Read by QxMD icon Read

strong ion

Elif Şenkuytu, Esra Tanrıverdi Eçik
In the study, the new hexa-bodipy functionalized dendrimeric cyclotriphosphazene conjugates (HBCP 1 and 2) have been successfully synthesized and characterized by using general spectroscopic techniques such as1 H,13 C and31 P NMR spectroscopies. The photophysical and metal sensing properties in THF solutions of dendrimeric cyclotriphosphazene conjugates (HBCP 1 and 2) were investigated by UV-Vis and fluorescence spectroscopies in dilute tetrahydrofuran solutions. These dendrimers showed strong absorption bands 501 and 641nm at low concentration with high molar extinction coefficients...
March 9, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Hans G Rinderknecht, H-S Park, J S Ross, P A Amendt, D P Higginson, S C Wilks, D Haberberger, J Katz, D H Froula, N M Hoffman, G Kagan, B D Keenan, E L Vold
The structure of a strong collisional shock front forming in a plasma is directly probed for the first time in laser-driven gas-jet experiments. Thomson scattering of a 526.5 nm probe beam was used to diagnose temperature and ion velocity distribution in a strong shock (M∼11) propagating through a low-density (ρ∼0.01  mg/cc) plasma composed of hydrogen. A forward-streaming population of ions traveling in excess of the shock velocity was observed to heat and slow down on an unmoving, unshocked population of cold protons, until ultimately the populations merge and begin to thermalize...
March 2, 2018: Physical Review Letters
Fei Li, Zhiguo Xia, Caofeng Pan, Yue Gong, Lin Gu, Quanlin Liu, Jin Z Zhang
The unification of tunable band edge (BE) emission and strong Mn2+ doping luminescence in all-inorganic cesium lead halide perovskite nanocrystals (NCs) CsPbX3 (X = Cl and Br) is of fundamental importance in fine tuning their optical properties. Herein, we demonstrate that, benefiting from the differentiation of the cation/anion exchange rate, ZnBr2 and preformed CsPb1-xCl3:xMn NCs can be used to obtain high Br content Cs(Pb1-x-zZnz)(ClyBr1-y)3:xMn2+ perovskite NCs with strong Mn2+ emission, and Mn2+ substitution ratio can reach about 22%...
March 16, 2018: ACS Applied Materials & Interfaces
A-Ra Hong, Youngsun Kim, Tae Sup Lee, Sehoon Kim, Kwangyeol Lee, Gayoung Kim, Ho Seong Jang
In this study, intense single-band red-emitting upconversion nanophosphors (UCNPs) excited with 800 nm near infrared (NIR) light are reported. When a NaYF4 :Nd,Yb active-shell is formed on the 12.7 nm-sized NaGdF4 :Yb,Ho,Ce UCNP core, the core/shell (C/S) UCNPs show tunable emission from green to red depending on the Ce3+ concentration under excitation with 800 nm NIR light. Thirty mol% Ce3+ -doped C/S UCNPs exhibit single-band red emission peaking at 644 nm via a5 F5 →5 I8 transition of Ho3+ . A high Nd3+ concentration in the shell results in strong absorption at around 800 nm NIR light even though the shell thickness is not large, and small-sized C/S UCNPs (16...
March 16, 2018: ACS Applied Materials & Interfaces
Quan Zhou, Li Hong, Jing Wang
PURPOSE: The aim of this study was to elucidate the molecular mechanisms and to identify the key genes and pathways for pelvic organ prolapse (POP) using bioinformatics analysis. METHODS: The microarray data for GSE53868 included 12 POP and 12 non-POP anterior vaginal wall samples. Differentially expressed genes (DEGs) were identified by GEO2R online tool. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed using the DAVID database, and a DEG-associated protein-protein interaction (PPI) network was constructed using STRING and visualized in Cytoscape...
