safe pace under single and dual tasking conditions...
December 2017: Materia Socio-medica
https://www.readbyqxmd.com/read/29282997/development-and-psychometric-properties-of-the-healthy-aging-activity-engagement-scale-haae
#6
Maureen Schmitter-Edgecombe, Richard Lamb, Courtney McAlister, Thao Vo, Kayela Robertson
OBJECTIVES: Accumulating research indicates that engaging in healthy lifestyle behaviors (e.g. exercise, cognitive and social engagement, stress reduction) can prevent illness and disability as people age and improve mental health. The Healthy Aging Activity Engagement (HAAE) scale was developed to holistically assess an individual's level of engagement in healthy aging behaviors across multiple health domains. METHODS: Participants were 275 healthy younger, midlife and older adults...
December 28, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29279427/-exercise-and-brain-function
#7
Takehito Ono, Tomoki Nakashima
Cognitive dysfunction is a public health issue, which is one of the main contributing factors for need-of-care, afflicting patients and their caretakers. It is well accepted that physical activity is in close relationship with brain function. Accumulating data has indicated that exercise training can improve brain functions both directly and indirectly via the alleviation of the diseases underlying, including hypertension and diabetes. Recently, mechanisms bridging brain functions and physical exercises have begun to be clarified...
2018: Clinical Calcium
https://www.readbyqxmd.com/read/29277490/gene-environment-interactions-informing-therapeutic-approaches-to-cognitive-and-affective-disorders
#8
REVIEW
Jake Rogers, Thibault Renoir, Anthony J Hannan
Gene-environment interactions drive experience-dependent changes in the brain that alter cognition, emotion and behaviour. Positive engagement with the environment, through novel experience and physical activity, can improve brain function, although the mechanisms mediating such experience-dependent plasticity remain to be fully elucidated. In this article, we discuss the therapeutic value of environmental stimuli, exercise and environmental enrichment (EE), for cognitive and affective disorders, with implications for the understanding and treatment of depression and anxiety disorders...
December 22, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29260016/association-between-exercise-habits-and-subcortical-gray-matter-volumes-in-healthy-elderly-people-a-population-based-study-in-japan
#9
Mikie Yamamoto, Kenji Wada-Isoe, Fumio Yamashita, Satoko Nakashita, Masafumi Kishi, Kenichiro Tanaka, Mika Yamawaki, Kenji Nakashima
Background and aims: The relationship between exercise and subcortical gray matter volume is not well understood in the elderly population, although reports indicate that exercise may prevent cortical gray matter atrophy. To elucidate this association in the elderly, we measured subcortical gray matter volume and correlated this with volumes to exercise habits in a community-based cohort study in Japan. Methods: Subjects without mild cognitive impairment or dementia (n = 280, 35% male, mean age 73...
June 2017: ENeurologicalSci
https://www.readbyqxmd.com/read/29251839/exercise-cognition-and-the-adolescent-brain
#10
REVIEW
Megan M Herting, Xiaofang Chu
BACKGROUND: Few adolescents engage in the recommended levels of physical activity, and daily exercise levels tend to drastically decrease throughout adolescence. Beyond physical health benefits, regular exercise may also have important implications for the teenage brain and cognitive and academic capabilities. METHODS: This narrative review examines how physical activity and aerobic exercise relate to school performance, cognition, and brain structure and function...
December 1, 2017: Birth Defects Research
https://www.readbyqxmd.com/read/29238394/physical-exercise-as-stabilizer-for-alzheimer-s-disease-cognitive-decline-current-status
#11
Sergio Machado, Alberto Souza de Sá Filho, Matheus Wilbert, Gabriela Barbieri, Victor Almeida, Alexandre Gurgel, Charles V Rosa, Victor Lins, Alexandre Paixão, Kamila Santana, Gabriel Ramos, Geraldo Maranhão Neto, Flá Paes, Nuno Rocha, Eric Murillo-Rodriguez
Introduction: Mental health decline is one of the main responsible factors for augments in health care costs, and diagnosis of Alzheimer's disease (AD). Some studies stated physical exercise is useful for reduction in cognitive decline and AD. Moreover, a recent review argued that evidence are scarce due to few studies published and lack of configuration information of exercise protocol, such as intensity and duration of exercise, number of sessions and other relevant data, to allow appropriate assessment...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29237165/distraction-versus-intensity-the-importance-of-exercise-classes-on-cognitive-performance-in-school
#12
Petra Wollseiffen, Tobias Vogt, Heiko Strüder, Stefan Schneider
OBJECTIVE: The aim of this study was to compare the influence of a class of aerobic exercise and an arts class on brain cortical activity and possible effects on cognitive performance. SUBJECT AND METHODS: Electroencephalography was used to record the electro cortical activity of sixteen (16) school children (8-10 years) before and after an aerobic exercise class, and an arts class. Performance in a standardized assessment of educational attainment (VERA-3) was assessed following both classes...
December 13, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29222290/chronic-organ-failure-in-adult-sickle-cell-disease
#13
REVIEW
Elliott Vichinsky
Sickle cell disease is now a chronic adult illness characterized by progressive multiorgan failure, particularly involving the brain and kidney. The etiology is multifactorial; it includes hemolysis and nitric oxide deficiency. As patients age, most experience neurologic insult. Twenty-five percent of older adults have had a clinical stroke and at least half of the population have had a silent infarct, cortical atrophy, and neurocognitive impairment. Periodic screening with neuroimaging and neurocognitive testing is recommended...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29215907/chemotherapy-and-cognitive-impairment-an-animal-model-approach
#14
Gordon Winocur
A substantial number of cancer survivors who undergo chemotherapy report cognitive disturbances that severely limit daily function (chemobrain). Despite supportive neuropsychological evidence, there is controversy over whether cognitive impairment is caused by the chemotherapy or is the result of potentially confounding factors that include the disease itself, age, and psychological stress. Our research program, conducted on rodents, has confirmed that a range of cognitive processes, mediated in particular by hippocampal and prefrontal brain regions, are affected by anticancer drugs in combination with tumor development and that many of the effects are long lasting...