March 15, 2018: Archives of Gynecology and Obstetrics
Caterina Musolino, Giacomo Oteri, Alessandro Allegra, Manuela Mania, Angela D'Ascola, Angela Avenoso, Vanessa Innao, Andrea Gaetano Allegra, Salvatore Campo
Bisphosphonates are formidable inhibitors of osteoclast-mediated bone resorption employed for therapy of multiple myeloma (MM) subjects with osteolytic lesions. Osteonecrosis of the jaw (ONJ) is an uncommon drug-induced adverse event of these agents. MicroRNAs (miRNAs) are a group of small, noncoding RNAs nucleotides, which are essential post-transcriptional controllers of gene expression. They have a central role in the normal bone development. The goal of our study was to investigate 18 miRNAs, whose targets were previously validated and described in MM subjects without ONJ, in peripheral lymphocytes of MM subjects with bisphosphonate-induced ONJ...
March 15, 2018: Annals of Hematology
Elizabeth A MacDonald, Eric Donovan, Yukitoshi Nishimura, Nathan A Case, D Megan Gillies, Bea Gallardo-Lacourt, William E Archer, Emma L Spanswick, Notanee Bourassa, Martin Connors, Matthew Heavner, Brian Jackel, Burcu Kosar, David J Knudsen, Chris Ratzlaff, Ian Schofield
A glowing ribbon of purple light running east-west in the night sky has recently been observed by citizen scientists. This narrow, subauroral, visible structure, distinct from the traditional auroral oval, was largely undocumented in the scientific literature and little was known about its formation. Amateur photo sequences showed colors distinctly different from common types of aurora and occasionally indicated magnetic field-aligned substructures. Observations from the Swarm satellite as it crossed the arc have revealed an unusual level of electron temperature enhancement and density depletion, along with a strong westward ion flow, indicating that a pronounced subauroral ion drift (SAID) is associated with this structure...
March 2018: Science Advances
Mirko Moroni, M Rocio Servin-Vences, Raluca Fleischer, Oscar Sánchez-Carranza, Gary R Lewin
Mechanosensitive PIEZO ion channels are evolutionarily conserved proteins whose presence is critical for normal physiology in multicellular organisms. Here we show that, in addition to mechanical stimuli, PIEZO channels are also powerfully modulated by voltage and can even switch to a purely voltage-gated mode. Mutations that cause human diseases, such as xerocytosis, profoundly shift voltage sensitivity of PIEZO1 channels toward the resting membrane potential and strongly promote voltage gating. Voltage modulation may be explained by the presence of an inactivation gate in the pore, the opening of which is promoted by outward permeation...
March 15, 2018: Nature Communications
Sean C Edington, Andrea Gonzalez, Thomas R Middendorf, D Brent Halling, Richard W Aldrich, Carlos R Baiz
The Ca2+ -sensing protein calmodulin (CaM) is a popular model of biological ion binding since it is both experimentally tractable and essential to survival in all eukaryotic cells. CaM modulates hundreds of target proteins and is sensitive to complex patterns of Ca2+ exposure, indicating that it functions as a sophisticated dynamic transducer rather than a simple on/off switch. Many details of this transduction function are not well understood. Fourier transform infrared (FTIR) spectroscopy, ultrafast 2D infrared (2D IR) spectroscopy, and electronic structure calculations were used to probe interactions between bound metal ions (Ca2+ and several trivalent lanthanide ions) and the carboxylate groups in CaM's EF-hand ion-coordinating sites...
March 15, 2018: Proceedings of the National Academy of Sciences of the United States of America
Yuan Ding, Kent A Nielsen, Bruno P Nielsen, Niels W Bøje, Rainer H Müller, Sung Min Pyo
Nicotine, obtained from tobacco leaves, has been used to promote the cessation of smoking and reduce the risk of COPD and lung cancer. Incorporating the active in lipid nanoparticles is an effective tool to minimize its irritation potential and to use the particles as intermediate to produce final products. However, as a hydrophilic active, it is a challenge to prepare nicotine loaded lipid nanoparticles with high drug loading. In this study, lipid-drug-conjugates (LDC) were formed by nicotine and different fatty acids to enable the production of sufficiently loaded nicotine lipid nanoparticles...
March 12, 2018: European Journal of Pharmaceutics and Biopharmaceutics
Sebastian Trippel, Joss Wiese, Terry Mullins, Jochen Küpper
Strong quasi-adiabatic laser alignment of the indole-water-dimer clusters, an amino-acid chromophore bound to a single water molecule through a hydrogen bond, was experimentally realized. The alignment was visualized through ion and electron imaging following strong-field ionization. Molecular-frame photoelectron angular distributions showed a clear suppression of the electron yield in the plane of the ionizing laser's polarization, which was analyzed as strong alignment of the molecular cluster with ⟨cos2 θ2D ⟩ ≥ 0...
March 14, 2018: Journal of Chemical Physics
Zhaoxiang Liu, Jinping Yao, Jinming Chen, Bo Xu, Wei Chu, Ya Cheng
The generation of laserlike narrow bandwidth emissions from nitrogen molecular ions (N_{2}^{+}) generated in intense near- and mid infrared femtosecond laser fields has aroused much interest because of the mysterious physics underlying such a phenomenon. Here, we perform a pump-probe measurement on the nonlinear interaction of rotational quantum wave packets of N_{2}^{+} generated in midinfrared (e.g., at a wavelength centered at 1580 nm) femtosecond laser fields with an ultrashort probe pulse whose broad spectrum overlaps both P- and R-branch rotational transition lines between the electronic states N_{2}^{+}(B^{2}Σ_{u}^{+},v^{'}=0) and N_{2}^{+}(X^{2}Σ_{g}^{+},v=0)...
February 23, 2018: Physical Review Letters
Z H Zhong, R X Tang, M Zhou, X H Deng, Y Pang, W R Paterson, B L Giles, J L Burch, R B Tobert, R E Ergun, Y V Khotyaintsev, P-A Lindquist
Secondary flux ropes are suggested to play important roles in energy dissipation and particle acceleration during magnetic reconnection. However, their generation mechanism is not fully understood. In this Letter, we present the first direct evidence that a secondary flux rope was generated due to the evolution of an electron vortex, which was driven by the electron Kelvin-Helmholtz instability in an ion diffusion region as observed by the Magnetospheric Multiscale mission. The subion scale (less than the ion inertial length) flux rope was embedded within the electron vortex, which contained a secondary electron diffusion region at the trailing edge of the flux rope...
February 16, 2018: Physical Review Letters
Alexandre Osmar Ortolan, Ina Oestroem, Giovanni Finoto Caramori, Renato Luis Tame Parreira, Eder Henrique da Silva, F Matthias Bickelhaupt
We have explored and analysed the physical factors through which non-covalent in- teractions in anion sensing based on calixarene-type hosts can be tuned, using dispersion- corrected DFT and Kohn-Sham molecular orbital (KS-MO) theory in conjunction with a canonical energy decomposition analysis (EDA). We find that the host-guest interac- tion can be enhanced through the introduction of strongly electron-withdrawing groups at particular positions of the arene and triazine units in the host molecule as well as by coordination of a metal complex to the arene and triazine rings...
March 15, 2018: Journal of Physical Chemistry. A
Sergej Friesen, Sebastian Krickl, Magdalena Luger, Andreas Nazet, Glenn Hefter, Richard Buchner
Aqueous solutions of five lanthanide salts: LaCl3 , La(NO3 )3 , La2 (SO4 )3 , Eu(NO3 )3 and Eu2 (SO4 )3 have been studied at 25 °C by dielectric relaxation spectroscopy over the frequency range 0.05 ≤ ν/GHz ≤ 89. Detailed analysis of the solvent-related modes located at higher frequencies showed that both La3+ and Eu3+ are strongly hydrated, even including partial formation of a third hydration shell similar to that of Al3+ (aq). Up to two solute-related modes could be detected at lower frequencies, due to the formation of various types of 1 : 1 ion pairs (IPs)...