December 2017: Canadian Journal of Experimental Psychology, Revue Canadienne de Psychologie Expérimentale
https://www.readbyqxmd.com/read/29209201/do-lifestyle-activities-protect-against-cognitive-decline-in-aging-a-review
#15
Gregory J Christie, Tara Hamilton, Bradley D Manor, Norman A S Farb, Faranak Farzan, Andrew Sixsmith, Jean-Jacques Temprado, Sylvain Moreno
The number of patients suffering from dementia is expected to more than triple by the year 2040, and this represents a major challenge to publicly-funded healthcare systems throughout the world. One of the most effective prevention mechanisms against dementia lies in increasing brain- and cognitive-reserve capacity, which has been found to reduce the behavioral severity of dementia symptoms as neurological degeneration progresses. To date though, most of the factors known to enhance this reserve stem from largely immutable history factors, such as level of education and occupational attainment...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29209183/cognitive-flexibility-training-a-large-scale-multimodal-adaptive-active-control-intervention-study-in-healthy-older-adults
#16
Jessika I V Buitenweg, Renate M van de Ven, Sam Prinssen, Jaap M J Murre, K Richard Ridderinkhof
As aging is associated with cognitive decline, particularly in the executive functions, it is essential to effectively improve cognition in older adults. Online cognitive training is currently a popular, though controversial method. Although some changes seem possible in older adults through training, far transfer, and longitudinal maintenance are rarely seen. Based on previous literature we created a unique, state-of-the-art intervention study by incorporating frequent sessions and flexible, novel, adaptive training tasks, along with an active control group...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29204954/chronic-fluoxetine-induces-activity-changes-in-recovery-from-poststroke-anxiety-depression-and-cognitive-impairment
#17
Faranak Vahid-Ansari, Paul R Albert
Poststroke depression (PSD) is a common outcome of stroke that limits recovery and is only partially responsive to chronic antidepressant treatment. In order to elucidate changes in the cortical-limbic circuitry associated with PSD and its treatment, we examined a novel mouse model of persistent PSD. Focal endothelin-1-induced ischemia of the left medial prefrontal cortex (mPFC) in male C57BL6 mice resulted in a chronic anxiety and depression phenotype. Here, we show severe cognitive impairment in spatial learning and memory in the stroke mice...
December 4, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/29203796/aerobic-exercise-and-a-bdnf-mimetic-therapy-rescue-learning-and-memory-in-a-mouse-model-of-down-syndrome
#18
Martina Parrini, Diego Ghezzi, Gabriele Deidda, Lucian Medrihan, Enrico Castroflorio, Micol Alberti, Pietro Baldelli, Laura Cancedda, Andrea Contestabile
Down syndrome (DS) is caused by the triplication of human chromosome 21 and represents the most frequent genetic cause of intellectual disability. The trisomic Ts65Dn mouse model of DS shows synaptic deficits and reproduces the essential cognitive disabilities of the human syndrome. Aerobic exercise improved various neurophysiological dysfunctions in Ts65Dn mice, including hippocampal synaptic deficits, by promoting synaptogenesis and neurotransmission at glutamatergic terminals. Most importantly, the same intervention also prompted the recovery of hippocampal adult neurogenesis and synaptic plasticity and restored cognitive performance in trisomic mice...
December 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29201553/proinflammatory-cytokines-correlate-with-early-exercise-attenuating-anxiety-like-behavior-after-cerebral-ischemia
#19
Qi Zhang, Jingjun Zhang, Yuzhong Yan, Pengyue Zhang, Wei Zhang, Rong Xia
Background and Objective: Stroke may cause neuropsychiatric problems, which have negative effects on cognitive functions and behavior. Exercise plays an important role in reducing the occurrence and development of stroke, the concrete mechanism is not fully clarified. In this study, we attempted to determine whether early treadmill exercise attenuates anxiety-like behavior by regulation of inflammation after brain ischemia. Method: We subjected adult male rats to middle cerebral artery occlusion (MCAO) for 90 min and trained rats started to run on a treadmill from postoperative day 1 to day 14...
November 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29199072/maternal-brain-tnf-%C3%AE-programs-innate-fear-in-the-offspring
#20
Bojana Zupan, Bingfang Liu, Faten Taki, Judit Gal Toth, Miklos Toth
Tumor necrosis factor alpha (TNF-α) is a cytokine that not only coordinates local and systemic immune responses [1, 2] but also regulates neuronal functions. Most prominently, glia-derived TNF-α has been shown to regulate homeostatic synaptic scaling [3-6], but TNF-α-null mice exhibited no apparent cognitive or emotional abnormalities. Instead, we found a TNF-α-dependent intergenerational effect, as mothers with a deficit in TNF-α programmed their offspring to exhibit low innate fear. Cross-fostering and conditional knockout experiments indicated that a TNF-α deficit in the maternal brain, rather than in the hematopoietic system, and during gestation was responsible for the low-fear offspring phenotype...
November 21, 2017: Current Biology: CB
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