March 15, 2018: Physical Chemistry Chemical Physics: PCCP
Je Min Yoo, Baekwon Park, Sang Jin Kim, Yong Seok Choi, Sungmin Park, Eun Hye Jeong, Hyukjin Lee, Byung Hee Hong
Ferrous ion-based catalysts have been widely employed to oxidatively destruct the major industrial pollutants such as phenolic compounds through advanced oxidation processes (AOPs). These agents, however, inevitably show several drawbacks including the need for pH adjustment and further purification steps to remove residual salts. Here we report the use of a chemical vapour deposition (CVD) graphene film as a novel metal-free catalyst for the AOP-based degradation of phenols in aqueous solution, which does not require additional steps for salt removal nor external energy to activate the process...
March 15, 2018: Nanoscale
Jagpreet Singh Sidhu, Ashutosh Singh, Neha Garg, Navneet Kaur, Narinder Singh
Thioredoxin Reductase (TrxR) is a redox regulating enzyme which is predestined for the maintenance of redox homeostasis of mammalian cells. However, the elevated level of TrxR is associated with the progress of various types of tumors and therefore, this is a significant target for the detection of cancer cells. Herein, an easily engineered 'Turn ON' fluorescent sensor probe has been synthesized for the detection of TrxR and cell imaging using carbon dots. The emission intensity of fCDs on complexation with Cu2+ ions was drastically quenched...
March 15, 2018: Analyst
Yan Hao, Dawei Chen, Zhiguo Zhang, Ping Zhou, Yunxia Cao, Zhaolian Wei, Xiaofeng Xu, Beili Chen, Weiwei Zou, Mingrong Lv, Dongmei Ji, Xiaojin He
Hearing loss may place a heavy burden on the patient and patient's family. Given the high incidence of hearing loss among newborns and the huge cost of treatment and care (including cochlear implantation), prenatal diagnosis is strongly recommended. Termination of the fetus may be considered as an extreme outcome to the discovery of a potential deaf fetus, and therefore preimplantation genetic diagnosis has become an important option for avoiding the birth of affected children without facing the risk of abortion following prenatal diagnosis...
April 2018: Oncology Letters
Tanziyah Muqeem, Biswarup Ghosh, Vitor Pinto, Angelo C Lepore, Manuel Covarrubias
Presynaptic voltage-gated K+ (Kv) channels in dorsal root ganglion (DRG) neurons are thought to regulate nociceptive synaptic transmission in the spinal dorsal horn. However, the Kv channel subtypes responsible for this critical role have not been identified. The Kv3.4 channel is particularly important because it is robustly expressed in DRG nociceptors, where it regulates action potential (AP) duration. Furthermore, Kv3.4 dysfunction is implicated in the pathophysiology of neuropathic pain in multiple pain models...
March 14, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Arisu Shigeta, Shota Ito, Rina Kaneko, Sahoko Tomida, Keiichi Inoue, Hideki Kandori, Izuru Kawamura
Krokinobacter rhodopsin 2 (KR2), a light-driven Na+ pump, is a dual-functional protein, pumping protons in the absence of Na+ when K+ or larger alkali metal ions are present. A specific mutation in helix A near the extracellular Na+ binding site, H30A, eliminates its proton pumping ability. We induced structural changes in H30A by altering the alkali metal ion bound at the extracellular binding site, and observed a strong electrostatic interaction between the Schiff base and counterion and torsion around the Schiff base as revealed by solid-state nuclear magnetic resonance (NMR) and Fourier transform infrared (FTIR) spectroscopies...
March 14, 2018: Physical Chemistry Chemical Physics: PCCP
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"